Biosynthesis of peanut stilbenes, including resveratrol as the secondary metabolites, could be enhanced by subjecting the kernels to germination and wound-stress. (scirp.org)
Among those discovered stilbenes, resveratrol is one of the most noticed, due to its virtual biological activities and emerging high values in development of the health-enhancing products. (scirp.org)
Piceatannol, a natural stilbene, is an analog and a metabolite of resveratrol. (oregonstate.edu)
With the aim of setting up a cost-effective and high purity production of resveratrol derivatives, hairy root lines were established from Vitis vinifera cv Pinot Noir 40024 to study the organ-specific production of various stilbenes. (omicsdi.org)
Based on the results, we report that stilbene based compounds in general and resveratrol, in particular, can be promising anti-COVID-19 drug candidates acting through disruption of the spike protein. (covid19criticalcare.com)
Trans-stilbene3
A novel series of 2-arylquinazolinones 7a-o bearing trans -stilbene moiety were designed, synthesized, and evaluated against human breast cancer cell lines including human breast adenocarcinoma (MCF-7 and MDA-MB-231) and human ductal breast epithelial tumor (T-47D). (irost.org)
MECHANSIM: The alkene, trans-stilbene, acts as a nucleophile and the bromine acts as an electrophile. (yourfastadvices.com)
Trans-stilbene occurs as a white crystalline solid at room temperature and is highly soluble in organic solvents. (yourfastadvices.com)
Compounds10
Stilbene may refer to one of the two stereoisomers of 1,2-diphenylethene: (E)-Stilbene (trans isomer) (Z)-Stilbene (cis isomer) Stilbenoids, a class of molecules found in plants 1,1-Diphenylethylene This set index article lists chemical compounds articles associated with the same name. (wikipedia.org)
Z)-Stilbene has a melting point of 5-6 °C (41-43 °F), while (E)-stilbene melts around 125 °C (257 °F), illustrating that the two compounds are quite different. (yourfastadvices.com)
Stilbenes are phenolic compounds that occur in some berries. (yourfastadvices.com)
Phenylpropanoids are the precursors to a range of important plant metabolites such as the cell wall constituent lignin and the secondary metabolites belonging to the flavonoid/stilbene class of compounds. (biomedcentral.com)
Phenylpropionic acids, such as 4-coumaric acid and caffeic acid, can be efficiently converted to stilbene compounds by recombinant E. coli cells expressing plant biosynthetic genes. (biomedcentral.com)
Optimization of precursor conversion and cyclization of the bulky ferulic acid precursor by host metabolic engineering and protein engineering may afford the synthesis of even more structurally diverse stilbene compounds. (biomedcentral.com)
Stilbenes are plant defense compounds known to rapidly accumulate in grapevine and some other plant species in response to microbial infection and several abiotic stresses. (omicsdi.org)
Stilbenes are a major grapevine class of phenolic compounds, known for their biological activities, including anti-inflammatory and antioxidant, but never studied in combination. (omicsdi.org)
Stilbene-based natural compounds as promising drug candidates against COVID-19. (covid19criticalcare.com)
Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity. (nel.edu)
Secondary metabolites2
Biosynthesis of many medicinally important plant secondary metabolites, including stilbenes, is frequently not very well understood and under tight spatial and temporal control, limiting their availability from plant sources. (biomedcentral.com)
Glycosylated stilbenes are biologically active secondary metabolites of plants and have the potential to alleviate a broad range of human diseases. (tmu.edu.tw)
Isomers of stilbene2
There are two isomers of stilbene: E isomer and Z isomer. (yourfastadvices.com)
The method is illustrated using Monte Carlo simulations of isomers of stilbene and halogenated derivatives of propane. (cdc.gov)
Biosynthesis5
As an alternative, we sought to develop an approach for the biosynthesis of diverse stilbenes by engineered recombinant microbial cells. (biomedcentral.com)
A pathway for stilbene biosynthesis was constructed in Escherichia coli with 4-coumaroyl CoA ligase 1 4CL1) from Arabidopsis thaliana and stilbene synthase (STS) cloned from Arachis hypogaea . (biomedcentral.com)
Engineered route to stilbene biosynthesis in E. coli . (biomedcentral.com)
However, there is a lack of information on natural signaling pathways and transcription factors regulating stilbene biosynthesis. (omicsdi.org)
genes positively regulate the stilbene biosynthesis as strong positive transcription regulators and can be used in biotechnological applications for stilbene production or high-quality viticulture and winemaking. (omicsdi.org)
Synthesis2
We report a photoinduced strain-assisted synthesis of main-chain stiff-stilbene polymers by using ring-opening metathesis polymerization (ROMP), activating a macrocyclic π-bond connected to a stiff-stilbene photoswitch through a linker. (bsz-bw.de)
This paper reports the first synthesis of oxyresveratrol 2-O-β-d-glucopyranoside (1) and 2,3,5,4′-tetrahydroxystilbene 2-O-β-d-glucopyranoside (1′), which are stilbene glycosides obtained from the rhizomes of Schoenocaulon officinale and Polygonum multiflorum, respectively. (tmu.edu.tw)
