• cytosolic
  • TGF beta receptor 1 has been shown to interact with: Caveolin 1, Endoglin, FKBP1A, FNTA, Heat shock protein 90kDa alpha (cytosolic), member A1 Mothers against decapentaplegic homolog 7, PPP2R2A, STRAP, TGF beta 1, and TGF beta receptor 2. (wikipedia.org)
  • sequence
  • Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed. (uniprot.org)
  • Pyruvate kinase catalyzes the last step within glycolysis, the dephosphorylation of phosphoenolpyruvate to pyruvate, and is responsible for net ATP production within the glycolytic sequence. (wikipedia.org)
  • In fact, sequence homology searches have shown that two other Pim-1-like kinases, Pim-2 and Pim-3, are structurally and functionally similar. (wikipedia.org)
  • tumor
  • When PKM2 is mainly in the less active dimeric form, which is the case in tumor cells, all glycolytic intermediates above pyruvate kinase accumulate and are channelled into synthetic processes, which branch off from glycolytic intermediates such as nucleic acid-, phospholipid-, and amino acid synthesis. (wikipedia.org)
  • mammalian
  • The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells. (springer.com)
  • It is composed of ataxia telangiectasia mutated (ATM), ataxia telangiectasia and Rad3 related (ATR), DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR). (wikipedia.org)