Radionuclide imaging. Medical search. Frequent questions

The Trace 'n Treat Training network (Oct 2012 - Oct 2016) has fulfilled the very ambitious goal to train young researchers in the field of nuclear diagnostics and radionuclide therapy by bringing together disciplines that cover the entire health care cycle, from prevention to treatment. (europa.eu)
The research objectives of this project were: production of radionuclides with the most appropriate properties for molecular imaging and/or radionuclide therapy, their incorporation in newly designed molecular and supramolecular carriers and finally their pre-clinical evaluation and comparison. (europa.eu)
Diagnostic Imaging and Radionuclide Therapy. (avmi.net)
In this review, we will discuss the characteristics of molecular imaging, the novel imaging agent including targeted imaging agent and multifunctional imaging agent, as well as cite some examples of their application in molecular imaging and therapy. (hindawi.com)
A lot of preclinical and clinical studies have confirmed the feasibility of using radionuclide molecular imaging to detect tumor and predict response to therapy [ 12 , 13 ]. (hindawi.com)
For radiological diagnosis and radionuclide therapy, X-ray and gamma-ray imaging technologies are essential. (elsevierpure.com)
Radionuclide therapy is also rapidly developing with the use of these modalities. (elsevierpure.com)
We compared the efficacy of radionuclide therapy with 111 In-pentetreotide and 131 I-metaiodobenzylguanidine (MIBG) in 20 patients (group A) with the outcome of similar patients who could not be treated for nonmedical reasons (group B, n = 12). (snmjournals.org)
Radionuclide therapy was beneficial in 14 patients (73% of group A), with only 1 significant side effect. (snmjournals.org)
The overall Kaplan-Meier survival rate and cumulative progression-free and cumulative event-free survival rates during the first 15 mo were significantly higher in patients receiving radionuclide therapy ( P = 0.019, P = 0.024, and P = 0.019, respectively). (snmjournals.org)
Radionuclide therapy is feasible and safe and significantly defers the occurrence of fatal and nonfatal events in patients clinically uncontrolled by conventional therapy. (snmjournals.org)
Consequently, radionuclide therapy may be proposed to patients with uncontrolled disease after conventional therapy ( 5 , 11 ). (snmjournals.org)
In France, 131 I-MIBG can be used for radionuclide therapy. (snmjournals.org)
Octreotide labeling with 90 Y has recently been proposed for radionuclide therapy ( 12 - 16 ) but, to date, it is not commercially available in France. (snmjournals.org)
Because 111 In emits short-range electrons that can have significant biologic effects at a cellular level ( 17 - 19 ), radionuclide therapy with a high activity of 111 In-pentetreotide has been used in a few patients with GEP tumors ( 5 , 20 - 30 ). (snmjournals.org)
To our knowledge, there are no randomized controlled trials with radionuclide therapy in GEP tumors. (snmjournals.org)
We report the results of radionuclide therapy with either 111 In-pentetreotide or 131 I-MIBG in a population of patients with advanced-stage GEP tumors. (snmjournals.org)
Peptides can be labeled with various trivalent radiometals for imaging or targeted radionuclide-therapy applications. (nature.com)
High radiolabeling efficiency, preferably to high specific activity, and good stability of the radioimmunoconjugate are essential features for a successful immunoconjugate for imaging or therapy. (acs.org)
My research areas include quantitative abdominal imaging, pancreatitis, nuclear medicine and radionuclide therapy. (cincinnatichildrens.org)
This study considers the error distributions for time-integrated activity (TIA) of single-time-point (STP) methods for patient-specific dosimetry in radionuclide therapy. (lu.se)
The general case with the same pharmaceutical labelled with different radionuclides for imaging and therapy are considered for a mono-exponential time-activity curve. (lu.se)

