adenoma
- Patients with nonfunctioning pituitary adenoma in whom surgical intervention planned based on current guidelines will serve as a control group. (clinicaltrials.gov)
- Examples include: Adrenal tumor Pituitary adenoma The most common form is thyroid cancer. (wikipedia.org)
- Pituitary adenomas are generally divided into three categories dependent upon their biological functioning: benign adenoma, invasive adenoma, and carcinomas. (wikipedia.org)
- A patient with pituitary adenoma may present with visual field defects, classically bitemporal hemianopsia. (wikipedia.org)
- Lateral expansion of a pituitary adenoma can also compress the abducens nerve, causing a lateral rectus palsy. (wikipedia.org)
- Also, a pituitary adenoma can cause symptoms of increased intracranial pressure. (wikipedia.org)
- Approximately 90-95% of acromegaly cases are caused by a pituitary adenoma and it most commonly affects middle aged adults, Acromegly can result in severe disfigurement, serious complicating conditions, and premature death if unchecked. (wikipedia.org)
- In 1903 Erdheim described the case of an acromegalic patient with a pituitary adenoma and three enlarged parathyroid glands. (wikipedia.org)
Tumors
- For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned. (icd10data.com)
- This is a Phase 2 open-label, single-treatment group, baseline-controlled study designed to verify product safety, gather data on the percentage of subjects with pituitary tumors with increased uptake of FolateScan in tumors and correlate the immunohistochemical staining findings with the FolateScan images, in subjects with pituitary tumors. (clinicaltrials.gov)
- The purpose of the family study is to investigate the genetic basis for the development of pituitary tumors by assessing the prevalence of pituitary tumors in relatives of probands with the disease as compared to the prevalence in unrelated spouses sharing a similar environment. (clinicaltrials.gov)
- The major purpose of this study is to evaluate the changes of multiple organs in patients with growth hormone-secreting pituitary tumors before and after surgery. (clinicaltrials.gov)
- The control group consists of patients with nonfunctioning pituitary tumors who will undergo surgical removal. (clinicaltrials.gov)
- Pituitary adenomas are tumors that occur in the pituitary gland, and account for about 15% of intracranial neoplasms. (wikipedia.org)
- Pituitary adenomas are tumors that occur in the pituitary gland. (wikipedia.org)
- Large pituitary tumors can paradoxically elevate blood prolactin levels due to the "stalk effect. (wikipedia.org)
- Play media A 1972 study compared neoplasms in "Sprague-Dawley" rats from six different commercial suppliers and found highly significant differences in the incidences of endocrine and mammary tumors. (wikipedia.org)
adenomas
- During the last decades Clinics of Neurosurgery and Otorhinolaryngology of the Medicomilitary Academy gained a rather profound experience in surgery of pituitary adenomas, using a transnasosphenoidal approach. (neva.ru)
- There are absolute and particular indications for surgical treatment of different pituitary adenomas. (neva.ru)
- Pituitary adenomas can cause compression of optic nerves and chiasm, which will lead to damage of vision. (clinicaltrials.gov)
- This study aims to evaluate the predictive factors for recovery of vision in patients with pituitary adenomas following trans-sphenoidal surgery. (clinicaltrials.gov)
- Patients with pituitary adenomas at Huashan Hospital will be screened. (clinicaltrials.gov)
- Pituitary adenomas is a very common disease, but the cause and genetics hasn't been identified. (clinicaltrials.gov)
- The investigators are going to use genome-wide association study to identify genes that may be related to pituitary adenomas. (clinicaltrials.gov)
- Patients diagnosed with pituitary adenomas and healthy controls will be included. (clinicaltrials.gov)
- To evaluate the calcium and calcitriol/PTH levels in patients with acromegaly compared to patients with nonfunctioning pituitary adenomas, with subanalyses based on presence of hyperprolactinemia in either group. (clinicaltrials.gov)
