PhospholipidsLipidsPhosphatidylinositolPresence of phosphatidylglycerolSynthesis of PhosphatidylglycerolPhosphatidylcholine and phosphatidylglycerolLipidSynthasePhospholipidSphingomyelinPhosphatePhosphatidic acidRatioConsistsCalciumFattyFormPhosphatidylethanolaminePhosphatidylserineSynthesisPhosphatidylcholinesCardiolipin synthaseDiphosphatidylglycerolMembraneSurfactantMaturityCompositionDetectionMakesLevelStructure
Phospholipids7
- The major surfactant deficiency in premature infants relates to the lack of phosphatidylglycerol, even though it comprises less than 5% of pulmonary surfactant phospholipids. (wikipedia.org)
- Phosphatidylglycerol (PG) is typical of many phospholipids in that it contains two acyl chains esterified to a glycerol, which in turn is bonded to a headgroup structure that contains net charges. (tonyajoy.com)
- The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. (planteome.org)
- This strain produced triglycerides (TG) as well as four common phospholipids: phosphatidylethanolamine (PE), phosphatidylglycerol (PG), cardiolipin (CL) and lysocardiolipin (LCL). (nature.com)
- Phosphatidylglycerol (PG) makes up 5-20% of the phospholipids of Escherichia coli and is essential for growth in wild-type cells. (duke.edu)
- The predominant phospholipids were phosphatidylethanolamine, phosphatidylglycerol and cardiolipin. (microbiologyresearch.org)
- Figure 1 shows that RecA binds to the anionic phospholipids phosphatidylglycerol (PG) and cardiolipin (CL) with an apparent Kd of 7.0 and 2.4 M, respectively. (wisc.edu)
Lipids4
- While CL increases, the two predominant lipids phosphatidylglycerol (PG) and phosphatidylethanolamine (PE) of the exponential growth phase decrease as B. subtilis enters stationary phase 6 . (nature.com)
- The major polar lipids of strain YSS-7(T) were phosphatidylcholine, phosphatidylglycerol, an unidentified aminolipid and an unidentified lipid. (nih.gov)
- Diphosphatidylglycerol, phosphatidylethanolamine, phosphatidylcholine and phosphatidylglycerol are the major polar lipids. (microbiologyresearch.org)
- With some fine tuning, the scientists created a cell in which all phosphatidylglycerol, the lipids which form the basic bilayer of the bacterial membrane, were replaced by their archaeal equivalent (archaetidylglycerol). (rug.nl)
Phosphatidylinositol2
- The presence of phosphatidylglycerol (PG) and phosphatidylinositol are associated with fetal lung maturity as they help maintain alveolar stability. (medicalalgorithms.com)
- The resulting CDP-diacylglycerol can be utilized immediately for the synthesis of phosphatidylglycerol (PG), and thence cardiolipin (CL), and of phosphatidylinositol (PI). (ymdb.ca)
Presence of phosphatidylglycerol1
- 2:1 or presence of phosphatidylglycerol indicates maturity. (msdmanuals.com)
Synthesis of Phosphatidylglycerol1
- In Vivo and in Vitro Synthesis of Phosphatidylglycerol by an Escherichia coli Cardiolipin Synthase. (duke.edu)
Phosphatidylcholine and phosphatidylglycerol1
- CCl4 at 5microl/ml also inhibited incorporation of labeled glycerol and glucose into surfactant phosphatidylcholine and phosphatidylglycerol. (cdc.gov)
Lipid3
- Phosphatidylglycerol is a glycerophospholipid found in pulmonary surfactant and in the plasma membrane where it directly activates lipid-gated ion channels. (wikipedia.org)
- In this review, evidence from a range of studies about the lipid phosphatidylglycerol is considered. (tonyajoy.com)
- Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. (avivasysbio.com)
Synthase2
- Phosphatidylglycerol combines with CDP-DAG forming cardiolipin releasing CMP by the action of cardiolipin synthase. (wikipedia.org)
- In eukaryotic mitochondria phosphatidylglycerol is converted to cardiolipin by reacting with a molecule of cytidine diphosphate diglyceride in a reaction catalyzed by cardiolipin synthase (Hostetler KY, van den Bosch H, van Deenen LL. (wikipedia.org)
Phospholipid1
- Is Phosphatidylglycerol a phospholipid? (tonyajoy.com)
Sphingomyelin1
- Biochemical tests meas- ure components of the surfactant and in- clude the lecithin/sphingomyelin (L/S) ratio and phosphatidylglycerol measure- ments. (tonyajoy.com)
Phosphate3
- The general structure of phosphatidylglycerol consists of a L-glycerol 3-phosphate backbone ester-bonded to either saturated or unsaturated fatty acids on carbons 1 and 2. (wikipedia.org)
- Glycerol-3-phosphate reacts with CDP-diacylglycerol to form phosphatidylglycerol phosphate, while CMP is released. (wikipedia.org)
- The phosphate group is hydrolysed forming phosphatidylglycerol. (wikipedia.org)
Phosphatidic acid1
- Phosphatidylglycerol is formed from phosphatidic acid by a sequence of enzymatic reactions that proceeds via the intermediate, cytidine diphosphate diacylglycerol (CDP-diacylglycerol). (hmdb.ca)
Ratio1
- What is LS ratio and Phosphatidylglycerol? (tonyajoy.com)
Consists1
- Consists of a mixture of phosphatidylcholine, cholesterol, and distearoyl phosphatidylglycerol that arrange into amphotericin B-containing unilamellar vesicles in aqueous media. (medscape.com)
Calcium2
- Its antibacterial activity requires calcium and correlates with the content of phosphatidylglycerol in the target membrane. (uwaterloo.ca)
- Calcium dependent phospholipase A2 activity in the mixed micelles of 1-palmitoyl-2-oleoyl-phosphatidylglycerol and cholate was measured in sera of 39 patients with Crohn's disease, 40 patients with ulcerative colitis, and 40 healthy controls. (bmj.com)
