• A fibrous tissue neoplasm is a tumor derived primarily from Fibrous connective tissue. (wikipedia.org)
  • Histology reveals mature adipocytes and fibrous connective tissue infiltrating the space between the nerve fascicles. (tidsskriftet.no)
  • Sections show fibrous connective tissue with dissecting pools of mucin associated with scanty strips of malignant glandular epithelium in keeping with metastatic mucinous adenocarcinoma. (cancer.org)
  • SFTs of the pleura are localized mesenchymal neoplasms composed of fibroblastlike cells believed to arise from the subpleural connective tissue. (medscape.com)
  • Histologically, the tumor cells had granular or clear amphophilic cytoplasm with an oval nucleus and nests of cells delimited by connective tissue and vascular septations. (biomedcentral.com)
  • The histology showed a well differentiated malpighian epithelium on a richly vascularised connective tissue containing histiocytes, lymphocytes and plasmocytes. (ispub.com)
  • Because of its histological characteristics, abundance of connective and secondary changes/atrophy, fibrolipoma may appear as infiltrating adjacent tissues and may cause doubts of differential diagnosis with malignant infiltrating lesions. (springer.com)
  • 1. A tumor composed of connective tissue containing glandular structures. (wordquests.info)
  • Acute inflammation of a gland and the adjacent connective tissue. (wordquests.info)
  • Histological sections revealed presence of mucosal fragments with atrophic squamous stratified epithelium, and fibrous connective tissue composed of cells with granular and eosinophilic cytoplasm. (bvsalud.org)
  • connective tissue tumor is a neoplasm arising from the tissues of the connective tissue . (ipfs.io)
  • Not all tumors in the connective tissue are of the connective tissue. (ipfs.io)
  • Benign tumors typically have an outer fibrous sheath of connective tissue and grow more slowly than malignant tumors. (westernanimalhosp.com)
  • PMF is characterized by proliferation predominantly of bone marrow megakaryocytes and granulocytes, resulting in deposition of fibrous connective tissue, and often associated with peripheral blood leukoerythroblastosis, cytopenias, and constitutional symptoms. (oncohemakey.com)
  • The mouth is lined by stratified squamous epithelium overlying richly vascular connective tissue. (clinicalgate.com)
  • During its growth, a myoma compresses the surrounding structures (the myometrium and connective tissue), causing the progressive formation of a sort of pseudocapsule, rich in collagen fibers, neurofibers and blood vessels (Fig .1). (ijfs.ir)
  • The mass was suggested as a soft tissue tumor by computed tomographic (CT) examination. (thieme-connect.de)
  • Benign fibrous histiocytoma is a benign tumor composed of a mixture of fibroblastic and histiocytic cells. (alliedacademies.org)
  • The most important diagnostic distinction is the separation of this tumor from aggressive forms of fibrohistiocytic neoplasms like dermatofibrosarcoma protuberans and malignant fibrous histiocytoma. (alliedacademies.org)
  • Moreover, the fibrous nature of the tumor has given rise to various other names, such as pleural fibroma, submesothelial fibroma, and localized fibrous tumor. (medscape.com)
  • The currently accepted nomenclature is solitary fibrous tumor. (medscape.com)
  • Lipoma is a benign tumor most frequently found in almost all anatomical sites that have adipose tissue in their structure. (springer.com)
  • Once developed, the abnormal growth is called a neoplasm or tumor. (westernanimalhosp.com)
  • Benign and malignant tumours A benign tumor is a mass of cells that lacks the ability to invade neighboring tissue or spread throughout the body. (westernanimalhosp.com)
  • Diagnosing non-epithelial malignancies in effusion specimens based entirely upon their cytomorphologic features is difficult because these neoplasms often exhibit considerable morphological overlap and their cytomorphology can differ from the original tumor. (cytojournal.com)
  • Wilms tumor is believed to arise from embryonic tissues called nephrogenic rests that fail to undergo normal involution ( 7 ). (abdominalkey.com)
  • The tumor is usually circumscribed by a pseudocapsule formed of compressed renal and perirenal tissues. (abdominalkey.com)
  • 1,2) Nuclear expression of STAT6 is found in nearly all cases of solitary fibrous tumor (SFT) and is very limited in other soft tissue neoplasms making it a highly sensitive and specific immunohistochemical marker for SFT and may help to distinguish this tumor type from histologic mimics. (biocare.net)
  • Meningeal solitary fibrous tumor/hemangiopericytoma: Emphasizing on STAT 6 immunohistochemistry. (biocare.net)
  • Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics. (biocare.net)
  • Primary myelofibrosis, also known as idiopathic myelofibrosis and agnogenic myeloid metaplasia, is a malignant disease, one of the chronic myeloproliferative neoplasms, along with polycythemia vera and essential thrombocythemia, amongst others (see table 1). (fcarreras.org)
  • This genetic alteration is not hereditary (it is not transmitted from parents to their offspring), although some families have a predisposition to develop myeloproliferative neoplasms. (fcarreras.org)
  • Myeloproliferative neoplasms are caused by genetic mutations. (msdmanuals.com)
  • 10. Which of the following is a common finding in myeloproliferative neoplasms (MPNs)? (medicalbiochemist.com)
  • The chronic myeloproliferative neoplasms (MPNs) are clonal disorders characterized by overproduction of mature myeloid cells. (oncohemakey.com)
