• Diarrhea
  • There are several Shigella vaccine candidates in various stages of development that could reduce the incidence of dysentery in endemic countries, as well as in travelers suffering from traveler's diarrhea. (wikipedia.org)
  • bacterial
  • its S. typhimurium infection is caused by consumption of eggs or poultry that are not adequately cooked or by other interactive human-animal pathogens Escherichia coli O157:H7 enterohemorrhagic (EHEC) which can cause hemolytic-uremic syndrome Other common bacterial foodborne pathogens are: Bacillus cereus Escherichia coli, other virulence properties, such as enteroinvasive (EIEC), enteropathogenic (EPEC), enterotoxigenic (ETEC), enteroaggregative (EAEC or EAgEC) Listeria monocytogenes Shigella spp. (wikipedia.org)
  • antigens
  • Frequency and increase in antigen-specific serum IgG, IgA, and IgM antibody titers to S. sonnei LPS and invaplex-protein antigens. (clinicaltrials.gov)
  • Frequency and increase in antigen-specific fecal IgA antibody titer to S. sonnei LPS and invaplex-protein antigens (study day -1 or 0, study days 3,5,7,14, and 28). (clinicaltrials.gov)
  • Frequency and increase in antigen-specific IgG, IgA, and IgM antibody secreting cells (ASC) and antibody titers in lymphocyte supernatant (ALS) to S. sonnei LPS and invaplex-protein antigens (study days 0,7, and 9). (clinicaltrials.gov)
  • coli
  • The preparation of GMMA generated from S. sonnei -pSS ΔtolR ΔmsbB obtained after the second TFF step was subjected to electron microscopy analysis, revealing the presence of well-organized membrane vesicles with a diameter of about 30-60 nm (Fig. 3) which is consistent with the reported average size of 40±20 nm of outer membrane particles produced by E. coli tol-pal mutants . (nih.gov)
  • E. coli itself can also cause serious dysentery, but the difference in the genetic makeup between the E. coli and Shigella causes different medical conditions and symptoms. (wikipedia.org)
  • However, due to the medical conditions associated both with E. coli itself and with Shigella the current classification will not be changed, to avoid confusion in medical context. (wikipedia.org)
  • indole
  • Indole reactions are mixed, positive and negative, with the exception of S. sonnei, which is always indole negative. (wikipedia.org)
  • Rectal
  • citation needed] The most commonly observed signs associated with Shigella dysentery include colitis, malnutrition, rectal prolapse, tenesmus, reactive arthritis, and central nervous system problems. (wikipedia.org)
  • cultures
  • Yields of approximately 100 milligrams of membrane-associated proteins per liter of fermentation were obtained from cultures of S. sonnei ΔtolR ΔgalU at optical densities of 30-45 in a 5 L fermenter. (nih.gov)
  • symptoms
  • Infants and toddlers, the elderly, travelers, and ill people are susceptible to the most severe symptoms of S. sonnei disease. (wikipedia.org)
  • A confirmed case is defined as illness in a person with S. sonnei isolated from a clinical specimen, and a probable case is defined as clinically compatible symptoms in a person who was epidemiologically linked to a confirmed case. (cdc.gov)
  • cases
  • During May 1--August 31, 2005, a total of 148 confirmed cases of S. sonnei infection were reported in Fayette County ( Figure 2 ), which represented a 42-fold increase above the previous 5-year baseline. (cdc.gov)
  • In the beginning of April 2008 three cases of Shigella sonnei infection were identified among the Orthodox Jewish community of Antwerp, Belgium. (eurosurveillance.org)
  • severe
  • Most Shigella infection usually clears up without complications, but if left untreated or delay in diagnosis may lead to some serious complication such as dehydration (especially severe dehydration can lead to shock and death), seizure, hemolytic uremic syndrome (HUS), toxic megacolon, and reactive arthritis. (wikipedia.org)
  • If Shigella is suspected and it is not too severe, the doctor may recommend letting it run its course-usually less than a week. (wikipedia.org)
  • occur
  • Dehydration and seizures occur most often in children, although how Shigella causes these complications unknown. (wikipedia.org)
  • Study
  • The study assessed the potential impact of The Trivedi Effect® (biofield energy) onShigella sonnei for changes in antimicrobial sensitivity, biochemical study, and biotype number using MicroScan Walk-Away®system. (peerevaluation.org)
  • negative
  • Electron microscopy of Shigella sonnei ΔtolR ΔgalU GMMA.GMMA were isolated from the culture supernatant of S. sonnei -pSS ΔtolR ΔmsbB by TFF, prepared for negative staining, and viewed by electron microscopy revealing the presence of well-organized membrane vesicles with a diameter of about 30-60 nm. (nih.gov)
  • Shigella should also be urea hydrolysis negative. (wikipedia.org)
  • High
  • High yield production process for Shigella outer membrane particles. (nih.gov)
  • We developed a high yielding production process of genetically derived outer membrane particles from the human pathogen Shigella sonnei. (nih.gov)