• Complementarity between Rous sarcoma virus (RSV) RNA and the in vitro-synthesized DNA of the virus-associated DNA polymerase. (wikidata.org)
  • Several chimeric murine retroviruses were constructed to test whether the gag sequence of Abelson murine leukemia virus (A-MuLV) could influence the in vitro specificity of two sarcoma-inducing oncogenes: src of Rous sarcoma virus and fps of Fujinami sarcoma virus. (duke.edu)
  • Livingston and Jackson also collaborated on work on the Rous sarcoma virus ( RSV ) at Lederle Laboratories. (ichacha.net)
  • In 1903 it was suggested for the first time that Rous sarcoma virus 1 and understood to be a retrovirus. (ichacha.net)
  • She continued her studies on the Rous sarcoma virus ( RSV ) that she had discovered in her postdoctorate work. (ichacha.net)
  • A recently published study evaluated the thermostability of murine retroviruses inocculated into factor concentrates, using a cell transformation assay (5). (cdc.gov)
  • The Glaxo researchers carried out their tests on murine retroviruses, not HIV itself, because Glaxo did not have the facilities required to test compounds against HIV [15]. (sufficientdescription.com)
  • The key tests carried out by the Glaxo researchers were in vitro "plaque reduction assays" using mouse cells and two different murine retroviruses, the Friend Leukemia Virus (FLV) and the Harvey Sarcoma Virus (HSV) [FC 113-14]. (sufficientdescription.com)
  • Infectivity and RNA patterns as functions of high- and low-dilution passage of murine sarcoma-leukemia virus: evidence for autointerference within an oncornavirus population. (wikidata.org)
  • This gene is the putative transforming gene of avian sarcoma virus 17. (ichacha.net)
  • V-CRK avian sarcoma virus CT10-homolog-like contains one SH2 domain and two SH3 domains. (ichacha.net)
  • Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. (edu.au)
  • Pathologic and virologic studies of tumors induced in mice by two strains of murine sarcoma vims. (microbiologyresearch.org)
  • Different cell culture characteristics of two strains of murine sarcoma virus. (microbiologyresearch.org)
  • Identification of the RAS gene family can be traced back to the 1970s, with the definition of the oncogenic sequences of the Kirsten and Harvey strains of murine sarcoma virus [ 1 ] . (oaepublish.com)
  • Does the Kaposi's sarcoma virus speed up progression of infection with HIV to AIDS? (ichacha.net)
  • Does the Kaposi's sarcoma virus suppress the immune system independently of the AIDS virus? (ichacha.net)
  • Does the Kaposi's sarcoma virus infect many people but cause disease in only a few? (ichacha.net)
  • The study was too limited in scope to prove that Kaposi's sarcoma virus causes myeloma. (ichacha.net)
  • The Columbia researchers said they began hunting for a Kaposi's sarcoma virus about 18 months ago. (ichacha.net)
  • The Los Angeles scientists found the Kaposi's sarcoma virus in two of eight patients with the gammopathy condition. (ichacha.net)
  • With the exception of one 31-year-old factor V-deficient individual with Kaposi's sarcoma (and without risk factors for AIDS other than his hemophilia), each patient had at least one opportunistic infection suggestive of an underlying cellular immune deficiency. (cdc.gov)
  • The factor V-deficient patient with Kaposi's sarcoma had not used factor VIII concentrate products but had used large volumes of plasma and factor IX concentrates. (cdc.gov)
  • Reactivation of the gammaherpesviruses Epstein-Barr virus (EBV), Kaposi's sarcoma-associated herpesvirus (KSHV) and murine gammaherpesvirus 68 (MHV68) from latently infected B cells has been linked to plasma cell differentiation. (prelekara.sk)
  • The first two Ras genes, HRAS and KRAS, were identified from studies of two cancer-causing viruses, the Harvey sarcoma virus and Kirsten sarcoma virus, by Edward M. Scolnick and colleagues at the National Institutes of Health (NIH). (wikipedia.org)
  • The genes encoding p21 proteins are now referred to as ras genes (from rat sarcoma genes). (cshmonographs.org)
  • In 2006 an alleged new virus, xenotropic murine leukemia virus XMRV, was thought to be involved in prostate cancer. (biomedcentral.com)
  • Here, we use murine gammaherpesvirus 68 (γHV68) to demonstrate that ABCs remain elevated long-term during latent infection and express IFNγ and TNF. (nature.com)
  • 4. UsherwoodEJ, StewartJP, RobertsonK, AllenDJ, NashAA (1996) Absence of splenic latency in murine gammaherpesvirus 68-infected B cell-deficient mice. (prelekara.sk)
  • RNA in mammalian sarcoma virus transformed nonproducer cells homologous to murine leukemia virus RNA. (wikidata.org)
  • During serial passage of mouse embryo fibroblasts in vitro it was found that an established line of cells was more susceptible to murine sarcoma virus transformation than early passages of the cells from which it was derived. (microbiologyresearch.org)
  • Characteristics of the in vitro assay of murine sarcoma virus (moloney) and virus-infected cells. (microbiologyresearch.org)
