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  • occurs
  • The reversible phosphorylation-dephosphorylation reaction occurs in every physiological process, making proper function of protein phosphatases necessary for organism viability. (wikipedia.org)
  • Email
  • To receive news and publication updates for Oxidative Medicine and Cellular Longevity, enter your email address in the box below. (hindawi.com)
  • synthase
  • Nitroglycerin-induced endothelial dysfunction and tolerance involve adverse phosphorylation and S-glutathionylation of endothelial nitric oxide synthase: beneficial effects of therapy with the AT1 receptor blocker telmisartan," Arteriosclerosis, Thrombosis, and Vascular Biology , vol. 31, no. 10, pp. 2223-2231, 2011. (hindawi.com)
  • Cardiac Akt2 expression and phosphorylation was decreased and insulin-induced cardiac Akt2 and GSK-3β phosphorylation and glycogen synthase dephosphorylation were also decreased in WT, but not MT-TG, diabetic mice. (ahajournals.org)
  • sumoylation
  • The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. (wikipedia.org)
  • This include sites for N-acetyltransferase (NetAcet 1-), glycation of ε amino groups of lysines (NetGlycate 1.0), mucin type GalNAc O-glycosylation (NetOglyc 4.0), phosphorylation (NetPhos 2.0), sumoylation (SUMOplot Analysis Program) and O-ß-GlcNAc attachment(YinOYang WWW). (wikipedia.org)
  • NADPH
  • Thionicotinamide and other nicotinamide analogs are potential inhibitors of NADK, and studies show that treatment of colon cancer cells with thionicotinamide suppresses the cytosolic NADPH pool to increase oxidative stress and synergizes with chemotherapy. (wikipedia.org)
  • form
  • In addition, PFOSA is thought to be the biologically active form of the insecticide Sulfluramid (N-ethyl perfluorooctanesulfonamide) as it is an extremely potent uncoupler of oxidative phosphorylation with an IC50 of about 1 micromolar (≈500 nanograms per milliliter or parts per billion). (wikipedia.org)