• engulfs
  • In cell biology, phagocytosis (from Ancient Greek φαγεῖν (phagein) , meaning 'to devour', κύτος, (kytos) , meaning 'cell', and -osis, meaning 'process') is the process by which a cell-often a phagocyte or a protist-engulfs a solid particle to form an internal compartment known as a phagosome. (wikipedia.org)
  • Phagocytosis engulfs whole particles, which are later broken down by enzymes, such as cathepsins, and absorbed into the cells. (wikipedia.org)
  • monocytes
  • In this paper we re-examine the roles of particle-bound IgG and C3 in phagocytosis of sheep erythrocytes (E) by monolayers of purified human monocytes and polymorphonuclear leukocytes (PMN). (rupress.org)
  • soluble
  • When activated, microglia undergo morphological changes to ameboid, proliferate, migrate toward injured areas, and release many soluble factors and phagocytosis of foreign substances or unwanted self-debris. (hindawi.com)
  • Phagoptosis is normally caused by: the cell exposing on its surface so-called "eat-me" signals, and/or the cell no longer exposing "don't-eat-me" signals and/or the cell being opsonised i.e. binding soluble proteins that tag the cell for phagocytosis. (wikipedia.org)
  • Thus
  • Thus, opsonization of the particle with C3 can be a necessary condition for particle ingestion, although by itself C3 does not trigger phagocytosis. (rupress.org)
  • thus pharmacological potentiation of phagocytosis has a medical potential in treatment of certain forms of autoimmune disorders. (wikipedia.org)
  • proteins
  • Yersinia inhibits phagocytosis through the concerted actions of several effector proteins, including YopE which acts as a RhoGAP and inhibits Rac-dependent actin polymerization. (wikipedia.org)
  • role
  • Mitchell R.H., Gander G.W., Goodale F. (1976) The Role of Phagocytosis in the Production of Endogenous Pyrogen by Polymorphonuclear Leukocytes. (springer.com)
  • Type
  • Phagoptosis is a type of cell death caused by the cell being phagocytosed (i.e. eaten) by another cell, and therefore this form of cell death is prevented by blocking phagocytosis. (wikipedia.org)
  • work
  • In 1954, Stähelin successfully applied for a 12-month postdoctoral fellowship sponsored by the Swiss National Foundation (SNF) to work on a project on phagocytosis inspired by Emanuel Suter (then at Harvard, later second Dean of the University of Florida Medical School). (wikipedia.org)
  • research
  • Continuing our research on Mycobacteria kansasii phagocytosis inhibition, we have examined in that context three series of peptides derived from the RGDVY and GRGD sequences. (sigmaaldrich.com)