  • Morphological transformation of mouse embryo cells in vitro by murine sarcoma virus (harvey). (microbiologyresearch.org)
  • This recombinant virus behaved like the A-MuLV virus from which it was derived: it transformed both fibroblasts and lymphoid cells in vitro. (duke.edu)
  • Mesenchymal to epithelial transition driven by canine distemper virus infection of canine histiocytic sarcoma cells contributes to a reduced cell motility in vitro. (helmholtz-hzi.de)
  • Oxidative Stress in Canine Histiocytic Sarcoma Cells Induced by an Infection with Canine Distemper Virus Led to a Dysregulation of HIF-1α Downstream Pathway Resulting in a Reduced Expression of VEGF-B in vitro. (helmholtz-hzi.de)
  • These in vitro, and their expression in these human tumour virus. (who.int)
  • Comparison of murine sarcoma viruses in nonproducer and S + L - -transformed cells. (mssm.edu)
  • An explanation can be made in terms of the growth rates of the cells involved, although primary cells were more susceptible to murine sarcoma virus than would be expected from their rate of growth. (microbiologyresearch.org)
  • Non-dividing (amitotic) cells were not susceptible to murine sarcoma virus transformation. (microbiologyresearch.org)
  • Requirements for RNA and DNA synthesis in the transformation of mouse embryo cells by murine sarcoma virus (moloney). (microbiologyresearch.org)
  • The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells compared to wild-type AAV. (justia.com)
  • Epithelial features of 'nonproducer' balb/3t3 cells transformed by murine sarcoma virus. (jax.org)
  • 28. Rhim JS, Cho HY, Huebner RJ: Non-producer human cells induced by murine sarcoma virus. (achrinhibitor.com)
  • Cells carry the Ki-MSV genome but do not produce infectious virus particles or viral antigens. (cls.shop)
  • This study hypothesizes that a CDV infection of canine histiocytic sarcoma cells (DH82 cells) triggers the MET process leading to a decreased cellular motility. (helmholtz-hzi.de)
  • Persistent Morbillivirus Infection Leads to Altered Cortactin Distribution in Histiocytic Sarcoma Cells with Decreased Cellular Migration Capacity. (helmholtz-hzi.de)
  • Kelly, F. , Sambrook, J. (1974) Variants of Simian Virus 40-Transformed Mouse Cells Resistant to Cytochalasin-B. Cold Spring Harbor Symposia on Quantitative Biology, 39. (cshl.edu)
  • 1980). Therefore, it was concluded that the p21 gene was the oncogene of Ha-MSV and Ki-MSV (and other closely related viruses) and that this oncogene was derived from a proto-oncogenic form present in normal cells. (cshmonographs.org)
  • Diminished potential for B-lymphoid differentiation after murine leukemia virus infection in vivo and in EML hematopoietic progenitor cells. (harvard.edu)
  • We have previously shown that the MHV68 M2 protein is important for virus reactivation from B cells and, when expressed alone in primary murine B cells, can drive B cell differentiation towards a pre-plasma cell phenotype. (prelekara.sk)
  • In addition, expression of M2 in primary murine B cells leads to secretion of high levels of IL-10 along with enhanced proliferation and survival. (prelekara.sk)
  • In primary murine B cells, addition of cyclosporine (CsA) resulted in a significant decrease in M2-induced IL-10 levels as well as IRF4 expression, emphasizing the importance of the NFAT pathway in M2- mediated induction of IL-10. (prelekara.sk)
  • Murine Gammaherpesvirus M2 Protein Induction of IRF4 via the NFAT Pathway Leads to IL-10 Expression in B Cells. (prelekara.sk)
  • Miteva K, Haag M, Peng J, Savvatis K, Becher PM, Seifert M. Human cardiac-derived adherent proliferating cells reduce murine acute Coxsackievirus B3-induced myocarditis. (medscape.com)
  • Infection of stationary cultures with murine sarcoma virus (harvey). (microbiologyresearch.org)
  • Using a recombinant γHV68 that is cleared following acute infection, we show that ABCs persist in the absence of latent virus, though their expression of IFNγ and TNF is decreased. (nature.com)
  • AAV belongs to the Parvoviridae family and Dependovirus genus, whose members require co-infection with a helper virus such as adenovirus to promote replication, and AAV establishes a latent infection in the absence of a helper. (justia.com)
  • Intratumoral Canine Distemper Virus Infection Inhibits Tumor Growth by Modulation of the Tumor Microenvironment in a Murine Xenograft Model of Canine Histiocytic Sarcoma. (helmholtz-hzi.de)
  • Persistent Infection of a Canine Histiocytic Sarcoma Cell Line with Attenuated Canine Distemper Virus Expressing Vasostatin or Granulocyte-Macrophage Colony-Stimulating Factor. (helmholtz-hzi.de)
  • Moreover, The use of animals as surrogate rine host, can provide a platform for animal models for tumour viruses in hosts for the study of human tu- in vivo infection. (who.int)
  • Infectious causes of glomerulonephritis included streptococcal infections, human immunodeficiency virus (HIV) infection, and hepatitis viral infections, both hepatitis C (HCV) and hepatitis B (HBV). (medscape.com)