- Patients with uncontrolled acromegaly and nonfunctioning pituitary adenomas presenting to the Emory University Pituitary Center for medical or surgical treatment. (clinicaltrials.gov)
- Moreover, GH replacement in nonmalignant tumoral lesions, such as craniopharyngiomas or nonfunctioning pituitary adenomas (NFPAs), is apparently not associated with an increased risk of recurrence or induction of a second tumor (13, 16, 17). (deepdyve.com)
- MEN1 pituitary tumours are adenomas of anterior cells, typically prolactinomas or growth hormone-secreting. (wikipedia.org)
- MEN1 gene mutations and deletions also play a role in the development of hereditary and a subgroup of sporadic pituitary adenomas and were detected in approximately 5% of sporadic pituitary adenomas. (wikipedia.org)
- Most pituitary adenomas are microadenomas, and have an estimated prevalence of 16.7% (14.4% in autopsy studies and 22.5% in radiologic studies). (wikipedia.org)
- Pituitary macroadenomas are the most common cause of hypopituitarism, and in the majority of cases they are non-secreting adenomas. (wikipedia.org)
- While pituitary adenomas are common, affecting approximately one in 6 of the general population, clinically active pituitary adenomas that require surgical treatment are more rare, affecting approximately one in 1000 of the general population. (wikipedia.org)
- Hormone secreting pituitary adenomas cause one of several forms of hyperpituitarism. (wikipedia.org)
- Various types of headaches are common in patients with pituitary adenomas. (wikipedia.org)
- Various psychiatric manifestations have been associated with pituitary disorders including pituitary adenomas. (wikipedia.org)
- reported a case series of 8 patients with a syndrome of pituitary, parathyroid, and pancreatic islet adenomas. (wikipedia.org)
gland
- Endoscopic videomonitoring in a transseptal transsphenoidal approach to the pituitary gland is not only possible, but also expedient, as this method permits to visualize main anatomic landmarks of the sphenoid sinus in a panoramic examination of its cavity and to ensure optimum access to the saddle fundus and structures [2, 7, . (neva.ru)
- A neoplasm without metastatic potential arising from the anterior or the posterior lobe of the pituitary gland. (icd10data.com)
- The MEN1 phenotype is inherited via an autosomal-dominant pattern and is associated with neoplasms of the pituitary gland, the parathyroid gland, and the pancreas (the 3 "P"s). (wikipedia.org)
- An endocrine gland neoplasm is a neoplasm affecting one or more glands of the endocrine system. (wikipedia.org)
- Acromegaly is a syndrome that results when the anterior pituitary gland produces excess growth hormone (GH). (wikipedia.org)
- Findings affecting pituitary function in some JBS patients have included such anomalies as the formation of a glial hamartoma (a neoplasm, or tumor composed of glial cells) on a lobe of the pituitary gland, as well congenital underdevelopment of the anterior pituitary. (wikipedia.org)
- Craniopharyngioma is a type of brain tumor derived from pituitary gland embryonic tissue, that occurs most commonly in children but also in adults in their 50s and 60s. (wikipedia.org)
- Symptoms include: Stunted growth and delayed puberty (in children) General fatigue, loss of muscle mass and tone (in adults) Pituitary insufficiency often occurs to some degree because craniopharyngiomas develop in the area of the pituitary stalk, which can affect the function of the pituitary gland. (wikipedia.org)
- Other reported sites of heterotopic salivary gland tissue are the middle ear, parathyroid glands, thyroid gland, pituitary gland, cerebellar pontine angle, soft tissue medial to sternocleidomastoid, stomach, rectum and vulva. (wikipedia.org)
- Salivary gland neoplasm occurrence within heterotopic salivary gland tissue is rare. (wikipedia.org)
Acromegaly
- Patients diagnosed with acromegaly or a nonfunctioning pituitary who will receive treatment for the pituitary condition. (clinicaltrials.gov)
- Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to acromegaly. (clinicaltrials.gov)
malignant neoplasm
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. (icd10data.com)
