• pyoverdine
  • Altogether, the data allow considering pyoverdine, the fluorescent pigment and siderophore, which characterizes these species, as a very powerful taxonomic marker. (springer.com)
  • Like most siderophores, pyoverdine is synthesized and secreted into the environment when the microorganism that produces it detects that intracellular iron concentrations have fallen below a preset threshold. (wikipedia.org)
  • Antibiotics Actinomycin Bacitracin Calcium dependent antibiotic Daptomycin Vancomycin Teixobactin Tyrocidine Gramicidin Zwittermicin A Antibiotic precursors ACV-Tripeptide Cytostatics Epothilone Bleomycin Immunosuppressants Ciclosporin (Cyclosporine A) Siderophores Pyoverdine Enterobactin Myxochelin A Pigments Indigoidine Toxins Microcystins and Nodularins, cyanotoxins from cyanobacteria. (wikipedia.org)
  • genes
  • Eisendle, M., Oberegger, H., Zadra, I. and Haas, H. (2003) The Siderophore System Is Essential for Viability of Aspergillus nidulans Functional Analysis of Two Genes Encoding L-Ornithine N5-Monooxygenase (sidA) and a Non-Ribosomal Peptide Synthetase (sidC). (scirp.org)
  • colonization
  • Mice immunized with the CTB-siderophore conjugate developed anti-siderophore antibodies in the gut mucosa, and whenmice were infected with the enteric pathogen Salmonella, they exhibited reduced intestinal colonization and reduced systemic dissemination of the pathogen. (universia.net)
  • Collectively, our results demonstrate that anti-siderophore antibodies inhibit Salmonella colonization. (universia.net)
  • Here, we have developed a novel quantitative metabolomic approach based on stable isotope dilution to compare the complement of siderophores produced by Escherichia coli strains associated with intestinal colonization or urinary tract disease. (plos.org)
  • enterobactin
  • Siderophores are amongst the strongest binders to Fe3+ known, with enterobactin being one of the strongest of these. (wikipedia.org)
  • While all strains produced enterobactin, strong preferential expression of the siderophores yersiniabactin and salmochelin was observed among urinary strains. (plos.org)
  • A linearized enterobactin siderophore was also identified as a product of strains with an active salmochelin gene cluster. (plos.org)
  • fungal
  • Combined with the absence of a sidA ortholog-and the fungal siderophore system in general-in mammals, these data demonstrate that the siderophore biosynthetic pathway represents a promising new target for the development of antifungal therapies. (rupress.org)
  • chelation therapy
  • Because of this property, they have attracted interest from medical science in metal chelation therapy, with the siderophore desferrioxamine B gaining widespread use in treatments for iron poisoning and thalassemia. (wikipedia.org)
  • deferoxamine, a naturally occurring siderophore produced by the actinobacter Streptomyces pilosus and was used initially as a chelation therapy agent. (wikipedia.org)
  • metabolites
  • Diffusion chamber experiments demonstrated that physical attachment or contact of soluble metabolites such as siderophores with the basaltic glass plays a pivotal role in this process. (ucsd.edu)
  • pathogens
  • Here, we report an immunization approach that targets siderophores, which are small molecules exported by enteric Gram-negative pathogens to acquire iron, an essential nutrient, in the host. (universia.net)
  • demonstrate
  • In live cells, however, siderophore ratios are maximized toward avaroferrin production, and we demonstrate that these siderophore ratios are the result of a regulation on substrate pool level, which may allow rapid evolutionary adaptation to environmental changes. (uni-konstanz.de)
  • ions
  • Siderophores usually form a stable, hexadentate, octahedral complex preferentially with Fe3+ compared to other naturally occurring abundant metal ions, although if there are fewer than six donor atoms water can also coordinate. (wikipedia.org)
  • transporter
  • In Candida albicans, the siderophore transporter Arn1p/Sit1p is required for epithelial invasion and penetration but not for systemic infection ( 13 ). (rupress.org)
  • production
  • Siderophore production and heterotrophic Fe(II) oxidation are discussed as potential mechanisms enhancing growth of P. stutzeri VS-10 on glass surfaces. (ucsd.edu)
  • Because uropathogenic E. coli are believed to reside in the gut microbiome prior to infection, we compared siderophore production between urinary and rectal isolates within individual patients with recurrent UTI. (plos.org)
  • involves
  • However, recent data indicate that A. fumigatus survival in human serum in vitro involves siderophore-mediated removal of iron from transferrin ( 17 ). (rupress.org)