Radionuclide imaging can expose patients to similar amounts of radiation than do comparable computed tomography (CT) studies. (msdmanuals.com)
There are five imaging modalities available for molecular imaging, including X-ray computed tomography imaging (CT), optical imaging (OI), radionuclide imaging (involving PET and SPECT), ultrasound (US) imaging and magnetic resonance imaging (MRI) [ 9 ]. (hindawi.com)
My research focuses on the development of novel radiotracers for positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging. (nottingham.ac.uk)
Cardiac imaging refers to minimally invasive imaging of the heart using ultrasound , magnetic resonance imaging (MRI), computed tomography (CT), or nuclear medicine (NM) imaging with PET or SPECT . (wikipedia.org)
Single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) with technetium-99m ( 99m Tc)-labelled radiotracers. (cadth.ca)
The guideline will provide a review of diagnostic modalities for patients with small bowel hemorrhage including VCE, endoscopic evaluation with push and/or deep enteroscopy, and radiographic modalities including cross-sectional imaging (computed tomography (CT) and magnetic resonance (MR)) enterography, angiography, and scintigraphy. (medscape.com)

SPECT, which uses a rotating camera system and tomographic reconstruction to produce a 3-dimensional image, is more common in the United States. (msdmanuals.com)
With multihead SPECT systems, imaging can often be completed in ≤ 10 minutes. (msdmanuals.com)
It is injected at peak stress and imaged with SPECT, followed 4 hours later by injection of half the original dose during rest and by repeat SPECT. (msdmanuals.com)
Extraosseous findings on bone scintigraphy using fusion SPECT/CT and correlative imaging. (tsnmjournals.org)
The paper "EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT/CT: 2015 revision" has restricted access. (cnr.it)
Radionuclide molecular imaging including PET and SPECT is the earliest and most mature molecular imaging technique. (hindawi.com)
PET and SPECT are whole body imaging techniques that use trace quantities of radioisotope-tagged bioactive molecules to probe biological function. (nottingham.ac.uk)
These cardiac techniques are otherwise referred to as echocardiography , Cardiac MRI , Cardiac CT , Cardiac PET and Cardiac SPECT including myocardial perfusion imaging . (wikipedia.org)

After acute myocardial infarction, myocardial perfusion imaging can help estimate prognosis because it can show extent of the perfusion abnormality due to acute myocardial infarction, extent of scarring due to previous infarcts, and residual peri-infarct or other areas of reversible ischemia. (msdmanuals.com)
All subjects underwent Technetium-99 m sestamibi single-photon emission computed tomographic imaging for the estimation of myocardial ischemia, expressed as Summed Stress Score (SSS). (springer.com)
1 The basic principle of radionuclide MPI is to administer a radiopharmaceutical intravenously and image blood flow to the heart muscle (myocardial perfusion), both at rest and under stress. (cadth.ca)
7 Viable myocardial cells take up the radionuclide tracer (either thallium isotope [ 201 TI] or isotope 99m Tc-labelled radiotracer) in proportion to blood flow. (cadth.ca)
Heart failure (see the images below) may be caused by myocardial failure but may also occur in the presence of near-normal cardiac function under conditions of high demand. (medscape.com)

Magnetic resonance imaging (MRI) of the liver can be useful in detecting and characterizing primary tumors, and MRI may be slightly more sensitive than CT scanning in detecting multiple intrahepatic recurrent lesions. (medscape.com)
Tumors are usually hypointense on T1-weighted images and hyperintense on T2-weighted images, with a fibrous central scar that remains hypointense on both T1- and T2-weighted images. (medscape.com)

Nuclear medicine and related radionuclide applications in developing countries : proceedings of an International Symposium on Nuclear Medicine and Related Medical Applications of Nuclear Techniques in Developing Countries, held in Vienna, 26-30 August 1985 / organized by the International Atomic Energy Agency, in co-operation with the World Health Organization. (who.int)
Abstract: Targeted radiotherapy is a form of nuclear medicine where a radionuclide, with desirable decay properties (such as the emission of an alpha, beta or Auger electron), is attached to a targeting vector that is highly specific for receptors that are over expressed on diseased cells. (wmis.org)
Automated radiosynthesis and preclinical in vivo evaluation of [18F]Fluoroethylpuromycin as a potential radiotracer for imaging protein synthesis with PET Nuclear Medicine and Biology. (nottingham.ac.uk)
Hypoxia imaging with [18F]HX4 PET in squamous cell head and neck cancers: a pilot study for integration into treatment planning Nuclear Medicine Communications. (nottingham.ac.uk)
Automated Radiosynthesis of GMP Quality [18F]HX4 for PET Imaging of Hypoxia Nuclear Medicine and Biology. (nottingham.ac.uk)
In Vitro and In Vivo Evaluations of a Hydrophilic 64Cu-Bis(thiosemicarbazonato)-glucose Conjugate for Hypoxia Imaging Journal of Nuclear Medicine. (nottingham.ac.uk)
I am a member of the Society for Pediatric Radiology (SPR), the Society of Nuclear Medicine and Molecular Imaging (SNMMI) and the North American Society for Gastroenterology, Hepatology and Nutrition (NASPGHAN). (cincinnatichildrens.org)

