Ovarian follicle. Medical search. Frequent questions

Each primordial follicle contains an immature egg that can potentially develop and ovulate in the future. (advancedfertility.com)
In this study we tested the expression of CDKIs p15, p16, p21 and p27 by immunohistochemistry to determine the role of CDKIs in the initiation of primordial follicle growth. (biomedcentral.com)
Further studies are needed to investigate the factors that regulate the expression of p16 in the oocyte, which might also govern the initiation of primordial follicle growth. (biomedcentral.com)
p15, p16, p21 and p27 in mouse ovaries by immunohistochemistry to assess whether the initiation of primordial follicle growth was associated with the expression of CDKIs. (biomedcentral.com)
The mechanism(s) underlying effects of the latter compound may involve alterations in apoptosis, survival factors such as KIT/Kit Ligand, and/or the cellular signaling that maintains primordial follicle dormancy. (hal.science)
Mammalian ovarian primordial follicle activation and regulation is considered as one of the most important stages of folliculogenesis and as such requires exquisite control. (edu.au)
This study demonstrates that the cytokine Leukemia Inhibitory Factor (LIF) activates the Janus Kinase 1/Signal Transducers and Activators of Transcription 3 (JAK1/STAT3) signaling pathway in pre-granulosa cells and positively regulates primordial follicle activation. (edu.au)
The foremost drawback of ovarian tissue cryopreservation and re-transplantation (OTCT) technique is the rapid loss of the primordial follicle (PF) pool. (dundee.ac.uk)

Schenken, RS & Hodgen, GD 1983, ' Follicle-stimulating hormone induced ovarian hyperstimulation in monkeys: Blockade of the luteinizing hormone surge ', Journal of Clinical Endocrinology and Metabolism , vol. 57, no. 1, pp. 50-55. (uthscsa.edu)
In animal studies, changes in the concentration of testosterone, luteinizing hormone and follicle-stimulating hormone in serum or in testicular samples have also been linked to exposure to radiofrequency radiation. (ewg.org)
Two groups were irradiated at the highest dose, one fed AIN-93M chow and the other fed AIN-93M chow supplemented with 150 mg/kg diet alpha lipoic acid (ALA). PARTICIPANTS/MATERIALS, SETTING, METHODS: We quantified the numbers of ovarian follicles, measured serum follicle stimulating hormone (FSH) and luteinizing hormone (LH) concentrations, and analyzed histone H2AX phosphorylation, oxidative damage and apoptosis markers in the ovarian follicles. (cdc.gov)

At the time of puberty, women have approximately 200,000 to 300,000 follicles, each with the potential to release an egg cell (ovum) at ovulation for fertilization. (wikipedia.org)
Cumulus oophorus is a cluster of cells (called cumulus cells) that surround the oocyte both in the ovarian follicle and after ovulation. (wikipedia.org)
For several primary oocytes that complete meiosis I each month, only one or a few functional oocyte, the dominant follicles, completes maturation and undergoes ovulation. (wikipedia.org)
Objective -To evaluate gonadotropin secretion and ovarian function after administration of deslorelin acetate to induce ovulation in mares. (avma.org)
Diameter of the largest follicle was significantly smaller during 2 days of the diestrous period after ovulation in deslorelin-treated mares than in control mares. (avma.org)
In mammals, oocytes mature within structures called follicles before they are released from the ovary during ovulation. (sdbcore.org)
The follicle at this stage is called a preovulatory or Graafian follicle (E). It is ready for ovulation and fertilization [1]. (sdbcore.org)
In the laying hen ovary, the cyclic recruitment of a follicle represents a process in which a single follicle is selected to enter the rapid growth phase and undergo final maturation prior to ovulation. (psu.edu)
In recent years, exciting progress has been made towards unravelling the complex intraovarian control mechanisms that, in concert with systemic signals, coordinate the recruitment, selection and growth of follicles from the primordial stage through to ovulation and corpus luteum formation. (reading.ac.uk)
While most people have a good grasp of what ovulation involves, fewer may understand exactly what ovarian follicles are and their role in the process of getting pregnant. (ivi.uk)
My menstrual period in recent years is not very accurate, I want a baby, I do not know how to accurately know when ovulation, I heard that you can use the follicle monitoring, don't know how? (pku-allieddisorders.org)
Link to all annotated objects annotated to ovulation from ovarian follicle. (planteome.org)
Link to all direct and indirect annotations to ovulation from ovarian follicle. (planteome.org)
The effects of HCG and prostaglandins on ovulation, cAMP and steroidogenesis in the rat pre-ovulatory ovarian follicle / by Betty Mukatimui Munalula. (who.int)
Remodeling of ovarian follicle extracellular matrix is essential for ovulation and vascularization of the corpus luteum (CL). (sahmri.org.au)
The protease activity of ADAMTS1 mediates neomorphogenesis of the ovulating follicle wall and COC matrix necessary for successful ovulation and fertilization, as well as subsequent catabolism of versican required for degradation of COC matrix after fertilization. (sahmri.org.au)