Fatty1
- As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. (hmdb.ca)
Form1
- Two phosphatidylglycerols form cardiolipin, the constituent molecule of the mitochondrial inner membrane. (wikipedia.org)
Phosphatidylethanolamine5
- While the first optimization was based on three phosphatidylcholines (PCs), this work extends the validation and parametrization to more lipids including PC, phosphatidylethanolamine (PE), phosphatidylglycerol (PG), and ether lipids. (nih.gov)
- The phospholipid pattern was found to consist of diphosphatidylglycerol, phosphatidylglycerol and phosphatidylethanolamine. (springer.com)
- Strain SK 55 T , Sporosarcina macmurdoensis and Sporosarcina ureae , the type species of the genus, had some polar lipids in common (diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine, a phospholipid and an unknown lipid). (microbiologyresearch.org)
- E. coli membranes consist of ~5% cardiolipin (CL), 20-25% phosphatidylglycerol (PG), and 70-80% phosphatidylethanolamine (PE) as well as smaller amounts of phosphatidylserine (PS). (ymdb.ca)
- Also, OE of FAX1 and ABCA9 affected membrane lipid composition in developing pods, especially on phosphatidylcholine, phosphatidylethanolamine, and phosphatidylglycerol. (biomedcentral.com)
Phosphatidylserine1
- Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner. (creativebiomart.net)
Synthesis2
- 2019. Synthesis of phosphatidylglycerol receptor: precursor preparation -- In Proceedings: 19th Annual Undergraduate Research and Creative Activity Forum. (wichita.edu)
- In Vivo and in Vitro Synthesis of Phosphatidylglycerol by an Escherichia coli Cardiolipin Synthase. (duke.edu)
Phosphatidylcholines1
- We found that SWCNTs selectively adsorbed two types of the most abundant surfactant phospholipids: phosphatidylcholines (PC) and phosphatidylglycerols (PG). (cdc.gov)
Cardiolipin synthase2
- Phosphatidylglycerol combines with CDP-DAG forming cardiolipin releasing CMP by the action of cardiolipin synthase. (wikipedia.org)
- In eukaryotic mitochondria phosphatidylglycerol is converted to cardiolipin by reacting with a molecule of cytidine diphosphate diglyceride in a reaction catalyzed by cardiolipin synthase (Hostetler KY, van den Bosch H, van Deenen LL. (wikipedia.org)
Diphosphatidylglycerol1
- In prokaryotes such as E. coli, the enzyme known as diphosphatidylglycerol synthase catalyses the transfer of the phosphatidyl moiety of one phosphatidylglycerol to the free 3'-hydroxyl group of another, with the elimination of one molecule of glycerol. (ymdb.ca)
Membrane4
- Two phosphatidylglycerols form cardiolipin, the constituent molecule of the mitochondrial inner membrane. (wikipedia.org)
- Antimicrobial peptides target the bacterial plasma membrane by first binding to phosphatidylglycerol (PG) via Columbic interaction, followed by insertion into the membrane and killing the bacterial cell. (wichita.edu)
- This activity, which can account for daptomycin's bactericidal effect, correlates with the level of phosphatidylglycerol (PG) in the membrane. (uwaterloo.ca)
- hydrophilic residues are colored in light-steel-blue , hydrophobic residues are in coral and glycines are in magenta ) with two different membrane models including POPC (1-palmitoyl-oleoyl-glycero-phosphocholine) and POPG (Palmitoyl-oleoyl-phosphatidylglycerol). (proteopedia.org)
Surfactant2
- Phosphatidylglycerol is thought to be important in spreading of surfactant over the Type I cellular surface area. (wikipedia.org)
- The major surfactant deficiency in premature infants relates to the lack of phosphatidylglycerol, even though it comprises less than 5% of pulmonary surfactant phospholipids. (wikipedia.org)
Maturity2
- 2:1 or presence of phosphatidylglycerol indicates maturity. (msdmanuals.com)
- If premature delivery is anticipated with either oligohydramnios or polyhydramnios, the amniotic fluid lamellar body count, lecithin-sphingomyelin (L:S) ratio, and phosphatidylglycerol (PG) concentration are helpful in determining the maturity of the fetal lungs and, therefore, in assessing the likelihood of respiratory distress syndrome. (medscape.com)
Composition2
- Creative Proteomics provides you with efficient and accurate qualitative and quantitative detection services and the fatty acid composition analysis of phosphatidylglycerol through advanced chromatography and mass spectrometry platforms. (creative-proteomics.com)
- As a result, phosphatidylglycerol remodeling is impaired, which likely alters the composition of cardiolipin. (medlineplus.gov)
Detection2
- If you have any questions about our phosphatidylglycerol detection service, please contact us . (creative-proteomics.com)
- A commercially available test for the rapid detection of phosphatidylglycerol (PG) is another option. (aacc.org)
Makes1
- Phosphatidylglycerol (PG) makes up 5-20% of the phospholipids of Escherichia coli and is essential for growth in wild-type cells. (duke.edu)
Level1
- 8. Lipidome-wide characterization of phosphatidylinositols and phosphatidylglycerols on CC location level. (nih.gov)
Structure1
- The general structure of phosphatidylglycerol consists of a L-glycerol 3-phosphate backbone ester-bonded to either saturated or unsaturated fatty acids on carbons 1 and 2. (wikipedia.org)