• Here, we demonstrate that the chemotherapeutic compound oxaliplatin acts as a double-edged sword. (tue.nl)
  • Organoplatinum chemistry is the chemistry of organometallic compounds containing a carbon to platinum chemical bond, and the study of platinum as a catalyst in organic reactions. (wikipedia.org)
  • Nickel, Palladium and Platinum (Comprehensive Organometallic Chemistry II) R.J. Puddephatt (Editor) 2002 0080423167 Synthesis of Organometallic Compounds: A Practical Guide Sanshiro Komiya Ed. S. Komiya, M. Hurano 1997 Jwu-Ting Chen "Platinum: Organometallic Chemistry" in Encyclopedia of Inorganic Chemistry 2006, John Wiley & Sons, New York. (wikipedia.org)
  • Most organoplatinum(0) compounds contain alkene and alkyne ligands. (wikipedia.org)
  • Zerovalent organoplatinum complexes lacking phosphine ligands are often prepared via PtCl2(COD). (wikipedia.org)
  • The compound adopts a cubane-like structure with four triply bridging iodide ligands. (wikipedia.org)
  • These properties have allowed the development of a rich chemistry of group 3 and 4 d-block and f-block transition metal compounds with pentamethylcyclopentadienyl ancillary ligands. (caltech.edu)
  • Such properties have facilitated the development of a rich and diverse reaction chemistry for compounds of the group 4 transition metals with pentamethylcyclopentadienyl ancillary ligands. (caltech.edu)
  • Organoplatinum and organopalladium chemistry are similar, but organoplatinum compounds are more stable and therefore less useful as catalysts. (wikipedia.org)
  • In contrast to nickel chemistry, where compounds such as CpNi(L)X are common, cyclopentadienyl derivatives of Pt(II) are rare, consistent with the reluctance of Pt(II) to become pentacoordinate. (wikipedia.org)
  • A hypothetical catalytic cycle for the selective oxidation of alkanes to alcohols by dioxygen may be based on the activation of C-H bonds at Pt(II) centers, coupled with additional known organoplatinum chemistry. (caltech.edu)
  • 4] I. Ojima, S. Patai, Z. Rappoport, The Chemistry of Organic Silicon Compounds (1989), Ch. 25 (1995) 1479. (ac.ir)
  • 2022) Chemistry of Heterocyclic Compounds, 58 (11), pp. 567-581. (org.ua)
  • Many organoplatinum(II) complexes arise via ortho-metalation and related intramolecular C-H activation processes. (wikipedia.org)
  • Use of a swivel frit assembly in the synthesis of air sensitive compounds is described along procedures for the addition of gases, volatile and nonvolatile liquids and solutions to reaction mixtures. (caltech.edu)
  • The compound Me(PEt3)2PtOTf reacts reversibly with triflic acid between -60 and -80 °C, forming methane and (PEt3)2Pt(OTf)2 at -20 °C. Weak acids often suffice even water and alcohol and in C-H bond activation the proton source is an alkane. (wikipedia.org)
  • Platinum(I) compounds are uncommon but generally are diamagnetic because they have Pt-Pt bonds. (wikipedia.org)
  • A historically significant organoplatinum(II) compound is Zeise's salt, which is obtained from ethylene and potassium tetrachloroplatinate: The colourless diolefin complex dichloro(cycloocta-1,5-diene)platinum(II) is a more modern relative, and is more widely used. (wikipedia.org)
  • The first organoplatinum compound ever synthesised was trimethylplatinum iodide from platinum(IV) chloride and methylmagnesium iodide, reported by Pope and Peachey in 1907. (wikipedia.org)
  • Heterogeneous catalysts based on platinum play a major role in the petrochemical industry, and it is assumed that these useful reactions proceed via surface-bound organoplatinum intermediates. (wikipedia.org)
  • The crystals are made of an organic compound that includes platinum. (trnmag.com)
  • Organic compounds which contain platinum as an integral part of the molecule. (bvsalud.org)
  • Convenient synthetic entry points to these compounds are (η^5-C_5Me_5)_2NbCl_2 and (η^5-C_5Me_5)_2TaCl_2. (caltech.edu)
  • chemotherapeutic regimen for management of primary disease containing carboplatin, cisplatin, or another organoplatinum compound. (nih.gov)
  • Herein, we synthesized an organoplatinum compound, etoplatin-N2β, by replacing the methioninejuxtaposing group of the drug etoposide with a cis-dichlorodiammineplatinum(II) moiety. (ntnu.edu.tw)
  • However, none of these studies actually measured the stability of these compounds in tissue culture medium (or in any other reaction mixture resembling in vivo conditions). (nih.gov)