Perfusion. Medical search. Frequent questions

Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, usually referring to the delivery of blood to a capillary bed in tissue. (wikipedia.org)
Perfusion is measured as the rate at which blood is delivered to tissue, or volume of blood per unit time (blood flow) per unit tissue mass. (wikipedia.org)
However, this terminology can be a source of confusion since both cardiac output and the symbol Q refer to flow (volume per unit time, for example, L/min), whereas perfusion is measured as flow per unit tissue mass (mL/(min·g)).[citation needed] Microspheres that are labeled with radioactive isotopes have been widely used since the 1960s. (wikipedia.org)
Tissue perfusion can be affected by physiology or disease. (snmjournals.org)
Real-time anatomic display of tissue perfusion, vascularity and ischemia in the tissue of interests during surgery is critical and necessary for improvements in technical and cognitive decisions. (sages.org)
Tissue perfusion was imaged and monitored over the course of time up to an hour. (sages.org)
Figure 2 shows an RGB image of the target bowel tissue regions acquired using the hyperspectral color compsensation from the same hyperspectral imager, while Figure 3 shows the resulting heatmap of the tissue perfusion image where the higher oxygen saturation levels are in yellow and lower levels are in blue. (sages.org)
Although several markers for measuring global tissue perfusion are available, there are currently no practical measurements of capillary microvascular perfusion in horses with hypovolaemia. (ivis.org)
Our aim was to evaluate whether increasing iodine concentration, at a constant total iodine dose, resulted in better brain tissue opacification in patients with acute stroke symptoms during their evaluation by first-pass CT perfusion (CTP). (ajnr.org)
Functional maps of tissue perfusion are then constructed from the acquired temporal data to visualize blood flow, blood volume, and mean transit time. (ajnr.org)
Microcirculatory tissue perfusion during general anaesthesia and noncardiac surgery: An observational study using incident dark field imaging with automated video analysis. (iasp-pain.org)
Automated analysis allows quantifying microcirculatory tissue perfusion variables - including tissue red blood cell perfusion (tRBCp), a functional variable integrating microcirculatory convection and diffusion capacities. (iasp-pain.org)
Perfusion" is defined as the steady-state delivery of blood to an element of tissue (ie, capillary blood flow). (ajnr.org)
Research into the effects of surgical ligation of the ductus arteriosus (DA) on regional tissue perfusion is limited. (bmj.com)
Visual assessment of vessels, blood flow and related tissue perfusion. (nih.gov)

Develop cardiovascular perfusion competence (skills, knowledge, behaviors) that are portable across national and international healthcare and professional and professional environments. (ltu.edu)
Gain expertise in medical, biological, and physical sciences in relation to cardiovascular perfusion. (ltu.edu)
Cultivate a commitment to the enhancement of the cardiovascular perfusion profession. (ltu.edu)
It also provides the appropriate depth and breadth of knowledge, applied, specialized preparation in critical thinking and scholarly research, problem-solving and analysis, communications, leadership, professional capacity, and autonomy in the field of cardiovascular perfusion. (ltu.edu)
Our Master of Science in Cardiovascular Perfusion program is intended for students with a bachelor's degree in a field other than cardiovascular perfusion. (rush.edu)
The program curriculum provides the knowledge, clinical experiences and opportunity for you to achieve competence in the practice of cardiovascular perfusion. (rush.edu)

Isolated hypoxic hepatic perfusion with melphalan in patients with irresectable ocular melanoma metastases. (nih.gov)
Determine response rate, duration of response, and patterns of recurrence in patients with primary or metastatic, unresectable cancers of the liver after treatment with isolated hepatic perfusion with melphalan. (knowcancer.com)
Remaining patients receive isolated hepatic perfusion with melphalan. (knowcancer.com)

Software is has been developed and available for licensing that fully automates image processing for the quantification of myocardial blood flow (MBF) pixel maps from firstpass contrast-enhanced cardiac magnetic resonance (CMR) perfusion images. (nih.gov)

In planar technique, the computer provides a 2-dimensional myocardial perfusion image. (medscape.com)