Radionuclide imaging with thallium or technetium is a noninvasive means to identify reversible cardiac ischemia in patients with cardiac cirrhosis in the setting of new or decompensated heart failure. (medscape.com)

Radionuclide tracer techniques in haematology / C. S. Bowring. (who.int)
We also verified that the 3D distribution of the At-211 tracer inside a mouse could be imaged using the pinhole mode. (elsevierpure.com)

Currently, a variety of serologic and cytogenetic tests, diagnostic imaging studies, and histopathologic techniques exist for the evaluation of a thyroid nodule. (medscape.com)
Diagnostic radiology : an Anglo-American textbook of imaging / edited by Ronald G. Grainger, David J. Allison. (who.int)
Rational use of diagnostic imaging in paediatrics : report of a WHO study group [meeting held in Geneva from 18 to 25 November 1985]. (who.int)
This Atlas will allow professionals interested in non-FDG PET/CT imaging to embrace the variety of oncological imaging by providing clinically relevant teaching files on the effectiveness and diagnostic quality of non-FDG-PET/CT imaging in routine applications. (iaea.org)
In addition, the imaging of Ga-67 and In-111, which are used in various diagnostic scenarios, was conducted. (elsevierpure.com)
Echocardiography is regularly utilized to diagnose, manage, and monitor patients with suspected or established heart ailments, making it a highly prevalent diagnostic imaging technique in cardiology due to its speed and efficiency. (wikipedia.org)

Radionuclide imaging uses a special detector (gamma camera) to create an image following injection of radioactive material. (msdmanuals.com)
Nevertheless, a limited number of radioactive tracers are imaged owing to the limitations of the imaging devices. (elsevierpure.com)
A small amount of a radioactive chemical (radionuclide) is injected into a vein or swallowed. (cancer.gov)

A great deal of research has brought about improved prostate imaging modalities. (baptisthealth.net)
Advances in imaging modalities in prostate cancer. (baptisthealth.net)
In this study, we developed a system that simultaneously realizes three modalities: Compton, pinhole, and PET imaging in 3D space using multiple hybrid Compton cameras. (elsevierpure.com)

Molecular imaging is an emerging field that integrates advanced imaging technology with cellular and molecular biology. (hindawi.com)
Molecular imaging is a rapidly developed multidiscipline which involves molecular biology, chemistry, computer, engineering, and medicine [ 1 ]. (hindawi.com)

It is the most commonly used imaging tool for diagnosing heart problems, as it allows non-invasive visualization of the heart and the blood flow through the heart, using a technique known as Doppler. (wikipedia.org)
As with nuclear imaging for other cardiac indications, the relative distribution of the radionuclide allows for visualization of blood flow through the heart and gives information regarding the functional capacity of the heart. (cadth.ca)

To develop a quantitative method for imaging osmotic blood-brain barrier disruption and to see if iopamidol could be safely given intravenously in conjunction with blood-brain barrier disruption. (ajnr.org)
Visual comparison of stress and delayed images can be supplemented by quantitative displays. (msdmanuals.com)
I am also working to develop and validate quantitative, non-invasive imaging biomarkers to reduce the need for invasive testing. (cincinnatichildrens.org)

