The biosynthesis and storage of catecholamines in chromaffin cell tumors may differ from the biosynthesis and storage in the normal medulla. (medscape.com)
Extra-adrenal chromaffin tissue tumors are referred to as paragangliomas or extra-adrenal pheochromocytomas. (hopkinsguides.com)
The tumors that arise from the largest sympathetic paraganglia forming the adrenal medulla are called pheochromocytomas (PHEOs). (encyclopedia.pub)
Tumors developing from paraganglia outside the adrenal gland are termed paragangliomas (PGLs). (encyclopedia.pub)
AIM: Paragangliomas are neural crest-derived neuroendocrine tumors, originating from paraganglia, which are dispersed neuroendocrine organs characterized by catecholamine and peptide-producing cells. (unime.it)
Neoplasms arising from these cells are pheochromocytomas (also called chromaffin or sympathetic paragangliomas, in contrast to non-chromaffin or parasympathetic paragangliomas of glomus cells). (wikipedia.org)
Paragangliomas can derive from either parasympathetic or sympathetic paraganglia. (bvsalud.org)
Extra-adrenal chromaffin1
In lower concentrations, extra-adrenal chromaffin cells also reside in the bladder wall, prostate, and behind the liver. (wikipedia.org)
Vagus nerve3
Chromaffin cells also settle near the vagus nerve and carotid arteries. (wikipedia.org)
the chromaffin cells settle near the sympathetic ganglia, the vagus nerve, paraganglia, and carotid arteries. (medscape.com)
Parasympathetic paraganglia include supracardiac paraganglia, paraganglia of the carotid body, middle ear, and larynx, as well as paraganglia distributed along the vagus nerve and several other smaller paraganglia [ 2 ] . (encyclopedia.pub)
Paraganglia represent groups of paraneurons derived from neural crest cells during embryonic development and are divided into sympathetic and parasympathetic. (encyclopedia.pub)
Sympathetic paraganglia consist of chromaffin cells and are involved in the secretion of catecholamines (norepinephrine, epinephrine, and dopamine), while parasympathetic paraganglia consist of glomus (nonchromaffin) cells and act as chemoreceptors [ 1 ] . (encyclopedia.pub)
Catecholamines3
The chromaffin cells release catecholamines: ~80% of adrenaline (epinephrine) and ~20% of noradrenaline (norepinephrine) into systemic circulation for systemic effects on multiple organs (similarly to secretory neurones of the hypothalamus), and can also send paracrine signals. (wikipedia.org)
This chronic increase of epinephrine and norepinephrine secretion causes desensitization of the chromaffin cells to catecholamines resulting in a decrease in production and presence of α2 adrenergic receptors on their cell membrane. (wikipedia.org)
Ganglia of the sympathetic2
There are (i.) a series of isolated masses, the paraganglia, associated singly or in groups with the ganglia of the sympathetic nervous system, (ii. (co.ma)
The paraganglia are rounded masses of chromaphil tissue, 1-3 mm. in diameter, placed inside, half inside, or immediately outside the capsules of the ganglia of the sympathetic system. (co.ma)
Cells14
Chromaffin cells, also called pheochromocytes (or phaeochromocytes), are neuroendocrine cells found mostly in the medulla of the adrenal glands in mammals. (wikipedia.org)
In order to activate chromaffin cells, the splanchnic nerve of the sympathetic nervous system releases acetylcholine, which then binds to nicotinic acetylcholine receptors on the adrenal medulla. (wikipedia.org)
2) Chromaffin cells (or pheochromocytes): These cells will migrate to the area adjacent to the sympathetic ganglia (hence the name paraganglia) and to the adrenal medulla where they will be the most abundant type of cells. (wikipedia.org)
In non-mammals, chromaffin cells are found in a variety of places, generally not organised as an individual organ, and may be without innervation, relying only on endocrine or paracrine signals for secretion. (wikipedia.org)
Chromaffin cells of the adrenal medulla are innervated by the splanchnic nerve and secrete adrenaline (epinephrine), noradrenaline (norepinephrine), some dopamine, enkephalin and enkephalin-containing peptides, and a few other hormones into the blood stream. (wikipedia.org)
