Loading...
  • stent
  • A sirolimus eluting coronary stent is marketed by Cordis, a division of Johnson & Johnson , under the tradename Cypher . (wikidoc.org)
  • BRIDGEWATER, N.J., June 15, 2011 /PRNewswire-FirstCall/ -- Cordis Corporation, a worldwide leader in the development and manufacture of interventional vascular technology, today announced it will no longer pursue the development of the NEVO™ Sirolimus-Eluting Coronary Stent in order to focus on other cardiovascular therapies where significant patient need exists. (mdtmag.com)
  • Bioengineered, Sirolimus-Eluting Stent Found 'Safe,' and 'Effective. (wikipedia.org)
  • drug
  • Treatment with sirolimus must be monitored because the range in which the drug is effective but not toxic is very narrow. (labcorp.com)
  • Because of the long time that it takes to clear the drug from the body (its long half-life), the sirolimus concentration may take some time to reach a steady state (equilibrium) in the blood. (labcorp.com)
  • The current research is being done to determine the safety and the usefulness of treatment of non-infectious uveitis using a drug called sirolimus. (clinicaltrials.gov)
  • Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Sirolimus, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions. (internationaldrugmart.com)
  • This made sirolimus the first drug approved to treat this disease. (wikipedia.org)
  • calcineurin
  • The chief advantage sirolimus has over calcineurin inhibitors is that it is not toxic to kidneys. (wikidoc.org)
  • Sirolimus can also be used alone or in conjunction with calcineurin inhibitors and/or mycophenolate mofetil , to provide steroid-free immunosuppression regimes. (wikidoc.org)
  • The chief advantage sirolimus has over calcineurin inhibitors is its low toxicity toward kidneys. (wikipedia.org)
  • evaluate
  • Other tests may also be periodically ordered to evaluate organ function and blood cell counts because sirolimus may decrease a person's platelet count, increase blood lipids, and, when taken long-term with other immunosuppressants, affect kidney function. (labcorp.com)
  • warn
  • However, on 7 October 2008, the FDA approved safety labeling revisions for sirolimus to warn of the risk for decreased renal function associated with its use. (wikipedia.org)
  • infection
  • Sirolimus can lower blood cells that help fight infection, and may cause you to produce too much of a certain type of white blood cell. (cigna.com)
  • lung
  • On May 28, 2015, the FDA approved sirolimus to treat lymphangioleiomyomatosis (LAM), a rare, progressive lung disease that primarily affects women of childbearing age. (wikipedia.org)
  • known
  • It is not known whether sirolimus passes into breast milk or if it could harm a nursing baby. (cigna.com)
  • An anti-rejection-type medication, sirolimus, helps to limit the overgrowth of normal cells while the artery heals which reduces the chance of re-blockage in the treated area known as restenosis, and reduces the chances that another procedure is required. (wikipedia.org)