• Benzene, benzo(a)pyrene (BaP), and lead in mainstream smoke from cigars, roll-your-own (RYO) cigarette and pipe tobaccos were sampled to evaluate their potential health significance. (nih.gov)
  • Cells from the bronchioloalveolar carcinoma cell line A549 were exposed to benzo(a)pyrene (B[a]P) for 24 weeks, and morphology, proliferative activity, and gene expression profiles were analyzed. (nih.gov)
  • Information on benzo(a)pyrene (BaP), an indicator species for polycyclic aromatic hydrocarbons (PAHs), for use in responding to chemical incidents. (www.gov.uk)
  • Benzo[a]pyrene ( BaP ) acts as an indicator species for PAH contamination. (www.gov.uk)
  • The carcinogenic metabolite of benzo(a)pyrene has 4 chiral centers. (chemicalforums.com)
  • Exposure of iron foundry workers to polycyclic aromatic hydrocarbons: benzo(a)pyrene-albumin adducts and 1-hydroxypyrene as biomarkers for exposure. (bmj.com)
  • Exposure to polycyclic aromatic hydrocarbons (PAHs) in foundry workers has been evaluated by determination of benzo(a)pyrene-serum albumin adducts and urinary 1-hydroxypyrene. (bmj.com)
  • Benzo(a)pyrene binding to albumin and 1-hydroxypyrene were quantitatively measured by enzyme linked immunosorbent assay (ELISA) and reverse phase high performance liquid chromatography (HPLC), respectively. (bmj.com)
  • Median benzo(a)pyrene-albumin adduct concentrations (10-90% percentiles) were similar in foundry workers (smokers 0.55 (0.27-1.00) and non-smokers 0.58 (0.17-1.15)) pmol/mg albumin and age matched controls (smokers 0.57 (0.16-1.45) and non-smokers 0.70 (0.19-1.55) pmol/mg albumin). (bmj.com)
  • There was no correlation between the concentrations of 1-hydroxypyrene and benzo(a)pyrene-albumin adducts. (bmj.com)
  • Smoking did not affect the concentrations of 1-hydroxypyrene or benzo(a)pyrene-albumin adducts. (bmj.com)
  • In this study, the human bronchial epithelial cells (16HBE) were treated five times with 1 ?M benzo(a)pyrene (BaP), followed by 2 passages culture, and thein vitroBaP-induced malignant transformation of 16HBE cells was established. (eurekamag.com)
  • Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (BaP), are ubiquitous environmental pollutants found in tobacco smoke, air pollution, and grilled foods. (escholarship.org)
  • This research is aimed to prove the role of mahkota dewa polyphenol in the cell proliferation inhibition and induct lung carcinogenesis apoptosis in strain Balb/c mice which inducted with benzo(a)pyrene (BaP). (undip.ac.id)
  • Penelitian ini bertujuan membuktikan peran polifenol mahkota dewa dalam menginhibisi proliferasi sel dan menginduksi apoptosis pada mencit strain Balb/c hasil induksi Benzo(a)pyrene (BaP). (undip.ac.id)
  • This report presents key data and expert opinions on the toxicity and intake of Benzo a pyrene (BaP). (eugris.info)
  • Benzo(a)pyrene (BaP) is a compound in a group of chemicals called polycyclic aromatic hydrocarbons (PAHs). (chej.org)
  • ABSTRACT: BACKGROUND: Benzo[a]pyrene (B[a]P) exposure induces DNA adducts at all stages of spermatogenesis and in testis, and removal of these lesions is less efficient in nucleotide excision repair deficient Xpc-/- mice than in wild type mice. (maastrichtuniversity.nl)
  • Exposure to benzo(a)pyrene affected the expression of genes that are involved in cell cycle regulation in both genotypes, indicating that the presence of unrepaired DNA damage in testis blocks cell proliferation to protect DNA integrity in both DNA repair proficient and deficient animals. (maastrichtuniversity.nl)
  • Seven PNA's (naphthalene, fluorene, phenanthrene, pyrene, chrysene, benzo[b]fluoranthrene, benzo[a]pyrene) were detected at trace concentrations (1 to 34 ppm) in bulk samples of the WCO. (cdc.gov)
  • Roberto A, Larsson BS, Tjälve H. Uptake of 7,12-dimethylbenz(a)anthracene and benzo(a)pyrene in melanin-containing tissues. (medscape.com)
  • Les Caves de Pyrene is an importer, agent, distributor, and retailer of many wines from around the world. (lescaves.co.uk)
  • Dose-response relations between total PAH, pyrene, carcinogenic PAHs, and 1-hydroxypyrene for smokers, and polycyclic aromatic hydrocarbons adsorbed to dust for non-smokers are suggested. (bmj.com)
  • Pyrene is a polycyclic aromatic hydrocarbon (PAH) consisting of four fused benzene rings, resulting in a flat aromatic system. (wikipedia.org)
