• Solitary fibrous tumor (SFT), also known as fibrous tumor of the pleura, is a rare mesenchymal tumor originating in the pleura or at virtually any site in the soft tissue including seminal vesicle. (wikipedia.org)
  • Robinson LA. Solitary fibrous tumor of the pleura. (wikipedia.org)
  • Briselli M, Mark EJ, Dickersin GR. Solitary fibrous tumors of the pleura: eight new cases and review of 360 cases in the literature" Cancer 1981;47:2678-89. (wikipedia.org)
  • Solitary fibrous tumor (SFT) is a noncancerous tumor of the lining of the lung and chest cavity, an area called the pleura. (medlineplus.gov)
  • However, these tumors are commonly found in the pleura, which is the area in the lining of the lung and chest cavity. (naturalpedia.com)
  • In rare cases, solitary fibrous tumors of soft tissue may cause hypoglycemia, while the side effects of solitary fibrous tumors in the pleura include chest pain, a persistent cough, and shortness of breath. (naturalpedia.com)
  • Solitary fibrous tumors in the pleura can cause chest pain, a persistent cough, and shortness of breath. (naturalpedia.com)
  • Histologically, the tumor was diagnosed as a cellular variant of solitary fibrous tumor of the pleura, with branching "staghorn" vessels and hypervascularity. (scirp.org)
  • Solitary Fibrous Tumor of the Pleura: An Analysis of Forty Patients," Journal of Thoracic Diseases, Vol. 4, No. 2, 2012, pp. 146-154. (scirp.org)
  • Solitary fibrous tumors of the pleura: clinical characteristics, surgical treatment and outcome. (nih.gov)
  • Solitary fibrous tumor (SFT) is a neoplasm typically arising in the pleura. (europeanreview.org)
  • Solitary fibrous tumor (SFT) is an uncommon mesenchymal neoplasm that arises primarily from the pleura. (johnshopkins.edu)
  • Aims: To clarify the association of p53 and CD34 expression with development of malignant solitary fibrous tumour we have studied 10 cases of solitary fibrous tumour arising in the pleura, retroperitoneum and pelvic cavity with clinicopathological features of malignancy. (fujita-hu.ac.jp)
  • A new World Health Organization (WHO) Classification of Tumors of the Pleura has recently been published. (nih.gov)
  • Finally, desmoid type fibromatosis, a locally aggressive tumor that can present in the pleura, has been shown to frequently have CTNNB1 gene mutations and express β-catenin by immunohistochemistry. (nih.gov)
  • Solitary fibrous tumors are uncommon soft tissue tumors initially reported only in the pleura but, in recent years, they have been described at many extra pleural sites, such as mediastinum. (omicsdi.org)
  • Neoplasia poco frecuente, generalmente benigna, derivada de los fibroblastos mesenquimatosos localizados en la zona submesotelial de la PLEURA. (bvsalud.org)
  • SFTs are tumors of mesenchymal origin. (medscape.com)
  • Solitary fibrous tumors are mostly noncancerous overgrowth arising from the mesenchymal tissue. (naturalpedia.com)
  • SFTs are malignant tumors of mesenchymal origin that occur in the extremities. (medscape.com)
  • Solitary fibrous tumor (SFT), also previously known as hemangiopericytoma, is a rare mesenchymal neoplasm of fibroblastic origin, accounting for less than 2% of all soft tissue tumors [1] . (axisneuromonitoring.com)
  • Solitary fibrous tumor is a rare mesenchymal tumor of the urinary bladder, but should always be considered in the differential diagnosis of spindle cell neoplasms encountered in the lower genital tract. (europeanreview.org)
  • We describe areas where major inroads were initially achieved by targeting angiogenesis and by unraveling pathways in the heterogeneous tumors of mesenchymal origin-spurred by the identification of c-Kit-activating mutations in GIST and the regressions that ensued when tumors harboring these mutations were exposed to the tyrosine kinase inhibitor imatinib (Gleevec). (cancernetwork.com)
  • Here, in Part I, we describe areas where major inroads were initially achieved by targeting angiogenesis (central to the biology of renal cell carcinoma and hepatocellular cancer) and by unraveling pathways in the heterogeneous tumors of mesenchymal origin-spurred by the identification of c-Kit-activating mutations in gastrointestinal stromal tumors (GIST) and the regressions that ensued when tumors harboring these mutations were exposed to the tyrosine kinase inhibitor imatinib (Gleevec). (cancernetwork.com)
  • BACKGROUND: Solitary fibrous tumours (SFT) are mesenchymal neoplasias rarely found in the orbit. (uzh.ch)
