• made
  • For example, Octoxynol-9 is made by reacting p-(1,1,3,3-tetraemethylbutyl)phenol with 5-18 units of ethylene oxide, resulting in an average value of 9. (cosmeticsinfo.org)
  • skin
  • In a human skin irritation study, formulations containing 2% Octoxynol-9 were classified as moderately irritating and minimally irritating, respectively, in a 24-hour single-insult, occlusive patch test. (cosmeticsinfo.org)