• 4) Picibanil (Chugai Pharmaceutical Co., Tokyo, Japan) is a drug that has been used for anti-cancer immuno- therapy. (kjhno.org)
  • TARA-002 was developed from the same master cell bank of genetically distinct group A Streptococcus pyogenes as OK-432, a broad immunopotentiator marketed as Picibanil ® in Japan and Taiwan by Chugai Pharmaceutical Co., Ltd. (protaratx.com)
  • Picibanil also called OK - 432, is a mixture of group A streptococcus with anti-neoplastic properties used in treatment of cystic hygroma (lymphangiomas). (wikipedia.org)
  • Nowadays, sclerotherapy using picibanil has been performed instead of invasive surgical treatment, and studies are reporting safe and effective outcomes. (kjhno.org)
  • Picibanil sclerotheraphy can be considered as the primary treatment of plunging ranula for patients who refuse surgery under general anaesthesia. (kjhno.org)
  • reported outstanding effects of picibanil for the treatment of lymphatic malformation. (kjhno.org)
  • 6) Ranulas are thin membrane-enclosed cystic masses that are structurally similar to lymphatic malformation, and studies have reported safe and effective results with picibanil as a treatment for ranulas. (kjhno.org)
  • The medical records of 25 patients, who were diagnosed with plunging ranula and received picibanil sclerotherapy as the primary treatment by a single surgeon (HAS) in the National Health Insurance Service Ilsan hospital from January 2010 to December 2019, were retrospectively analyzed. (kjhno.org)
  • The effectiveness of intralesional sclerotherapy of lymphangioma with OK-432 (Picibanil) has been proved in several clinical studies. (medigraphic.com)
  • The aim of our study was to review the effectiveness of sclerotherapy of benign tongue cysts with Picibanil as an alternative method to surgical excision. (medigraphic.com)
  • No significant complications after sclerotherapy with Picibanil was observed. (medigraphic.com)
  • The therapeutic effect of OK-432 (picibanil) sclerotherapy for benign neck cysts. (medscape.com)
  • OK-432 (picibanil) is an inactivated preparation of Streptococcus pyogenes that causes pleurodesis by inducing a strong inflammatory response. (e-cep.org)
  • A prospective observational study was carried out to assess the effects of Picibanil on tongue cysts. (medigraphic.com)
  • Twelve of them had tongue cysts which were treated with intralesional application of Picibanil with a dose ranging from 0.01 mg/mL to 0.03 mg/mL. (medigraphic.com)
  • It is called ' OK-432' or Picibanil and it is meant for treatment of Lymphatic Malformation macro-cystic cysts. (zacsattack.com)
  • Picibanil also called OK - 432, is a mixture of group A streptococcus with anti-neoplastic properties used in treatment of cystic hygroma (lymphangiomas). (wikipedia.org)
  • 14. Effects of sequential and combined immuno-endocrine therapies using OK-432 (Picibanil) and tamoxifen on the growth of 7,12-dimethylbenz [alpha] anthracene-induced rat mammary carcinoma. (nih.gov)