• induction
  • Numerous immune regulatory functions have been reported for the IL-17 family of cytokines, presumably due to their induction of many immune signaling molecules. (wikipedia.org)
  • Toll-like receptor 2 stimulation predisposes for IL-10 production and induction of T regulatory lymphocytes Bartonella lipopolysaccharide is a non-toxic, complete blocker of Toll-like receptor 4 (TLR4) The fungal pathogen Candida albicans exhibits a series of molecular patterns that are recognised by different pattern recognition receptors. (wikipedia.org)
  • activation
  • These observations indicate a final maturation-activation state of CD8+ T-lymphocytes in chronic obstructive pulmonary disease and, for the first time, identify a blunted regulatory T-cell response to tobacco smoking in these patients, further supporting a potential involvement of the acquired immune response in the pathogenesis of the disease. (ersjournals.com)
  • Lymphocyte-activation gene 3, also known as LAG-3, is a protein which in humans is encoded by the LAG3 gene. (wikipedia.org)
  • gene
  • Interferon regulatory factor 4 also known as MUM1 is a protein that in humans is encoded by the IRF4 gene, located at 6p25-p23. (wikipedia.org)
  • depleting regulatory T-ce
  • The primary goal of the proposed clinical trial is to eliminate cancer tumor using an autologous cell therapy aiming at mounting an efficient immune anti-tumor response by selectively depleting regulatory T-cell during a controlled amount of time. (knowcancer.com)
  • Tolerance
  • It has been shown that transfer of tolerance to other recipients can be made without further manipulation and that this tolerance transfer depends only on CD4+ T-lymphocytes. (wikipedia.org)
  • intensity
  • After a transient increase during physical exercise of relatively high intensity, the number of circulating T lymphocytes often declines below the initial level after exercise ( 10 , 15 , 34 ). (physiology.org)
  • known
  • CD4+ and CD8+ T-lymphocytes along with other mononuclear leukocytes (their exact function regarding the topic is not known) participate in the rejection. (wikipedia.org)
  • expression
  • Thus exercise-elicited endogenous cortisol effectively augments CXCR4 expression on T lymphocytes, which may account for lymphopenia after exercise. (physiology.org)