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  • oocyte
  • The oocyte is pierced through the oolemma and the sperm is directed into the inner part of the oocyte (cytoplasm). (wikipedia.org)
  • The sperm is then released into the oocyte. (wikipedia.org)
  • Comet assay), both naturally and in the laboratory, and the procedures by which these sperm are injected directly into an oocyte. (springer.com)
  • The results of this study emphasize the importance of selecting good quality sperm for oocyte injection, especially in cases involving very severe oligozoospermia. (biomedsearch.com)
  • This treatment may be necessary as globozoospermic sperm can be less likely to activate the oocyte, an important stage in fertilisation. (wikipedia.org)
  • citation needed] The Institute's American activities involve a large donor egg program, one of the world's major group of sperm banks and egg banks, one of America's most active preimplantation genetics testing centers, and oocyte cryopreservation via vitrification in addition to more conventional IVF, infertility, and genetic services. (wikipedia.org)
  • Procedures performed on sex cells before fertilization may instead be referred to as methods of oocyte selection or sperm selection, although the methods and aims partly overlap with PGD. (wikipedia.org)
  • Schatten's work on fertilization examines the differential inheritance of cellular components contributed by the sperm and egg, respectively, as well as the program of oocyte activation and cell division during meiosis and mitosis. (wikipedia.org)
  • infertility
  • This procedure is most commonly used to overcome male infertility problems, although it may also be used where eggs cannot easily be penetrated by sperm, and occasionally in addition to sperm donation . (wikipedia.org)
  • Bringing together the latest evidence and written by international leaders in the field, Intracytoplasmic Sperm Injection: Indications, Techniques and Applications is a unique and accessible resource for reproductive endocrinologists, andrologists, geneticists and infertility practitioners and researchers alike. (springer.com)
  • This procedure is useful when there is severe male factor infertility, when there has been failure of fertilization in a prior IVF attempt, or if testing suggests a deficit in the fertilizing capacity of the sperm. (midwestfertility.com)
  • Defective sperm function remains the single most important cause of human infertility. (wikipedia.org)
  • It is thought that infertility in this type of globozoospermia is due to poor mobility of the sperm resulting in slow movement and difficulty fertilising the egg. (wikipedia.org)
  • The development of intracytoplasmic sperm injection made conception a possibility for patients with a variety of male infertility conditions, including globozoospermia. (wikipedia.org)
  • Some of his work, such as cytoplasmic transfer, an attempt to boost development using the cytoplasm of donor eggs to supplement eggs from certain infertility patients, and single sperm freezing, has caused considerable ethical debate. (wikipedia.org)
  • The realization that the specific histologic abnormality observed on testis biopsy has no definite correlation to either the etiology of infertility or to the ability to find sperm for assisted reproduction. (wikipedia.org)
  • Semen
  • Based on semen analysis, the volume was determined to be 3.4 cc, with a concentration of 2 × 10 6 /mL, 73% immotility, and 99% sperm with head and neck anomalies. (hindawi.com)
  • The presence of round headed sperm in a semen analysis sample confirms the diagnosis of globozoospermia. (wikipedia.org)
  • testes
  • It can be used to help men who have a total blockage of any part of the male tubing from the testes as sperm can be 'sucked' directly from the blocked tubing or from the testicle itself. (essentialparent.com)
  • testis
  • Prior to FNA Mapping, testis biopsy was the major procedure for determining the quality of sperm presence. (wikipedia.org)
  • Testis biopsy is a more invasive procedure than FNA Mapping, and studies have shown that FNA Mapping provides better and more complete information about sperm presence. (wikipedia.org)
  • morphology
  • Even with severe teratozoospermia, microscopy can still detect the few sperm cells that have a "normal" morphology, allowing for optimal success rate. (wikipedia.org)
  • retrieval
  • There are no risks to the male partner once the sperm has been obtained - and only negligible risks if sperm retrieval techniques are used. (scrcivf.com)
  • This technique has been important because it has improved identification of men who are likely to have a successful sperm retrieval while at the same time avoiding costly and unnecessary assisted reproductive techniques. (wikipedia.org)
  • FNA Mapping failed to diagnose the degree of "patchiness" of sperm production in azoospermic men and determine, among other things, whether a sperm retrieval would succeed in a specific patient. (wikipedia.org)
  • Technique
  • This technique may be suggested if fewer than 100,000 sperm may be capable of being retrieved for routine IVF, or in cases where very few sperm shows adequate movement. (essentialparent.com)
  • developed MicroSort, an important flow-cytometric human sperm separation technique for preconceptual gender selection, which has already produced over 1,000 births. (wikipedia.org)
  • eggs
  • Your spouse may produce a sperm sample himself by ejaculating into a cup on the same day as your eggs are collected. (healthsparks.org)
  • male
  • Unfortunately, there are many couples in which the male simply does not have enough active sperm to fertilize the egg. (midwestfertility.com)
  • severe
  • Globozoospermia (also known as round-headed sperm syndrome) is a rare and severe form of monomorphic teratozoospermia. (wikipedia.org)
  • oocyte
  • Fishel and colleagues went on to offer direct injection of sperm into the cytoplasm of the oocyte, or 'DISCO', as an alternative treatment for patients for whom SUZI had failed. (wikipedia.org)
  • Sperm entry causes calcium release into the oocyte. (wikipedia.org)
  • IP3 and DAG are produced from the cleavage of PIP2 by phospholipase C. However, another hypothesis is that a soluble 'sperm factor' diffuses from the sperm into the egg cytosol upon sperm-oocyte fusion. (wikipedia.org)
  • Once PLCζ is introduced into the oocyte by the sperm cell, it cleaves phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) into diacyl glycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). (wikipedia.org)
  • biopsy
  • Prior to FNA Mapping, testis biopsy was the major procedure for determining the quality of sperm presence. (wikipedia.org)
  • Testis biopsy is a more invasive procedure than FNA Mapping, and studies have shown that FNA Mapping provides better and more complete information about sperm presence. (wikipedia.org)
  • protein
  • Activation of the ovum includes the following events: Cortical reaction to block against other sperm cells Activation of egg metabolism Reactivation of meiosis DNA synthesis The sperm may trigger egg activation via the interaction between a sperm protein and an egg surface receptor. (wikipedia.org)
  • The hyalin forms a layer adjacent to the plasma membrane and the peroxidases cross-link the protein in the vitelline membrane to harden it and make it impenetrable to sperm. (wikipedia.org)
  • process
  • While he was at the Worcester Foundation for Experimental Biology as a Dr. M.C. Chang's postdoctoral fellow (1960-1964), he witnessed and recorded the entire process of sperm penetration through the zona pellucida and fusion with the egg proper in living (hamster) egg, which was the first in mammals. (wikipedia.org)
  • daily
  • The main formulations of progesterone or progestins for luteal support are: Formulations for intramuscular administrations Vaginal tablets or other inserts for intravaginal administration, such as endometrin While daily intramuscular injections of progesterone-in-oil (PIO) have been the standard route of administration, PIO injections are not FDA-approved for use in pregnancy. (wikipedia.org)
  • quality
  • Additionally, quality control of spermatozoa is much worse than for the ovum, as many sperm are released whereas only one dominant follicle is released per cycle. (wikipedia.org)