Small bodies containing chromaffin cells occurring outside of the adrenal medulla, most commonly near the sympathetic ganglia and in organs such as the kidney, liver, heart and gonads. (nih.gov)
Chromaffin Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (jefferson.edu)
This graph shows the total number of publications written about "Chromaffin Cells" by people in this website by year, and whether "Chromaffin Cells" was a major or minor topic of these publications. (jefferson.edu)
Below are the most recent publications written about "Chromaffin Cells" by people in Profiles. (jefferson.edu)
chromaffin cells of the medulla, adrenal, enterochromaffin-like, paraganglia and beta cells of the pancreas. (elisakits.co.uk)
The diversification of neural-crest-derived sympathoadrenal (SA) progenitor cells into sympathetic neurons and neuroendocrine adrenal chromaffin cells was thought to be largely understood. (silverchair.com)
In-vitro studies with isolated SA progenitor cells had suggested that chromaffin cell differentiation depends crucially on glucocorticoids provided by adrenal cortical cells. (silverchair.com)
However, analysis of mice lacking the glucocorticoid receptor gene had revealed that adrenal chromaffin cells develop mostly normally in these mice. (silverchair.com)
Medulla1
Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system. (usda.gov)
Typically1
Typically one paraganglion, exceptionally a pair of paraganglia, is associated with each ganglion of the gangliated trunks and with each ganglion of the cœliac, renal, suprarenal, aortic, and hypogastric plexuses. (co.ma)
Tissue1
From seven to seventy masses of chromaphil tissue are developed in relation to the abdominal sympathetic plexuses, independently of the ganglia and in addition to the paraganglia. (co.ma)
Common1
These paraganglia are common throughout the body, but most are found in the head and neck area [ 3 ] . (encyclopedia.pub)
Adrenal medulla10
In order to activate chromaffin cells, the splanchnic nerve of the sympathetic nervous system releases acetylcholine, which then binds to nicotinic acetylcholine receptors on the adrenal medulla. (wikipedia.org)
2) Chromaffin cells (or pheochromocytes): These cells will migrate to the area adjacent to the sympathetic ganglia (hence the name paraganglia) and to the adrenal medulla where they will be the most abundant type of cells. (wikipedia.org)
Chromaffin cells of the adrenal medulla are innervated by the splanchnic nerve and secrete adrenaline (epinephrine), noradrenaline (norepinephrine), some dopamine, enkephalin and enkephalin-containing peptides, and a few other hormones into the blood stream. (wikipedia.org)
[ 1 ] Pheochromocytomas (PCCs) originate from the adrenal medulla, whereas paragangliomas (PGLs) arise from extra-adrenal paraganglia. (medscape.com)
Pheochromocytomas are neuroendocrine tumors of chromaffin cell origin which arise from the adrenal medulla and less commonly the extra-adrenal sympathetic paraganglia. (nih.gov)
Small bodies containing chromaffin cells occurring outside of the adrenal medulla, most commonly near the sympathetic ganglia and in organs such as the kidney, liver, heart and gonads. (nih.gov)
Termination of the adrenal medulla growth was found to be associated with decreased chromaffin cell proliferation, activation of canonical Wnt-signaling pathway, and enhanced expression of Sonic Hedgehog ligand. (bvsalud.org)
A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. (musc.edu)
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors originating from the chromaffin cells of the autonomic nervous system. (medscape.com)
Pheochromocytomas1
Neoplasms arising from these cells are pheochromocytomas (also called chromaffin or sympathetic paragangliomas, in contrast to non-chromaffin or parasympathetic paragangliomas of glomus cells). (wikipedia.org)
Neuroendocrine1
Chromaffin cells, also called pheochromocytes (or phaeochromocytes), are neuroendocrine cells found mostly in the medulla of the adrenal glands in mammals. (wikipedia.org)