Advances in our understanding of intraovarian regulatory mechanisms should facilitate the development of new approaches for monitoring and manipulating ovarian function and improving fertility in domesticated livestock, endangered species and man. (reading.ac.uk)
Ovarian follicles play an essential role in a woman's fertility - both in getting pregnant and during the early stages of pregnancy. (ivi.uk)
Estrogenic endocrine disruptors may alter follicle formation/development and impair fertility or normal development of offspring. (hal.science)
This case report suggests that continuous follicle monitoring may increase the probability of having a child in a subset of patients with primary ovarian insufficiency and desired fertility, although the validity and efficacy of such management has not been established. (elsevierpure.com)
ADAMTS1 is an extracellular metalloprotease induced in ovarian follicles by ovulatory hormones and is required for fertility. (sahmri.org.au)
Lactating cows with ≤15 ovarian follicles have lower reproductive performance compared with cows with higher numbers of follicles, but the existence of a positive association between high numbers of ovarian follicles and fertility is yet to be established. (teagasc.ie)
An ART cycle starts when a woman begins taking fertility drugs or having her ovaries monitored for follicle production. (cdc.gov)
Ovarian hyperstimulation syndrome (OHSS) is a problem that is sometimes seen in women who take fertility medicines that stimulate egg production. (medlineplus.gov)
Aging is associated with a decline in the number of ovarian follicles, menstrual irregularities, ovarian hormonal deficiency, anovulation, decreased fertility, and, finally, a complete and irreversible cessation of menses known as menopause, usually occurring at a mean age of 51 years. (medscape.com)

The total number of ovarian follicles ≥3 mm in diameter (antral follicle count, AFC) during follicular waves varies among cattle of similar age, but AFC is highly repeatable within individuals. (teagasc.ie)

The primary oocyte turns into a secondary oocyte in mature ovarian follicles. (wikipedia.org)

An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries. (wikipedia.org)
Ovarian reserve" refers to the reserve of the ovaries (remaining egg supply) to be able to make babies. (advancedfertility.com)
Antral follicle counts are a good predictor of the number of mature follicles that we will be able to stimulate in the woman's ovaries when we give injectable FSH medications that are used for in vitro fertilization. (advancedfertility.com)
Unfortunately, we do not live in a perfect world, and some ovaries have not yet read up on antral follicle counts to know how they are supposed to respond to stimulation. (advancedfertility.com)
In this study, we surveyed mouse ovaries and found, for the first time, transient appearance of nuage-like structures in oocytes of primordial follicles. (ntu.edu.sg)
Cigarette smoking is linked to menopause occurring 1-4 yr earlier than with nonsmokers, and components of smoke, polycyclic aromatic hydrocarbons, can cause follicle depletion in rodents or in ovaries in vitro. (hal.science)
Morphological assessment of peri-ovulatory ovaries revealed abnormal morphogenesis with a lack of thecal/vascular invagination in the basal region of follicles. (sahmri.org.au)
Cleavage of the ADAMTS1 substrate, versican, at these invaginating regions was abundant in Adamts1 +/- but undetectable in Adamts1 -/- ovaries, indicating that processing of versican by ADAMTS1 is involved in ovulating follicle remodeling. (sahmri.org.au)
The study aimed to quantify the concentrations of free IGF-I in serum and fluid of ovarian follicles in pre-pubertal gilts and describe the ovarian morphology by measuring the size of the ovaries and counting the number of surface follicles. (ufla.br)
The description of ovarian morphometry was performed in 100 ovaries from randomly selected gilts. (ufla.br)
These activities can cause ovarian discomfort and may cause ovarian cysts to rupture or leak, or cause the ovaries to twist and cut off blood flow (ovarian torsion). (medlineplus.gov)
Ovarian ultrasonography can be useful in the workup of patients with primary ovarian insufficiency, as it will identify those women with multifollicular ovaries and suggest the diagnosis of either autoimmune oophoritis or 17-20 desmolase deficiency. (medscape.com)
Ovaries and ovarian portions of ovotestes appear normal and demonstrate follicular growth with estradiol production. (medscape.com)
Many of these women, especially early on in diagnosis, may be experiencing some intermittent ovarian function, so it may not be a complete failure of the ovaries," McKenzie said. (medscape.com)