Perfusion of various tissues can be readily measured in vivo with nuclear medicine methods which are mainly positron emission tomography (PET) and single photon emission computed tomography (SPECT). (wikipedia.org)
The summed stress score includes fixed and reversible perfusion defects that appear on SPECT images and is an established predictor of cardiovascular outcomes, including MI, according to the authors. (medscape.com)
However, in patients who have SPECT MPI performed, attention should be paid to those patients with perfusion characteristics associated with a high risk of sudden cardiac death," they conclude. (medscape.com)
Conventional single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) evaluates the presence, extent, and degree of myocardial ischemia or infarction (ie, flow-limiting defects). (medscape.com)
ECG-gated SPECT images allow for the assessment of the global left ventricular ejection fraction (LVEF), regional wall motion, and regional wall thickening at rest in patients with documented stress-induced wall motion and perfusion abnormalities. (medscape.com)
The aim of this study was to investigate the functional changes in the follow-up of patients with DCM undergoing PLV using electrocardiographically triggered perfusion SPECT (gated SPECT). (nih.gov)
In this highly selected DCM patient group, gated perfusion SPECT assessed early responses in volumes and EF after PLV-MVR. (nih.gov)
Occipital lobe perfusion defects have been identified on regional cerebral blood flow (rCBF) SPECT scans of adolescent children and young adults with major depressive disorder (MDD). (snmjournals.org)
Occipital lobe (Brodmann's areas 18 and 19) perfusion defects have been identified on 99m Tc-hexamethylpropyleneamine oxime regional cerebral blood flow (rCBF) SPECT scans of adolescent children and young adults with major depressive disorder (MDD) diagnosed by the criteria of the Diagnostic and Statistical Manual of Mental Disorders , third edition ( 1 , 2 ). (snmjournals.org)

A normothermic ex vivo organ perfusion delivery method for cardiac transplantation gene therapy. (nih.gov)
citation needed] In equations, the symbol Q is sometimes used to represent perfusion when referring to cardiac output. (wikipedia.org)
adding perfusion data to the clinical history and LVEF increased the model's discrimination for sudden cardiac death. (medscape.com)
The study also recorded the summed difference score, the sum of the differences between the stress and rest perfusion scores, indicating reversible defects, but the summed difference score was not predictive of sudden cardiac death. (medscape.com)
Previous data suggest that DA closure may result in impaired cerebral perfusion 1 because of alterations in pulmonary mechanics or cardiac function. (bmj.com)

Brain perfusion measurements with pseudo-continuous arterial spin labeling were analyzed using the standard Oxford ASL pipeline. (wellnessresources.com)
1 Arterial spin-labeling is a newer perfusion MR imaging technique that uses magnetically labeled arterial blood water as a flow tracer rather than a GBCA to characterize perfusion. (ajnr.org)
2]. Laminar perfusion imaging with zoomed arterial spin labeling at 7 Tesla . (nih.gov)

As expected, higher perfusion rate would provide high oxygen level for the cells and, smaller spheroids with a diameter of 100 μm were at the low risk of hypoxic conditions due to short diffusive oxygen penetration depth. (frontiersin.org)
real time perfusion imaging: quantitative measurement, mechanical index 0.12) showed segmental heterogeneous segmental perfusion (higher perfusion in the middle septal segment than in the lateral wall) and transmural homogeneous perfusion (fig 2). (bmj.com)

Bridge to Life is a leading supplier of preservation solutions globally with a focus on innovation in organ preservation and machine perfusion. (ilts.org)
The SIG group (Machine perfusion and DCD) invites everyone to participate in two webinars on dynamic preservation techniques to memorise our colleague and friend Paolo Muiesan. (ilts.org)
The SIG group (Machine perfusion and DCD) invites everyone to participate in two webinars on. (ilts.org)

This study aims to model language vs. domain-general performance in PPA on frontal, parietal, and temporal brain areas based on their perfusion. (easychair.org)
To investigate CBF in frontal, parietal, and temporal brain areas, we conducted perfusion analysis in 38 patients with PPA (13 with the logopenic PPA variant, 19 with the non-fluent PPA variant, 6 with the semantic PPA variant). (easychair.org)
The previously proposed time-extended DCE protocol, called Snaps, provides additional temporal perfusion information at the expense of a minimal extension of the conventional DCE acquisition time. (degruyter.com)
A significant interaction effect between group and time was found for right superior temporal gyrus (STG) perfusion, driven by an increase in the IG and a decrease in the CG. (wellnessresources.com)
However, the clinical application of perfusion MRI has been (i.e., high temporal resolution). (nih.gov)
In the following we will limited by a number of factors, including a relatively poor show how recent methodological developments can in- spatial resolution, limited volume coverage, and low signal- crease the temporal and spatial resolution of perfusion to-noise ratio (SNR). (nih.gov)

