• Because a great many organ systems and varieties of tissues are represented within the mediastinum, tumors that occur in this area can represent many different clinical entities and pathologic processes. (medscape.com)
  • While neoplasms of the middle mediastinum are most commonly of lymphatic origin, neurogenic tumors also occasionally occur in this area. (medscape.com)
  • Neurogenic tumors are, by far, the most common neoplasm of the posterior mediastinum. (medscape.com)
  • Tumors originating from lymphatic, vascular, or mesenchymal tissues can also be found in this compartment. (medscape.com)
  • Numerous biologic markers have been identified for many tumors and will play a vital role in better identifying individual neoplasms so that treatment can be optimized. (medscape.com)
  • Tumors arising from the placental tissue include two distinct histological types: the benign vascular tumor, chorangioma, and very rarely, choriocarcinoma. (biomedcentral.com)
  • All categories of soft tissue tumors have been reported to involve the upper aerodigestive tract. (basicmedicalkey.com)
  • These tumors have markedly different prognoses and require different treatments than those for soft tissue tumors. (basicmedicalkey.com)
  • Fibroblastic or myofibroblastic tumors make up the majority of soft tissue tumors of the aerodigestive tract and range from nonneoplastic or benign proliferations (fibromas) to high-grade malignancies (undifferentiated high-grade pleomorphic sarcomas). (basicmedicalkey.com)
  • By comparison, capillary hemangiomas are the most common vascular tumors of infancy and can be found on skin, mucous membranes, and internal viscera [1]. (jocr.co.in)
  • Nonepithelial malignant neoplasms sometimes arise in mucinous tumors, typically as mural nodules. (hindawi.com)
  • Malignant vascular tumors (MVTs), mainly composed of angiosarcoma (AS) and hemangioendothelioma (HE), are considered one of the rarest soft tissue neoplasms in contrast to their benign counterparts. (turkjpath.org)
  • Papillary intralymphatic angioendothelioma (Dabska tumor) is a rarely metastasizing lymphatic vascular neoplasm that usually affects children and young adults. (anaisdedermatologia.org.br)
  • An incisional biopsy was performed, whose anatomopathological study evidenced an intralymphatic lesion, with prominent papillary formations and vascular axes lined by rounded and hyperchromatic cells, projecting into the lumen (hobnail cells), compatible with papillary intralymphatic angioendothelioma - Dabska tumor ( Figs. 3 and 4 ). (anaisdedermatologia.org.br)
  • A tumor of medium-to-large veins, composed of plump-to-spindled endothelial cells that bulge into vascular spaces in a tombstone-like fashion. (uchicago.edu)
  • Adenoma of the breast is a benign tumor, which is formed of fibrous and glandular breast tissue. (vsebolezni.com)
  • Chromosomes of the neoplasm were studied by the fluorescence in situ hybridization technique and the tumor was found to carry XX chromosomes. (biomedcentral.com)
  • whether the tumor is a primary placental or uterine neoplasm. (biomedcentral.com)
  • Wilms tumor is believed to arise from embryonic tissues called nephrogenic rests that fail to undergo normal involution ( 7 ). (abdominalkey.com)
  • The tumor is usually circumscribed by a pseudocapsule formed of compressed renal and perirenal tissues. (abdominalkey.com)
  • The purpose of this report is to describe the features of angiosarcoma arising in mucinous tumor that was misinterpreted as a benign vascular proliferation during the intraoperative consultation. (hindawi.com)
  • The frozen section diagnosis was at least mucinous borderline tumor, pending adequate tissue sampling for permanent sections to rule out mucinous adenocarcinoma. (hindawi.com)
  • Hemangioma, a benign tumor of the vascular endothelial cells with small endothelial spaces, occurring in the face. (beds.ac.uk)
  • Histologically, the tumor cells had granular or clear amphophilic cytoplasm with an oval nucleus and nests of cells delimited by connective tissue and vascular septations. (biomedcentral.com)
  • Although Kaposi's sarcoma is also classified as a malignant vascular neoplasm, there are contradictory data about the vascular origin and differentiation of this tumor. (turkjpath.org)
  • The most pronounced radiation effect of increased pO(2) occurred with tumor tissue with 50% of the maximum vessel density used in the simulations. (lu.se)
  • Has provided tumor tissue from a fresh core or excisional biopsy from soft tissue not previously irradiated. (who.int)
  • Capillary hemangiomas and pyogenic granulomas are benign vascular neoplasms that are usually identified clinically by their characteristic features. (jocr.co.in)
  • Capillary hemangiomas and pyogenic granulomas are well-known benign vascular neoplasms. (jocr.co.in)