After rupturing, the follicle is turned into a corpus luteum. (wikipedia.org)
Estradiol is produced primarily in the ovary (follicle, corpus luteum), but small quantities are also formed in the testes and in the adrenal cortex, as well as in fat cells. (cdc.gov)

In a larger perspective, the whole folliculogenesis from primordial to preovulatory follicle is located in the stage of meiosis I of ootidogenesis in oogenesis. (wikipedia.org)
This, in turn, contributed to the reduction of morphological disorders of folliculogenesis and created the conditions for accelerated recovery of the relative area of generative elements of the ovary (at the stages of primary, preovulatory and atretic follicles) as early as 7 days after hyperthermia. (nih.gov)
The purpose of the present study was to evaluate the in vivo effect of the GnRH analogue leuprolide acetate (LA) on follicular development and apoptosis-related mechanisms in preovulatory ovarian follicles (POF) obtained from prepubertal eCG-treated rats. (uba.ar)

Any ovarian follicle that is larger than about three centimeters is termed an ovarian cyst. (wikipedia.org)
An ovarian follicle is a small sac (cyst) on the ovary. (healthwise.net)

Follicle development and serum concentrations of gonadotropins were monitored daily during 1 estrous cycle. (avma.org)
Administration of pure FSH on days 1 through 12 of the menstrual cycle resulted in significant ovarian hyperstimulation, as manifested by the development of multiple (bilateral) ovarian follicles and sustained high serum estradiol levels (∼400 pg/ml). (uthscsa.edu)
Consistent with near-total depletion of ovarian follicles in the 50 cGy group, serum concentrations of FSH and LH were significantly elevated at 8 weeks. (cdc.gov)
Primary ovarian insufficiency (POI) (premature ovarian failure, premature menopause, or early menopause) is a condition characterized by amenorrhea, hypoestrogenism, and elevated serum gonadotropin levels in women younger than 40 years. (medscape.com)
Occult primary ovarian insufficiency presents as unexplained infertility in a patient with a normal basal serum follicle-stimulating hormone (FSH) level. (medscape.com)
Next on the continuum, biochemical primary ovarian insufficiency presents as unexplained infertility in patients with an elevated basal serum FSH level. (medscape.com)

The other follicles that begin to mature will regress and become atretic follicles, eventually deteriorating. (wikipedia.org)
Oocytes of atretic follicles showed stronger staining with all four CDKIs. (biomedcentral.com)
After 48 h of LA treatment, the numbers of atretic and preantral follicles were increased as compared with controls, whereas the number of antral follicles had decreased. (uba.ar)

Concentrations of follicle-stimulating hormone (FSH) were lower in deslorelin-treated mares on days 5 through 14 than in control mares. (avma.org)
The recent availability of recombinant follicle stimulating hormone (rFSH), with its high level of purity and batch-to-batch consistency has made it an attractive alternative to urinary FSH (uFSH) for ovarian stimulation. (mcmaster.ca)
In particular, the follicle stimulating hormone (FSH) , released by the pituitary gland, which causes the follicles to mature. (ivi.uk)
Diagnosis involves confirmation of 4-6 months of amenorrhea or oligomenorrhea and two measurements of elevated follicle-stimulating hormone (FSH). (medscape.com)