  • Indeno(1,2,3-cd)pyrene is a polycyclic aromatic hydrocarbon, or PAH, released from combustion of fossil fuels and waste incinerators. (ewg.org)
  • As a peri-fused PAH, pyrene is much more resonance-stabilized than its five-member-ring containing isomer fluoranthene. (wikipedia.org)
  • Degradation of pyrene and fluoranthene by Mycobacterium sp. (ub.edu)
  • phenanthrene, and pyrene. (cdc.gov)
  • Pyrene Brass Fire Extinguisher, in excellent condition, fantastic original markings, as fitted to most US/UK WW2 military vehicles. (saracenexports.com)
  • Beautiful brass industrial Pyrene Fire Extinguisher - Hand Pump Type - will make a great decorative item or lamp conversion. (pampicks.com)
  • Its derivatives are also valuable molecular probes via fluorescence spectroscopy, having a high quantum yield and lifetime (0.65 and 410 nanoseconds, respectively, in ethanol at 293 K). Pyrene was the first molecule for which excimer behavior was discovered. (wikipedia.org)
  • Lu, P 2009, ' Nucleic acid-induced aggregation and pyrene excimer formation ', Organic letters , vol. 11, no. 4302-5. (vu.nl)
  • The purchasing utility is not required to test for or report Indeno[1,2,3-cd]pyrene, but it likely has the contaminant in its water supply. (ewg.org)
  • Pyrene forms during incomplete combustion of organic compounds. (wikipedia.org)
  • Experiments in pigs show that urinary 1-hydroxypyrene is a metabolite of pyrene, when given orally. (wikipedia.org)
  • Charge transfer (when the neutral metal has a higher ionization energy than the pyrene), pyrene dimerization, oxidation by residual oxygen, and protonation by ubiquitous water in the instrument may also take place. (srce.hr)
  • An integrated approach of bioassay and molecular docking to study the dihydroxylation mechanism of pyrene by naphthalene dioxygenase in Rhodococcus sp. (brenda-enzymes.org)
  • Pyrene-PEG-COOH, with a pyrene and a carboxyl group at each end of the molecular chain, is a fluorescent heterofunctional PEG derivative. (bocsci.com)
  • Pyrene and its derivatives are used commercially to make dyes and dye precursors, for example pyranine and naphthalene-1,4,5,8-tetracarboxylic acid. (wikipedia.org)
  • Pyrene's fluorescence emission spectrum is very sensitive to solvent polarity, so pyrene has been used as a probe to determine solvent environments. (wikipedia.org)
  • A Pyrene based Schiff bases probe 3 and 5 has been synthesized and demonstrated to study the photophysical behaviour towards different metals and anions. (thapar.edu)
  • In accordance with the "Data Protection" law of 6 January 1978 amended in 2004, you have a right to access and correct information concerning you, which you can exercise by contacting Forges de Pyrène - route de Paris - 09330 MONTGAILHARD - [email protected]. (forges-de-pyrene.com)
  • pyrene from the view of nanoclusters: size- and nanoplastic adsorption-dependent bioavailability. (bvsalud.org)
  • Although it is not as problematic as benzopyrene, animal studies have shown pyrene is toxic to the kidneys and liver. (wikipedia.org)
  • Pyrene-PEG-COOH can react with amino groups and thus attach to biomolecules or cell surfaces. (bocsci.com)
  • PEG linkers between pyrene and carboxylic acid groups offer better water solubility, fewer steric hindrances and higher stability. (bocsci.com)
  • 2005). 'Gas Phase Ligation Kinetics of Metal Monocations with Pyrene', Croatica Chemica Acta , 78(2), str. (srce.hr)
  • Kazazić S, Kazazić SP, Klasinc L, Rožman M, Srzić D. Gas Phase Ligation Kinetics of Metal Monocations with Pyrene. (srce.hr)
  • Pyrene undergoes a series of hydrogenation reactions and is susceptible to halogenation, Diels-Alder additions, and nitration, all with varying degrees of selectivity. (wikipedia.org)
  • Pyrenes are strong electron donor materials and can be combined with several materials in order to make electron donor-acceptor systems which can be used in energy conversion and light harvesting applications. (wikipedia.org)
  • Manufactured by Pyrene Company Ltd, Brentford, England. (pampicks.com)
  • title = "Transfer of phospholipase A-resistant pyrene-dialkyl-glycerophosphocholine to plasma lipoproteins. (elsevierpure.com)
