• enzymology
  • In enzymology, a leucocyanidin oxygenase (EC 1.14.11.19) is an enzyme that catalyzes the chemical reaction leucocyanidin + 2-oxoglutarate + O2 ⇌ {\displaystyle \rightleftharpoons } cis- and trans-dihydroquercetins + succinate + CO2 + 2 H2O The 3 substrates of this enzyme are leucocyanidin, 2-oxoglutarate, and O2, whereas its 5 products are cis-dihydroquercetin, trans-dihydroquercetin, succinate, CO2, and H2O. (wikipedia.org)
  • In enzymology, a sulfur oxygenase/reductase (EC 1.13.11.55) is an enzyme that catalyzes the chemical reaction 4 sulfur + 4 H2O + O2 ⇌ {\displaystyle \rightleftharpoons } 2 hydrogen sulfide + 2 bisulfite + 2 H+ The 3 substrates of this enzyme are sulfur, H2O, and O2, whereas its 3 products are hydrogen sulfide, bisulfite, and H+. (wikipedia.org)
  • In enzymology, a senecionine N-oxygenase (EC 1.14.13.101) is an enzyme that catalyzes the chemical reaction senecionine + NADPH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons } senecionine N-oxide + NADP+ + H2O The 4 substrates of this enzyme are senecionine, NADPH, H+, and O2, whereas its 3 products are senecionine N-oxide, NADP+, and H2O. (wikipedia.org)
  • In enzymology, a pyrogallol 1,2-oxygenase (EC 1.13.11.35) is an enzyme that catalyzes the chemical reaction 1,2,3-trihydroxybenzene + O2 ⇌ {\displaystyle \rightleftharpoons } (Z)-5-oxohex-2-enedioate Thus, the two substrates of this enzyme are 1,2,3-trihydroxybenzene and O2, whereas its product is (Z)-5-oxohex-2-enedioate. (wikipedia.org)
  • Protein
  • Heme oxygenase-1 (HO-1) is a microsomal enzyme that degrades heme, a prosthetic group of the heme protein family (e.g., hemoglobin), into the bile pigment biliverdin. (clontech.com)
  • Zusätzlich bieten wir Ihnen Heme Oxygenase (Decycling) 1 Antikörper (375) und Heme Oxygenase (Decycling) 1 Proteine (36) und viele weitere Produktgruppen zu diesem Protein an. (antikoerper-online.de)
  • Carotenoid oxygenases are a family of enzymes involved in the cleavage of carotenoids to produce, for example, retinol, commonly known as vitamin A. This family includes a receptor which is abundantly expressed in retinal pigment epithelium, and binds plasma retinal binding protein. (wikipedia.org)
  • Myo-inositol oxygenase is a monomeric 33 kDa protein in both solution and crystal. (wikipedia.org)
  • Like other di-iron oxygenases, the iron coordination centers are buried deep inside the protein presumably to protect the cell from the superoxide and radical reaction intermediates that are formed. (wikipedia.org)
  • the MIOX protein fold diverges from that of other non-heme di-iron oxygenases including ribonucleotide reductase and soluble methane monooxygenase. (wikipedia.org)
  • This enzyme catalyses the following chemical reaction pentalenene + 2 NADPH + 2 H+ + 2 O2 ⇌ {\displaystyle \rightleftharpoons } pentalen-13-al + 2 NADP+ + 3 H2O (overall reaction) (1a) pentalenene + NADPH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons } pentalen-13-ol + NADP+ + H2O (1b) pentalen-13-ol + NADPH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons } pentalen-13-al + NADP+ + 2 H2O Pentalenene oxygenase is a heme-thiolate protein (P-450). (wikipedia.org)
  • This enzyme catalyses the following chemical reaction (-)-vetispiradiene + 2 NADPH + 2 H+ + 2 O2 ⇌ {\displaystyle \rightleftharpoons } solavetivone + 2 NADP+ + 3 H2O (overall reaction) (1a) (-)-vetispiradiene + NADPH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons } solavetivol + NADP+ + H2O (1b) solavetivol + NADPH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons } solavetivone + NADP+ + 2 H2O Premnaspirodiene oxygenase heme-thiolate protein (P-450). (wikipedia.org)
