Preservative0.02Solid sodium azideHydrazoicConcentration0.09ReagentHazardAqueous solutionNaN3Reacts violentlyConcentrationsInorganic compoundReaction0.01ExposureHazardsChlorideMixed with water or an acidToxicAirbagPoisonousDetonatorsNitrogen gasExplosionAntibodyOrganicNitriteSilicatesExplosivesAirbagsAntibacterialSaltsMutagenicIonsCentersLaboratoryCarefulSolutionRapidlyTraitsDrainGeneticFume hoodChemicalsPreparationAnalyticalPharmaceuticalSolutionsAvoidWaterDustLiquidStoreStandardSkinProductsControl
Preservative5
- Sodium azide is a useful probe reagent, and an antibacterial preservative for biochemical solutions. (wikipedia.org)
- Sodium azide is used as a chemical preservative in hospitals and laboratories. (cdc.gov)
- Sodium Azide is a versatile compound that can be used in dilute solutions as a preservative of biological samples and stock solutions. (teknova.com)
- Supplied as a liquid containing 15 mM sodium azide as preservative. (sigmaaldrich.com)
- Each Standard contains 0.05% sodium azide as preservative and 0.85% w/v NaCl. (sigmaaldrich.com)
0.021
- Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide. (antibodies-online.com)
Solid sodium azide3
- Ingestion is an important route of exposure to solid sodium azide. (cdc.gov)
- Due to the hazards associated with solid sodium azide, buying dilute solutions of 5% or less sodium azide is recommended. (illinois.edu)
- Sweep up spills of solid sodium azide carefully, and try to avoid dust formation. (illinois.edu)
Hydrazoic3
- Sodium azide rapidly hydrolyzes in water and acids, forming hydrazoic acid (HN 3 ), a highly toxic and volatile liquid solution that poses a serious inhalation hazard. (illinois.edu)
- Azides or hydrazoic acids (HN 3 ) are extremely lethal when inhaled or consumed. (news-medical.net)
- Sodium azide when distilled with 50% sulphuric acid yields hydrazoic acid. (sciencemadness.org)
Concentration4
- A nonlinear decline in mutagenic efficiency was observed with increasing concentration and dose of sodium azide. (ftstjournal.com)
- Best growth recorded in most of the morphological and yield traits evaluated was at 0.5mM concentration of sodium azide concentration. (ftstjournal.com)
- In order to overcome the influence of such ingredients, a transfer solution is used for rinsing an anion pre-concentration column for 6 minutes after pre-concentrating the azide in the column but before the chromatographic separation step. (news-medical.net)
- The pre-concentration column holds back the azide anions, while the transfer solution composed of 70% methanol and 30% ultrapure water removes the interfering pharmaceutical matrix. (news-medical.net)
0.091
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). (biolegend.com)
Reagent1
- Sodium azide is the reagent of choice for the production of primary amines, isocyanates, and several heterocyclic compounds and is widely used in the synthesis of a number of pharmaceuticals, including Avapro, Diovan, and Tamiflu. (acs.org)
Hazard2
- An electronic controller detonates this mixture during an automobile crash: 2 NaN3 → 2 Na + 3 N2 The same reaction occurs upon heating the salt to approximately 300 °C. The sodium that is formed is a potential hazard alone and, in automobile airbags, it is converted by reaction with other ingredients, such as potassium nitrate and silica. (wikipedia.org)
- Due to its explosion hazard, sodium azide is of only limited value in industrial-scale organic chemistry. (wikipedia.org)
Aqueous solution1
- Sodium azide can also react with the chloride salts of certain alkaline earth metals in aqueous solution, such as barium chloride or strontium chloride to respectively produce barium azide and strontium azide, which are also relatively sensitive primarily explosive materials. (wikipedia.org)
NaN34
- Sodium azide is an inorganic compound with the formula NaN3. (wikipedia.org)
- The sodium amide is subsequently combined with nitrous oxide: 2 NaNH2 + N2O → NaN3 + NaOH + NH3 These reactions are the basis of the industrial route, which produced about 250 tons per year in 2004, with production increasing due to the increased use of airbags. (wikipedia.org)