Following conventional ovarian stimulation with exogenous gonadotropins, follicles were measured during oocyte collection. (ovationfertility.com)
The availability of a pure human FSH preparation for studies of the primate ovarian/menstrual cycle permitted novel experiments on gonadotropic stimulation of follicular growth in monkeys. (uthscsa.edu)
ART cycles include any process in which (1) an ART procedure is performed, (2) a woman has undergone ovarian stimulation or monitoring with the intent of having an ART procedure, or (3) frozen embryos have been thawed with the intent of transferring them to a woman. (cdc.gov)
An ART cycle in which ovarian stimulation was performed but the cycle was stopped before eggs were retrieved or before embryos were transferred. (cdc.gov)
Ovarian insufficiency is considered primary if the ovary fails to function normally in response to appropriate gonadotropin stimulation provided by the hypothalamus and pituitary. (medscape.com)
Ovarian insufficiency is considered secondary if the hypothalamus and pituitary fail to provide appropriate gonadotropin stimulation. (medscape.com)

Antral follicles are small follicles (about 2-9 mm in diameter) that we can see - and measure and count - with ultrasound. (advancedfertility.com)
Follicles are assigned developmental stages based on oocyte diameter and on the morphology of the associated somatic granulosa cells. (sdbcore.org)
Once primordial follicles are activated (B) [3], the oocyte increases in diameter and the granulosa cell layer proliferates and changes from a squamous epithelial layer to a single layered cuboidal epithelium , generating a primary follicle [1]. (sdbcore.org)
The follicles situated on the surface of each ovary were classified as small (SFs, 2 to 5mm in diameter) or large (LFs 6 to 10mm in diameter) and the follicular fluid was obtained by follicle aspiration. (ufla.br)

Xenobiotic effects on ovarian preantral follicles. (hal.science)
Ionizing radiation reduces preantral follicle numbers in rodents and humans in a dose-dependent manner. (hal.science)
Chemotherapeutic agents, such as alkylating drugs and cisplatin, also cause loss of preantral ovarian follicles. (hal.science)
Thus, specific exposures are known or suspected of detrimentally impacting preantral ovarian follicles, leading to early ovarian failure. (hal.science)
LA treatment caused an increase in the percentage of apoptotic cells in preantral and antral follicles. (uba.ar)
Anti-Müllerian hormone (AMH) or Müllerian-inhibiting substance, a dimeric glycoprotein secreted by granulosa cells of the preantral and small antral ovarian follicles. (cdc.gov)

Dominant follicle selection in monovular species may depend on differential FSH sensitivity amongst a growing cohort of small antral follicles. (reading.ac.uk)

For in vitro culture of follicles, there are various techniques to optimize the growth of follicles, including the use of defined media, growth factors and three-dimensional extracellular matrix support. (wikipedia.org)

Presently, ovarian follicle volumes can be measured rapidly and automatically from three-dimensionally reconstructed ultrasound images. (wikipedia.org)
Antral follicle counts by ultrasound are one of the best ovarian reserve tests that we currently have available. (advancedfertility.com)
The number of antral follicles visible on ultrasound is indicative of the number of microscopic (and sound asleep) primordial follicles remaining in the ovary. (advancedfertility.com)
At this point, the follicle is at a size where it's visible on an ultrasound scan. (ivi.uk)
In this paper a segmentation technique has been developed and discussed to segment different follicles from ultrasound image. (easychair.org)

In an industrial setting, 2-bromopropane caused infertility in men and women, and it can induce ovarian follicle depletion in rats. (hal.science)
The number of follicles in female laboratory rats went down significantly after they were exposed to radiofrequency radiation. (ewg.org)
Prenatal exposure to radiofrequency radiation in laboratory rats was associated with follicle degeneration and structural changes of ovary cells that produce estrogen. (ewg.org)