Tests verifying that adequate perfusion exists are a part of a patient's assessment process that are performed by medical or emergency personnel. (wikipedia.org)
Images taken during dynamic exercise or pharmacologically induced stress (using vasodilators such as adenosine or a beta-agonist such as dobutamine) and rest injections enable independent assessment of myocardial perfusion and viability. (medscape.com)
Orthogonal polarisation spectral (OPS) imaging allows assessment of capillary microvascular perfusion by visualisation of mucosal blood flow. (ivis.org)

This study aims to examine a time-extended dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) protocol and report a comparative study with three different pharmacokinetic (PK) models, for accurate determination of subtle blood-brain barrier (BBB) disruption in patients with multiple sclerosis (MS). This time-extended DCE-MRI perfusion protocol, called Snaps, was applied on 24 active demyelinating lesions of 12 MS patients. (degruyter.com)

[ 11 ] and the first application of thallium-201 myocardial perfusion imaging by Elliot Lebowitz. (medscape.com)
To develop the methodology for total-body perfusion imaging, a pilot study using [ 11 C]-butanol on the uEXPLORER total-body PET/CT scanner was conducted. (snmjournals.org)
Perfusion imaging using PET has been clinically used to assess single-organ, flow-related diseases such as cerebral stroke and myocardial ischemia ( 1 , 2 ). (snmjournals.org)
This is the first description of a case of isolated non-compaction of the left ventricular myocardium, involving a 52 year old woman presenting with progressive heart failure, with analysis of myocardial perfusion by contrast echocardiography in comparison with magnetic resonance imaging. (bmj.com)
First-pass CT perfusion (CTP) has become an important imaging tool that is used routinely in the triage of patients with acute stroke. (ajnr.org)
MR perfusion imaging is becoming an increasingly common means of evaluating a variety of cerebral pathologies, including tumors and ischemia. (ajnr.org)
In particular, there has been great interest in the use of MR perfusion imaging for both assessing brain tumor grade and for monitoring for tumor recurrence in previously treated patients. (ajnr.org)
Of the various techniques devised for evaluating cerebral perfusion imaging, the dynamic susceptibility contrast method has been employed most widely among clinical MR imaging practitioners. (ajnr.org)
However, when implementing DSC MR perfusion imaging in a contemporary radiology practice, a neuroradiologist is confronted with a large number of decisions. (ajnr.org)
In an effort to provide guidance to neuroradiologists struggling to implement DSC perfusion imaging in their MR imaging practice, the Clinical Practice Committee of the American Society of Functional Neuroradiology has provided the following recommendations. (ajnr.org)
While the ASFNR acknowledges that alternate means of carrying out DSC perfusion imaging may yield clinically acceptable results, the following recommendations should provide a framework for achieving routine success in this complicated-but-rewarding aspect of neuroradiology MR imaging practice. (ajnr.org)
With MR imaging, the use of exogenous, intravascular, nondiffusible contrast agents such as gadolinium-based contrast agents (GBCA) can allow estimation of quantitative cerebral perfusion parameters by emphasizing either the agent's susceptibility effects through T2* or T2-weighted dynamic susceptibility contrast-enhanced MR imaging or its T1 relaxivity properties through T1-weighted dynamic contrast-enhanced MR imaging (DCE-MRI). (ajnr.org)
As a demonstration, we ob- quate SNR, therefore, ASL requires extensive signal av- tained DSC and ASL perfusion images at 3.0 T and 7.0 T with multichannel RF coils and parallel imaging, which eraging, which leads to long measurement times (typi- allowed us to obtain high-quality images with in-plane cally on the order of 5-10 minutes). (nih.gov)
The system removes the need for laborious manual quantitative CMR perfusion pixel map processing and can process prospective and retrospective studies acquired from various imaging protocols. (nih.gov)

With the advent of total-body PET, quantitative measurement of perfusion across the entire body is possible. (snmjournals.org)

