Studies of monoamine oxidase and semicarbazide-sensitive amine oxidase. (erowid.org)
Geraniin, a tannin from P. urinaria , was reported to exhibit semicarbazide-sensitive amine oxidase inhibitory, antioxidant, and antihypertensive activities [ 4 ]. (ijpsonline.com)
Azodicarbonamide1
When used as endothermic blowing agent in the plastics industry, it is the preferred food grade, non-toxic alternative to exothermic blowing agents such as azo compounds (e.g. azodicarbonamide), hydrazine derivatives or semicarbazides. (jungbunzlauer.com)
Hydrazine2
The compound prepared by treating urea with hydrazine: OC(NH2)2 + N2H4 → OC(NH2)(N2H3) + NH3 A further reaction can occur to give carbohydrazide: OC(NH2)(N2H3) + N2H4 → OC(N2H3)2 + NH3 Semicarbazide is frequently reacted with aldehydes and ketones to produce semicarbazones via a condensation reaction. (wikipedia.org)
Biurea - another product of reaction of urea with hydrazine Carbazide - structurally related with the general formula (R2NNH)2C(O) Semicarbazide-cadmium therapy thiosemicarbazide CID 5196 from PubChem Jean-Pierre Schirmann, Paul Bourdauducq "Hydrazine" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2002. (wikipedia.org)
Derivatives1
Reactions of Carbamic Acid Derivatives to Give Semicarbazides 4. (elsevier.com)
Formula1
Semicarbazide is the chemical compound with the formula OC(NH2)(N2H3). (wikipedia.org)
Chemical1
The first chemical is semicarbazide (SEM), which has been linked to cancer of the lungs and blood vessels in mice, but not in rats, and the second chemical is urethane, which has been linked to cancer. (thehealthy.com)
Cells2
Semicarbazide products (semicarbazones and thiosemicarbazones) are known to have an activity of antiviral, antiinfective and antineoplastic through binding to copper or iron in cells. (wikipedia.org)
Optimisation and validation of a sensitive high-performance liquid chromatography assay for routine measurement of pyridoxal 5-phosphate in human plasma and red cells using pre-column semicarbazide derivatisation. (kcl.ac.uk)
Product1
Another breakdown product is semicarbazide, which poses "a negligible risk to humans" but was found to cause cancers of the lung and blood vessels in mice, CSPI said. (cnn.com)
Amine16
Additionally, AA toxicity is likely dependent on the enzyme semicarbazide-sensitive amine oxidase (SSAO), which is highly expressed in the aorta of rats and humans. (nih.gov)
6. Immunohistochemical study of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 in the hippocampal vasculature: pathological synergy of Alzheimer's disease and diabetes mellitus. (nih.gov)
9. The contribution of cerebral vascular semicarbazide-sensitive amine oxidase to cerebral amyloid angiopathy in Alzheimer's disease. (nih.gov)
10. Involvement of cerebrovascular semicarbazide-sensitive amine oxidase in the pathogenesis of Alzheimer's disease and vascular dementia. (nih.gov)
12. Soluble Vascular Adhesion Protein-1 Mediates Spermine Oxidation as Semicarbazide-Sensitive Amine Oxidase: Possible Role in Proliferative Diabetic Retinopathy. (nih.gov)
13. Origins of serum semicarbazide-sensitive amine oxidase. (nih.gov)
16. Inhibition of semicarbazide-sensitive amine oxidase reduces atherosclerosis in apolipoprotein E-deficient mice. (nih.gov)
17. Semicarbazide sensitive amine oxidase overexpression has dual consequences: insulin mimicry and diabetes-like complications. (nih.gov)
18. Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase. (nih.gov)
Geraniin, a tannin from P. urinaria , was reported to exhibit semicarbazide-sensitive amine oxidase inhibitory, antioxidant, and antihypertensive activities [ 4 ]. (ijpsonline.com)
AOC3 / VAP-1 is a member of the semicarbazide-sensitive amine oxidase family. (lsbio.com)
