- adenomas
- During the last decades Clinics of Neurosurgery and Otorhinolaryngology of the Medicomilitary Academy gained a rather profound experience in surgery of pituitary adenomas, using a transnasosphenoidal approach. (neva.ru)
- There are absolute and particular indications for surgical treatment of different pituitary adenomas. (neva.ru)
- Pituitary adenomas can cause compression of optic nerves and chiasm, which will lead to damage of vision. (clinicaltrials.gov)
- This study aims to evaluate the predictive factors for recovery of vision in patients with pituitary adenomas following trans-sphenoidal surgery. (clinicaltrials.gov)
- Patients with pituitary adenomas at Huashan Hospital will be screened. (clinicaltrials.gov)
- Pituitary adenomas is a very common disease, but the cause and genetics hasn't been identified. (clinicaltrials.gov)
- The investigators are going to use genome-wide association study to identify genes that may be related to pituitary adenomas. (clinicaltrials.gov)
- Patients diagnosed with pituitary adenomas and healthy controls will be included. (clinicaltrials.gov)
- Preoperative imaging identification and localization of adrenocorticotropin hormone (ACTH)-secreting pituitary adenomas is critical for the accurate diagnosis and the successful surgical treatment of Cushing s disease (CD). (clinicaltrials.gov)
- Because ACTH-adenomas are metabolically active compared to the surrounding pituitary gland, (18)F-fludeoxyglucose ((18)F-FDG) positron emission tomography (PET)-imaging in CD patients could be used to detect adenomas not detectable on MR-imaging. (clinicaltrials.gov)
- Moreover, corticotropin-releasing hormone (CRH) can be given to selectively increase the metabolic activity of ACTH-secreting pituitary adenomas to increase the likelihood of their detection and localization by (18)F-FDG PET-imaging. (clinicaltrials.gov)
- MEN1 pituitary tumours are adenomas of anterior cells, typically prolactinomas or growth hormone-secreting. (wikipedia.org)
- MEN1 gene mutations and deletions also play a role in the development of hereditary and a subgroup of sporadic pituitary adenomas and were detected in approximately 5% of sporadic pituitary adenomas. (wikipedia.org)
- Pituitary adenomas are tumors that occur in the pituitary gland, and account for about 15% of intracranial neoplasms. (wikipedia.org)
- Pituitary adenomas are tumors that occur in the pituitary gland. (wikipedia.org)
- Pituitary adenomas are generally divided into three categories dependent upon their biological functioning: benign adenoma, invasive adenoma, and carcinomas. (wikipedia.org)
- Most pituitary adenomas are microadenomas, and have an estimated prevalence of 16.7% (14.4% in autopsy studies and 22.5% in radiologic studies). (wikipedia.org)
- Pituitary macroadenomas are the most common cause of hypopituitarism, and in the majority of cases they are non-secreting adenomas. (wikipedia.org)
- While pituitary adenomas are common, affecting approximately one in 6 of the general population, clinically active pituitary adenomas that require surgical treatment are more rare, affecting approximately one in 1000 of the general population. (wikipedia.org)
- Hormone secreting pituitary adenomas cause one of several forms of hyperpituitarism. (wikipedia.org)
- Various types of headaches are common in patients with pituitary adenomas. (wikipedia.org)
- Various psychiatric manifestations have been associated with pituitary disorders including pituitary adenomas. (wikipedia.org)
- reported a case series of 8 patients with a syndrome of pituitary, parathyroid, and pancreatic islet adenomas. (wikipedia.org)
- Tumors
- This is a Phase 2 open-label, single-treatment group, baseline-controlled study designed to verify product safety, gather data on the percentage of subjects with pituitary tumors with increased uptake of FolateScan in tumors and correlate the immunohistochemical staining findings with the FolateScan images, in subjects with pituitary tumors. (clinicaltrials.gov)
- The purpose of the family study is to investigate the genetic basis for the development of pituitary tumors by assessing the prevalence of pituitary tumors in relatives of probands with the disease as compared to the prevalence in unrelated spouses sharing a similar environment. (clinicaltrials.gov)
- The major purpose of this study is to evaluate the changes of multiple organs in patients with growth hormone-secreting pituitary tumors before and after surgery. (clinicaltrials.gov)
- Large pituitary tumors can paradoxically elevate blood prolactin levels due to the "stalk effect. (wikipedia.org)
- Play media A 1972 study compared neoplasms in "Sprague-Dawley" rats from six different commercial suppliers and found highly significant differences in the incidences of endocrine and mammary tumors. (wikipedia.org)
- gland
- Endoscopic videomonitoring in a transseptal transsphenoidal approach to the pituitary gland is not only possible, but also expedient, as this method permits to visualize main anatomic landmarks of the sphenoid sinus in a panoramic examination of its cavity and to ensure optimum access to the saddle fundus and structures [2, 7, . (neva.ru)
- Cushing s disease can be caused by a tumor of the pituitary gland, a small gland about the size of a pea located at the base of the brain. (clinicaltrials.gov)
- The cure for this type of Cushing s disease is to have surgery that removes the tumor but leaves the pituitary gland alone. (clinicaltrials.gov)