The Snaps protocol achieved triple the window time of perfusion observation by extending the magnetic resonance acquisition time by less than 2 min on average for all patients. (degruyter.com)

Two groups of patients were identified: 8 with significant posterior flow deficits in the occipital cortex (Brodmann's areas 18 and 19), usually symmetric, and best visualized on paramedian sagittal sections, and 13 without obvious occipital perfusion deficits but with anterior rCBF deficits in a pattern often described in the literature, attaining statistical significance in the right frontal region. (snmjournals.org)

To present ongoing and planned clinical trials on the role of in- and ex-situ perfusion techniques in liver transplantation. (ilts.org)

Microvascular perfusion was determined using standardised methods from OPS recordings including proportion of perfused vessels (PPV), functional capillary density (FCD), microvascular flow index (MFI) and vessel density (VD). (ivis.org)
Methods Consecutive stroke patients who were eligible for revascularisation therapy underwent serial diffusion-perfusion MRI. (bmj.com)

Experts with the use of perfusion technology discuss various challenges with clinical trials. (ilts.org)
One of early with the field strength, while at the same time the the main factors limiting the widespread clinical appli- labeling efficiency of ASL and the susceptibility effects cation of perfusion MRI is its relatively poor spatial of DSC are increased at higher field strength. (nih.gov)

Perfusion may also refer to fixation via perfusion, used in histological studies. (wikipedia.org)

The perfusion index increases after successful interscalene nerve blockade and may be used as an indicator for successful block placement in awake patients. (nih.gov)
For PVD patients, local changes in perfusion were investigated and correlated with patient medical history. (snmjournals.org)
Isolated hepatic perfusion, open or percutaneous, allows high doses of cytotoxic chemotherapy to be delivered directly to the liver while minimizing systemic exposure, and has emerged as a viable treatment options for these complex patients. (nih.gov)
A phase I-II study of isolated hepatic perfusion using melphalan with or without tumor necrosis factor for patients with ocular melanoma metastatic to liver. (nih.gov)
age range, 11-16 y) was found not to have posterior defects, but some patients showed evidence of the type of frontal perfusion defects that the literature has described. (snmjournals.org)

Background: The use of tumour necrosis factor (TNF) α in isolated limb perfusion (ILP) for in-transit melanoma metastasis is not uniformly accepted. (eur.nl)

In this paper, a perfusion-based three dimensional (3D) bioreactor comprising encapsulated human liver hepatocellular carcinoma (HepG2) spheroids are analyzed. (frontiersin.org)
Perfusion processes are attractive for these products because once a steady state has been achieved, cell-culture media containing the product is removed from the bioreactor (along with enough cells to account for cell doubling so that a consistent cell count is maintained) and replaced with fresh media on a continual basis. (biopharminternational.com)
Perfusion processes also can offer significantly higher productivities in grams/L of bioreactor working volume per day, enabling the use of smaller, single-use bioreactors and reducing capital expenditures. (biopharminternational.com)

age range, 11-18 y) was found to have occipital perfusion defects on interpretation of scans. (snmjournals.org)

Perfusion increases in the right STG, in the ventral striatum, and in primary motor areas were significantly associated with increases in maximum oxygen uptake (VO2max). (wellnessresources.com)
Alternating tangential flow perfusion technology was implemented and challenges of oxygen delivery and carbon dioxide accumulation were addressed. (confex.com)
Given the importance of oxygen to the brain, you can think of perfusion levels, measured by fMRI, as a stand-in measure for neural activity. (nih.gov)
Transcutaneous partial pressure of oxygen (TcPO2), microcirculatory blood perfusion (MBP), and alpha- and beta-band power were monitored at the beginning of and during the test. (bvsalud.org)

This study more objectively compared choroidal perfusion parameters in a group with non-neovascular AMD to an unaffected age matched control group. (bmj.com)

Since capsules wall acts as a diffusion barrier for nutrients and growth factors, employing the microcapsules in a perfusion chip will facilitate the cell access to nutrients and growth factors required for MSCs differentiation. (aiche.org)
Although reperfusion is the deciding factor with respect to this dramatic response to revascularisation therapy, the influence of pre- and post-treatment diffusion-perfusion status on the speed and degree of recovery are unknown. (bmj.com)
The relationship of diffusion and perfusion lesion indices with the speed and degree of recovery were evaluated. (bmj.com)

