• biology
  • Therefore, the number of publications concerning induced pluripotent stem cells has recently been increasing rapidly, demonstrating that this technology has begun to infiltrate many aspects of stem cell biology and medical applications. (ahajournals.org)
  • Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Cell Biology. (diva-portal.org)
  • The state-funded grants will support some 23 investigators from UConn departments at both the Storrs campus and the Health Center who are already engaged in significant stem cell and regenerative biology research. (uconn.edu)
  • progenitor
  • $3.52 million Directing hES Derived Progenitor Cells into Musculoskeletal Lineages , David W. Rowe, principal investigator, UConn Health Center and UConn. (uconn.edu)
  • vitro
  • In vitro, in the presence of VEGF(165), hAC133(+) cells only adopted a venous and microvascular EC phenotype, while hMAPCs differentiated into both arterial and venous ECs, possibly because hMAPCs expressed significantly more sonic hedgehog (Shh) and its receptors as well as Notch 1 and 3 receptors and some of their ligands. (cun.es)
  • These results represent the first demonstration of adult stem cells with the potential to be differentiated into different types of ECs in vitro and in vivo and provide a useful human model to study arteriovenous specification. (cun.es)
  • proliferation
  • Non-specific suppression of T cell proliferation is mediated by soluble factors such as transforming growth factor (TGF)-β, kynurenine, prostaglandin E2 (PGE2), nitric oxide, haem oxygenase products and insulin-like growth factor binding protein. (comparetrials.com)
  • human
  • In this review, we discuss the perspectives of induced pluripotent stem cell technology for modeling human diseases. (ahajournals.org)
  • $2.5 million Human ES Cell Core at University of Connecticut and Wesleyan University , Ren-He Xu, principal investigator, UConn Health Center. (uconn.edu)
  • $880,000 SMAD4-based ChIP-chip Analysis to Screen Target Genes of BMP and TGF Signaling in Human ES Cells , Ren-He Xu, principal investigator, UConn Health Center. (uconn.edu)
  • $200,000 Pragmatic Assessment of Epigenetic Drift in Human ES Cell Lines , Theodore Rasmussen, principal investigator, Department of Animal Science. (uconn.edu)
  • Research
  • From the Department of Reprogramming Science, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan (N.N., S.Y. (ahajournals.org)
  • These techniques will be able to provide safe and stable seeding cells for research and clinical application. (diva-portal.org)
  • The disbursements are the first made under Connecticut's 10-year, $100 million commitment to fund stem cell research, as authorized by Gov. M. Jodi Rell and the General Assembly in 2005. (uconn.edu)
  • Eight Connecticut-based universities and non-profit institutes submitted 70 research proposals totaling $65 million to the state stem cell panel. (uconn.edu)
  • The plan calls for $1 billion in research funding (about half for work on stem cells) and the creation of a post for a science and technology director. (scienceblogs.com)
  • ethical
  • Last month, a separate group of scientists conducted a peer review evaluating all the applications, and ranked each proposal for the state stem cell panel with respect to ethical and scientific merit. (uconn.edu)
  • Department
  • $200,000 Quantitative Analysis of Molecular Transport and Population Kinetics of Stem Cell Cultivation in a Microfluidic System , Tai-Hsi Fan, principal investigator, Department of Mechanical Engineering. (uconn.edu)
  • function
  • In adulthood, our bodies rely on stem cell function for our health. (fchampalimaud.org)
  • Once better understood, stem cell function can be manipulated as a strategy to develop novel therapies for a wide range of diseases including Alzheimer's disease, Parkinson's disease, cancer, blindness, to name a few. (fchampalimaud.org)
  • various
  • By applying this technology, it is possible to produce pluripotent stem cells from biopsy samples of arbitrarily selected individuals with various genetic backgrounds and to subsequently maintain, expand, and stock these cells. (ahajournals.org)
  • known
  • These microenvironmental anatomical entities are known as stem cell niches, a term coined by Dr Richard Schofield in the late 1970s (1). (fchampalimaud.org)
  • better
  • The study of their microenvironment, and how they behave in vivo, is a very important aspect to address in our journey to better understand and use these special cells. (fchampalimaud.org)