  • Hemangiopericytoma Myopericytoma Gross pathology of an atypical solitary fibrous tumor, evidenced by some deeply yellow necrotic areas Solitary fibrous tumor - low magnification. (wikipedia.org)
  • The tumor thus resembled a chest wall hemangiopericytoma. (scirp.org)
  • Penel N, Amela EY, Decanter G, Robin YM, Marec-Berard P. Solitary fibrous tumors and so-called hemangiopericytoma. (medscape.com)
  • Fat forming solitary fibrous tumor, previously known as lipomatous hemangiopericytoma, is a rare variant of solitary fibrous tumor (SFT) ( Korean J Pathol 2014;48:69 ). (pathologyoutlines.com)
  • Another group of tumors once thought to arise from cells around blood vessels, hemangiopericytoma, is now termed solitary fibrous tumor/hemangiopericytoma, since the tumors all appear to be very similar in terms of their biology. (sarctrials.org)
  • Meningeal solitary fibrous tumor/hemangiopericytoma: Emphasizing on STAT 6 immunohistochemistry. (biocare.net)
  • However, over time, the staghorn-branching vascular pattern representative of HPC was found to be present at least focally in 15% of all soft-tissue tumors and was more of a characteristic histopathologic pattern than a specific clinicopathologic entity. (medscape.com)
  • [ 8 ] The 2020 WHO classification of soft-tissue tumors listed SFT as an intermediate (rarely metastasizing) tumor. (medscape.com)
  • Soft-tissue SFTs represent only about 1-2% of all soft-tissue tumors. (medscape.com)
  • Ren MY, Li J, Wu YX, Li RM, Zhang C, Liu LM, Wang JJ, Gao Y. Clinical characteristics and prognosis of orbital solitary fibrous tumor in patients from a Chinese tertiary eye hospital. (wjgnet.com)
  • Vilardell F, Huerva V, Abó A, Sánchez MC, Matias-Guiu X (2014) Orbital Solitary Fibrous Tumor: Report of a Three Cases Series. (scitechnol.com)
  • Solitary fibrous tumor (SFT) was first described in 1870 by Wagner and further established in 1931 by Klemperer and Rabin as a pleural neoplasm. (medscape.com)
  • Solitary fibrous tumour (SFT) is an uncommon neoplasm at the orbital level that behaves in benign way in most cases [ 1 ]. (scitechnol.com)
  • Prognosis of this neoplasm is obscure and long-term follow-up is required for all cases of solitary fibrous tumor. (europeanreview.org)
  • Due to this change, tumor grades more accurately reflect the cellular behavior and subsequent clinical course of each neoplasm. (medscape.com)
  • While the terminology implies a benign neoplasm, most if not all fibromas represent reactive focal fibrous hyperplasia due to trauma or local irritation. (medscape.com)
  • It is an uncommon benign fibrous neoplasm that occurs most commonly in the skin and may be solitary or multifocal. (medscape.com)
  • In the current report we present three cases of solitary fibrous tumors of the orbital area that we have seen in a relatively short lapse of time. (scitechnol.com)
  • 1,2) Nuclear expression of STAT6 is found in nearly all cases of solitary fibrous tumor (SFT) and is very limited in other soft tissue neoplasms making it a highly sensitive and specific immunohistochemical marker for SFT and may help to distinguish this tumor type from histologic mimics. (biocare.net)
  • High-resolution computed tomography scan of the thorax showed a 19.5 cm × 16.6 cm × 23.8 cm mass in the left hemithorax, and a microscopic examination of a biopsy specimen of which was consistent with the diagnosis of solitary fibrous tumor. (endocrinolrespract.org)
  • Post-operatively, histopatho- logical diagnosis of solitary fibrous tumor was confirmed. (endocrinolrespract.org)
  • Although CD34 is a useful marker in the diagnosis of solitary fibrous tumour, one should bear in mind that its expression can be lost in high-grade tumours. (fujita-hu.ac.jp)
  • On one end, a fibrous form is characterized by hyalinized, thick-walled vessels with opened lumina and strong CD34 reactivity. (medscape.com)
  • Immunohistochemical studies showed CD34 positivity in seven, but three of them showed marked diminution or complete loss of CD34 expression in high-grade loci or a recurrent tumour. (fujita-hu.ac.jp)
  • The tumor cells are CD34 and vimentin positive. (medscape.com)
  • The treatment of choice for both benign and malignant SFT is complete en bloc surgical resection. (wikipedia.org)
  • We present a case report of a 65-year-old woman who underwent resection of a chest wall tumor. (scirp.org)