This method was developed to evaluate myocardial perfusion and viability and is applied both at rest and after exercise or pharmacologic stress to assess inducible ischemia due to flow-limiting coronary stenoses. (medscape.com)

Perfusion culture of SVF-cells reproducibly promoted in vitro the early formation of a capillary-like network, embedded within an ECM backbone, and the release of numerous pro-angiogenic factors. (nature.com)

citation needed] Malperfusion can refer to any type of incorrect perfusion though it usually refers to hypoperfusion. (wikipedia.org)
Overperfusion and underperfusion should not be confused with hypoperfusion and hyperperfusion, which relate to the perfusion level relative to a tissue's current need to meet its metabolic needs. (wikipedia.org)
sometimes the latter term refers to zero perfusion, but often it refers to any hypoperfusion that is bad enough to cause necrosis. (wikipedia.org)
Cerebral hypoperfusion by perfusion-weighted MRI in normal-appearing white matter in primary neuropsychiatric lupus erythematosus' by Papadaki et al' by Wallace. (bmj.com)
Cerebral hypoperfusion by perfusion-weighted MRI in normal appearing white matter in primary neuropsychiatric lupus erythematosus' by Papadaki et al 2 and for giving us the opportunity to clarify aspects of our work. (bmj.com)

Dynamic Susceptibility Contrast-Enhanced MR Perfusion. (ajnr.org)

Computed tomography (CT) including a CT perfusion (CTP) scan revealed bilateral thalamic hyperperfusion. (hindawi.com)
A subsequent CT perfusion scan (CTP) revealed hyperperfusion in the same areas (Figure 3 ) whereas CT angiography of the posterior circulation vessels did not show any abnormalities. (hindawi.com)

Regional cortical perfusion increases induced by a 6-month endurance training in young sedentary adults. (wellnessresources.com)
Overall, this study identified region-specific increases in local perfusion in a cohort of young adults that partly correlated with individual performance increases, hence, suggesting exercise dose dependency. (wellnessresources.com)

A donor heart undergoing ex vivo perfusion on the TransMedics Organ Care System. (nih.gov)
The TransMedics Organ Care System is the only platform for ex vivo heart perfusion that has been used for human transplantation. (nih.gov)
A donor heart undergoing perfusion on the TransMedics Organ Care System. (nih.gov)
Ex Vivo Porcine Organ Perfusion Models as a Suitable Platform for Translational Transplant Research. (nih.gov)
Comorbidities including myocardial infarction, hypothyroidism, and renal failure were correlated with variations in organ-specific perfusion. (snmjournals.org)

The video showcases a new technology called zoomed 7T perfusion functional MRI (fMRI). (nih.gov)

Compared to static cultures, perfusion-based engineered constructs were more rapidly vascularized and supported a superior survival of delivered cells upon in vivo ectopic implantation. (nature.com)

In the present study, pulse oximetry technology was used to evaluate changes in the perfusion index (PI) in both blocked and unblocked arms, and changes in the plethysmographic variability index (PVI) were evaluated once mechanical ventilation was instituted. (nih.gov)
In this current study, a new analysis technique was applied to ICG to objectively evaluate choroidal perfusion in subjects with non-neovascular AMD compared with subjects with normal eyes. (bmj.com)

Cerebral blood flow (CBF) or brain perfusion is considered a marker of local brain activity and has been associated with performance in language and domain-general functions. (easychair.org)
For this purpose, the human adipose stromal vascular fraction (SVF), composed of a heterogeneous mix of pericytes, endothelial/stromal progenitor cells, was cultured under direct perfusion flow on three-dimensional (3D) collagen scaffolds. (nature.com)
Cerebral perfusion pressure (CPP) is the net pressure gradient of blood flow in the brain and is maintained by a process known as autoregulation. (medscape.com)
nICP and noninvasive cerebral perfusion pressure (nCPP) on the left and right brain hemispheres were retrospectively calculated using a mathematical model associating TCD-derived cerebral blood flow velocity and ABP. (minervamedica.it)

When referring to this article, please cite it as X. Gjoka, R. Gantier, and M. Schofield, "Going from Fed-Batch to Perfusion,' BioPharm International 30 (7) 2017. (biopharminternational.com)