The presence of estradiol in developing ovarian follicles usually inhibits spermatogonia development in adjacent or contralateral seminiferous tubules. (medscape.com)
Women who develop POI lose ovarian activity before age 40, characterized by menstrual disturbance with raised gonadotropins and low estradiol. (medscape.com)

in addition to its endocrine role to suppress FSH secretion, increased output of inhibin by the selected dominant follicle(s) may upregulate LH-induced androgen secretion that is required to sustain a high level of oestradiol secretion during the pre-ovulatory phase. (reading.ac.uk)
Our interpretation is that when supraphysiological FSH levels persist into the late follicular phase, thereby overriding selection of the single dominant follicle of the natural cycle, secretion of an ovarian factor(s) blocks estrogen-induced LH surges. (uthscsa.edu)

They also produce peptides involved in ovarian hormone synthesis regulation. (wikipedia.org)
Negative regulation of the JAK/STAT pathway is controlled by the suppressor of cytokine signaling 4 (SOCS4) protein, which target members of negative feedback loops, Cardiotrophin like Cytokine (CLC), Poly (rC) Binding Protein 1 (PCBP1), and Cytosolic Malate Dehydrogenase (MDH1) to suppress follicle growth and development. (edu.au)
Parborell, F. Effects of a gonadotropin-releasing hormone agonist on rat ovarian follicle apoptosis: Regulation by epidermal growth factor and the expression of Bcl-2-related genes. (uba.ar)

During each monthly menstrual cycle, women develop several follicles, measuring around 0.025 mm to begin with. (ivi.uk)
Predictable menstrual cyclicity is a hallmark of healthy ovarian function during the reproductive years. (medscape.com)

However, these eventually develop into primary, secondary and tertiary vesicular follicles. (wikipedia.org)
Tertiary vesicular follicles (also called "mature vesicular follicles" or "ripe vesicular follicles") are sometimes called Graafian follicles (after Regnier de Graaf). (wikipedia.org)

Studies on later stages of follicle development indicate positive roles for granulosa cell-derived activin, BMP-2, -5 and -6, theca cell-derived BMP-2, -4 and -7 and oocyte-derived BMP-6 in promoting granulosa cell proliferation, follicle survival and prevention of premature luteinization and/or atresia. (reading.ac.uk)
STUDY QUESTION: Do charged iron particles, components of space radiation , cause premature ovarian failure? (cdc.gov)
SUMMARY ANSWER: Exposure to charged iron particles causes ovarian DNA damage, oxidative damage and apoptosis, resulting in premature ovarian failure. (cdc.gov)
WIDER IMPLICATIONS OF THE FINDINGS: We show for the first time that charged high-LET ions are highly damaging to the ovary even at low doses, causing premature ovarian failure. (cdc.gov)
In addition to causing infertility, premature ovarian failure has adverse implications for the functions of heart, brain, bone and muscle later in life. (cdc.gov)
Overt primary ovarian insufficiency is the clinical condition that has previously been referred to as premature ovarian failure or premature menopause. (medscape.com)

Women are born with a finite number of ovarian follicles, each containing a primary oocyte, or egg. (ivi.uk)

Additionally, miR-199-3p overexpression in cultured granulosa cells (GCs) from goose pre-hierarchical follicles significantly suppressed cell viability and migration. (bvsalud.org)
As a result, numbers of healthy ovarian follicles were significantly and dose-dependently depleted at 1 and 8 weeks post-irradiation, with 57, 84 and 99% decreases in primordial follicles at 8 weeks at the 5, 30 and 50 cGy doses, respectively (P (cdc.gov)

By comparison, when the duration of the cell culture prior to FSH challenge is increased to 18 h, GCs collected from 1- to 2-mm, 3- to 5-mm, and 6- to 8-mm follicles respond to a 3 h FSH challenge by increasing STAR expression and progesterone production, with the greatest response from GCs collected from 6- to 8-mm follicles. (psu.edu)

To more definitively address the potential risk of BPA on human ovarian steroidogenesis, additional experimental studies using biologically active BPA doses likely to reflect those within the ovarian follicle will be necessary, as will additional prospective investigations in human populations with the use of standardized assay methodology. (desdaughter.com)
In conclusion, miR-199-3p may participate in granulosa cell migration, viability, and steroidogenesis in goose ovarian follicles before selection by modulating ITGB8 and other ECM-related genes . (bvsalud.org)