Flavonoids3
As previously shown for total polyphenols and flavonoids, the lower the R-acid content, the higher the total stilbene content. (datapdf.com)
Flavonoids and stilbenes are synthesized from a coenzyme A (CoA) activated phenylpropanoid starter unit and three malonyl-CoA extender units (Fig. 1 ). (biomedcentral.com)
It covers representative metabolites of the structure classes cinnamic acids, flavonoids, and stilbenes and enables the simultaneous separation and quantification of 13 polyphenols within 9 min at concentration levels between 0.1 and 3 mu g/g. (boku.ac.at)
Abstract1
abstract = "The electronic states of open-shell stilbene diradicals were studied. (elsevierpure.com)
Enhanced Stilbene Production and Excretion in Vitis vinifera cv Pinot Noir Hairy Root Cultures. (omicsdi.org)
Derivative1
The structure of thunalbene, the first stilbene derivative isolated so far from an Orchidaceae plant, was established as 3,3'-dihydroxy-5-methoxystilbene from spectral and chemical evidence. (caluniv.ac.in)
Piceatannol1
Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin receptor-dependent insulin signaling in early phase of differentiation. (oregonstate.edu)
Grapevine2
Stilbenes are defense molecules produced by grapevine in response to stresses including various elicitors and signal molecules. (omicsdi.org)
Our results demonstrate the ability of grapevine hairy roots to produce various stilbenes. (omicsdi.org)
Reactive1
Since the linker acts as an external constraint, the photoisomerization to the E-form leads to the stiff-stilbene being strained and thus reactive to ROMP. (bsz-bw.de)
Considerable attention1
Stilbenes have attracted considerable attention due to valuable biological effects with multi-spectrum therapeutic application. (omicsdi.org)
Potent3
The 7 stilbenes exhibited potent antioxidative and antiglycative activities and varied with structure-activity nature. (scirp.org)
It is of merit to demonstrate that peanut kernels as a potent producer could be bio-elicited to biosynthesize a broad spectrum of bioactive stilbenes to prepare BPSP which is effective to extend mouse longevity as science-evidenced by the two long-term animal experiments. (scirp.org)
Tetrahydroxy stilbene glycoside (TSG), a potent antioxidant from the well-known Chinese herb Polygonum multiflorum Thunb. (bvsalud.org)
Experiments1
Biomass increase and stilbene production by roots were monitored during flask experiments. (omicsdi.org)
Natural1
We will report a toxicological analysis of a natural stilbene product, and related analogs, against acaricide-susceptible and -resistant varroa mite populations. (confex.com)
Structure2
Accumulation of tri- and tetraketide lactones from ferulic acid, regardless of the CoA-ligase expressed in E. coli , suggests that STS cannot properly accommodate and fold the tetraketide intermediate to the corresponding stilbene structure. (biomedcentral.com)
Depending on the polyketide synthase activity, chalcone synthase (CHS, EC 2.3.1.74) or stilbene synthase (STS, EC 2.3.1.95), subsequent folding and cyclization of the generated tetraketide intermediate results either in the production of a chalcone or stilbene ring structure. (biomedcentral.com)
Content1
gene also increased the content of stilbenes, although to a lesser extent (in 3.4-4.0 times) in comparison with stilbene levels in the empty vector-transformed calli. (omicsdi.org)
Investigations of the bio-elicited peanut sprout powder (BPSP) addressed on characterization of the comprising stilbenes and effectiveness in longevity extension deserves intensive research. (scirp.org)
Biological1
The methanol extracts of BPSP were medium pressure liquid chromatographic (MPLC) fractionated and semi-preparative HPLC recovered and followed by instrumental identification and biological activity determinations of the isolated stilbenes. (scirp.org)
Form1
In this excited state, the lowest energy form of stilbene has a twisted configuration and only a small barrier to internal rotation exists between the trans and the twist forms. (yourfastadvices.com)
Total1
Whereas a low level of stilbene excretion was measured in controls, addition of MeJA induced excretion of up to 37% of total stilbenes. (omicsdi.org)
Product1
10 mg/L). Ferulic acid, however, was not converted to the expected stilbene product, isorhapontigenin. (biomedcentral.com)
Small1
The small target size for the band 3 stilbene binding site may correspond to the intramembrane domain of the band 3 monomer (52 kDa), which is physically distinct from the cytoplasmic domain (42 kDa). (biu.ac.il)
Produce1
on their capability to produce stilbenes were investigated. (omicsdi.org)
Human1
Radiation inactivation was used to measure the target sizes for binding of disulfonic stilbene anion transport inhibitor 4,4'-dibenzamido-2,2'-disulfonic stilbene (DBDS) and mercurial water transport inhibitor p-chloromercuribenzene sulfonate (pCMBS) to human erythrocytes. (biu.ac.il)
Variety1
Role of the variety and some environmental factors on grape stilbenes. (unicatt.it)
Lower1
Why is the melting point of Z stilbene so much lower than e stilbene? (yourfastadvices.com)