Respective adaptations in brain perfusion are discussed in the context of physical exercise-induced vascular plasticity. (wellnessresources.com)
Cerebral perfusion pressure was greater on the side of brain expansion, acting as the driving force to shift brain structures. (minervamedica.it)
Measuring brain activity using fMRI to track perfusion is not new. (nih.gov)

The meaning of the terms "overperfusion" and "underperfusion" is relative to the average level of perfusion that exists across all the tissues in an individual body. (wikipedia.org)
Tissues of interest across the body have a range of perfusion values. (snmjournals.org)

Fed-batch reactions typically last 10-14 days, while perfusion processes run for 30-60 days or longer. (biopharminternational.com)
While perfusion titers are typically less than those observed for fed-batch reactions, this feature is mitigated by the higher cell densities possible in perfusion reactions, which allows for the high productivities. (biopharminternational.com)
Both perfusion and fed-batch reactions provide, after clarification, harvest cell culture fluids that are suitable for downstream purification. (biopharminternational.com)

11 C]-butanol is a perfusion tracer with a superior extraction fraction compared with [ 15 O]-water and [ 13 N]-ammonia. (snmjournals.org)

This was likely mediated by pericytes, whose number was significantly higher (4.5-fold) under perfusion and whose targeted depletion resulted in lower efficiency of vascularization, with an increased host foreign body reaction. (nature.com)

Continuous cell culture, or perfusion, processes have been implemented to produce marketed biopharmaceuticals. (biopharminternational.com)
As with any continuous process, process development is generally accelerated and the need for scale-up and technology transfer is often avoided with perfusion processes. (biopharminternational.com)
However, there is growing interest in perfusion because these processes are continuous and often achieve much higher productivities. (biopharminternational.com)
Is the technology ready for perfusion processes? (manufacturingchemist.com)
In this white paper, we explore perfusion processes and how they are becoming a viable solution. (manufacturingchemist.com)

Krogh was the first to describe the adaptation of blood perfusion in muscle and other organs according to demands through the opening and closing of arterioles and capillaries. (wikipedia.org)
With the recent advent of improved tools to measure skeletal muscle perfusion and to examine the muscle microvasculature, it is anticipated that exploratory studies utilizing these new methodologies will help to identify the most promising experimental approaches to address fundamental issues regarding the skeletal muscle microvasculature and blood supply in old age. (nih.gov)

The SI unit is m3/(s·kg)[citation needed], although for human organs perfusion is typically reported in ml/min/g. (wikipedia.org)

Changes in perfusion were measured in the paired rest-CPT study. (snmjournals.org)
This pilot study demonstrates the ability to obtain reproducible measurements of total-body perfusion using [ 11 C]-butanol. (snmjournals.org)

XVIVO Perfusion AB is a medical technology company which develops solutions and systems for assessing and preserving organs outside the body and for selecting usable organs and maintaining them in optimal condition pending transplantation. (cision.com)
Estimated baseline perfusion values ranged from 0.02 to 1.95 mL·min −1 ·cm −3 across organs. (snmjournals.org)

A renal perfusion scintiscan is a nuclear medicine test. (medlineplus.gov)

T max perfusion maps were generated, and stroke severity and recovery were assessed up to day 90. (bmj.com)

Anatomy29

Organisms9

Diseases27

Chemicals and Drugs62

Analytical, Diagnostic and Therapeutic Techniques and Equipment88

Phenomena and Processes44

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture1

Information Science7

Health Care12

Tissue15

Cardiovascular perfusion6

Hepatic perfusion with melphalan3

Quantification1

Myocardial perfusion image1

SPECT9

Cardiac5

Arterial spin3

Higher perfusion2

Machine perfusion3

Temporal6

Assessment3

Demyelinating lesions1

Imaging14

Quantitative measurement1

Magnetic1

RCBF1

Liver transplantation1

Methods2

Clinical2

Fixation1

Patients5

Melanoma1

Bioreactor3

Occipital1

Oxygen4

Parameters1

Diffusion3

Ischemia1

Capillary1

Hypoperfusion5

Susceptibility1

Hyperperfusion2

Increases2

Organ5

Functional1

Vivo1

Evaluate2

Flow4

20171

Brain3

Tissues2

Reactions3

Extraction1

Significantly1

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Blood2

Typically1

Study2

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Stroke1