  • Conditional lethal mutants of adenovirus 2-simian virus 40 hybrids. (cshl.edu)
  • Production of altered cell foci in tissue culture by defective moloney sarcoma virus particles. (microbiologyresearch.org)
  • Effect of cytosine arabinoside on the replication of the Moloney sarcoma virus in 3T3 cell cultures. (microbiologyresearch.org)
  • Effect of pretreatment with immune serum on murine sarcoma virus (moloney) tumour induction and growth. (jax.org)
  • Various Moloney murine sarcoma virus (Mo-MuSV) isolates contain a cellular sequence, termed mos, which is responsible for the transforming ability of Mo-MuSV. (tmc.edu)
  • We find that mice without ABCs display defects in anti-viral IgG2a/c antibodies and are more susceptible to reactivation of γHV68 following virus challenges that typically do not break latency. (nature.com)
  • Based on the failure of conventional therapies, viral oncolysis might represent a promising alternative with canine distemper virus (CDV) as a possible candidate. (helmholtz-hzi.de)
  • these have been associated with the transmission of several known viral agents, including cytomegalovirus, hepatitis B virus, and the virus(es) of non-A, non-B hepatitis (9). (cdc.gov)
  • Aberrant Cellular Glycosylation May Increase the Ability of Influenza Viruses to Escape Host Immune Responses through Modification of the Viral Glycome. (cdc.gov)
  • A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance. (academicinfluence.com)
  • In: Cold Spring Harbor Symposia on Quantitative Biology XXXIX: Tumor Viruses, Cold Spring Harbor, N. Y. (cshl.edu)
  • In studies done at CDC, in cooperation with Cutter Laboratories, AIDS virus was added to factor VIII concentrate (virus titer 10((5))) and the factor was lyophilized and heated to 68 C (154.4 F). The residual virus titer was determined by an infectivity assay (6). (cdc.gov)
  • Development of a simple restriction fragment length polymorphism assay for subtyping of coxsackie B viruses. (medscape.com)
  • Feline Leukemia Virus Frequently Spills Over from Domestic Cats to North American Pumas. (harvard.edu)
  • Multiple Introductions of Domestic Cat Feline Leukemia Virus in Endangered Florida Panthers. (harvard.edu)
  • Epizootiology and management of feline leukemia virus in the Florida puma. (harvard.edu)
  • Genetic characterization of feline leukemia virus from Florida panthers. (harvard.edu)
  • An antigenic analysis of respiratory syncytial virus isolates by a plaque reduction neutralization test. (medscape.com)
  • Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. (edu.au)
  • One exception is hu- humanized SCID mice, the use of al oncogenic viruses that are strictly man T-cell lymphotropic virus type 1 surrogate hosts has not proven very species-specific, causing cancer in (HTLV-1): in addition to its ability to useful for defining tumour site con- humans only. (who.int)
  • In the context of previous findings, the data presented here provides insights into how M2 facilitates plasma cell differentiation and subsequent virus reactivation. (prelekara.sk)
  • For this reason, the infect humans, this virus can infect cordance between humans and ex- question about tumour site concor- several other species - including perimental animals. (who.int)
  • Animal models for human tumour mental animals is not easy to answer does induce adult T-cell leukaemia/ viruses that make use of animal virus- for these agents, because cancer bi- lymphoma (ATLL), albeit in monkeys es are scarce. (who.int)
  • With respect to viruses and cancer, the conclusive identification of the virus in cancer tissues and a significant odds ratio between cancer and non-cancer tissues, are of special importance. (biomedcentral.com)
  • For instance, mice are able to reconstitute most lymphomas in monkeys and humans woodchuck hepatitis virus induces major components of the human provides strong support for a direct hepatocellular carcinoma (HCC) haematolymphoid system including oncogenic role of EBV in vivo. (who.int)
  • Bifidobacterium as an oral delivery carrier of interleukin-12 for the treatment of Coxsackie virus B3-induced myocarditis in the Balb/c mice. (medscape.com)
  • A chicken sarcoma virus was found to carry mutated versions of the normal cellular Src gene. (ichacha.net)
  • Guidelines for Plaque-Reduction Neutralization Testing of Human Antibodies to Dengue Viruses. (medscape.com)
  • The mouse sarcoma virus 3611 contains a RAF kinase-related oncogene that enhances fibrosarcoma induction. (ichacha.net)
  • The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. (edu.au)
  • Not all researchers could find the virus, probably due to the low copy number. (biomedcentral.com)
  • The sera of 22 (42%) of the 52 hemophilia-associated AIDS patients have been tested for antibody to antigens of the AIDS virus using Western blot analysis (2). (cdc.gov)
  • Rates of AIDS virus antibody prevalence were 74% for factor VIII recipients and 39% for factor IX recipients (3,4). (cdc.gov)