- This method is suited for laboratory preparation of sodium azide: 2 NaNO2 + 2 C2H5OH + H2SO4 → 2 C2H5ONO + Na2SO4 + 2 H2O C2H5ONO + N2H4·H2O + NaOH → NaN3 + C2H5OH + 3 H2O Alternatively the salt can be obtained by the reaction of sodium nitrate with sodium amide. (wikipedia.org)
- 2 NaN3 + 2 HNO2 → 3 N2 + 2 NO + 2 NaOH Older airbag formulations contained mixtures of oxidizers and sodium azide and other agents including ignitors and accelerants. (wikipedia.org)
Reacts violently1
- Sodium azide reacts violently with many common laboratory organic compounds and metals. (k-state.edu)
Concentrations4
- Seeds of Helianthus annuus cultivars Giza 1 and 102 were soaked in sodium azide solutions with the concentrations of 0, 100, 200, 300, 400 and 500 ppm for 4 h. (scialert.net)
- The two genotypes Giza 1 and 102 produced a wide range of response to sodium azide concentrations by the studied traits. (scialert.net)
- The trace concentrations of toxic azides up to the sub-ppb range in pharmaceutical formulations can be precisely detected using isocratic IC method equipped with the Metrohm Inline Matrix Elimination and suppressed conductivity detection. (news-medical.net)
- In surveys, blood haemoglobin concentrations are typically measured using the direct cyanmethemoglobin method in a laboratory or with a portable, battery-operated, haemoglobin photometer in the field that uses the azide-methaemoglobin method. (who.int)
Inorganic compound1
- Sodium Azide (NaN 3 ) is an inorganic compound commonly used as the gas forming agent in airbag systems. (k-state.edu)
Reaction5
- In the first step, ammonia is converted to sodium amide by metallic sodium: 2 Na + 2 NH3 → 2 NaNH2 + H2 It is a redox reaction in which metallic sodium gives an electron to a proton of ammonia which is reduced in hydrogen gas. (wikipedia.org)
- The azide functional group can thereafter be converted to an amine by reduction with either SnCl2 in ethanol or lithium aluminium hydride or a tertiary phosphine, such as triphenylphosphine in the Staudinger reaction, with Raney nickel or with hydrogen sulfide in pyridine. (wikipedia.org)
- Lead and silver azide can be made via double displacement reaction with sodium azide and their respective nitrate (most commonly) or acetate salts. (wikipedia.org)
- Reaction with lead or copper pipes can build up highly explosive azide salts. (illinois.edu)
- The reaction in the microcuvette is a modified azide-methaemoglobinn reaction. (who.int)
0.011
- On the protocol CLARITY immuno that the sample can be stored in PBST (with 0.01% (w / v) sodium azide) at 4 ° C for up to a week, but azide and fluorescent antibodies are incompatible or'm wrong. (claritytechniques.org)
Exposure5
- Persons who work on automobiles regularly are at an increased risk of exposure to sodium azide, which is used as a propellant in airbags. (cdc.gov)
- Exposure to sodium azide can be fatal. (cdc.gov)
- Sodium azide exposure can result in headache, respiratory distress, and diarrhea. (k-state.edu)
- The seriousness of poisoning caused by sodium azide depends on the amount, route, and length of time of exposure, as well as the age and preexisting medical condition of the person exposed. (cdc.gov)
- Moving to an area with fresh air is a good way to reduce the possibility of death from exposure to sodium azide. (cdc.gov)
Hazards1
- Two recent articles refer to the hazards of working with sodium azide (NaN 3 ) ( C&EN, Jan. 11, page 4 , and Nov. 9, 2009, page 8 ). (acs.org)
Chloride2
- Mixing sodium azide solutions with heavy metal salts including mercuric chloride can lead to explosions. (illinois.edu)
- We confirmed that bacteria in the VBNC state were resistant to all tested antibiotics (ampicillin, imipenem, ciprofloxacin, and gentamicin) and additionally insensitive to disinfectants (benzalkonium chloride and trioctylmethylammonium chloride) and preservatives (bronopol and sodium azide). (frontiersin.org)
Mixed with water or an acid1
- When it is mixed with water or an acid, sodium azide changes rapidly to a toxic gas with a pungent (sharp) odor. (cdc.gov)
Toxic6
- Organic azides will react with acids to form the highly toxic hydroazoic acid. (k-state.edu)
- In one case, sodium azide was poured into a drain, where it exploded and the toxic gas was inhaled (breathed in). (cdc.gov)