Antral follicle counts (along with female age) are by far the best tool that we currently have for estimating ovarian reserve, the expected response to ovarian stimulating drugs, and the chance for successful pregnancy with in vitro fertilization. (advancedfertility.com)
In this article, we'll discuss what ovarian follicles are, how they're measured, why they're crucial to assisted reproduction treatment, and how they factor into the chances of having a successful pregnancy. (ivi.uk)
Women with primary ovarian insufficiency rarely ovulate and even more rarely achieve a spontaneous pregnancy. (elsevierpure.com)

Nonetheless, recombinant anti-Mullerian hormone administration did not affect granulosa cell proliferation and death rates in the growing follicles. (dundee.ac.uk)

Most women with POI retain intermittent ovarian function for many years, and, unlike women who are menopausal, pregnancies may occur. (medscape.com)

Ovarian follicles are the basic units of female reproductive biology. (wikipedia.org)
Cryopreservation of ovarian tissue is of interest to women who want to preserve their reproductive function beyond the natural limit, or whose reproductive potential is threatened by cancer therapy, for example in hematologic malignancies or breast cancer. (wikipedia.org)
Women are born with a finite population of ovarian follicles, which are slowly depleted during their reproductive years until reproductive failure (menopause) occurs. (hal.science)
Selection of quiescent follicles to enter the growing pool determines the rate of supply of maturing follicles over the female reproductive lifespan. (edu.au)
Ovarian insufficiency is a failure of the ovary to function adequately in a woman younger than 40 years, in its role either as an endocrine organ or as a reproductive organ. (medscape.com)
Known previously as primary ovarian failure, the syndrome of primary ovarian insufficiency (POI) no longer refers to a failure in part because of the term's negative connotations but mostly because it's not precisely accurate, said McKenzie, a reproductive endocrinologist and associate professor of ob/gyn. (medscape.com)

Primary ovarian insufficiency is not your mother's early menopause, Laurie McKenzie, MD, told attendees at the 2021 annual meeting of the American College of Obstetricians and Gynecologists . (medscape.com)

They also consist of granulosa cells and theca of follicle. (wikipedia.org)
Two such factors, bone morphogenetic proteins, RMP-4 and BMP-7, are expressed by ovarian stromal cells and/or theca cells and have recently been implicated as positive regulators of the primordial-to-primary follicle transition. (reading.ac.uk)
Concomitantly, activin, TGF-beta and several BMPs may exert paracrine actions on theca cells to attenuate LH-dependent androgen production in small to medium-size antral follicles. (reading.ac.uk)
At this stage, a layer of theca cells forms on the outside of the follicle, which contributes to the production of estrogen. (ivi.uk)
Expression of p15, p16, p21 and p27 did not vary in granulosa and theca cells by the follicle stage. (biomedcentral.com)

Similarly, during FSH-induced ovarian hyperstimulation, GnRH effects on LH secretion were blunted. (uthscsa.edu)

Cross sections of Carollia perspicillata (short-tailed fruit bat) ovary showing follicle development. (sdbcore.org)
Culture with Bone Morphogenetic Protein 6 (BMP6) enhances both CYP11A expression and FSH responsiveness at each stage of development, with the greatest response again occurring in GCs from 6- to 8-mm follicles. (psu.edu)
mice with null mutations in the gdf-9 gene or ewes with inactivating mutations in gdf-9 or bmp-15 genes are infertile with follicle development arrested at the primary stage. (reading.ac.uk)
Curiously, the ability of a mature oocyte to fertilize had no clear relationship with follicle size, although subsequent development to the blastocyst stage was strongly related to follicle size. (ovationfertility.com)
A patient with primary ovarian insufficiency who had only 13 follicle development cycles during 13 years, but had 2 live births resulting from intrauterine inseminations is reported. (elsevierpure.com)
During 10 of the 13 years that she was not pregnant and not breastfeeding, she underwent cyclic estrogen and progestin therapy with biweekly monitoring of follicle development. (elsevierpure.com)
Ovarian histology revealed an inhibitory effect of LA treatment on the follicular development induced by eCG. (uba.ar)
Patients with ovotesticular disorder of sexual development are individuals who have both ovarian and testicular tissue. (medscape.com)