  • Hemangioma is clinical term for designate a benign vascular neoplasm or vascular malformation of endothelial origin. (bvsalud.org)
  • Neoplasms and other masses originating from vascular or mesenchymal tissues also may be found. (medscape.com)
  • SFTs of the pleura are localized mesenchymal neoplasms composed of fibroblastlike cells believed to arise from the subpleural connective tissue. (medscape.com)
  • Kidney sarcoma is a rare malignant neoplasm that develops from one or more progenitor cell lines of the mesenchymal kidney tissue (muscle, fat, vascular elements). (medic-journal.com)
  • This is followed by coverage of neoplasms in the more traditional categories of epithelial, mesenchymal, and other categories. (abdominalkey.com)
  • Endoscopic ultrasonography-guided fine-needle aspiration revealed CD34-positive spindle-shaped cells in the fibrous tissue, suggestive of a mesenchymal neoplasm. (biomedcentral.com)
  • Both patients showed an arteriovenous 'steal' syndrome with distal ischemia, and it is possible that a local increase of vascular endothelial growth factor, as is the case in hypoxia situations, induces the endothelial proliferation. (thedoctorsdoctor.com)
  • 2005). The vascular endothelial growth factor (VEGF) is a 46 kD dimeric glycoprotein secreted by neoplastic cells, macrophages, plasma cells and lymphocytes, which triggers endothelial cell proliferation by interacting with specific receptors in a paracrine or autocrine fashion (Ferrara 2004). (vin.com)
  • The aim of this study was to raise and characterize a monoclonal antibody reactive with VEGF (vascular endothelial growth factor) in routinely fixed specimens and to use it to investigate its tissue distribution in normal and pathological specimens. (ox.ac.uk)
  • For example, modalities such as positron emission tomoggraphy (PET) and radionuclide studies may be able to assist in the diagnosis of specific neoplasms and in posttherapy surveillance for recurrent disease. (medscape.com)
  • This neoplasm should be considered in the differential diagnosis of vascular dermatoses, allowing early diagnosis and treatment. (anaisdedermatologia.org.br)
  • With this in mind, health-care providers should maintain a low clinical threshold to send soft tissue masses for histopathology to obtain an accurate diagnosis and to provide the best care possible. (jocr.co.in)
  • For this reason, a surgical procedure to remove all or a large portion of the thyroid gland may be necessary to obtain sufficient tissue for a definitive diagnosis of follicular thyroid cancer. (medscape.com)
  • The distinction between Hürthle cell adenoma and carcinoma is based on presence of capsular or vascular invasion, or both. (cap.org)
  • Pathological examination showing capsular or vascular invasion may be required for this determination. (medscape.com)
  • Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
  • A failure to intraoperatively recognize this malignant neoplasm may result in incomplete surgical staging procedure or inappropriate clinical management. (hindawi.com)
  • By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
  • In the remaining cases, angiosarcoma was associated with ovarian teratoma or epithelial neoplasm [ 2 , 4 ]. (hindawi.com)
  • More rarely, the masses found are associated with aberrant parathyroid or thyroid tissue. (medscape.com)
  • Follicular adenoma of the thyroid gland is one of the types of neoplasms of the thyroid gland of benign nature. (vsebolezni.com)
  • The most recognized subtype is the fibrous variant of Hashimoto thyroiditis, which is characterized by marked fibrous replacement of the thyroid parenchyma and microscopic changes typical of Hashimoto thyroiditis in the remaining tissue. (cap.org)
  • Hürthle cell neoplasms of the thyroid show a distinct nodule or nodules that are comprised mostly of large oncocytes with distinct cell borders, deeply eosinophilic and granular cytoplasm, and a large nucleus with prominent nucleolus. (cap.org)
  • Thyroid neoplasms arising from follicular cells (adenoma, carcinoma, and follicular/papillary carcinoma) show a broad range of overlapping clinical and cytologic features. (medscape.com)
  • X-ray relies on differentiation of adjacent structures using four basic tissue densities: air, fat, water (which includes soft tissues, both solid organs such as muscle and fluids such as blood), and bone (sometimes called metal density ). (radiologykey.com)
  • Recently, some studies have proposed new markers such as FLI1 6 and FKBP12 7 for vascular differentiation. (turkjpath.org)
  • Reactive angioendotheliomatosis (RAE) is a rare benign cutaneous vascular proliferation characterized by intravascular hyperplasia of endothelial cells and tuft-like proliferation of vessels. (thedoctorsdoctor.com)
