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  • Renal
  • even propose that mycophenolate should be considered as a first-line induction therapy for treatment of lupus nephritis in patients without renal dysfunction. (wikipedia.org)
  • Polyarteritis nodosa (PAN), also known as panarteritis nodosa, periarteritis nodosa, Kussmaul disease, or Kussmaul-Maier disease, is a systemic vasculitis of small- or medium-sized muscular arteries, typically involving renal and visceral vessels but sparing the pulmonary circulation. (wikipedia.org)
  • tumor
  • We applied optimized Flow-sensitive Alternating Inversion Recovery (FAIR) ASL to non-invasively quantify tumor perfusion in a mouse xenograft model, in which acute (24-hour) and chronic (43-day) treatment effects of the VEGF inhibitor (Avastin ) was investigated. (ismrm.org)
  • To evaluate the impact of escalated doses to tumor sub-volumes with high FLT and FDG uptake prior to and during radiation therapy using post-treatment FDG images as an early surrogate for sub-volume-specific local control. (clinicaltrials.gov)
  • The patient's response is then tracked as closely as possible, often using surrogate measures such as tumor load (v. true outcomes, such as 5 year survival rate), and the treatment finely adapted to the patient's response. (wikipedia.org)
  • systemic
  • An immunosuppressant that has decreased the incidence of acute rejection in solid transplant recipients, mycophenolate is increasingly utilized as a steroid sparing treatment in autoimmune diseases and similar immune-mediated disorders including Beh├žet's disease, pemphigus vulgaris, refractory incomplete systemic lupus erythematosus, immunoglobulin A nephropathy, small vessel vasculitides, and psoriasis. (wikipedia.org)
  • brachytherapy
  • The aim of this study is to analyze the results of exclusive interstitial brachytherapy (IBT) as a conservative approach in the treatment of penile cancer confined to the glans or the shaft with long-term follow-up in a single institution. (springer.com)
  • We present a single-institution experience based on 73 cases of invasive penis cancer treated with interstitial brachytherapy with curative intent as the primary treatment in our center from 11/1992 to 11/2013. (springer.com)
  • tumors
  • In planning radiation treatment for each child, the study team determined that 11 patients should receive proton therapy, and that two other patients, because of their specific anatomy and the location of their tumors, should receive intensity-modulated X-ray therapy (IMXT). (prweb.com)
  • Proton treatment is notably valuable for treating localized, isolated, solid tumors before they spread to other tissues and to the rest of the body. (wikipedia.org)
  • He created and performed numerous previously un-described surgeries on the brain including a new approach to the removal of acoustic tumors that spared vital nerves for facial muscle function which had been routinely sacrificed in older techniques. (wikipedia.org)
  • surgically
  • The premise of this approach was that it would prevent the spread of cancerous cells into the body or blood stream when the malignant organs were removed surgically because the cancers were already dead prior to their removal. (wikipedia.org)
  • patient's
  • Precision medicine often involves the application of panomic analysis and systems biology to analyze the cause of an individual patient's disease at the molecular level and then to utilize targeted treatments (possibly in combination) to address that individual patient's disease process. (wikipedia.org)
  • 1992
  • The world's first valve-sparing aortic root replacement was done by Dr. Tirone David at Toronto General Hospital in 1992. (wikipedia.org)
  • transplant recipients
  • This disease is seen more often in immunosuppressed solid organ transplant recipients, an association that has led to the hypothesis that long-term immune stimulation in the setting of immunosuppression is the causative agent. (wikipedia.org)
  • diagnosis
  • Temporary regression or fluctuation of symptoms, spontaneous or in response to conventional treatment or hormonal events should not be considered of any significance in diagnosis. (wikipedia.org)
  • Radio isotope scan using technetium (99mTc) exametazime-labeled leukocyte SPECT may be useful in assessing the extent of disease and response to treatment but has little value in diagnosis, as the scan does not help differentiating EG from other causes of inflammation. (wikipedia.org)
  • Diagnosis may be suspected when protein is found in the urine, organ enlargement is present, or problems are found with multiple peripheral nerves and it is unclear why. (wikipedia.org)
  • dose
  • Computerised treatment planning systems began to be used in the 1970s to improve the accuracy and speed of dose calculations. (wikipedia.org)
  • Once the treatment planner has made an initial plan, the treatment planning system calculates the required monitor units to deliver a prescribed dose to a specific area, and the distribution of dose in the body this will create. (wikipedia.org)
  • Some patients have also noticed a remission phase when a four-dose infusion of rituximab is used before the leflunomide treatment is begun. (wikipedia.org)
  • cancers
  • IBT provides good local control with organ preservation, excellent tolerance and low complication rates in early-stage penile cancers. (springer.com)
  • Patients who, at a young age, had radiation therapy to the bladder region as part of treatment of another cancer type (sarcoma, testicular cancer, gynecological cancers) have an increased risk of developing bladder cancer in the long run ( 1 ). (oncolex.org)
  • Superficial and orthovoltage X-rays have application for the treatment of cancers at or close to the skin surface. (wikipedia.org)
  • It was not until the opening of the James M. Slater Proton Treatment and Research Center at Loma Linda University Medical Center in 1990, however, that the full benefits of proton treatment could be offered to patients with a wide variety of cancers. (wikipedia.org)