  • It is diagnosed using immunohistochemical technique and the treatment of choice is surgical resection of the tumour in order to prevent recurrences. (scitechnol.com)
  • Usually, local resection of the tumour is sufficient. (scitechnol.com)
  • However, in some situations, infiltration of the tumour requires more extensive resection of adjacent tissues. (scitechnol.com)
  • As far as possible, treatment involves complete resection as the presence of remnants of intraorbital tumour tissue after the operation carries the risk of causing recurrence of the tumour and can even undergo transformation by becoming malignant [ 3 ]. (scitechnol.com)
  • Anterior mediastinal solitary fibrous tumor resection by da Vinci® Surgical System in obese patient. (omicsdi.org)
  • The treatment of choice is the extensive surgical resection that is curative for most benign lesions.We present the case of solitary fibrous tumor of the anterior mediastinum in obese patient (BMI: 34.3) undergoing complete surgical resection by robotic-assisted thoracoscopic surgery with da Vinci® Surgical System.Robotic-assisted thoracoscopic surgery with da Vinci® Surgical System is an interesting option for obese patient, at higher risk for deep sternal wound infection. (omicsdi.org)
  • To achieve negative resection margins, the width of the tumor-free margins and infiltrating depth are two essential factors to be considered for complete excision for both WLE and MMS surgical techniques. (thieme-connect.de)
  • A right nephrectomy with resection of the mass demonstrated a malignant solitary fibrous tumor. (medscape.com)
  • Definitive management of hypoglycemia associated with paraneoplastic production of IGF-2 consists of resection of the tumor responsible for IGF-2 production. (medscape.com)
  • ABSTRACT: Nerve sheath myxomas (NEUROTHEKEOMA) are uncommon tumors of nerve sheet origin. (scirp.org)
  • When hypoglycemia does occur in such individuals, an uncommon but important diagnosis to consider is non-islet cell tumor hypoglycemia (NICTH). (medscape.com)
  • Moreover, the fibrous nature of the tumor has given rise to various other names, such as pleural fibroma, submesothelial fibroma, and localized fibrous tumor. (medscape.com)
  • The fibroma, also referred to as irritation fibroma, is by far the most common of the oral fibrous tumorlike growths. (medscape.com)
  • The clinical differential diagnosis of a fibroma depends on its clinical presentation and location and includes giant cell fibroma, neurofibroma , peripheral giant cell granuloma , schwannoma, granular cell tumor, mucocele , and benign and malignant salivary gland tumors (eg, see Salivary Gland Neoplasms ). (medscape.com)
  • Histologically, a fibroma is an unencapsulated, solid, nodular mass of dense and sometimes hyalinized fibrous connective tissue that is often arranged in haphazard fascicles. (medscape.com)
  • Giant cell fibroma is the oral counterpart of fibrous papule of the nose . (medscape.com)
  • The term solitary fibrous tumor (SFT) is favored by soft-tissue pathologists to describe a rare, heterogeneous group of benign and malignant neoplasms along a morphologic continuum. (medscape.com)
  • Therefore, the TNM (Tumor size, Nodal involvement, Metastases) system used for most non-CNS tumors is not commonly employed in the evaluation of CNS neoplasms. (medscape.com)
  • Because neoplasms in the CNS have widely varying features, clinical courses, and prognoses, a robust and reliable grading system is essential for the proper evaluation of CNS tumors. (medscape.com)
  • abstract = "Here we report a case of a biphasic tumor consisting of pilocytic astrocytoma with anaplastic solitary fibrous tumor component in the pineal region. (elsevierpure.com)
  • Because the identification of key histopathologic features is highly sensitive to sampling, the new guidelines recommend using molecular signatures-which tend to be more diffuse and thus less sensitive to sampling-as a component in grading certain tumors and as a potential marker of clinical course and prognosis. (medscape.com)
  • Hepatic solitary fibrous tumor (HSFT) is a very rare benign liver tumor without well-defined findings on imaging. (utmb.edu)
  • These tumors have a high risk of recurring where they start and can also travel to liver, bone, lung, and other sites. (sarctrials.org)
  • The tumor can travel not only elsewhere in the abdominal or pelvic cavity where it starts, but it can also spread to liver, lung, or the space between the lungs (mediastinum). (sarctrials.org)
