• characterization
  • Recent deep sequencing-based characterization of the small RNA fraction (50-350 nt) of S. meliloti 2011 further confirmed the expression of Smr9C (here referred to as SmelC289), and mapped the 5'- and 3´-ends of the full-length transcript to positions 1,398,423 and 1,398,279, respectively, in the S. meliloti 1021 genome. (wikipedia.org)
  • Recent deep sequencing-based characterization of the small RNA fraction (50-350 nt) of S. meliloti further confirmed the expression of Smr35B (here referred to as SmelB053), and mapped the 5'- and 3´-ends of the molecule to the positions proposed earlier. (wikipedia.org)
  • Humans
  • The 5-HT1E receptor gene lacks polymorphisms amongst humans (few mutations), indicating a high degree of evolutionary conservation of genetic sequence, which suggests that the 5-HT1E receptor has an important physiological role in humans. (wikipedia.org)
  • residues
  • In addition to similarities shared by the acyltransferases, CPT II also contains a distinct insertion of 30 residues in the amino domain that forms a relatively hydrophobic protrusion composed of two alpha helices and a small anti-parallel beta sheet. (wikipedia.org)
  • peptides
  • The use of recombinant peptides based upon the repeated amino acid sequences of Plasmodium has been proposed for malaria vaccines. (ajtmh.org)
  • Sequences of peptides from a protein specifically immunoprecipitated by an antibody, KUL01, that recognises chicken macrophages, identified a homologue of the mammalian mannose receptor, MRC1, which we called MRC1L-B. Inspection of the genomic environment of the chicken gene revealed an array of five paralogous genes, MRC1L-A to MRC1L-E, located between conserved flanking genes found either side of the single MRC1 gene in mammals. (nih.gov)
  • genomes
  • The confirmed gene structures were used to locate orthologues of all five genes in the genomes of two other avian species and of the painted turtle, all with intact coding sequences. (nih.gov)
  • Subsequently, as more eukaryotes genomes were sequenced, it became clear that eukaryotes, in general, share homologs to the same set of seven Sm and eight LSm proteins. (wikipedia.org)
  • The manual inspection of the sequences found with the CM using Infernal allowed finding 26 true homolog sequences, all of them present as single chromosomal copies in the α-proteobacterial genomes. (wikipedia.org)
  • Genes
  • Transcripts of all five genes were detected in RNA from a macrophage cell line and other RNAs, whose sequences allowed the precise definition of spliced exons, confirming or correcting existing bioinformatic annotation. (nih.gov)
  • Receptors
  • Viruses and immune complexes (ICs) containing nucleic acids can access intracellular TLRs (TLR3, TLR7/8 and TLR9) after binding to Fc receptors and induce IFN-α production by activation of the IRFs. (wikipedia.org)
  • gene
  • In contrast, the expression of the methyljasmonate-responsive gene Thi2.1, a marker gene in plant defense responses, is not induced upon treatment with 12-hydroxyjasmonate indicating the existence of independent signaling pathways responding to jasmonic acid and 12-hydroxyjasmonic acid. (biomedsearch.com)
  • pXO2 encodes a five-gene operon (capBCADE) which synthesizes a poly-γ-D-glutamic acid (polyglutamate) capsule. (wikipedia.org)
  • The human IFNA gene family shares 70-80% amino acid sequence homology, and about 35% identity with IFNB. (wikipedia.org)
  • repetitive
  • The paucity of retrotransposons and the small genome size of A. thaliana support the hypothesis that most repetitive sequences have been lost from the genome and that mechanisms may exist to prevent amplification of extant element families. (harvard.edu)
  • bacteria
  • Enoyl-ACP reductase (ENR) catalyses the last reduction reaction in the fatty acid elongation cycle in bacteria and is a good antimicrobial target candidate. (nih.gov)
  • It is one of few bacteria known to synthesize a protein capsule (poly-D-gamma-glutamic acid). (wikipedia.org)
  • chromosome
  • The first member of this family (Smr9C) was found in a Sinorhizobium meliloti 1021 locus located in the chromosome (C). Further homology and structure conservation analysis have identified full-length Smr9C homologs in several nitrogen-fixing symbiotic rhizobia (i.e. (wikipedia.org)
  • placental
  • Phylogenetic analysis establishes that all LWS marsupial sequences form a distinct clade from the placental mammals that is subdivided into diprotodont and polyprotodont groups. (biomedsearch.com)
  • evolutionary
  • Amino acid differences in betaCOP may dictate functional divergence across species during the course of evolution, especially with regards to the evolutionary pressures on obligate intracellular parasites. (biomedsearch.com)
