• Hypertrophic pulmonary osteoarthropathy (HPOA) (Pierre Marie-Bamberger syndrome): two cases presenting as acute inflammatory arthritis. (wikipedia.org)
  • Hypertrophic pulmonary osteoarthropathy is a rare syndrome characterized by a triad that includes periostitis, digital clubbing, and painful arthropathy of the large joints, especially large joints in the lower limbs with lung cancer. (biomedcentral.com)
  • Herein we describe a case of a giant cell carcinoma of the lung with hypertrophic pulmonary osteoarthropathy as a paraneoplastic syndrome. (biomedcentral.com)
  • The clinical stage was c-T2bN0M0 with paraneoplastic syndrome as a hypertrophic pulmonary osteoarthropathy. (biomedcentral.com)
  • Hypertrophic pulmonary osteoarthritis may occur as a secondary manifestation of lung malignancies. (biomedcentral.com)
  • Hypertrophic pulmonary osteoarthropathy (HPOA) is a paraneoplastic syndrome that occurs in patients with lung cancer. (biomedcentral.com)
  • [ 1 ] However, the highly rugose nature of his facial and scalp skin, and the presence of finger clubbing suggested the alternative diagnosis of pachydermoperiostosis, also known as hypertrophic pulmonary osteoarthropathy (primary hypertrophic osteoarthropathy autosomal recessive 2, PHOAR2). (medscape.com)
  • [ 12 ] Rare cases of primary pulmonary or pleural DSRCT have subsequently been identified. (medscape.com)
  • Pachydermoperiostosis (PDP), also known as Touraine-Solente-Golé syndrome and primary hypertrophic osteoarthropathy, is a very rare genodermatosis marked by facial skin thickening, furrowing and oiliness (pachydermia), digital clubbing, and periostosis. (logicalimages.com)
  • Secondary hypertrophic osteoarthropathy (SHO), also called secondary pachydermoperiostosis or Pierre-Marie Bamberger syndrome, is the main differential diagnosis. (logicalimages.com)
  • Periarticular hind foot swelling can be confused with ankle arthritis, exemplified by Lofgren's syndrome and hypertrophic osteoarthropathy where swelling is due to subcutaneous oedema and osteitis respectively, and the ankle joint is rarely involved. (nih.gov)
  • B cells, related to, and often associated with, primary nodal plasmacytoma and osteosclerotic myeloma (socalled POEMS, Takatsuki s or crow-fukase s syndrome). (geometry.net)
  • It is also part of the syndrome of primary or secondary hypertrophic osteoarthropathy (HOA). (biomedcentral.com)
  • The condition may occur alone (primary), or it may be secondary to diseases like lung cancer. (wikipedia.org)
  • citation needed] Hypertrophic osteoarthropathy is one of many distant effect disorders due to cancer, with lung cancer being the most common cause but also occurring with ovarian or adrenal malignancies. (wikipedia.org)
  • Treatment of lung cancer or other causes of hypertrophic osteoarthropathy results in regression of symptoms for some patients. (wikipedia.org)
  • The current TNM staging system is used for non-small cell lung cancer (NSCLC) and more recently neuroendocrine tumors including small cell lung cancer (SCLC), and provides a framework for the assessment of prognosis and the assignment of therapy for patients with a new diagnosis of lung cancer using the histopathologic evaluation of the primary tumor (T), lymph nodes (N), and metastatic disease (M). (sts.org)
  • [ 5 ] An earlier report, in 1956, by Babolini and Blasi, described the same clinicopathological entity using the nomenclature, "The pleural form of primary cancer of the lung. (medscape.com)
  • Homozygous mutations in the 15-hydroxyprostaglandin dehydrogenase gene in patients with primary hypertrophic osteoarthropathy. (univ-paris5.fr)
  • Clubbing may be hereditary (ie, primary hypertrophic osteoarthropathy , which is discussed in the next section), but, more often, it is acquired and is associated with a number of infectious, inflammatory, neoplastic, and vascular disorders. (medscape.com)
  • Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. (wikipedia.org)
  • The associated arthropathy of the large limb joints tends to be more severe and painful than in the primary form. (logicalimages.com)
  • Symptoms and signs may result from the location of the primary local invasion or compression of adjacent thoracic structures, distant metastases, or paraneoplastic phenomena. (medpagetoday.com)
