• synthesis
  • citation needed] In both cases, the presence of the spiro center, often with four distinct groups attached, and with its unique aspects of chirality, adds unique challenges to the chemical synthesis of each compound type. (wikipedia.org)
  • A rapid synthesis of title compounds under solvent free conditions using MWI is described. (niscair.res.in)
  • A process for the industrial synthesis and new crystalline form of the compound of formula (I): ##STR00001## Medicinal products containing the same which are. (patents.com)
  • One-Step Synthesis and Structure of an Oligo(spiro-orthocarbonate), J. Am. Chem. (wikipedia.org)
  • Elusive bowtie pinned down - synthesis of spiropentadiene, a carbonaceous compound nicknamed bowtiediene because it is shaped like a bowtie, Science News, July 13, 1991. (wikipedia.org)
  • The study of organic reactions includes probing their scope through use in preparation of target compounds (e.g., natural products, drugs, polymers, etc.) by chemical synthesis, as well as the focused study of the reactivities of individual organic molecules, both in the laboratory and via theoretical (in silico) study. (wikipedia.org)
  • novel
  • Spiro compounds are present throughout the natural world, some cases of which have been exploited to provide tool compounds for biomedical study and to serve as scaffolds for the design of therapeutic agents with novel shapes. (wikipedia.org)
  • The present invention is concerned with novel compounds of formula (I) having 5HT.sub.4-antagonistic properties. (patents.com)
  • Novel diol spiro orthocarbonates derived from glycerol as anti-shrinkage additives for the cationic photopolymerization of epoxy monomers, Polymer International, 59(5), 680-685 (2010), doi:10.1002/pi.2755. (wikipedia.org)
  • isomeric
  • Hence, in the third case, the lack of planarity described above gives rise to what is termed axial chirality in otherwise identical isomeric pair of spiro compounds, because they differ only in the right- versus left-handed "twist" of structurally identical rings (as seen in allenes, sterically hindered biaryls, and alkylidenecycloalkanes as well). (wikipedia.org)
  • spirocyclic
  • The first spirocyclic GP inhibitor (GPI), a glucopyranosylidene-spiro-hydantoin ( A , X = O in Chart 1 ) was disclosed in the mid-nineties [ 17 ] followed by the more easily synthesized thiohydantoin counterpart ( A , X = S) [ 18 , 19 ]. (mdpi.com)
  • An example of a spirocyclic compound is the photochromic switch spiropyran. (wikipedia.org)
  • structurally
  • The bonding patterns open to carbon, with its valence of four-formal single, double, and triple bonds, as well as various structures with delocalized electrons-make the array of organic compounds structurally diverse, and their range of applications enormous. (wikipedia.org)
  • nitrogen
  • The range of chemicals studied in organic chemistry include hydrocarbons (compounds containing only carbon and hydrogen), as well as myriad compositions based always on carbon, but also containing other elements, especially oxygen, nitrogen, sulfur, phosphorus (these included in many organic chemicals in biology) and the radiostable elements of the halogens. (wikipedia.org)
  • wherein
  • A pressure- or heat-sensitive recording material which contains as color former at least one chromano compound of the general formula ##STR1## wherein X1, X2, Z1 and Z2, each independently of the other, represent the group of the formula ##STR2## in which V1 and V2, each independently of the other, represent. (google.com.au)
  • 13. A recording material as claimed in claim 1 wherein at least one of the substituents Y 1 and Y 2 or of the substituents in the ring A represents ##STR73## in the chromano compound. (google.com.au)
  • 13. The organic opto-electronic device of claim 12 , wherein the first electrode comprises a metal-compound electrode. (google.com)
  • 18. The organic opto-electronic device of claim 1 , wherein the spacers comprises silicon nitride, or SiN x , or SiO x , or SiO 2 , or Siliconoxynitride (SiON), or organic compounds, or aluminiumoxide, or aluminiumnitride, or titaniumoxide. (google.com)
  • reactions
  • Reactions of O -peracylated C -(1-bromo-β- d -glucopyranosyl)formamides with thioamides furnished the corresponding glucopyranosylidene-spiro-thiazolin-4-one. (mdpi.com)
  • These compounds undergo intramolecularWittig reactions in boiling benzene to produce highly strained spirocyclobutenederivatives, which spontaneously undergo ring-opening reactions to produce dialkyl (E)-2-[1-(2-oxocyclopentyliden)ethyl]-2-butenedioates. (mdpi.com)
