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  • induction
  • Numerous immune regulatory functions have been reported for the IL-17 family of cytokines, presumably due to their induction of many immune signaling molecules. (wikipedia.org)
  • Toll-like receptor 2 stimulation predisposes for IL-10 production and induction of T regulatory lymphocytes Bartonella lipopolysaccharide is a non-toxic, complete blocker of Toll-like receptor 4 (TLR4) The fungal pathogen Candida albicans exhibits a series of molecular patterns that are recognised by different pattern recognition receptors. (wikipedia.org)
  • gene
  • In the BW5147 T cell line, we have identified two independent regulatory pathways by which arachidonic acid (20:4) can alter gene expression. (naver.com)
  • Interferon regulatory factor 4 also known as MUM1 is a protein that in humans is encoded by the IRF4 gene, located at 6p25-p23. (wikipedia.org)
  • cell
  • The primary goal of the proposed clinical trial is to eliminate cancer tumor using an autologous cell therapy aiming at mounting an efficient immune anti-tumor response by selectively depleting regulatory T-cell during a controlled amount of time. (knowcancer.com)
  • We therefore evaluated T regulatory cell frequencies and their PD-1 expression in the peripheral blood of long-standing diabetics under basal conditions and after CD3/CD28 stimulation. (mdpi.com)
  • Collectively, the results identify the existence of multiple, independent, intracellular 20:4-mediated regulatory pathways operating simultaneously within this cell type. (naver.com)
  • tolerance
  • It has been shown that transfer of tolerance to other recipients can be made without further manipulation and that this tolerance transfer depends only on CD4+ T-lymphocytes. (wikipedia.org)
  • intensity
  • After a transient increase during physical exercise of relatively high intensity, the number of circulating T lymphocytes often declines below the initial level after exercise ( 10 , 15 , 34 ). (physiology.org)
  • rejection
  • CD4+ and CD8+ T-lymphocytes along with other mononuclear leukocytes (their exact function regarding the topic is not known) participate in the rejection. (wikipedia.org)
  • expression
  • Thus exercise-elicited endogenous cortisol effectively augments CXCR4 expression on T lymphocytes, which may account for lymphopenia after exercise. (physiology.org)
  • protein
  • By using the protein synthesis inhibitor, cycloheximide, we also show that the 20:4-mediated regulatory effects upon SCD2 or c- fos are completely independent of new protein synthesis. (naver.com)
  • numerous
  • Since its discovery, AP-1 has been found to be associated with numerous regulatory and physiological processes, and new relationships are still investigated. (wikipedia.org)
  • model
  • The linear no-threshold model (LNT) is a model used in radiation protection to quantify radiation exposure and set regulatory limits. (wikipedia.org)
  • role
  • There are three members of the ADAR family ADARs 1-3 with ADAR 1 and ADAR 2 being the only enzymatically active members.ADAR3 is thought to have a regulatory role in the brain. (wikipedia.org)