  • A rare benign smooth muscle neoplasm involving the placental parenchyma is presented. (biomedcentral.com)
  • Cutaneous biopsy revealed RAE characterized by the proliferation of epithelioid and spindle-shaped cells in superficial and middermis lining vascular channels, arranged in clusters, and sometimes displaying an intravascular growth pattern. (thedoctorsdoctor.com)
  • These neoplasms can show follicular, trabecular, solid, or papillary growth patterns with occasional nuclear grooves or nuclear pseudoinclusions. (cap.org)
  • Current National Comprehensive Cancer Network (NCCN) guidelines recommend lobectomy plus isthmusectomy as the initial surgery for patients with follicular neoplasms, with prompt completion of thyroidectomy if invasive FTC is found on the final histologic section. (medscape.com)
  • The majority of these cases occur in soft tissues of extremities, and to date less than 40 cases have been described. (anaisdedermatologia.org.br)
  • Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases. (uchicago.edu)
  • Synovial sarcoma is a malignant soft-tissue neoplasm that most commonly affects the extremities near to, but not in continuity with, large joints. (medscape.com)
  • Weiss and Enzinger first reported epithelioid hemangioendothelioma (EHE) in 1982 as a rare vascular endothelial neoplasm arising in soft tissues [ 1 ]. (springeropen.com)
  • The cut surface is typically solid, soft, and gray or pink, with a texture and appearance resembling brain tissue. (abdominalkey.com)
  • It is a soft vascular tissue present in the interior of long bones. (powershow.com)
  • Now fully revised to include recent advances in the field, the second edition of Bone and Soft Tissue Pathology, a volume in the Foundations in Diagnostic Pathology series, is an essential foundation text for residents and pathologists. (elsevierhealth.com)
  • Some neoplasms appear more unique to the area, e.g., angiofibroma, while most can occur throughout the soft tissues of the entire body. (basicmedicalkey.com)
  • Clinicians should maintain a high clinical suspicion for both pyogenic granulomas and capillary hemangiomas in children and adults with a vascular soft tissue mass, even after trauma. (jocr.co.in)
  • Imaging of soft tissues of the neck can be essential in the evaluation of patients with a variety of chief complaints, including neck trauma, ingested or aspirated foreign body, nontraumatic neck pain and swelling, dysphagia and voice change, visible or palpable mass, and central nervous system complaints with possible vascular causes. (radiologykey.com)
  • In this chapter, we explore the modalities available for soft-tissue cervical imaging, discuss clinical indications for imaging in a variety of chief complaints, and review some characteristic findings of important pathology, using the figures throughout the chapter. (radiologykey.com)
  • Imaging of the soft tissues of the cervical spinal cord and ligaments are discussed in Chapter 3 . (radiologykey.com)
  • Who Needs Soft-Tissue Imaging? (radiologykey.com)
  • Given the range of potential pathology discussed earlier, it should come as little surprise that no single clinical decision rule can be used to inform decisions for soft-tissue neck imaging. (radiologykey.com)
  • Some soft-tissue neck abnormalities are best assessed with neither x-ray nor CT but rather with ultrasound, magnetic resonance imaging (MRI), fluoroscopy, or techniques such as bronchoscopy and esophagoscopy. (radiologykey.com)
  • Plain x-ray ( Figures 4-1 and 4-2 ) provides limited information about the soft tissues of the neck. (radiologykey.com)
  • For this reason, x-rays can demonstrate abnormal soft-tissue air ( Figures 4-3 to 4-5 ), deviation or compression of normal air-filled structures (the trachea particularly) ( Figures 4-3 and 4-6 to 4-10 ), air-fluid levels suggesting abscess, and radiopaque foreign bodies ( Figures 4-11 to 4-15 ), as all of these involve a contrast between two key tissue densities. (radiologykey.com)
  • Unfortunately, many of the soft-tissue abnormalities of interest to us as emergency physicians may not involve such a contrast. (radiologykey.com)
  • Instead, one soft-tissue structure may abut a second soft-tissue structure, and these are indistinguishable on x-ray. (radiologykey.com)
  • Examples include vascular dissections, abscesses, and subtle soft-tissue masses that may not be seen on x-ray. (radiologykey.com)
  • A soft-tissue neck series consists of an anterior-posterior (AP) (A) and a lateral (B) x-ray of the neck. (radiologykey.com)
  • Compared with a cervical spine x-ray, the images are intentionally underexposed to allow soft tissues to be examined. (radiologykey.com)
  • The most common locations are soft tissues and it presents as asymptomatic papule or nodule red. (bvsalud.org)
