Devices business unit consists of marketed products, such as Reactive Skin Decontamination Lotion Kit (RSDL) and Trobigard (atropine sulfate, obidoxime chloride). (stash.com)
Troops who are likely to be attacked with chemical weapons often carry autoinjectors with atropine and obidoxime which can be quickly injected into the thigh. (the-medical-dictionary.com)
As part of the deal, Emergent will supply the State Department with the Trobigard atropine sulfate/obidoxime chloride auto-injector, a drug-device for emergency use in the event of nerve agent or organophosphate poisoning, and RSDL (Reactive Skin Decontamination Lotion Kit), which is intended to remove or neutralize chemical warfare agents and T-2 toxin from the skin. (biohealthcapital.com)
Pralidoxime chloride (2-PAM) is the only cholinesterase-reactivating xenobiotic currently available in the United States. (mhmedical.com)
Pralidoxime chloride is a quaternary pyridinium oxime with a molecular weight of 173 Da. (mhmedical.com)
Obidoxime (Toxogonin, LuH-6) is an oxime used outside the United States that contains two active sites per molecule and is considered by some to be more effective than pralidoxime. (mhmedical.com)
23 , 24 , 88 An in vitro study using human erythrocyte AChE supported the superiority of obidoxime to pralidoxime in reactivating AChE inhibited by the dimethyl phosphoryl (malaoxon, -mevinphos) and diethyl phosphoryl OP compounds (paraoxon). (mhmedical.com)
On a molar basis, obidoxime is approximately 10 to 20 times more effective in reactivating AChE than pralidoxime. (mhmedical.com)
Nerve1
It was also used as a linker in the synthesis of certain nerve agent antidotes (asoxime chloride, obidoxime). (wikipedia.org)
Human1
88 A potential disadvantage is the concern that the phosphorylobidoxime generated from the reactivation of AChE by obidoxime could reinhibit AChE if not metabolized by a plasma enzyme similar or identical to human paraoxonase 1 (PON1). (mhmedical.com)
Chemical1
The defense achievements, unveiled in Tehran on Monday, comprised the Pars Cam detector device, an explosives and drugs detector device, anti-shock and explosion-proof polymer covers, a new generation of NBC (nuclear, biological, chemical) suits, and a production line for Obidoxime Chloride, a medicine for countering chemical agents. (presstv.ir)
TOXOGONIN1
Electrocorticographic recordings were performed prior, during and after injection of 4.5 LD 50 paraoxon, followed by injections of atropine and toxogonin (obidoxime) to prevent death. (bgu.ac.il)