The Danish pharma has bought an exclusive worldwide licence from Japan's UBE for UD-014, a selective semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1) inhibitor small molecule. (pharmaphorum.com)
Exploring the binding mode of semicarbazide-sensitive amine oxidase/VAP-1: identification of novel substrates with insulin-like activity. (ub.es)
The Biological Implication of Semicarbazide-Sensitive Amine Oxidase (SSAO) Upregulation in Rat Systemic Inflammatory Response under Simulated Aerospace Environment. (dcgable.com)
Launch Human major amine oxidase (AOC3) also called vascular adhesion proteins-1 (VAP-1) or semicarbazide-sensitive amine oxidase (SSAO) continues to be investigated being a potential medication focus on of inflammatory illnesses due to its participation in leukocyte trafficking. (buyresearchchemicalss.net)
VAP-1 is one of the category of copper-containing amine oxidase/semicarbazide-sensitive amine oxidase (CAO/SSAO) enzymes. (buyresearchchemicalss.net)
Hydrochloride2
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Semicarbazide hydrochloride (563-41-7). (nih.gov)
Genetic Toxicity Evaluation of Semicarbazide hydrochloride in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)
Semicarbazones3
The compound prepared by treating urea with hydrazine: OC(NH2)2 + N2H4 → OC(NH2)(N2H3) + NH3 A further reaction can occur to give carbohydrazide: OC(NH2)(N2H3) + N2H4 → OC(N2H3)2 + NH3 Semicarbazide is frequently reacted with aldehydes and ketones to produce semicarbazones via a condensation reaction. (wikipedia.org)
Semicarbazide products (semicarbazones and thiosemicarbazones) are known to have an activity of antiviral, antiinfective and antineoplastic through binding to copper or iron in cells. (wikipedia.org)
Thus, the corresponding 2-amino-3-furancarboxaldehyde phenylhydrazones and semicarbazones were obtained upon treatment with phenylhydrazine and semicarbazide, respectively, whereas condensation with malononitrile yielded 2-substituted 6-aminofuro[2,3- b ]pyridine-5-carbonitriles. (enamine.net)
Carbazide1
Biurea - another product of reaction of urea with hydrazine Carbazide - structurally related with the general formula (R2NNH)2C(O) Semicarbazide-cadmium therapy thiosemicarbazide CID 5196 from PubChem Jean-Pierre Schirmann, Paul Bourdauducq "Hydrazine" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2002. (wikipedia.org)
Inhibitor1
The subcellular distribution of the protein was not altered in a catalytically inactive mutant form of the protein (Tyr471Phe) or in the presence of exogenous VAP-1 substrate (methylamine) or inhibitor (semicarbazide). (birmingham.ac.uk)
Conjugate1
The aldehyde function is often used to conjugate biopolymers to other molecules via reductive amination or adduct formation with hydroxylamines, hydrazines, and semicarbazides. (biosearchtech.com)
Inhibition1
They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, unlike EC 1.4.3.4, are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide. (cathdb.info)
Chemical compound1
Semicarbazide is the chemical compound with the formula OC(NH2)(N2H3). (wikipedia.org)
Toxicity2
Myocytes were protected by semicarbazide from allylamine toxicity. (cdc.gov)
Semicarbazide was not effective against acrolein toxicity. (cdc.gov)
Https1
nonassimilable illaudable visit begun https://gestalte.be/gestalte-aankoop-finasteride-met-mastercard an semicarbazide. (algec.org)
A series of new 1-Glycosyl-4-(2,4-dinitrophenyl) semicarbazides have been synthesized by the interaction of various Glycosyl isocyanates and 2,4-Dinitrophenyl hydrazine. (derpharmachemica.com)
Presence1
Myocytes exposed to 1mM allylamine in the presence of 0.1mM semicarbazide maintained normal ATP levels. (cdc.gov)