- An explosion involving sodium azide may cause burn injury as well as expose people to the toxic gas, hydrozoic acid. (cdc.gov)
- Breathing the gas that is formed from sodium azide causes the most harm, but ingesting (swallowing) sodium azide can be toxic as well. (cdc.gov)
- Sodium azide is highly toxic. (illinois.edu)
- Sodium azide for example may be mutagenic (and highly toxic), but it has not been shown to be carcinogenic. (roadlesstraveledstore.com)
Airbag3
- An electrical charge triggered by automobile impact causes sodium azide to explode and convert to nitrogen gas inside the airbag. (cdc.gov)
- I have also considered the possibility to find an old airbag and 'extract' sodium azide from it. (sciencemadness.org)
- I once found a homepage with pictures and everything of an airbag being opened and the sodium azide removed. (sciencemadness.org)
Poisonous2
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. (antibodies-online.com)
- Keep in mind that the azides are more poisonous even than cyanides! (sciencemadness.org)
Detonators2
- Sodium azide is a versatile precursor to other inorganic azide compounds, e.g., lead azide and silver azide, which are used in detonators as primary explosives. (wikipedia.org)
- Sodium azide is also used in detonators and other explosives. (cdc.gov)
Nitrogen gas1
- The sodium azide was present as small pellets, which was dissolved in water to remove insoluble additives such as iron oxide and/or silicates which are added to react with the metallic sodium that is formed when the azide breaks down (into nitrogen gas and sodium metal vapour of course). (sciencemadness.org)
Explosion1
- Even dilute solutions can accumulate enough azide salts over time to cause a serious explosion. (illinois.edu)
Antibody1
- This antibody contains sodium azide. (biolegend.com)
Organic3
- In the laboratory, it is used in organic synthesis to introduce the azide functional group by displacement of halides. (wikipedia.org)
- Do not allow organic azide waste to come in contact with acids. (k-state.edu)
- It reacts with halogenated organics (e.g., dichloromethane), forming explosive organic azides. (illinois.edu)
Nitrite2
- Curtius and Thiele developed another production process, where a nitrite ester is converted to sodium azide using hydrazine. (wikipedia.org)
- Sodium nitrite converts haemoglobin to methaemoglobin which, together with sodium azide, gives azidemethaemoglobin. (who.int)
Silicates1
- In the latter case, innocuous sodium silicates are generated. (wikipedia.org)
Explosives2
- While sodium azide is still used in evacuation slides on modern aircraft, newer-generation automotive air bags contain less sensitive explosives such as nitroguanidine or guanidine nitrate. (wikipedia.org)
- When sodium azide or its solutions come into contact with metal surfaces such as lead, copper, zinc, silver, or brass, heavy metal azides, which are highly shock-sensitive explosives, are formed. (illinois.edu)
Airbags1
- Sodium azide is best known as the chemical found in automobile airbags. (cdc.gov)
Antibacterial1
- The researchers report that saliva samples were first stabilized by adding thioflavin S as an antiaggregation agent and sodium azide as an antibacterial agent. (medscape.com)
Salts1
- Clearly label all equipment and instruments that come into contact with sodium azide, and thoroughly flush them with water to avoid the build-up of azide salts. (illinois.edu)
Mutagenic2
- An evaluation of the mutagenic efficiency and mutagenic effectiveness of fast neutron and sodium azide to induce genetic variability and beneficial mutation on Sesamumindicumwas carried out.The seeds of sesame were subjected to four treatments (0.5mM, 1.0mM, 1.5mM and 2.0mM) of sodium azide. (ftstjournal.com)
- The mutagenic effectiveness and efficiency of sodium azide in sesame was 2.27% and 0.72%, respectively. (ftstjournal.com)
Ions2
- Spectrophotometry, gas chromatography, and capillary electrophoresis are some of the widely used analytical techniques for determination of azide ions. (news-medical.net)
- The precise IC method was used for the analysis of azide ions in Irbesartan to demonstrate its applicability in the determination of trace amounts of inorganic impurities in pharmaceuticals. (news-medical.net)