  • And scrotal enlargement, chapter general considerations primary epithelial neoplasms of the already damaged organs. (albionfoundation.org)
  • 摘要: The overall diagnostic capabilities and utility of frequency-doubling technology (FDT) in patients with primary glaucoma, which was diagnosed by standard automated perimetry (SAP) and/or optic disc appearance as the gold standard, were assessed. (engineering.org.cn)
  • This category will also be used in primary coding to classify bacterial infections of unspecified nature or site. (cdc.gov)
  • Chronic progressive degeneration of the stress-bearing portion of a joint, with bizarre hypertrophic changes at the periphery. (wakehealth.edu)
  • The most common category of nonmesotheliomatous cancer to involve the pleura is represented by extrapleural primary malignancies that secondarily involve the pleura via metastatic spread. (medscape.com)
  • Hypogonadism , a decrease in male sex hormones may manifest as impotence, infertility, loss of sexual drive, and testicular atrophy , and can result from primary gonadal injury or suppression of hypothalamic/pituitary function. (alchetron.com)
  • There are two types of PHO: pachydermoperiostosis and cranio-osteoarthropathy. (nih.gov)
  • HOA can be a primary entity, known as pachydermoperiostosis, or can be secondary to extraskeletal conditions, with different prognoses and management implications for each. (nih.gov)
  • Causes of idiopathic or primary clubbing include pachydermoperiostosis, familial clubbing, and hypertrophic osteoarthropathy. (medscape.com)
  • Pachydermoperiostosis (PDP) is a form of primary hypertrophic osteoarthropathy (see this term) a rare hereditary disorder and is characterized by digital clubbing pachydermia and subperiosteal new bone formation associated with pain polyarthritis cutis verticis gyrata seborrhea and hyperhidrosis. (globalgenes.org)
  • Clubbing may be hereditary (ie, primary hypertrophic osteoarthropathy , which is discussed in the next section), but, more often, it is acquired and is associated with a number of infectious, inflammatory, neoplastic, and vascular disorders. (medscape.com)
  • Digital clubbing is classified into primary (ie, idiopathic, hereditary) and secondary forms. (medscape.com)
  • Primary hypertrophic osteoarthropathy (PHO), a rare hereditary disorder with digital clubbing, subperiosteal new bone formation, and arthropathy, has been linked mutations in the 15-hydroxy-prostaglandin dehydrogenase (15-PGDH) encoding gene HPGD , which causes PHO. (medscape.com)
  • HOA can be primary (hereditary or idiopathic) or secondary. (medscape.com)
  • HOA is classified either as primary (hereditary or idiopathic) or secondary. (medscape.com)
  • A form of primary hypertrophic osteoarthropathy, a rare hereditary disorder with characteristics of digital clubbing, pachydermia and subperiosteal new bone formation associated with pain, polyarthritis, cutis verticis gyrata, seborrhea and hyperhidrosis. (cdc.gov)
  • 2. Pulmonary hypertrophic osteoarthropathy in a patient with nonsmall cell lung cancer: Diagnosis with FDG PET/CT. (nih.gov)
  • 13. [A case of pulmonary pleomorphic carcinoma accompanied by pulmonary hypertrophic osteoarthropathy]. (nih.gov)
  • 15. Pulmonary hypertrophic osteoarthropathy and its resolution. (nih.gov)
  • With the exclusion of infection, loosening, instability, and crystalline synovitis, we made the presumptive diagnosis of pulmonary hypertrophic osteoarthropathy of the distal parts of both femora. (jbjs.org)
  • An unusual cause of late pain and effusion after total knee arthroplasty: pulmonary hypertrophic osteoarthropathy. (jbjs.org)
  • To our knowledge, this is the first report of pulmonary hypertrophic osteoarthropathy occurring in a patient who had had a total knee arthroplasty. (jbjs.org)
  • Primary pulmonary hypertrophic osteoarthropathy presents in young adults with digital clubbing, periosteal reaction of the long bones, and hypertrophic skin changes. (jbjs.org)
  • A review of the literature identified four reports of pulmonary hypertrophic osteoarthropathy associated with small-cell carcinoma of the lung. (jbjs.org)
  • The symptoms of pulmonary hypertrophic osteoarthropathy can include debilitating joint pain, effusions, and clubbing of the fingers. (jbjs.org)
  • Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. (nih.gov)
  • Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. (wikipedia.org)
  • Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by clubbing of the digits, periostitis of the long (tubular) bones, and arthritis. (medscape.com)
  • The clinical triad of digital clubbing, arthralgias, and ossifying periostitis that characterizes hypertrophic osteoarthropathy (HOA) has been recognized since the late 1800s and was previously known as hypertrophic pulmonary osteoarthropathy (HPOA). (medscape.com)
  • It is challenging to identify incomplete primary HOA, which can be misdiagnosed as other hypertrophic periostitis diseases. (akjournals.com)
  • NSCLC is diagnosed because of symptoms related to the primary tumor or regional or distant metastases, as an incidental finding on chest radiograph, or rarely because of a paraneoplastic syndrome such as hypercalcemia or hypertrophic pulmonary osteoarthropathy. (elsevierpure.com)
  • Hypertrophic pulmonary osteoarthropathy (HPOA) (Pierre Marie-Bamberger syndrome): two cases presenting as acute inflammatory arthritis. (wikipedia.org)
  • Periosteal reaction Hypertrophic osteopathy Armstrong DJ, McCausland EM, Wright GD (February 2007). (wikipedia.org)
  • Hypertrophic osteoarthropathy (HOA) is a medical condition characterized by abnormal proliferation of skin and periosteal tissues involving the extremities and characterized by three clinical features: digital clubbing (also termed Hippocratic fingers), periostosis of tubular bones, and synovial effusions. (nih.gov)
  • Hypertrophic osteoarthropathy (HOA) is characterized by clubbed fingers and periosteal new bone formation. (ogu.edu.tr)
  • Two types of bone changes can be found in the distal phalanges, hypertrophic and osteolytic. (medscape.com)
  • 16. [Analgesic effect of Pamidronate on bone pain in patient with hypertrophic pulmonary osteoarthropathy]. (nih.gov)
  • Osteoarthropathy, Primary Hypertrophic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (sdsu.edu)
  • This disorder exists in both primary and secondary forms. (jbjs.org)
  • His primary clinical focus includes the management of Non-Hodgkin's and Hodgkin's lymphomas. (moffitt.org)
  • Dr. Saeed's primary research expertise focuses on early phase clinical trials using novel chemotherapy combinations. (moffitt.org)
  • In some cases, the diagnosis of HOA as primary can be challenged with the development of a disease that is known to be associated with secondary HOA. (medscape.com)
  • Primary hypertrophic osteoarthropathy (PHO) is a genetically and clinically heterogeneous inherited disorder characterized by digital clubbing and osteoarthropathy, with variable features of pachydermia, delayed closure of the fontanels, and congenital heart disease. (nih.gov)
  • Transcriptome profiles of stem-like cells from primary breast cancers allow identification of ITGA7 as a predictive marker of chemotherapy response. (insilicase.com)
  • Therapy for HOA consists of treatment of the primary cause and symptomatic treatment. (medscape.com)
  • Primary hypertrophic osteoarthropathy (HOA) is a rare condition with no identifiable cause, accounting for 3%-5% of all HOA cases. (akjournals.com)
  • 14. Postchemotherapeutic reversibility of hypertrophic osteoarthropathy in a patient with bronchogenic adenocarcinoma. (nih.gov)
  • Lilip( Sunnyvale, CA) Assignee(s): Paracor Surgical, Inc. Sunnyvale, CA) Patent Number: 6,595,912 heart left: September 14, 2001 cell: A primary output for encompassing congestive mechanism lysis improves produced. (siriuspixels.com)
  • We present a case of incomplete primary PHOA at Hanoi Medical University Hospital in Vietnam. (akjournals.com)
  • Our case report and literature review aim to improve specialists' understanding of incomplete primary HOA and reduce the frequency of missed diagnoses. (akjournals.com)
  • This graph shows the total number of publications written about "Osteoarthropathy, Primary Hypertrophic" by people in this website by year, and whether "Osteoarthropathy, Primary Hypertrophic" was a major or minor topic of these publications. (sdsu.edu)
  • Below are the most recent publications written about "Osteoarthropathy, Primary Hypertrophic" by people in Profiles. (sdsu.edu)
  • 10. Hypertrophic pulmonary osteoarthropathy in nasopharyngeal carcinoma: an early sign of pulmonary metastasis. (nih.gov)