  • Heme oxygenase-1 modulates thrombomodulin and activated protein c levels to attenuate lung injury in cecal ligation and puncture-induced acute lung injury mice," Experimental Lung Research , vol. 38, no. 4, pp. 173-182, 2012. (hindawi.com)
  • gene
  • Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lung prevents bleomycin-induced pulmonary fibrosis via a Fas-Fas ligand-independent pathway," Human Gene Therapy , vol. 13, no. 16, pp. 1945-1960, 2002. (hindawi.com)
  • Beta-apo-4'-carotenal oxygenase (EC 1.2.1.82, beta-apo-4'-carotenal dehydrogenase, YLO-1, carD (gene)) is an enzyme with systematic name 4'-apo-beta,psi-carotenal:NAD+ oxidoreductase. (wikipedia.org)
  • degradation
  • This enzyme catalyses the following chemical reaction Pheophorbide A + NADPH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons } red chlorophyll catabolite + NADP+ Pheophorbide A oxygenase participates in chlorophyll degradation. (wikipedia.org)
  • rightleftharpoons
  • This enzyme catalyses the following chemical reaction 4,4'-diapolycopene + 4 AH2 + 4 O2 ⇌ {\displaystyle \rightleftharpoons } 4,4'-diapolycopenedial + 4 A + 6 H2O Diapolycopene oxygenase is involved in the biosynthesis of C30 carotenoids such as staphyloxanthin. (wikipedia.org)
  • This enzyme catalyses the following chemical reaction all-trans-8'-apo-beta-carotenal + O2 ⇌ {\displaystyle \rightleftharpoons } all-trans-retinal + (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial All-trans-8'-apo-beta-carotenal 15,15'-oxygenase contains an Fe2+-4His arrangement. (wikipedia.org)
  • carotenoids
  • Carotenoid oxygenases cleave a variety of carotenoids into a range of biologically important products, including apocarotenoids in plants that function as hormones, pigments, flavours, floral scents and defence compounds, and retinoids in animals that function as vitamins, visual pigments and signalling molecules. (wikipedia.org)
  • cardiac
  • Effects of heme oxygenase-1 upregulation on blood pressure and cardiac function in an animal model of hypertensive myocardial infarction," International Journal of Molecular Sciences , vol. 14, no. 2, pp. 2684-2706, 2013. (hindawi.com)
  • Heme oxygenase-1: an emerging therapeutic target to curb cardiac pathology. (biomedsearch.com)
  • activation
  • Hemin inhibits NLRP3 inflammasome activation in sepsis-induced acute lung injury, involving heme oxygenase-1," International Immunopharmacology , vol. 20, no. 1, pp. 24-32, 2014. (hindawi.com)
  • physiological
  • Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. (abcam.com)
  • therefore, heme oxygenase-1 monitoring may prove useful for the identification of physiological stress inducers. (clontech.com)
  • Under normal physiological conditions, the activity of heme oxygenase is highest in the spleen, where old erythrocytes are sequestrated and destroyed. (wikipedia.org)
  • family
  • This family includes tryptophan 2,3-dioxygenase (TDO, also sometimes referred to as tryptophan oxygenase and L-tryptophan pyrrolase) and the closely related indoleamine 2,3-dioxygenase enzyme (IDO). (wikipedia.org)
  • role
  • Ribulose-1, 5-bisphosphate carboxylase/oxygenase, Rubisco, plays an important role in photosynthesis as well as in photorespiration. (springer.com)
  • blood
  • This 96-well format in vitro enzyme immunoassay kit is intended for the quantitation of rat heme oxygenase-1 in blood, cell culture supernatant, and various organ systems. (clontech.com)
  • mouse
  • The Rat Heme Oxygenase-1 EIA Kit (Precoated) is a solid phase sandwich ELISA that utilizes two mouse monoclonal heme oxygenase-1 antibodies, one of which is coated on the plate and the other of which is peroxidase-labeled. (clontech.com)
  • groups
  • Oxygenases were discovered in 1955 simultaneously by two groups, Osamu Hayaishi from Japan and Howard S. Mason from the US. (wikipedia.org)