TRNAPhosphataseTransmembrane proteinSynthaseHypothetical proteinKinaseInterproscanDomainDehydrogenasePEBPFamilyFunctionActivityFactorCarboxyl methyltransferasePIMTIsoaspartyl methyltransferaseSpontaneous decomposition of normalAspartic AcidResiduesDeficiencyPCMTD1NCBIInsulinMitochondrialInteractionsMiceACIDMembrane proteinProtective roleSubspOntologyUbiquitinMotifHumansRepairModificationCellsSitesAnalysis
TRNA1
- 42520) hypothetical protein CP001857 tRNA Arcpr_R0002 complement(42639. (go.jp)
Phosphatase3
- protein phosphatase 1 regulatory inh. (gsea-msigdb.org)
- Description: A sandwich ELISA kit for detection of Protein Tyrosine Phosphatase, Non Receptor Type 11 from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (worldcarecouncil.org)
- Description: A sandwich quantitative ELISA assay kit for detection of Human Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) in samples from tissue homogenates or other biological fluids. (worldcarecouncil.org)
Transmembrane protein2
- transmembrane protein 191C [Source:H. (gsea-msigdb.org)
- transmembrane protein 156 [Source:HG. (gsea-msigdb.org)
Synthase1
- 38678) Cobalamin-independent synthase MetE domain protein CP001857 CDS Arcpr_0044 complement(38683. (go.jp)
Hypothetical protein14
- 9766 conserved hypothetical protein CP001857 CDS Arcpr_0009 complement(9767. (go.jp)
- 10378) hypothetical protein CP001857 CDS Arcpr_0010 complement(10422. (go.jp)
- 13428) hypothetical protein CP001857 CDS Arcpr_0013 complement(13425. (go.jp)
- 13751) hypothetical protein CP001857 CDS Arcpr_0014 complement(13789. (go.jp)
- 19702 hypothetical protein CP001857 CDS Arcpr_0022 complement(19723. (go.jp)
- 21298 hypothetical protein CP001857 CDS Arcpr_0025 complement(21287. (go.jp)
- 23242 hypothetical protein CP001857 CDS Arcpr_0028 23232. (go.jp)
- 29158) hypothetical protein CP001857 CDS Arcpr_0035 complement(29143. (go.jp)
- 29526) hypothetical protein CP001857 CDS Arcpr_0036 29596. (go.jp)
- 36678) hypothetical protein CP001857 CDS Arcpr_0042 complement(36769. (go.jp)
- 43572) hypothetical protein CP001857 CDS Arcpr_0052 43655. (go.jp)
- 47353) hypothetical protein CP001857 CDS Arcpr_0058 complement(47350. (go.jp)
- 52977 conserved hypothetical protein CP001857 CDS Arcpr_0062 complement(52960. (go.jp)
- 53727) hypothetical protein CP001857 CDS Arcpr_0063 complement(53793. (go.jp)
Kinase1
- Protein kinase A anchor protein, nuclear localisation signal domain [Interproscan]. (ntu.edu.sg)
Interproscan7
- Protein of unknown function (DUF520) [Interproscan]. (ntu.edu.sg)
- Enoyl-(Acyl carrier protein) reductase [Interproscan]. (ntu.edu.sg)
- protein_coding" "Cz01g39090.t1","No alias","Chromochloris zofingiensis","Protein N-terminal asparagine amidohydrolase [Interproscan]. (ntu.edu.sg)
- protein_coding" "Cz03g09200.t1","No alias","Chromochloris zofingiensis","UV radiation resistance protein/autophagy-related protein 14 [Interproscan]. (ntu.edu.sg)
- protein_coding" "Cz03g33270.t1","No alias","Chromochloris zofingiensis","Domain of unknown function DUF155 [Interproscan]. (ntu.edu.sg)
- protein_coding" "Cz10g28290.t1","No alias","Chromochloris zofingiensis","Chorismate pyruvate-lyase Rv2949c-like [Interproscan]. (ntu.edu.sg)
- Protein N-terminal asparagine amidohydrolase [Interproscan]. (ntu.edu.sg)
Domain6
- Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 is a protein that in humans is encoded by the PCMTD1 gene. (wikipedia.org)
- 6097 beta-lactamase domain protein CP001857 CDS Arcpr_0005 complement(6094. (go.jp)
- 23029 TrkA-N domain protein CP001857 CDS Arcpr_0027 23060. (go.jp)
- 25637 PKD domain containing protein CP001857 CDS Arcpr_0030 complement(25624. (go.jp)
- 30270 beta-lactamase domain protein CP001857 CDS Arcpr_0037 complement(30271. (go.jp)
- 51868 SMC domain protein CP001857 CDS Arcpr_0061 51865. (go.jp)
Dehydrogenase1
- protein_coding" "AAC74323","adhE","Escherichia coli","fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase [Ensembl]. (ntu.edu.sg)
PEBP1
- 45756) PEBP family protein CP001857 CDS Arcpr_0056 45795. (go.jp)
Family4
Function4
- 20759) Protein of unknown function DUF54 CP001857 CDS Arcpr_0024 20798. (go.jp)
- 43228) protein of unknown function UPF0153 CP001857 CDS Arcpr_0051 complement(43225. (go.jp)
- 44065 protein of unknown function UPF0047 CP001857 CDS Arcpr_0053 complement(44048. (go.jp)
- 45260 protein of unknown function DUF121 CP001857 CDS Arcpr_0055 complement(45235. (go.jp)
Activity1
- Predicted to enable protein-L-isoaspartate (D-aspartate) O-methyltransferase activity. (nih.gov)
Factor2
- The basic helix-loop-helix transcription factor SHARP1 (Split and Hairy-related Protein 1) has been identified as a suppressor of the metastatic behavior of TNBC. (bvsalud.org)
- 40535) Transcription factor TFIIB cyclin-related protein CP001857 CDS Arcpr_0047 complement(40887. (go.jp)
Carboxyl methyltransferase1
- This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. (nih.gov)
PIMT3