  • The majority of the tumor showed typical histologic features of pilocytic astrocytoma. (elsevierpure.com)
  • Sarcomatoid renal cell carcinoma (SRCC) is currently defined in the 2004 World Health Organization (WHO) classification of renal tumors as any histologic type of renal cell carcinoma (RCC) containing foci of high-grade malignant spindle cells. (medscape.com)
  • In cases in which the histologic subtype of the RCC component is not recognizable, the tumor is designated as unclassified RCC with sarcomatoid differentiation. (medscape.com)
  • [ 13 , 14 ] MRT usually arises in children younger than 3 years, and the occasional cases previously reported as adult MRT are now considered more likely to be RRCC in which rhabdoid components have overgrown the original histologic tumor type. (medscape.com)
  • Currently, the 2004 WHO classification of renal tumors recognizes this transformation as "sarcomatoid change" or "sarcomatoid features" arising within RCC, rather than as a separate histologic entity. (medscape.com)
  • [ 3 ] Consequently, grading each tumor requires an integrated analysis of histologic features and molecular signatures specific to that tumor type. (medscape.com)
  • Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics. (biocare.net)
  • Conclusions: Malignant solitary fibrous tumours may occur de novo or by transformation within benign or low-grade tumours and may be associated with p53 mutation. (fujita-hu.ac.jp)
  • Recurrent somatic fusions of the two genes, NGFI-A-binding protein 2 (NAB2) and STAT6, located at chromosomal region 12q13, have been identified in solitary fibrous tumors. (wikipedia.org)
  • NAB2-STAT6 fusion types account for clinicopathological variations in solitary fibrous tumors. (wikipedia.org)
  • The clinicopathological significance of NAB2-STAT6 gene fusions in 52 cases of intrathoracic solitary fibrous tumors. (nih.gov)
  • Another useful discovery was that the NAB2-STAT6 fusion is characteristic of solitary fibrous tumors. (nih.gov)
  • This led to development of a STAT6 antibody that is a reliable immunohistochemical marker for solitary fibrous tumors. (nih.gov)
  • Recently, STAT6 has received considerable attention in the area of tumor growth and metastasis. (biocare.net)
  • Scholars@Duke publication: Solitary fibrous tumor of the vulva resulting in spinal metastasis: A case report. (duke.edu)
  • We report a case of a vulvar solitary fibrous tumor, notable for extensive spinal metastasis. (duke.edu)
  • Intraorbital metastasis from solitary fibrous tumor. (nih.gov)
  • proposed the risk assessment score for predicting the development of metastasis in SFTs, which included the patient age, tumor size, mitotic activity, and the presence of necrosis. (axisneuromonitoring.com)
  • DSRCT is composed of small cells with round hyperchromatic nuclei and a dense fibrous or spindle cell stroma. (medscape.com)
  • A minor part of the tumor showed marked proliferation of short spindle cells around vessels. (elsevierpure.com)
  • Histopathology demonstrated well-circumscribed tumor (2 × 1 × 1 cm) as spindle-shaped subepithelial cells hyperplasia, in a "whorled" focal arrangement around collagen stroma and made a storiform structure, with monomorphic nuclei and eosinophilic cytoplasm. (thieme-connect.de)
  • If benign tumors are not removed, they have the potential to become cancerous. (naturalpedia.com)
  • Approximately 63% of patients will have a recurrence of their tumor, of which more than half will succumb to disease progression within two years. (wikipedia.org)
  • Long-term follow-up of these patients is required because of the risk of recurrence of these tumors and their uncertain biological behavior. (journalmc.org)
  • Radiation is occasionally used to try and prevent tumor recurrence, and chemotherapy is largely ineffective for this diagnosis. (sarctrials.org)
  • 1 The most frequent primary tumor types of anterior mediastinal masses are thymic tumors and lymphoma, with approximate proportions of 35% and 25% among mediastinal lesions, respectively. (allenpress.com)
  • Surgery and radiation of the primary tumor site provide the best chance for cure. (sarctrials.org)
  • Solitary fibrous tumors of the soft tissue may cause hypoglycemia. (naturalpedia.com)
  • Maldar AN, Chauhan PH, Lala M, Deshpande R. Late-onset non-islet cell tumor hypoglycemia associated with a pleural solitary fibrous tumor. (endocrinolrespract.org)
