Loading...
  • citrate
  • Three specific pyruvate cycles are generally considered, each named for the principal molecule exported from the mitochondrion: malate, citrate, and iso-citrate.Other variants may exist, such as dissipative or "futile" pyruvate cycles. (wikipedia.org)
  • oxidation
  • METHODS: Phenylacetic acid (5 mmol/l) was used to inhibit pyruvate carboxylase in isolated rat islets, which were then assessed for insulin secretion, fuel oxidation, ATP:ADP ratio, respiration, mitochondrial membrane potential, exocytosis and ATP-sensitive K(+) channel (K(ATP)-channel) conductance. (lu.se)
  • glutamate
  • Alanine aminotransferase will cleave off the amino group from alanine and binds it to 2-oxoglutarate which generates pyruvate from alanine and glutamate from 2-oxoglutarate. (wikipedia.org)
  • reaction
  • The reaction proceeds via the removal of a proton from pyruvate, by an as yet unidentified active site residue, to generate an enolate intermediate. (wikipedia.org)
  • cells
  • Pyruvate carboxylase also plays a role in the formation of the protective sheath that surrounds certain nerve cells (myelin) and the production of brain chemicals called neurotransmitters. (wikipedia.org)
  • Citrate
  • Three specific pyruvate cycles are generally considered, each named for the principal molecule exported from the mitochondrion: malate, citrate, and iso-citrate.Other variants may exist, such as dissipative or "futile" pyruvate cycles. (wikipedia.org)
  • the second phase is the subsequent metabolism of these trioses either in the gluconeogenic pathway for glycogen replenishment and/or the complete metabolism in the fructolytic pathway to pyruvate, which enters the Krebs cycle, is converted to citrate and subsequently directed toward de novo synthesis of the free fatty acid palmitate. (wikipedia.org)
  • maize
  • The crystal structure of PEP carboxylase in multiple organisms, including Zea mays (maize), and Escherichia coli has been determined. (wikipedia.org)
  • Subunit
  • When illuminated the chloroplasts isolated from light-grown potato tuber tissue incorporated I3SImethionine into polypeptides, one of which has been idenified as the large subunit of Ribulose-1,5-bisphosphate carboxylase. (studymode.com)
  • synthesis
  • Further, the activities of both PYR carboxylase and PEP carboxylase were less than as compared to maximum lysine synthesis case. (thefreedictionary.com)
  • In this paper we present evidence, based on ultracentrifugal sedimentation and immunoprecipitation, that the lightmediated synthesis of Ribulose-1,5-bisphosphate carboxylase began 1 day after illumination with white light. (studymode.com)
  • thus
  • Pyruvate is converted back to PEP in the mesophyll cells, and the cycle begins again, thus actively pumping CO2. (wikipedia.org)