• NEUTROPHILS
  • Up-regulation of ALOX5 may occur during the maturation of leukocytes and in human neutrophils treated with granulocyte macrophage colony-stimulating factor and then stimulated with physiological agents. (wikipedia.org)
  • 1988
  • Baeuerle, P. A. and Baltimore, D. (1988) IKB: A specific inhibitor of the NF-KB transcription factor. (springer.com)
  • analogs
  • Synthetic analogs of TXA2 that activate TP but are relatively resistant to spontaneous and metabolic degradation include SQ 26655, AGN192093, and EP 171, all of which have binding and activating potencies for TP similar to I-BOP. (wikipedia.org)
  • tissue
  • In 12 rabbits, we found tissue levels of platelet-activating factor measured by the release of serotonin from washed platelets to be elevated by approximately 20-fold in spinal cord injured by 25 minutes of ischemia and 2 hours of reperfusion (2.80 +/- 0.98 ng/g) compared with that in normal spinal cord (0.15 +/- 0.06 ng/g, p less than 0.01). (ahajournals.org)
  • 1993
  • Liou, H. C. and Baltimore, D. (1993) Regulation of the NF-KB/rel transcription factor and IKB inhibitor system. (springer.com)