• Anesthesia
  • Gallamine Triethiodide is a nondepolarizing neuromuscular blocking drug (NDMRD) used as an adjunct to anesthesia to induce skeletal muscle relaxation. (pharmacycode.com)
  • Neuromuscular blocking agent is used as an adjuvant in general anesthesia, electroshock therapy, endotracheal intubation, during incubation and endoscopic procedures, brief surgeries and as adjuncts in the treatment of encephalitis, tetanus, and poliomyelitis which propels the demand of the neuromuscular blocking agents over the forecast period. (whatech.com)
  • Cisatracurium (formerly recognized as 51W89, and marketed as Nimbex) is a bisbenzyltetrahydroisoquinolinium that has effect as a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. (wikipedia.org)
  • Laudexium metilsulfate is a neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. (wikipedia.org)
  • Present clinical anesthetic practice still employs the central principle of balanced anesthesia though with some differences to accommodate subsequent technological advances and introductions of new and better gaseous anesthetic, hypnotic and neuromuscular blocking agents, and tracheal intubation, as well as monitoring techniques that were nonexistent in the day of Gray and Halton: pulse oximetry, capnography, peripheral nerve stimulation, noninvasive blood pressure monitoring, etc. (wikipedia.org)
  • Mivacurium chloride (formerly recognized as BW1090U81, BW B1090U or BW1090U) is a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. (wikipedia.org)
  • Reversal Agent
  • MALVERN, PA, July 2017 - Recro Pharma, Inc. (Nasdaq:REPH), a revenue generating specialty pharmaceutical company focused on therapeutics for hospital and other acute care settings, today announced the acquisition of exclusive global rights to two novel neuromuscular blocking agents (NMBs) and a proprietary chemical reversal agent from Cornell University. (recropharma.com)
  • postoperative
  • Among patients who receive these agents, nonreversal is associated with an increased risk of postoperative pneumonia. (asahq.org)
  • relaxants
  • or = 14 days, and, aside from the prescribed study medications, discontinued treatment with all analgesics, anti-inflammatory agents, and skeletal muscle relaxants during the study period. (curehunter.com)
  • Muscle relaxants and intraperitoneal antibiotics as etiologic agents. (webmd.com)
  • Mutual potentiation of the neuromuscular effects of antibiotics and relaxants. (webmd.com)
  • compounds
  • Mivacurium belongs to a class of compounds that is commonly and most erroneously referred to as "benzylisoquinolines" when, in fact, it is a bisbenzyltetrahydroisoquinolinium agent, often abbreviated to bbTHIQ. (wikipedia.org)
  • patients
  • Sedative and neuromuscular blocking drug use in critically ill patients with head injuries. (springer.com)
  • an order to 'continue same meds' upon transfer from a critical care unit has led to continued use (sometimes fatal) of neuromuscular blocking agents for restless, but extubated patients. (thefreedictionary.com)
  • No patient was examined prior to use of NMB for preexistent abnormalities, and it does not appear that any of the study patients required or were given reversal agents, despite the "findings" of residual NMB. (asahq.org)
  • A great deal of neuromuscular and pharmacokinetic reserve is evident in many healthy, muscular patients yet not evident in debilitated geriatric patients, who will need complete reversal. (asahq.org)
  • We look forward to working with Recro Pharma Inc. to commercialize a series of proprietary neuromuscular blocking agents that may benefit patients and the medical community," said Dr. Brian Kelly, the Director of Cornell's Center for Technology Licensing at Cornell University. (recropharma.com)
  • residual
  • Did the residual effects disappear after reversal agents, and when? (asahq.org)
  • How did age, core temperature, body mass index, NMB agent used, and patient satisfaction correlate to the findings of individual's residual NMB hours after a single dose? (asahq.org)
  • proprietary
  • The replacement of both the N-methyl groups with N-allyl moieties yielded N,N-diallyl-bis-nortoxiferine, now recognized as alcuronium (and at one time marketed as the proprietary agent called Alloferin). (wikipedia.org)
  • surgical
  • These novel agents may meaningfully reduce the patient's post-procedure time in the operating room or post-acute care unit and could provide valuable cost savings to hospitals and ambulatory surgical centers. (recropharma.com)
  • Nimbex
  • By the time of its approval for human use, in 1995, by the US Food and Drug Administration, Burroughs Wellcome Co. had merged with Glaxo Inc., and cisatracurium was approved to be marketed as Nimbex by GlaxoWellcome Inc. The trade name "Nimbex" was derived from inserting an "i" to the original proposal "Nmbex," which stood for excellent Neuromuscular blocker. (wikipedia.org)
  • e.g., cisatracurium (Nimbex) is one such agent that does not elicit histamine release even up to 5xED95 doses. (wikipedia.org)
  • citation needed
  • citation needed] Most commonly, the histamine release following administration of these agents is associated with observable cutaneous flushing (facial face and arms, commonly), hypotension and a consequent reflex tachycardia. (wikipedia.org)
  • medications
  • Less common causes include: physical factors, biological agents such as semen, latex, hormonal changes, food additives such as monosodium glutamate and food colors, and topical medications. (wikipedia.org)