• NKCC2
  • As urine moves towards the more superficial portion of the thick ascending limb, NKCC2 is the major transport protein by which sodium is reabsorbed from the urine. (wikipedia.org)
  • transporters
  • As long as NKCC1 transporters are predominantely active, internal chloride concentrations in neurons is raised in comparison with mature chloride concentrations, which is important for GABA and glycine responses, as respective ligand-gated anion channels are permeable to chloride. (wikipedia.org)
  • depletion
  • Nevertheless, they can be associated with low sodium levels, volume depletion, and low blood pressure, among other adverse effects. (wikipedia.org)
  • extracellular
  • Amino acids and sugars are taken up from sea water in the presence of extracellular sodium and is driven by the NA+/K+-ATPase pump. (wikipedia.org)