  • Benzo[a]pyrene is a polycyclic aromatic hydrocarbon, or PAH, released from combustion of fossil fuels and waste incinerators. (ewg.org)
  • The EWG Health Guideline of 0.007 ppb for benzo[a]pyrene was defined by the California Office of Environmental Health Hazard Assessment as a public health goal, the level of a drinking water contaminant that does not pose a significant health risk. (ewg.org)
  • The legal limit for benzo[a]pyrene, established in 1992, was based on analytical detection limits at the time that the standard was set. (ewg.org)
  • Benzo[a]pyrene (B[a]P), a polycyclic hydrocarbon, plays a pivotal role in lung carcinogenesis. (nih.gov)
  • The alarming rise in behavioral and cognitive disorders is linked to early life exposure to environmental chemicals, such as benzo[a]pyrene (BAP), the globally ubiquitous pollutant on which this project focuses. (nih.gov)
  • Based on the identification of GNMT as a 4 S polyaromatic hydrocarbon-binding protein, we used liver cancer cell lines that expressed GNMT either transiently or stably in cDNA transfections to analyze the role of GNMT in the benzo(a)pyrene (BaP) detoxification pathway. (nih.gov)
  • The metabolism of benzo[ a ]pyrene and eight benzo[ a ]pyrene derivatives to products mutagenic to Salmonella typhimurium strain TA98 was evaluated with a highly purified, cytochrome P-448-dependent monooxygenase system free of epoxide hydrase. (aspetjournals.org)
  • Benzo[ a ]pyrene 7,8-quinone was not intrinsically mutagenic to the bacteria and could not be metabolically activated. (aspetjournals.org)
  • Sensitivity to benzo(a)pyrene diol-epoxide associated with risk of breast cancer in young women and modulation by glutathione S-transferase polymorphisms: a case-control study. (nih.gov)
  • To test this hypothesis, we evaluated benzo(a)pyrene diol-epoxide (BPDE)-induced mutagen sensitivity and polymorphisms of GSTM1 and GSTT1 in a pilot case-control study of breast cancer. (nih.gov)
  • A study was conducted to evaluate the rate of Benzo[a]pyrene apparent loss from a previously uncontaminated agricultural clay loam soil and to determine the effect of cow manure, as organic substrate amendment, on B[a]P apparent loss. (usu.edu)
  • Exposure to benzo(a)pyrene (BaP) was associated with cognitive impairments and some Alzheimer's disease (AD)-like pathological changes. (biomedcentral.com)
  • The CFS announced on 7th July, 2016 (Thur) that three bottled sunflower oil samples were detected to contain a harmful contaminant, benzo[a]pyrene (BaP) . (enjoi.com.hk)
  • Exceeding action level of Benzo[a]pyrene (BaP) A spokesman for the CFS said, 'The CFS collected the abovementioned samples from two retail outlets in Central for testing. (enjoi.com.hk)
  • What is Benzo[a]pyrene (BaP)? Benzo[a]pyrene (BaP) is a kind of polycyclic aromatic hydrocarbons (PAHs) which are contaminants ubiquitous in the environment. (enjoi.com.hk)
  • Our previous post talked about the benzo[a]pyrene. (enjoi.com.hk)
  • An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Benzo(a)pyrene (50-32-8). (nih.gov)
  • Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish. (oregonstate.edu)
  • Benzo[a]pyrene (B[a]P) is a well-known genotoxic polycylic aromatic compound whose toxicity is dependent on signaling via the aryl hydrocarbon receptor (AHR). (oregonstate.edu)
  • Exposure to benzo[a]pyrene during development resulted in transgenerational inheritance of neurobehavioral and physiological deficiencies. (oregonstate.edu)
  • Benzo[a]pyrene (BaP), a major environmental pollutant, activates aryl hydrocarbon receptor (AHR), induces its cytoplasmic-to-nuclear translocation and upregulates the production of cytochrome P450 1A1 (CYP1A1), a xenobiotic metabolizing enzyme which metabolize BaP. (elsevierpure.com)
  • This document specifies a method for the determination of benzo[a]pyrene (B[a]P) in the total particulate matter of cigarette mainstream smoke with an intense smoking regime using gas chromatography/mass spectrometry (GC/MS) with cyclohexane as extraction solvent. (iso.org)
  • At 20 0 C , benzo(a)pyrene is a solid with very low volatility. (gc.ca)
  • Fragments of benzo(a)pyrene can also be carried into and deposited at the bottom of waterways, where they will very slowly dissolve. (gc.ca)