- Objective To clarify the incidence of new malignant neoplasm in childhood-onset (CO) and adult-onset (AO) adult cancer survivors (CSs). (deepdyve.com)
anterior
- Growth failure and associated short stature (dwarfism) in JBS can be attributed to growth hormone deficiency caused by diminished anterior pituitary function, with malabsorption of fats playing a subsequent role. (wikipedia.org)
- Rathke's pouch is an embryonic precursor of the anterior pituitary. (wikipedia.org)
pancreas
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified ( C25.9 ). (icd10data.com)
- Since a significant number of gastrinomas are associated with MEN involving other hormone producing organs (pancreas, parathyroids, and pituitary), higher levels of C-peptide together with the presence of a gastrinoma suggest that organs besides the stomach may harbor neoplasms. (wikipedia.org)
prevalence
- Moreover, as a consequence of the primary lesion and its treatment, the prevalence of secondary hormonal pituitary dysfunction is very high (3). (deepdyve.com)
stalk
- If originating superior to the optic chiasm, more commonly in a craniopharyngioma of the pituitary stalk, the visual field defect will first appear as bitemporal inferior quadrantanopia, if originating inferior to the optic chiasm the visual field defect will first appear as bitemporal superior quadrantanopia. (wikipedia.org)
- They arise from the cells along the pituitary stalk, specifically from nests of odontogenic (tooth-forming) epithelium within the suprasellar/diencephalic region and, therefore, contain deposits of calcium that are evident on an x-ray. (wikipedia.org)
- This elevation occurs as a result of the compression of the pituitary stalk, which interferes with the brain's control of prolactin production. (wikipedia.org)
tumorigenesis
- Consequently, alterations of the gene represent a candidate pathogenetic mechanism of pituitary tumorigenesis especially when considered in terms of interactions with other proteins, growth factors, oncogenes play a rule in tumorigenesis. (wikipedia.org)
tissue
- Obtained results are indicative of such main advantages of the method, as a panoramic view of the sphenoid sinus cavity, precise differentiation of neoplastic and intact tissue of the pituitary body, early diagnosis and elimination of liquorrhea. (neva.ru)
psychiatric
- As early as 1916 he described neurologic and psychiatric sequelae of pituitary neoplasms. (wikipedia.org)
posterior
- This occurs due to the absence of a posterior pituitary hormone called antidiuretic hormone (ADH). (wikipedia.org)
patients
- New Neoplasm During GH Replacement in Adults With Pituitary Deficiency Following Malignancy: A... Krzyzanowska-Mittermayer, Katarzyna;Mattsson, Anders F;Maiter, Dominique;Feldt-Rasmussen, Ulla;Camacho-Hübner, Cecilia;Luger, Anton;Abs, Roger 2018-02-01 00:00:00 Abstract Context Data on the association between growth hormone (GH) replacement in patients with GH deficiency (GHD) after malignancies and new neoplasms show conflicting results. (deepdyve.com)
- Conclusions The risk of second malignant neoplasms was increased in CO-CS but not in AO-CS, which illustrates the need to closely follow patients on GH replacement because of a prior malignancy. (deepdyve.com)
- Recent publications have emphasized that patients who survived childhood cancer are at risk for developing a subsequent CNS neoplasm, necessitating further extensive and coordinated research (18). (deepdyve.com)
craniopharyngioma
- Craniopharyngioma is a rare, usually suprasellar neoplasm, which may be cystic, that develops from nests of epithelium derived from Rathke's pouch. (wikipedia.org)
Cancer
- Also searched for Pituitary Neoplasms , Neoplasm , Cancer and more. (clinicaltrials.gov)
- It has indeed been shown that adult survivors of childhood cancer have an increased risk of adverse health outcomes, including an increased risk for second neoplasms (2). (deepdyve.com)
incidental
- A majority of pituitary microadenomas often remain undiagnosed and those that are diagnosed are often found as an incidental finding, and are referred to as incidentalomas. (wikipedia.org)
Study
- The major purpose of this study is to evaluate the changes before and after the pituitary surgery. (clinicaltrials.gov)
Additional