  • Spiropentadiene was synthesised from bistrimethylsilylpropynone 1 by reaction with p-toluenesulfonylhydrazide to tosylhydrazone 2 followed by treatment with sodium cyanoborohydride to allene 3 and followed by two successive reactions with chlorocarbene generated from methyllithium and dichloromethane to spiro compound 5. (wikipedia.org)
  • steroids
  • Spirolactones, also known as steroid-17α-spirolactones, 17α-spirolactosteroids, or simply 17α-spirolactones, are a group of steroids which are both spiro compounds and lactones and which feature these two structural properties combined in the form of a spirolactone ring at the C17α position. (wikipedia.org)
  • solvent
  • 14. A pressure-sensitive recording material as claimed in claim 1, which contains at least one said chromano compound dissolved in an organic solvent. (google.com.au)
  • Tetraethoxymethane can be used as a solvent and for the alkylation of CH-acidic compounds (e.g. phenols and carboxylic acids). (wikipedia.org)
  • inhibitors
  • Glucopyranosylidene-spiro-oxathiazoles ( B , X = S) [ 20 , 21 ] and isoxazolines ( B , X = CH 2 ) [ 22 ] identified some ten years later proved to be submicromolar GPIs and still belong in the top ten most efficient glucose-derived inhibitors of the enzyme. (mdpi.com)
  • Therefore
  • Therefore, this compound is of interest for study: by finding which groups cause the tumor-promoting activity, and removing them, the new compound will only have an anti-proliferation activity, and can be used as a therapy for cancer. (wikipedia.org)
  • crystallography
  • For the strong binding of compounds A to the enzyme, X-ray crystallography of the enzyme-inhibitor complexes revealed the importance of the H-bond donor β-NH, as well as that of the α-carbonyl groups highlighted in red [ 23 , 24 ]. (mdpi.com)
  • constitute
  • e.g., zinc, copper, palladium, nickel, cobalt, titanium and chromium) Finally, organic compounds form the basis of all earthly life and constitute a significant part of human endeavors in chemistry. (wikipedia.org)
  • chemical
  • Tetraethoxymethane is a chemical compound which is formally formed by complete ethylation of the hypothetical orthocarbonic acid C(OH)4 (orthocarboxylic acid violates the Erlenmeyer rule and is unstable in free state). (wikipedia.org)
  • TNP refers to the chemical compound 2,4,6-trinitrophenol, also known as Picric acid. (wikipedia.org)
  • Study of structure includes many physical and chemical methods to determine the chemical composition and the chemical constitution of organic compounds and materials. (wikipedia.org)
  • properties
  • citation needed] As well, the spiro motif is present in various practical compound types (such as dyes), as well as in a wide variety of oligo- and polymeric materials designs, for the unique shapes and properties the spiro center imparts, e.g., in the design of electronically active materials in particular. (wikipedia.org)
  • An attempt was made to unify these properties by the study of compounds C [ 3 ]. (mdpi.com)
  • The antimicrobial properties of the compounds were tested against Gram positive and Gram negative bacteria. (mdpi.com)
  • method
  • Europäische Patentschrift EP 0881212 B1, Production method of aminobenzene compound, Erfinder: H. Hashimoto et al. (wikipedia.org)
  • active
  • A new anti-inflammatory active flavanone glycoside 5,7-dihydroxy-8,4 -dimethoxyflavanone-5-O-a-l-rhamno -pyranosyl-7-O-b-d-arabinopyranosyl-(1 4 )-O-b-d-glucopyranoside A along with a known compound dihydroquercetin-4 ' -methyl ether B have been isolated from the leaves of Echinops echinatus . (niscair.res.in)
  • Both compounds were active as GPIs in the low micromolar concentration range. (mdpi.com)
  • This compounds are active in the cleavage of the RNA model compound HPNP. (wikipedia.org)
  • structure
  • The structure and stereochemistry of the new compounds were established by means of NMR and electronic circular dichroism (ECD) data supported by time-dependent density functional theory ECD (TDDFT-ECD) calculations. (mdpi.com)
  • certain
  • Fenspiride (INN, brand names Eurespal, Pneumorel and others) is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. (wikipedia.org)
  • interest
  • Spiro orthocarbonates (SOCs) are of some industrial interest, as they are used as additives for reducing shrinkage during the polymerization of epoxides (they are used as expanding monomers). (wikipedia.org)