- The MEN1 phenotype is inherited via an autosomal-dominant pattern and is associated with neoplasms of the pituitary gland, the parathyroid gland, and the pancreas (the 3 "P"s). (wikipedia.org)
- An endocrine gland neoplasm is a neoplasm affecting one or more glands of the endocrine system. (wikipedia.org)
- Acromegaly is a syndrome that results when the anterior pituitary gland produces excess growth hormone (GH). (wikipedia.org)
- Findings affecting pituitary function in some JBS patients have included such anomalies as the formation of a glial hamartoma (a neoplasm, or tumor composed of glial cells) on a lobe of the pituitary gland, as well congenital underdevelopment of the anterior pituitary. (wikipedia.org)
- Craniopharyngioma is a type of brain tumor derived from pituitary gland embryonic tissue, that occurs most commonly in children but also in adults in their 50s and 60s. (wikipedia.org)
- Symptoms include: Stunted growth and delayed puberty (in children) General fatigue, loss of muscle mass and tone (in adults) Pituitary insufficiency often occurs to some degree because craniopharyngiomas develop in the area of the pituitary stalk, which can affect the function of the pituitary gland. (wikipedia.org)
- Other reported sites of heterotopic salivary gland tissue are the middle ear, parathyroid glands, thyroid gland, pituitary gland, cerebellar pontine angle, soft tissue medial to sternocleidomastoid, stomach, rectum and vulva. (wikipedia.org)
- Salivary gland neoplasm occurrence within heterotopic salivary gland tissue is rare. (wikipedia.org)
- anterior
- Specific progestin binding in vitro by anterior pituitary and brain tissues of male rats. (biomedsearch.com)
- Growth failure and associated short stature (dwarfism) in JBS can be attributed to growth hormone deficiency caused by diminished anterior pituitary function, with malabsorption of fats playing a subsequent role. (wikipedia.org)
- Rathke's pouch is an embryonic precursor of the anterior pituitary. (wikipedia.org)
- Acromegaly
- Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to acromegaly. (clinicaltrials.gov)
- Approximately 90-95% of acromegaly cases are caused by a pituitary adenoma and it most commonly affects middle aged adults, Acromegly can result in severe disfigurement, serious complicating conditions, and premature death if unchecked. (wikipedia.org)
- parathyroid glands
- In 1903 Erdheim described the case of an acromegalic patient with a pituitary adenoma and three enlarged parathyroid glands. (wikipedia.org)
- hormone
- This occurs due to the absence of a posterior pituitary hormone called antidiuretic hormone (ADH). (wikipedia.org)
- Since a significant number of gastrinomas are associated with MEN involving other hormone producing organs (pancreas, parathyroids, and pituitary), higher levels of C-peptide together with the presence of a gastrinoma suggest that organs besides the stomach may harbor neoplasms. (wikipedia.org)
- stalk
- If originating superior to the optic chiasm, more commonly in a craniopharyngioma of the pituitary stalk, the visual field defect will first appear as bitemporal inferior quadrantanopia, if originating inferior to the optic chiasm the visual field defect will first appear as bitemporal superior quadrantanopia. (wikipedia.org)
- They arise from the cells along the pituitary stalk, specifically from nests of odontogenic (tooth-forming) epithelium within the suprasellar/diencephalic region and, therefore, contain deposits of calcium that are evident on an x-ray. (wikipedia.org)
- This elevation occurs as a result of the compression of the pituitary stalk, which interferes with the brain's control of prolactin production. (wikipedia.org)
- tumorigenesis
- Consequently, alterations of the gene represent a candidate pathogenetic mechanism of pituitary tumorigenesis especially when considered in terms of interactions with other proteins, growth factors, oncogenes play a rule in tumorigenesis. (wikipedia.org)
- tissue
- Obtained results are indicative of such main advantages of the method, as a panoramic view of the sphenoid sinus cavity, precise differentiation of neoplastic and intact tissue of the pituitary body, early diagnosis and elimination of liquorrhea. (neva.ru)
- psychiatric
- As early as 1916 he described neurologic and psychiatric sequelae of pituitary neoplasms. (wikipedia.org)
- craniopharyngioma
- Craniopharyngioma is a rare, usually suprasellar neoplasm, which may be cystic, that develops from nests of epithelium derived from Rathke's pouch. (wikipedia.org)
- patients
- Unfortunately, over 40 percent of CD patients do not have a visible pituitary adenoma on magnetic resonance (MR)-imaging (the most sensitive imaging modality for ACTH-positive adenoma detection and localization). (clinicaltrials.gov)
- symptoms
- Also, a pituitary adenoma can cause symptoms of increased intracranial pressure. (wikipedia.org)
- incidental
- A majority of pituitary microadenomas often remain undiagnosed and those that are diagnosed are often found as an incidental finding, and are referred to as incidentalomas. (wikipedia.org)
- surgery
- The major purpose of this study is to evaluate the changes before and after the pituitary surgery. (clinicaltrials.gov)
- patient
- A patient with pituitary adenoma may present with visual field defects, classically bitemporal hemianopsia. (wikipedia.org)
- include
- Examples include: Adrenal tumor Pituitary adenoma The most common form is thyroid cancer. (wikipedia.org)
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