  • Solitary fibrous tumor associated with hypoglycemia: an example of the Doege-Potter syndrome. (ox.ac.uk)
  • Review of recent reported cases of NICTH identified widespread anatomic locations and varied pathologic diagnoses of tumors associated with paraneoplastic production of IGF-2 causing hypoglycemia. (medscape.com)
  • Some tumors contain only mature adipose tissue, whereas others contain multivacuolated lipoblasts and may have areas resembling atypical lipomatous tumor (ALT) ( Am J Surg Pathol 2011;35:1177 ). (pathologyoutlines.com)
  • Most periocular tumors formerly identified as soft tissue hemangiopericytomas, are currently recognized as solitary fibrous tumors, and probably hemangiopericytomas, solitary fibrous tumors, giant cell angiofibromas and fibrous histiocytomas are actually the same tumour, despite some morphologic and immuno labeling variations. (scitechnol.com)
  • RR CC was named for its morphologic resemblance to pediatric malignant rhabdoid tumor (MRT) of the kidney, which is a highly aggressive tumor characterized by cells that resemble rhabdomyoblasts and by genetic alterations involving chromosome 22, particularly the hSNF5/INI1 gene on 22q11.2. (medscape.com)
  • On cut sections, the tumors are tan-white and rubbery and have admixed, soft, yellow lipid rich foci ( Arch Pathol Lab Med 1999;123:941 , Am J Surg Pathol 1995;19:748 ). (pathologyoutlines.com)
  • Mature fat varies in amount but usually occupies approximately one quarter to three quarters of the area of tumor ( Am J Surg Pathol 1999;23:1201 ). (pathologyoutlines.com)
  • While some researchers have proposed that a SFT occupying at least 40% of the affected hemithorax be considered a "giant solitary fibrous tumor", no such "giant" variant has yet been recognized within the most widely used pleural tumor classification scheme. (wikipedia.org)
  • As such, CNS tumor classification heavily relies on accurate grading , which reflects the degree of abnormal behavior displayed by the tumor cells themselves. (medscape.com)
  • In 1979, the World Health Organization (WHO) codified its first set of guidelines on the classification and staging of CNS tumors. (medscape.com)
  • As an example, consider the classification of anaplastic tumors as elaborated in the WHO guidelines and Louis et al. (medscape.com)
  • Published in 2021, the fifth edition of the WHO Classification of Tumors of the CNS is the most recent version of the international standard for classifying brain and spinal cord tumors. (medscape.com)
  • Table 2 delineates the possible grades for each specific tumor type described in the 2021 WHO Classification of CNS Tumors. (medscape.com)
  • We present two clinical cases of patients aged 36 and 74 with an orbital solitary fibrous tumour (SFT). (scitechnol.com)
  • Huge primary epidural solitary fibrous tumors in the sacrum are a rare clinical entity. (axisneuromonitoring.com)
  • Giant pancreatic tumor with clinical characteristics of insulinoma but without common pathologic features. (rochester.edu)
  • [ 2 ] Grade was applied across tumor types, regardless of differences in the clinical course and molecular behavior of different anaplastic tumor entities. (medscape.com)
  • Although the term focal fibrous hyperplasia more accurately describes the clinical appearance and pathogenesis of this entity, it is not commonly used. (medscape.com)
  • Neurilemmomas arising from Schwann cells, rarely found in oral cavity, are characterized by solitary occurrence, slow growth and smooth surface with variable clinical aspects, depending on the nerve origin. (bvsalud.org)
  • At the chest tomography, a low-density mass with the presence of multiple vascularized septa, without evidence of tumor extension, without mediastinum nodes growth, neither metastatic lesions. (tgcd.org.tr)
  • These lesions are accessible through endoscopic/endobronchial ultrasound-guided or computed tomography-guided fine-needle aspiration cytology and represent a wide range of primary and metastatic tumors. (allenpress.com)
  • Tumors metastatic to mediastinal lymph nodes represent the most common mediastinal lesions and must be differentiated from primary lesions. (allenpress.com)
  • Mediastinal tumors/lesions are frequently encountered in daily cytopathology practice. (allenpress.com)
  • To provide an updated review on the fine-needle aspiration cytology of mediastinal tumors/lesions, with an emphasis on diagnostic challenges. (allenpress.com)