  • DSRCT was first described by Gerald and Rosai in 1989 as a primitive neoplasm of children and young adults that most frequently occurs in the serosa of the pelvic cavity. (medscape.com)
  • Reactive angioendotheliomatosis (RAE) is a benign cutaneous vascular disorder characterized by a distinct histologic and clinical appearance. (thedoctorsdoctor.com)
  • Histopathologically, it is characterized by a proliferation of endothelial cells within vascular lumina resulting in the obliteration of the involved vessels. (thedoctorsdoctor.com)
  • Of importance is the normal appearance of the most superficial epidermal layer on the far left, which was overlying the dermal layer, which contained a cellular infiltrate, and a proliferation of vascular elements. (cdc.gov)
  • New abnormal growth of tissue. (lookformedical.com)
  • Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. (lookformedical.com)
  • Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
  • They also may be produced through manipulation of lesions or processing of tissue or secretions in the hospital or laboratory. (cdc.gov)
  • His other principal written efforts include: Untersuchungen über pathologische Bindegewebs- und Gefässneubildung, 1876 - Pathological investigations of connective tissue and vascular neoplasms. (wikipedia.org)
  • The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. (lookformedical.com)
  • The course therefore aims to provide knowledge of the causes and mechanisms of the diseases and the alterations that derive from them at a tissue, cellular and molecular level. (uninsubria.eu)
  • Adenoma of the colon is a benign neoplasm of the large intestine, which creates the likelihood of developing cancer. (vsebolezni.com)
  • Adenoma of the stomach is a benign neoplasm in the stomach, which is of several types. (vsebolezni.com)
  • Tubular adenoma is a benign neoplasm of the large intestine, which occurs in almost half of the population older than 50 years. (vsebolezni.com)
  • The "endo-" of endosonography refers to the examination of tissue within hollow organs, with reference to the usual ultrasonography procedure which is performed externally or transcutaneously. (lookformedical.com)
  • The sectioned surface of the mass was multicystic and composed of numerous mucus-filled cystic locules and spongy to almost solid tissue. (hindawi.com)
  • A few notes on each cancer site and its subgroups staining techniques (e.g., glandular and diffuse neoplasms of are included in this chapter. (who.int)
  • It should be noted that the vast majority of neoplasms of the upper aerodigestive tract are epithelial and that some of these can show a spindle cell phenotype, e.g., spindle cell or sarcomatoid carcinoma and myoepitheliomas. (basicmedicalkey.com)
  • It is unclear whether the epithelioid hemangioendothelioma is truly neoplastic or an exuberant tissue reaction, nor is it clear if this is equivalent to Kimura's disease (see ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA). (uchicago.edu)
  • Epithelioid hemangioendothelioma (EHE) is a rare and slow-growing malignant vascular neoplasm composed of epithelioid endothelial cells within a distinctive myxohyaline stroma. (springeropen.com)
  • A benign focal growth composed of vascular tissue. (mcw.edu)
  • Загальні відомості про мієлопроліферативні захворювання Myeloproliferative neoplasms are clonal proliferations of bone marrow stem cells, which can manifest as an increased number of platelets, red blood cells (RBCs), or white blood cells (WBCs). (msdmanuals.com)
  • The neoplasms may be histologically the same or different, and may be found in the same or different sites. (lookformedical.com)
  • Kidney cancer is a histologically different variant of malignant neoplastic transformation of renal tissue. (medic-journal.com)
  • However, these neoplasms have a distinct nodular appearance without abundant lymphocytes and plasma cells typically seen in Hashimoto thyroiditis. (cap.org)
  • Neoplasms composed of primordial GERM CELLS of embryonic GONADS or of elements of the germ layers of the EMBRYO, MAMMALIAN. (sdsu.edu)
  • справжня поліцитемія Polycythemia vera is a chronic myeloproliferative neoplasm characterized by an increase in morphologically normal red cells (its hallmark), but also white cells and platelets. (msdmanuals.com)
  • Indeed, it is thought that RAE could be caused by ischemia secondary to vascular obstruction. (thedoctorsdoctor.com)
  • Any discussion of neoplasms or other masses found within the mediastinum requires delineation of the boundaries of that area. (medscape.com)
  • Another rare variant of reactive angioendotheliomatosis has been described in the lower extremities of patients with severe peripheral vascular atherosclerotic disease. (thedoctorsdoctor.com)