Also may occur with other primary malignancies, which can cause confusion with the metastasis in whole body bone scan (WBBS) imaging. (tsnmjournals.org)
Tc-99m radionuclide scan was proven to be a useful tool, enabling distinction between the two processes. (tau.ac.il)
A radionuclide cystogram is a special imaging nuclear scan test. (mountsinai.org)
Breast cancer may be evaluated using the nuclear bone scan as an imaging modality. (bvsalud.org)

Imaging bone metastases in breast cancer: techniques and recommendations for diagnosis. (tsnmjournals.org)
This should facilitate the interpretation of images to support accurate diagnosis. (iaea.org)
Therefore, molecular imaging plays an important role in earlier detection, accurate diagnosis, and drug development and discovery [ 5 - 7 ]. (hindawi.com)
A physician may recommend cardiac imaging to support a diagnosis of a heart condition. (wikipedia.org)
Used with organs and regions for ultrasonic imaging and with diseases for ultrasonic diagnosis. (bvsalud.org)
Used for radionuclide imaging of any anatomical structure, or for the diagnosis of disease. (bvsalud.org)

Medical specialty professional organizations discourage the use of routine cardiac imaging during pre-operative assessment for patients about to undergo low or mid-risk non-cardiac surgery because the procedure carries risks and is unlikely to result in the change of a patient's management. (wikipedia.org)

abstract = "Tc-99m pertechnetate radionuclide scrotal scanning was performed on nine hospitalized boys with anaphylactoid purpura and acute scrotal tenderness. (tau.ac.il)

Results of search for 'su:{Radionuclide imaging. (who.int)

Before a radionuclide is ready for use in targeted radiotherapy applications it must first be produced and made available in a radiochemically pure form. (wmis.org)
Clinicians' Guides to Radionuclide Hybrid Imaging PET/CT in Radiotherapy Planning. (nottingham.ac.uk)

Did you mean topic:"abdomen - radionculides imaging" ? (nshealth.ca)

Two agents have been proposed for GEP tumor imaging: pentetreotide ([DTPA- d -Phe 1 ]octreotide, where DTPA is diethylenetriaminepentaacetic acid) ( 6 - 8 ) and metaiodobenzylguanidine (MIBG) ( 9 , 10 ). (snmjournals.org)
Brain Tumor Imaging and Treatment Effects. (lu.se)

METHODS Forty-five blood-brain barrier disruption procedures were imaged with CT and radionuclide scans. (ajnr.org)

With the use of the radionuclide gastric-emptying test and a new data processing method, the contraction characteristics of the stomach were analyzed. (nih.gov)

Contrast-enhanced CT is the preferred method to image disruption because it has better spatial resolution than radionuclide techniques. (ajnr.org)
however, these imaging techniques, though often invaluable, can be expensive and may prove unnecessary with a thorough physical examination and a solid understanding of the many pathologies that may lead to pain on the ulnar side of the wrist. (medscape.com)

Stress Testing In stress testing, the heart is monitored by electrocardiography (ECG) and often imaging studies during an induced episode of increased cardiac demand so that ischemic areas potentially at risk. (msdmanuals.com)
[1] Stress cardiac imaging is discouraged in the evaluation of patients without cardiac symptoms or in routine follow-ups. (wikipedia.org)
With the introduction of the matrix TEE probe, 3D TEE can collect real-time 3D images that provide a comprehensive view of the heart structures, leading to better understanding and decision making during cardiac procedures. (wikipedia.org)
7,8 Through sequential image acquisition, the gamma camera works with a computer to evaluate cardiac function and perfusion. (cadth.ca)
Body imaging may reveal evidence of cardiac cirrhosis, including hepatomegaly, hepatic congestion, IVC enlargement, and splenomegaly (see following images). (medscape.com)

Therapeutic drug or gene is incorporated into nanoparticles to construct multifunctional imaging agents which allow for theranostic applications. (hindawi.com)
In this webinar, I will discuss charged particle, neutron and photonuclear reactions used to produce therapeutic radionuclides of interest. (wmis.org)

A PET detector surrounding the subject is designed to detect the signal and convert the resulting electrical signal into sinograms that are finally rebuilt into tomographic images. (hindawi.com)