  • Phylogenetic analyses indicated that the A. thaliana sequences are more closely related to each other than to elements from other organisms, consistent with the vertical evolution of these sequences over most of their evolutionary history. (harvard.edu)
  • The pattern of similarities between sequences are consistent with the evolutionary history that was implied by phylogenetic analysis. (nih.gov)
  • encodes
  • mua-3 encodes a predicted 3,767 amino acid protein with a large extracellular domain, a single transmembrane helix, and a smaller cytoplasmic domain. (biomedsearch.com)
  • The first and second each contain 7 exons and encode the same full-length protein isoform a (786 amino acids, considered the major isoform), the third one contains 6 exons and encodes a shorter isoform b (732 amino acids) and the fourth one contains 5 exons and encodes the shortest isoform c (349 amino acids). (wikipedia.org)
  • genome
  • One sequence, Ta17, is located in the mitochondrial genome. (harvard.edu)
  • Link to the list of clones constituting the contig, the information on its mapping to the genome mapped to genome sequence and the list of top 10 hits in the results of homology search are provided. (biosciencedbc.jp)
  • The genome of Saccharomyces cerevisiae (Baker's Yeast) was sequenced in the mid-1990s, providing a rich resource for identifying homologs of these human proteins. (wikipedia.org)
  • enzyme
  • Despite of high sequence identity to previously reported Aspergillus oryzae and Penicilluim oxalicum β-N-acetylhexosaminidases, this enzyme tolerates significantly better substrate modification. (nih.gov)
  • Computational methods including homology modeling and molecular dynamics simulations were applied to shad light on the structure-activity relationship in the enzyme. (nih.gov)
  • relatedness
  • The predicted amino acid sequence for goldfish prominin shares all of the hallmark structural characteristics of the prominin family, however the relatedness assessed using the percent amino acid identity indicated that goldfish prominin cannot be placed into the current mammalian dichotomy of type 1 or 2. (biomedsearch.com)
  • genetic
  • Carnitine palmitoyltransferase II deficiency (CPT-II) is an autosomal recessively inherited genetic metabolic disorder characterized by an enzymatic defect that prevents long-chain fatty acids from being transported into the mitochondria for utilization as an energy source. (wikipedia.org)
  • Analysis
  • This report describes a prominin-like sequence and expression analysis of the prominin in the goldfish. (biomedsearch.com)
  • A bioinformatic analysis of betaCOP amino acid sequences was conducted for 49 eukaryotic species. (biomedsearch.com)
  • Primary sequence analysis revealed some variable regions able to influence difference in substrate affinity of hexosaminidases. (nih.gov)
  • Further homology and structure conservation analysis have identified full-length SmrB35 homologs in other legume symbionts (i.e. (wikipedia.org)
  • species
  • Isoform "a" of human CASS4 is considered the predominant species, and at 786 amino acids is the longest one. (wikipedia.org)
  • The rest of the sequences found with the model showed high E-values between (3.40e-12 and 2.62e-04) but lower bit-scores and are encoded by Brucella species (B. ovis, B. canis, B. abortus, B. microtis, and several biobars of B. melitensis), Ochrobactrum anthropi and the Mesorhizobum species loti, M. ciceri and M. BNC. (wikipedia.org)
  • signaling molecule
  • It is derived from the ubiquitously occurring jasmonic acid, an important signaling molecule mediating diverse developmental processes and plant defense responses. (biomedsearch.com)
  • motif
  • Light green shading indicates an overlapping potential di-aromatic endosome sorting motif in the MRC1 and MRC1L-A sequences. (nih.gov)
  • It also lacks a YDYVHL sequence at the N-terminal end of the FAT-like carboxy-terminal domain, even though this motif is conserved among the other three CAS family proteins and is an important binding site for the Src SH2 domain. (wikipedia.org)
  • suggests
  • A sequence comparison of piscivorin and other CRISP family proteins suggests that the Glu186 residue is the crucial site for the blocking of the calcium channels. (wikipedia.org)
  • organisms
  • in 2008 following in silico screening of databases describing expressed sequence tags from an evolutionarily diverse group of organisms, using the CAS-related proteins (p130Cas, NEDD9/HEF1 and EFS) mRNAs as templates. (wikipedia.org)
  • distinct
  • These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. (wikipedia.org)
  • viruses
  • IFNA and IFNB are produced by a wide range of cells such as macrophages, fibroblasts and endothelial cells, but plasmacytoid dendritic cells (pDCs) are considered the main producers of IFNA in response to RNA or DNA viruses or nucleic acid-containing immune complexes. (wikipedia.org)