  • Once the source has been removed, the adsorbed benzo(a)pyrene will take a very long time to disappear, being released in its gaseous or dissolved forms. (gc.ca)
  • Benzo(a)pyrene should be handled with care, as it is toxic. (gc.ca)
  • Benzo(a)pyrene is a polycyclic aromatic hydrocarbon (PAH). (gc.ca)
  • Benzo(a)pyrene, like most individual PAHs , has very limited or no known uses, except as reagents in biochemical or cancer research. (gc.ca)
  • Benzo(a)pyrene is more likely to be found mixed with other PAHs in commercial products like coal tar, coal tar pitch, creosote, bitumen and asphalt. (gc.ca)
  • The metabolic pathways and enzyme-inducing effects of specific PAHs, such as benz[a]pyrene, have been actively studied to elucidate cancer potential and causal mechanisms (Ramesh et al. (cdc.gov)
  • Degradation of PAHs in the Prestige fuel oil by a pyrene-degrading mycobacteria. (ub.edu)
  • The two probes contained an anthracene and pyrene group with the increased size and angularity of the pyrene ring in pyrene-based imidazolium (PIM) raising the hydrophobicity or π - π stacking and sensitivity of the probe towards all mono-, di-, and trinitrophenols even under harsh conditions (pH 4-8). (mahidol.ac.th)
  • phenanthrene, and pyrene. (cdc.gov)
  • 1-Hydroxypyrene as an indicator of pyrene exposure. (nih.gov)
  • abstract = "1-Diphenylphosphinopyrene (1-PyP) and 1,6-bis(diphenylphosphino)pyrene (1,6-PyP) can be metalated at C5 and C10 to give cyclometalated complexes [M(L)(1-PyP-H)]+ and [M2(L)2(1,6-PyP)]2+ (M = Pd or Pt, L = diphosphines). (edu.hk)
  • As a peri-fused PAH, pyrene is much more resonance-stabilized than its five-member-ring containing isomer fluoranthene. (wikipedia.org)
  • Construction and Characterization of Pyrene-alkyne Based Porous Frameworks[J]. Acta Chimica Sinica , 2013, 71(12): 1598-1602. (sioc-journal.cn)
  • Solid-state NMR characterization of pollutant-soil organic matter interactions: Pyrene sorption to cuticular materials. (huji.ac.il)
  • Pyrene and its derivatives are used commercially to make dyes and dye precursors, for example pyranine and naphthalene-1,4,5,8-tetracarboxylic acid. (wikipedia.org)
  • Although it is not as problematic as benzopyrene, animal studies have shown pyrene is toxic to the kidneys and liver. (wikipedia.org)
  • Pyrene forms during incomplete combustion of organic compounds. (wikipedia.org)
  • Chapter 4 presents the effect of Elliott soil HA (ESHA) amendment on pyrene solubility in soil slurry systems and pyrene mineralization in unsaturated soil microcosms. (brownwalker.com)
  • Adsorption and desorption behavior of an anionic pyrene chromophore in sequentially deposited polyelectrolyte-dye thin films. (mpg.de)
  • Genetic Toxicity Evaluation of Pyrene in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)
  • KMS is a new strain isolated from the land treatment units of the Libby site and has been found to utilize pyrene as a carbon and energy source. (brownwalker.com)
  • After using a lock handle and refill immediately shake extinguisher to remove liquid in discharge to use only Pyrene fire extinguishing liquid after or other substitutes will damage extinguisher and render use on electrical fires dangerous. (purplepigeontreasures.com)
  • They turned out to be Celtic , and because they were so old and so large and so close to the source of the Danube, some archaeologists figured that they might actually be the ruins of the ancient city of Pyrene . (thelongestway.com)
  • Pyrenes are strong electron donor materials and can be combined with several materials in order to make electron donor-acceptor systems which can be used in energy conversion and light harvesting applications. (wikipedia.org)
  • Click here to place an order for determining Pyrene. (celignis.com)
  • RESULTS: The paving workers had inhalation (mean 0.3 micro g/m3) and dermal (5.7 ng/cm2) exposures to pyrene that were significantly higher than the milling workers. (cdc.gov)
  • Chapter 5 describes the overall effect of ESHA amendment on pyrene distribution in a soil slurry system. (brownwalker.com)
  • Experiments in pigs show that urinary 1-hydroxypyrene is a metabolite of pyrene, when given orally. (wikipedia.org)
  • During multiple consecutive workshifts, personal air and dermal samples were collected from each worker and analyzed for pyrene. (cdc.gov)