- An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm. (icd10data.com)
development
- Studies have been investigating the association between GH exposure and the development of a subsequent neoplasm (21, 22). (deepdyve.com)
results
- Results After a median follow-up of 5.9 years (2192 patient-years), 15 CO-CS (4.3%) had developed 16 new neoplasms. (deepdyve.com)
syndromes
- Epithelioid blue nevus List of cutaneous neoplasms associated with systemic syndromes Carney Syndrome at eMedicine Carney, J. (wikipedia.org)
insufficiency
- This is very uncommon and occurs with severe pituitary insufficiency. (wikipedia.org)
prolactin levels
- Large pituitary tumors can paradoxically elevate blood prolactin levels due to the "stalk effect. (wikipedia.org)
tumors
- Papillary tumor of the pineal region (PTPR) is a recently described neoplasm that has been formally recognized in the 2007 World Health Organization (WHO) "Classification of Tumors of the Nervous System. (wikipedia.org)
- The critical diagnosis of this neoplasm is often difficult because of its similarity with other primary or secondary papillary lesions of the pineal region, including parenchymal pineal tumors, papillary ependymoma, papillary meningioma, choroid plexus papilloma, and metastatic papillary carcinoma. (wikipedia.org)
- Play media A 1972 study compared neoplasms in "Sprague-Dawley" rats from six different commercial suppliers and found highly significant differences in the incidences of endocrine and mammary tumors. (wikipedia.org)
Craniopharyngioma
- Craniopharyngioma is a rare, usually suprasellar neoplasm, which may be cystic, that develops from nests of epithelium derived from Rathke's pouch. (wikipedia.org)
- Craniopharyngioma is a neoplasm which can arise from the epithelium within the cleft. (wikipedia.org)
Syndrome
- Central precocious puberty can be caused by intracranial neoplasm, infection (most commonly central nervous system tuberculosis especially in developing countries), trauma, hydrocephalus, and Angelman syndrome. (wikipedia.org)
hereditary
- MEN1 gene mutations and deletions also play a role in the development of hereditary and a subgroup of sporadic pituitary adenomas and were detected in approximately 5% of sporadic pituitary adenomas. (wikipedia.org)
neuroendocrine
- Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor which originates from parafollicular c-cells producing calcitonin and comprises 2.1% of thyroid neoplasms. (biomedcentral.com)
hormones
- Central precocious puberty can be treated by suppressing the pituitary hormones that induce sex steroid production. (wikipedia.org)
epithelium
- They arise from the cells along the pituitary stalk, specifically from nests of odontogenic (tooth-forming) epithelium within the suprasellar/diencephalic region and, therefore, contain deposits of calcium that are evident on an x-ray. (wikipedia.org)
Gene
- Consequently, alterations of the gene represent a candidate pathogenetic mechanism of pituitary tumorigenesis especially when considered in terms of interactions with other proteins, growth factors, oncogenes play a rule in tumorigenesis. (wikipedia.org)
multiple
- At the other end of this spectrum, detection of the myeloid protein indicates the presence of a hematological malignancy, i.e. multiple myeloma, Waldenström's macroglobulinemia, or other B cell-associated neoplasm, that derives stepwise from its MGUS precursors. (wikipedia.org)
function
- Assessment of pituitary function should be supervised by an endocrinologist (e.g. (pedsoncologyeducation.com)
treatment
- FDA grants approval to tagraxofusp-erzs (Elzonris), a first treatment for blastic plasmacytoid dentritic cell neoplasm and the first therapy to target CD123. (oncologynurseadvisor.com)
region
- Temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. (oncologynurseadvisor.com)
result
- This elevation occurs as a result of the compression of the pituitary stalk, which interferes with the brain's control of prolactin production. (wikipedia.org)
surgery
- His past medical history was significant for non-functional pituitary macroadenoma and medullary thyroid carcinoma and he had received a total thyroidectomy and a transsphenoidal surgery several years ago. (biomedcentral.com)