  • patients
  • For many years, the age of the patient, the condition of axillar lymph nodes, the size of the tumour, histological traits (in particular histological grade of malignancy and invasion of lymphatic vessels), condition of hormonal receptors and HER2 represented principal factors used for the stratification of breast cancer patients for the purposes of evaluating the prognosis and determining the appropriate strategy of treatment. (readbyqxmd.com)
  • Although the variables are useful for the prognostic evaluation of individual groups of breast cancer patients, their role in determining the individual risk level of the patient and in the selection of supplementary treatment is quite restricted. (readbyqxmd.com)
  • Long-term results of RTOG 91-11: a comparison of three nonsurgical treatment strategies to preserve the larynx in patients with locally advanced larynx cancer. (springer.com)
  • Reliable selection of candidates for organ-sparing treatment is vital to prevent undertreatment of patients. (ismrm.org)
  • preserve
  • Nerve sparing can preserve orgasmic function in most men after robotic-assisted laparoscopic radical prostatectomy. (ox.ac.uk)
  • liver
  • In 2015, surgeons performed the world's first triple organ transplant (lung, liver and pancreas) in 19 year old Reid Wylie at Toronto General Hospital. (wikipedia.org)
  • kidney
  • The kidney and heart are the most common organs involved. (wikipedia.org)
  • Initial treatment is most commonly either partial or complete removal of the affected kidney(s). (wikipedia.org)
  • Where the cancer has not metastasised (spread to other organs) or burrowed deeper into the tissues of the kidney, the five-year survival rate is 65-90%, but this is lowered considerably when the cancer has spread. (wikipedia.org)
  • symptoms
  • Some cases with asymptomatic IgG4-RD also require treatment, as some organs tend to not cause symptoms until the late stages of disease. (wikipedia.org)
  • Treatment with antibiotics or progesterone have been observed to cause a temporary regression of symptoms in some cases. (wikipedia.org)
  • conventional treatment
  • Pediatric oncologists have an arsenal of weapons against neuroblastoma, but high-risk forms of this cancer present a particular challenge, often frustrating conventional treatment from the start or recurring in a resistant form. (prweb.com)
  • early
  • 0.05 vs. the control group), suggesting FAIR ASL perfusion could be used as an early biomarker for treatment response. (ismrm.org)
  • Introduction Early rectal cancer (ERC) assessment should include prediction of the potential excision plane to safely remove lesions with clear deep margins and feasibility of organ preservation. (bmj.com)
  • survival
  • As survival rates improve for children with neuroblastoma, we need to reduce treatment-related long-term toxicities," said study leader Christine Hill-Kayser, M.D., a radiation oncologist in The Children's Hospital of Philadelphia's (CHOP) Cancer Center. (prweb.com)
  • reliable
  • Cobalt treatment still has a useful role to play in certain applications (for example the Gamma Knife) and is still in widespread use worldwide, since the machinery is relatively reliable and simple to maintain compared to the modern linear accelerator. (wikipedia.org)
  • disease
  • It is a heterogenous disease that varies in aggressiveness, which plays a significant role for the choice of treatment and follow-up care. (oncolex.org)
  • It does not literally mean the creation of drugs or medical devices that are unique to a patient, but rather the ability to classify individuals into subpopulations that differ in their susceptibility to a particular disease, in the biology or prognosis of those diseases they may develop, or in their response to a specific treatment. (wikipedia.org)
  • Dr. Rand personally performed over 2,000 surgeries for the treatment of Parkinson's Disease in which he used cryosurgery and selectively froze portions of the thalamus. (wikipedia.org)
  • This disease shows a distinct sinusoidal pattern of infiltration which spares the splenic white pulp and hepatic portal triads. (wikipedia.org)
  • cases
  • Nowadays choosing the organ sparing treatment, but in selected cases total laryngectomy is a valid treatment option. (scielo.cl)
  • This type of planning is only sufficiently adept to handle relatively simple cases in which the tumour has a simple shape and is not near any critical organs. (wikipedia.org)
  • Treatment is recommended in all symptomatic cases of IgG4-RD and also in asymptomatic IgG4-RD involving certain anatomical sites. (wikipedia.org)
  • An international panel of experts have developed recommendations for the management of IgG4-RD. They concluded that in all cases of symptomatic, active IgG4-RD that treatment is required. (wikipedia.org)
  • lesions
  • However, where advanced fibrotic lesions have resulted in irreversible damage, the response to glucocorticoids and other current treatment options may be poor or even absent. (wikipedia.org)
  • side effects
  • Preventive or therapeutic interventions can then be concentrated on those who will benefit, sparing expense and side effects for those who will not. (wikipedia.org)
  • The use of a transvaginal mesh is associated with side effects including pain, infection, and organ perforation. (wikipedia.org)
  • skin
  • all crimes are punishable by death, followed by involuntary donation of the perpetrator's transplantable organs (including skin, scalp, and teeth). (wikipedia.org)
  • patient
  • Precision medicine (PM) is a medical model that proposes the customization of healthcare, with medical decisions, treatments, practices, or products being tailored to the individual patient. (wikipedia.org)
  • In explaining the distinction from a similar common term of personalized medicine, the National Research Council explains: Precision Medicine refers to the tailoring of medical treatment to the individual characteristics of each patient. (wikipedia.org)