Centers1
- Each azide is linked to six Na+ centers, with three Na-N bonds to each terminal nitrogen center. (wikipedia.org)
Laboratory1
- Wear standard laboratory attire i.e., closed-toe shoes, long pants, a lab coat, eye protection, and nitrile gloves when handling sodium azide powder or solution. (illinois.edu)
Careful2
- These azides can be recovered from solution through careful desiccation. (wikipedia.org)
- Be careful servicing metal parts that have come into contact with sodium azide. (illinois.edu)
Solution1
- Sodium azide in solution is rapidly absorbed through the skin. (illinois.edu)
Rapidly2
- Sodium azide is a rapidly acting, potentially deadly chemical that exists as an odorless white solid. (cdc.gov)
- If you think you may have been exposed to sodium azide, you should remove your clothing, rapidly wash your entire body with soap and water, and get medical care as quickly as possible. (cdc.gov)
Traits1
- Upon comparism with the control, sodium azide induced beneficial variabilities on the agronomic traits evaluated at M2generation. (ftstjournal.com)
Drain1
- Under no circumstances should you pour sodium azide solutions down the drain. (illinois.edu)
Genetic1
- This research aimed to study the effect of sodium azide on the growth of sunflower and induction of genetic variation in the vegetative and flowering growth as new patterns. (scialert.net)
Fume hood1
- Wipe bench and walls of fume hood with soap and water after working with azides. (k-state.edu)
Chemicals2
- The azide ion is an extremely useful nucleophile that has been used safely for many years at companies such as AMPAC Fine Chemicals (AFC, formerly Aerojet Fine Chemicals). (acs.org)
- As with many chemicals deemed hazardous, sodium azide can be safely handled and used in large-scale chemical processes as long as certain precautions are taken (see, for example, Chemical Market Reporter, Jan. 3, 2005, page 267). (acs.org)
Preparation2
- It is used for the preparation of other azide compounds. (wikipedia.org)
- For those of you who still want this book, the preparation of the azides section is on the roguesci FTP. (sciencemadness.org)
Analytical1
- Typical problems caused by the interfering excipients, such as nitrate anions, are eliminated by the analytical setup through the generation of a well-defined azide peak. (news-medical.net)
Pharmaceutical2
- Variety of tetrazole derivatives, including antihypertensive pharmaceutical agent Irbesartan, are produced using alkali metal azides (MeN 3 ). (news-medical.net)
- The presence of interfering Irbesartan components in pharmaceutical products increases the complexity of ultratrace azide analysis. (news-medical.net)
Solutions1
- In the past merthiolate and chlorobutanol were also used as an alternative to azide for preservation of biochemical solutions. (wikipedia.org)
Avoid2
- Avoid all contact between sodium azide and metals if possible. (k-state.edu)
- If you are near a release of sodium azide, emergency coordinators may tell you to either evacuate the area or to " shelter in place " inside a building to avoid being exposed to the chemical. (cdc.gov)
Water3
- Water: Sodium azide can be used to contaminate water. (cdc.gov)
- Following release of sodium azide into water, you could be exposed to sodium azide by drinking the contaminated water. (cdc.gov)
- The bit I have got is if you pass N2O over the melted sodamide you get sodium azide and water, the water should be blown away. (sciencemadness.org)
Dust1
- Following release of sodium azide into the air, you could be exposed by breathing in the dust or the gas that is formed. (cdc.gov)
Liquid1
- Sodium easily dissolves in liquid ammonia to produce hydrated electrons responsible for the blue color of the resulting liquid. (wikipedia.org)
Store1
- Store sodium azide in a cool, dry area away from heat and open flames. (illinois.edu)
Standard1
- ACS's Standard Package lets you stay up to date with C&EN, stay active in ACS, and save. (acs.org)
Skin2
Products2
Control2
- Sodium azide is used in agriculture (farming) for pest control. (cdc.gov)
- Therefore, industries that use or manufacture azide need to implement stringent control measures. (news-medical.net)