  • Data were gathered from a PubMed search of peer-reviewed literature on mediastinal tumors. (allenpress.com)
  • Some SFTs are associated with the paraneoplastic Doege-Potter syndrome, which is caused by tumor production of IGF-2. (wikipedia.org)
  • SFTs have also been known as hemangiopericytomas although this term has now been discontinued from WHO tumor classifications. (wikipedia.org)
  • [ 11 ] SFTs were initially incorrectly considered to be a localized form of fibrous mesothelioma. (medscape.com)
  • The postoperative pathology of the patient was reported as a pleuropulmonary solitary fibrous tumor. (tgcd.org.tr)
  • I discuss issues pertaining to the practice of neuropathology -- including nervous system tumors, neuroanatomy, neurodegenerative disease, muscle and nerve disorders, ophthalmologic pathology, neuro trivia, neuropathology gossip, job listings and anything else that might be of interest to a blue-collar neuropathologist. (blogspot.com)
  • These rare tumors can develop in any part of the body. (naturalpedia.com)
  • Other parts of the body where these rare tumors can form include the spinal cord, dura, head and neck, arms and legs, abdominal parenchymal organs, retroperitoneum, peritoneum, and pelvic organs. (naturalpedia.com)
  • It is one of the rare tumors with features of both sarcoma and melanoma, including the ability to travel to lymph nodes (typical of melanoma) and to lung (more common for sarcomas). (sarctrials.org)
  • Why and how it is replacing past approaches in the management of solid tumors is the subject of this two-part overview. (cancernetwork.com)
  • The situation with solid tumors is considerably more complex, and the evolution of targeted therapies for these cancers is still in its infancy. (cancernetwork.com)
  • At present, and for some years to come, the treatment of most solid tumors will continue to rely on a patchwork of empirically derived and newly introduced molecularly targeted agents. (cancernetwork.com)
  • The use of names that include mesothelioma for this tumor is discouraged because of potential confusion with diffuse malignant mesothelioma, a much more serious disease. (wikipedia.org)
  • A single-center study by DeVito et al found that malignant SFT, as compared with benign SFT, was associated with larger tumors, elevated mitotic counts, the presence of metastases at diagnosis, and more extensive use of chemotherapy and RT. (medscape.com)
  • Giant solitary fibrous tumor of the diaphragm: a case report and review of literature. (nih.gov)
  • Giant intrapericardial solitary fibrous tumor. (nih.gov)
  • Initial differentials involved more common masses in the sacral area, such as chordoma, chondrosarcoma, and giant cell tumor. (axisneuromonitoring.com)
  • The World Health Organization (2020) classified SFT as a specific type of tumor in the category of malignant fibroblastic and myofibroblastic tumors. (wikipedia.org)
  • This tumor typically spreads via hematogenous dissemination, primarily to the lungs, but rarely spreads via the lymphatics. (medscape.com)
  • This tumor typically arises in the skin and must be excised by an appropriate expert, as less extensive resections often end in failure. (sarctrials.org)
  • Sarcoma is a rare type of cancer and typically produces malignant tumors derived from the connective tissue. (curesarcoma.org)
  • Solitary fibrous tumors were previously known as localized fibrous mesotheliomas. (naturalpedia.com)
  • [ 7 ] Tumors with pure sarcomatoid morphology due to overgrowth of the RCC components are classified as SRCC if evidence of epithelial differentiation can be demonstrated through immunohistochemical or ultrastructural analysis. (medscape.com)
  • For example, the term epulis fissuratum refers to epithelial and fibrous hyperplasia specifically related to, and the result of, trauma from the border of a removable denture. (medscape.com)
  • This type of tumor affects men and women equally. (medlineplus.gov)
  • About one half of the people with this type of tumor do not show any symptoms. (medlineplus.gov)
  • Many of these sarcomas have some (but not all) features in common with their bone-tumor equivalents, and each has unique characteristics that must be considered in their treatment. (sarctrials.org)
  • 4 mitoses/10 high-power fields [HPF]) lesions characterized by cytologic atypia, tumor necrosis, or infiltrative margins. (medscape.com)