Nitroimidazole Conjugates of Bis(thiosemicarbazonato)64Cu(II) - Potential Combination Agents for the PET Imaging of Hypoxia Journal of Inorganic Biochemistry. (nottingham.ac.uk)

The imaging time with MRI examinations tends to be longer than with CT scanning or ultrasonography. (medscape.com)

Transesophageal echocardiography creates clearer images of the heart and surrounding blood vessels than traditional transthoracic echocardiography (TTE). (wikipedia.org)

The CDFs are used for determining 95% coverage intervals of the relative errors for different combinations of imaging time points, physical decay constants, and relative standard deviations of the biological decay constant. (lu.se)

The peptide is first conjugated to a chelating agent that is able to form stable complexes with the radionuclide of interest. (nature.com)

SPATIAL RESOLUTION in air for a specified radionuclide excluding the COLLIMATOR 3.19 INTRINSIC ENERGY SPECTRUM measured histogram of pulse heights for the DETECTOR HEAD without COLLIMATOR NOTE The pulse height should be expressed as corresponding energy. (findfreestandards.com)
Multi-modality medical imaging enables measurement of the three-dimensional spatial distribution of inhaled, radiolabelled aerosol within the human lung. (uaeu.ac.ae)

[5] TTE can visualize non-dilated coronary arteries and measure coronary artery flow using harmonic imaging, contrast agents, and high-frequency transducers. (wikipedia.org)

Development of novel theragnostic radiopharmaceuticals for the imaging and treatment of the poor prognosis childhood cancer neuroblastoma. (kcl.ac.uk)

PET is the molecular imaging modality most extensively used in current clinic routine. (hindawi.com)

Brill DR. Radionuclide imaging of nonneoplastic soft tissue disorders. (tsnmjournals.org)

L'interpretation collegiale etait effectuee apres acquisition et traitement des images obtenues au moyen d'une gamma camera. (bvsalud.org)

with a specified COLLIMATOR and ENERGY WINDOW , the ratio of the COUNT RATE of the DETECTOR HEAD to the ACTIVITY of a plane source of specific dimensions and containing a specified radionuclide placed perpendicular to and centred on the COLLIMATOR AXIS under specified conditions NOTE See also Figure 2. (findfreestandards.com)

Recent projects include development of new radiotracers for imaging bacterial infection, hypoxia imaging in cancer patients using 18 F-HX4 (OXYPET Trial), development of new fluorine-18 labelled molecules for protein synthesis imaging, and various early stage radiochemistry projects using fluorine-18, zirconium-89 and technetium-99m. (nottingham.ac.uk)
TEE is especially useful for patients with obesity or chronic obstructive pulmonary disease (COPD) who may have difficulty obtaining high-quality images using TTE. (wikipedia.org)
Who are the right patients for radionuclide imaging? (asnc.org)
Imaging findings and cognitive function in glioblastoma patients. (lu.se)
Given advances in small bowel imaging with video capsule endoscopy (VCE), deep enteroscopy, and radiographic imaging, the cause of bleeding in the small bowel can now be identified in most patients. (medscape.com)
The reason for this change in terminology is owing to the fact that the cause of bleeding can now be detected in the majority of patients given advances in small bowel imaging with video capsule endoscopy (VCE), deep enteroscopy, and radiographic imaging. (medscape.com)

In the planar images, radiotracer uptake at multiple sites was detected on the anterior side of the skull base and the posterior side of the vertex of the cranium. (tsnmjournals.org)

Furthermore, we will discuss the separation chemistry and quality control considerations that are required to realize these radionuclides for medical applications. (wmis.org)

Radiographic images may show cardiomegaly, pulmonary venous hypertension, interstitial or pulmonary edema, or pleural effusion. (medscape.com)

Experimental data regarding radiolabeling efficiencies of each immunoconjugate under increasingly dilute conditions, bifunctional chelator to antibody ratio determination, PET images for all radioimmunoconjugates, and HPLC radiochromatograms of radioimmunoconjguates. (acs.org)

Anatomy9

Organisms3

Diseases25

Chemicals and Drugs102

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Anthropology, Education, Sociology and Social Phenomena1

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