• moiety
  • The spin label moiety was attached to phenytoin either at position 3- N via a carbimidomethyl linkage (Compound II) or at a 4'-phenyl position via an amide linkage (Compounds III-V). Two of the phenyl labels (Compounds III and IV) differed only in the presence of a double bond in the pyrroline ring in Compound IV, and Compound V had the amide linkage reversed as compared with Compound III. (aspetjournals.org)
  • For example, stearic acid labelled with nitroxyl spin label moiety at various carbons (5,7,9,12,13,14 and 16th) with respect to first carbon of carbonyl group have been used to study the flexibility gradient of membrane lipids to understand membrane fluidity conditions at different depths of their lipid bilayer organization. (wikipedia.org)
  • protons
  • In response to the force bringing them back to their equilibrium orientation, the protons undergo a rotating motion (precession), much like a spin wheel under the effect of gravity. (wikipedia.org)
  • Certain nuclei such as 1H (protons), 2H, 3He, 23Na or 31P, have a non-zero spin and therefore a magnetic moment. (wikipedia.org)
  • relaxation
  • Recently, spin-labelling has also been used to probe chemical local environment in NMR itself, in a technique known as Paramagnetic Relaxation Enhancement (PRE). (wikipedia.org)
  • Each tissue returns to its equilibrium state after excitation by the independent processes of T1 (spin-lattice) and T2 (spin-spin) relaxation. (wikipedia.org)
  • When the area of the reading gradient is equal to that of the mismatching gradient, the spins will have a coherent new phase (except for the effects of T2* relaxation), and therefore a signal will be detectable again. (wikipedia.org)
  • inversion
  • Examples of these recent improvements are T* 2-weighted turbo spin-echo (T2 TSE MRI), double inversion recovery MRI (DIR-MRI) or phase-sensitive inversion recovery MRI (PSIR-MRI), all of them able to improve imaging of brain lesions. (wikipedia.org)
  • sequences
  • Dynamic spin labeling angiography (DSLA) sequences were implemented and tested on a clinical scanner. (hu-berlin.de)
  • While spoiled gradient-echo sequences refer to a steady state of the longitudinal magnetization only, SSFP gradient-echo sequences include transverse coherences (magnetizations) from overlapping multi-order spin echoes and stimulated echoes. (wikipedia.org)
  • Pulses
  • Patients with some metal implants, cochlear implants, and cardiac pacemakers are prevented from having an MRI scan due to effects of the strong magnetic field and powerful radio frequency pulses unless the device they carry is labeled MR-Conditional. (wikipedia.org)
  • studies
  • V. Studies with salicylic acid and phenylbutazone, known competitors of phenytoin binding, showed that the competition of spin label II paralleled that of [ 14 C]phenytoin more than did the 4'-phenyl labels (III-V). These results suggest that the phenyl rings play a significant role in the binding of phenytoin to albumin. (aspetjournals.org)
  • magnetic field
  • Because the magnetic label decays with the blood T1 (typically between 1.2 and 1.8 s at clinical magnetic field strengths), the ASL signal will not accurately represent CBF in these regions under normal operating conditions. (ahajournals.org)
  • When these spins are placed in a strong external magnetic field they precess around an axis along the direction of the field. (wikipedia.org)
  • echo
  • This signal takes the name of echo or more specifically of gradient echo signal, because it is produced by rephasing due to a gradient (unlike the spin echo signal whose rephasing is due to a radiofrequency pulse). (wikipedia.org)
  • A sequence of the spin echo type must instead wait for the exhaustion of the signal that is formed spontaneously after the application of the excitation impulse before it can produce an echo (free induction decay). (wikipedia.org)
  • For comparison purposes, the repetition time of a gradient echo sequence is of the order of 3 milliseconds, versus about 30 ms of a spin echo sequence. (wikipedia.org)
  • gradient
  • This gradient modifies the spin phase in a spatially dependent manner, so that at the end of the gradient the signal will be completely canceled because the coherence between the spins will be completely destroyed. (wikipedia.org)
  • Australian
  • For the Australian record label of the same name, see Spin Records (Australian label). (wikipedia.org)
  • Launched in late 1965 with the single "Someday" by former Aztecs guitarist Tony Barber, the label was originally called Everybody's, which was also the name of the popular teen magazine published by the Packer family's Australian Consolidated Press. (wikipedia.org)
  • According to Australian historian Bill Casey, the overt cross-promotion reportedly met with resistance from commercial radio, so the label was rebadged as "Spin" after only four singles. (wikipedia.org)
  • Spin releases played an important part in Festival's business in this period, releasing successful albums and singles including the 1969 hit single "Mr Guy Fawkes" by The Dave Miller Set and the original Australian cast recording of the rock musical Hair, which became the first Australian cast recording to earn a Gold Record award. (wikipedia.org)
  • Through Kipner, Spin was also able to secure the lucrative Australian release rights to the Bee Gees' Polydor recordings from 1967 until the Spin label folded in 1973. (wikipedia.org)
  • In 1966 Spin played a pivotal role in the Bee Gees story, issuing the group's final batch of Australian singles, including their first major Australian hit, "Spicks and Specks", released in September that year. (wikipedia.org)
  • transition
  • For first-row transition metals the magnitude of μeff is, to a first approximation, a simple function of the number of unpaired electrons, the spin-only formula. (wikipedia.org)
  • For the heavier transition metals, lanthanides and actinides, spin-orbit coupling cannot be ignored. (wikipedia.org)
  • versus
  • T1 is thus associated with the enthalpy of the spin system, or the number of nuclei with parallel versus anti-parallel spin. (wikipedia.org)
  • patients
  • Two post labeling delay time (PLD) pcASL on 3.0-Tesla MRI scanner system were performed with patients in the resting awake state. (frontiersin.org)
  • role
  • From 1967 onwards, following the collapse of Ivan Dayman's Sunshine label, its acquisition by Festival, and his subsequent appointment as a Festival house producer, musician-composer-producer Pat Aulton took on a central role in Spin's productions, and he produced a large proportion of the label's output in the late '60s and early '70s. (wikipedia.org)