- A prognostic association between the novel chaperone protein-L-isoaspartate (D-aspartate) O -methyltransferase (PIMT) and lung adenocarcinoma has recently been reported. (oncotarget.com)
- Protein L-isoaspartyl O-methyltransferase (PIMT) converts isoaspartyl residues to conventional methylated forms in cells undergoing stress-induced protein damage. (bvsalud.org)
- Separately, PIMT also suppressed ICAM-1 expression by inhibiting its N-glycosylation, causing effects on protein stability that ultimately translated into reduced EC(endothelial cell)-leukocyte interactions. (bvsalud.org)
Isoaspartyl methyltransferase3
- 13. The microRNA 15a/16-1 cluster down-regulates protein repair isoaspartyl methyltransferase in hepatoma cells: implications for apoptosis regulation. (nih.gov)
- 18. Proteomic identification of novel substrates of a protein isoaspartyl methyltransferase repair enzyme. (nih.gov)
- l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain. (ucla.edu)
Spontaneous decomposition of normal2
- It initiates the repair of proteins damaged by the spontaneous decomposition of normal L-aspartic acid and L-asparagine residues. (nih.gov)
- Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. (nih.gov)
Aspartic Acid1
- A PROTEIN O-METHYLTRANSFERASE that recognizes and catalyzes the methyl esterification of ISOASPARTIC ACID and D-ASPARTIC ACID residues in peptides and proteins. (nih.gov)
Residues1
- The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. (nih.gov)
Deficiency1
- Deficiency of protein-L-isoaspartate (D-aspartate) O -methyl-transferase expression under endoplasmic reticulum stress promotes epithelial mesenchymal. (oncotarget.com)
PCMTD12
- Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 is a protein that in humans is encoded by the PCMTD1 gene. (wikipedia.org)
- Human Protein-l-isoaspartate O-Methyltransferase Domain-Containing Protein 1 (PCMTD1) Associates with Cullin-RING Ligase Proteins. (ucla.edu)
NCBI1
- Description of the protein which includes the UniProt Function and the NCBI Gene Summary. (nih.gov)
Insulin1
- 9. Activation of the PI3K/Akt signal transduction pathway and increased levels of insulin receptor in protein repair-deficient mice. (nih.gov)
Mitochondrial1
- 5. The protective role of protein L-isoaspartyl (D-aspartate) O-methyltransferase for maintenance of mitochondrial morphology in A549 cell. (nih.gov)
Interactions1
- Through network analysis of protein-protein interactions (PPI), we identified diverse clusters of DEPs in the lung and serum samples. (bvsalud.org)
Mice3
- 10. Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice. (nih.gov)
- 16. Altered levels of S-adenosylmethionine and S-adenosylhomocysteine in the brains of L-isoaspartyl (D-Aspartyl) O-methyltransferase-deficient mice. (nih.gov)
- The common differentially expressed proteins (DEPs) were identified based on combined proteomic analysis of serum and lung samples in direct ARDS mice model. (bvsalud.org)
ACID1
- This putative galanin isomer can either result from the presence of an iso-aspartate or D-amino acid residue in the peptide. (illinois.edu)
Membrane protein1
- Manual 26.29 HN - 2002 MH - Activin Receptors UI - D029404 MN - D8.586.913.696.620.682.700.62 MN - D12.776.543.750.750.400.820.500 MS - Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES, thus also named activin receptor-like kinases (ALK's). (nih.gov)
Protective role1
- The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. (nih.gov)
Subsp1
- RS20_BEII9 30S ribosomal protein S20 OS=Beijerinckia indica subsp. (isoelectricpointdb.org)
Ontology1
- Classes for this protein according to by Drug Target Ontology (DTO). (nih.gov)
Ubiquitin1
- Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein. (nih.gov)
Motif1
- IsoDGR binds to RGD-binding site in inverted orientation compared to proteins that contain RGD motif ( Spitaleri,2008 ). (eu.org)
Humans1
- Eight of the human integrins: αvβ1, αvβ3, αvβ5, αvβ6, αvβ8, α5β1, α8β1 and αIIbβ3 can recognize ligands with RGD motifs ( D'Souza,1991 ) present in several proteins from humans and pathogens or parasites. (eu.org)
Repair1
- It plays a role in the repair and/or degradation of damaged proteins. (nih.gov)
Modification1
- Protein Methylation and Translation: Role of Lysine Modification on the Function of Yeast Elongation Factor 1A. (ucla.edu)
Cells2
- The Protein L-Isoaspartyl (D-Aspartyl) Methyltransferase Regulates Glial-to-Mesenchymal Transition and Migration Induced by TGF-β1 in Human U-87 MG Glioma Cells. (nih.gov)
- Eight of the 24 human integrins, which resemble the evolutionarily most ancient metazoan integrins, can recognize RGD and RGD-like sequence patterns in their ligands: components of the extracellular matrix (ECM), cell surface proteins of cells or other extracellular signalling proteins. (eu.org)
Sites1
Analysis1
- Classes for this protein according to Protein ANalysis THrough Evolutionary Relationships (PANTHER) Classification System. (nih.gov)