Logistic regression was used to assess oocyte maturity, fertilization potential, and good blastocyst formation as a function of follicle size. (ovationfertility.com)
Logistic regression of successful fertilization (2pn) among mature oocytes did not find a significant relationship with follicle size (P=0.1792). (ovationfertility.com)
Each month, highly coordinated hormonal and ovarian morphological changes develop and release a mature oocyte that is ready for fertilization. (medscape.com)

MAIN RESULTS AND THE ROLE OF CHANCE: H2AX phosphorylation, lipid peroxidation, protein nitration and apoptosis were highly induced in ovarian follicles at 6 h and remained increased 1 week after irradiation. (cdc.gov)

Rupture of the follicle can result in abdominal pain (mittelschmerz) and is to be considered in the differential diagnosis in women of childbearing age. (wikipedia.org)
The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. (planteome.org)

In this study, we identified ADAMTS1-mediated structural and morphological changes in remodeling of the follicle and cumulus oocyte complex (COC). (sahmri.org.au)

The process by which the GC layer from the single 6- to 8-mm follicle selected each ovulatory cycle ultimately escapes inhibitory signaling to initiate FSH-responsiveness remains to be established. (psu.edu)

Prior to selection, the GC layer remains minimally responsive to a 3 h challenge with FSH (10 ng/mL), in vitro, compared to that from the most recently selected 9- to 12-mm follicle. (psu.edu)
Therefore, our study demonstrated unique data regarding the physiological concentration of free IGF-I in ovarian follicles, that can be used in future research to evaluate the addition of this hormone in the in vitro production media of porcine embryos with the goal to improve the technique efficiency. (ufla.br)

Treatment of follicles with epidermal growth factor (EGF) suppressed the spontaneous onset of DNA fragmentation, and a similar effect was observed in LA follicles. (uba.ar)

Here, we investigated whether anti-Mullerian hormone administration in the bilateral oophorectomy and transplantation group and internal AMH in the unilateral oophorectomy and transplantation group protect follicle reserve by regulating the expression of the molecules that control follicle growth after OTCT in mice. (dundee.ac.uk)

A plethora of growth factors, many belonging to the transforming growth factor-beta (TGF-beta) superfamily, are expressed by ovarian somatic cells and oocytes in a developmental, stage-related manner and function as intraovarian regulators of folliculogenesis. (reading.ac.uk)

She was diagnosed with primary ovarian insufficiency at 19 years of age and started infertility treatment at 23 years of age. (elsevierpure.com)

Tiny pockets of nutrient-rich follicular fluid form inside the follicle, which will later form the follicle's fluid-filled cavity (the antrum). (ivi.uk)

Follicles with this structure are called secondary follicles (C) [1]. (sdbcore.org)
At this stage, the secondary follicle develops an antrum, forming the basic structure of a mature follicle. (ivi.uk)
As defined by the World Health Organization, ovarian insufficiency can be caused by a primary disorder in the ovary or it can occur as a result of secondary causes. (medscape.com)

Anatomy23

Organisms13

Diseases10

Chemicals and Drugs58

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Phenomena and Processes41

Disciplines and Occupations1

Information Science1

Primordial follicle8

Luteinizing hormone3

Ovulation16

Fertility9

Antral follicle count1

Mature ovarian follicles1

Ovaries14

Corpus luteum2

Preovulatory3

Cyst2

Serum6

Atretic3

Stimulating Hormone4

Stimulation6

Diameter4

Preantral6

Small antral1

Growth of follicles1

Ultrasound5

Rats3

Estradiol2

Dominant follicle2

Regulation3

Menstrual2

Tertiary2

Premature6

Primary oocyte1

Significantly2

Progesterone1

Steroidogenesis2

Pregnancy3

Granulosa cell proliferation1

Intermittent ovarian function1

Reproductive6

20211

Theca5

Secretion1

Development8

Fertilization3

Apoptosis1

Rupture2

Morphological changes1

Ovulatory1

Vitro2

Spontaneous1

Mice1

Folliculogenesis1

Infertility1

Follicular fluid1

Secondary3