  • Mutations in TET2, other epigenetic regulators, and other regulators of cytokine signaling are not specific to the classic myeloproliferative neoplasms (MPNs) but may influence prognosis and play roles in hematopoietic stem cell (HSC) dysregulation and progression to accelerated or blast-phase disease. (oncohemakey.com)
  • Secondary myelofibrosis, also known as secondary myelofibrosis or post-polycythemia vera/essential thrombocythemia myelofibrosis, is a condition that occurs as a progression of two other myeloproliferative neoplasms (MPNs) called polycythemia vera (PV) and essential thrombocythemia (ET). (latestsharenews.com)
  • Polycythemia Vera Polycythemia vera is a myeloproliferative neoplasm of the blood-producing cells of the bone marrow that results in overproduction of all types of blood cells. (merckmanuals.com)
  • The term fibroma is inappropriate because the neoplasm exhibits defined histologic features that differ from those of fibromas and may express malignant behavior. (medscape.com)
  • for example, a benign fibrous neoplasm would be termed fibroma, and a benign glandular epithelium termed an adenoma. (mhmedical.com)
  • We present two clinical cases of patients aged 36 and 74 with an orbital solitary fibrous tumour (SFT). (scitechnol.com)
  • Solitary fibrous tumour (SFT) is an uncommon neoplasm at the orbital level that behaves in benign way in most cases [ 1 ]. (scitechnol.com)
  • A benign neoplasm composed of glandular and fibrous tissues , with a relatively large proportion of glands. (lookfordiagnosis.com)
  • A malignant neoplasm of epithelial cells in glandular or glandlike pattern. (wordquests.info)
  • Separation or ectopia of glands or glandular tissue from their usual anatomical sites, e.g., pancreatic glands in the wall of the small intestine, gastric glands in the wall of the esophagus. (wordquests.info)
  • Originating from glandular tissue. (wordquests.info)
  • A benign neoplasm composed of glandular and adipose tissues. (wordquests.info)
  • A few notes on each cancer site and its subgroups staining techniques (e.g., glandular and diffuse neoplasms of are included in this chapter. (who.int)
  • Primary myelofibrosis is characterised by the presence of a fibrous tissue in the bone marrow, and by the migration of bone marrow stem cells to the blood, where they colonise organs from a distance (mainly the spleen and the liver). (fcarreras.org)
  • and neoplasm = new abnormal growth, such as a precancer or cancer), the blood-producing cells in the bone marrow (precursor cells, also called stem cells) develop and reproduce excessively or are crowded out by an overgrowth of fibrous tissue. (msdmanuals.com)
  • Odontogenic keratocyst is an aggressive cyst known for its rapid growth and its tendency to invade the adjacent tissues, including bone. (washington.edu)
  • larger OKCs tend to expand bone, but mildly- obvious clinical expansion (which is the case in this patient) should be viewed with suspicion for a neoplasm . (washington.edu)
  • however, they constitute 2-4% of all primary bone neoplasms. (spinalsurgerynews.com)
  • Myelofibrosis is characterized by the excessive production of fibrous tissue in the bone marrow, leading to impaired blood cell production. (latestsharenews.com)
  • Aneurysmal bone cyst is designated as an uncommon, expansive, benign, osteolytic lesion delineating blood-filled spaces of variable magnitude demarcated by fibrous tissue septa and intermingled with osteoclast-like giant cells along with reactive bone. (actascientific.com)
  • Aneurysmal bone cyst is a non-malignant neoplasm simulating vascular lesions denominated by blood- filled vascular channels. (actascientific.com)
  • Myelofibrosis Myelofibrosis is a disorder in which fibrous tissue in the bone marrow replaces the blood-producing cells, resulting in abnormally shaped red blood cells, anemia, and an enlarged spleen. (merckmanuals.com)
  • It differs from bone, however, in that its cellular constituents (odontoblasts) form a layer over the surface of the dentine, from which long tubular processes ramify through the tissue. (clinicalgate.com)
  • Bone Marrow Biopsy removal of aspirate and solid tissue from marrow for analysis. (mpninfo.org)
  • Histopathology demonstrated irregular lamellar bone with hypocellular fibrous stroma, but no obvious atypia, mitotic activity or necrosis mimicking fibrous dysplasia (Figure 3A). (medscape.com)
  • Microscopically, the cervical stroma is composed of an admixture of fibrous, muscular (15%), and elastic tissue. (medscape.com)
  • DSRCT is composed of small cells with round hyperchromatic nuclei and a dense fibrous or spindle cell stroma. (medscape.com)
  • Histologically, masses and nodules consisted of a collagen-rich fibrous stroma with multifocal areas of increased cellularity represented by spindle cell proliferations with moderate lymphoplasmacellular infiltrates ( Figure 1 , panel C). The tonsils and mandibular and axillary lymph nodes showed similar foci of fibrovascular tissue. (cdc.gov)
  • It is a slow-growing, persistent, and locally aggressive neoplasm of epithelial origin. (washington.edu)
  • Malignant neoplasms from epithelial origin are called carcinoma while those derived from mesenchymal origin are referred to as sarcoma. (mhmedical.com)
  • While most tumors metastatic to the serous membranes are of epithelial origin, cytologists should be aware that non-epithelial neoplasms can also cause malignant effusions including sarcomas, melanomas, germ cell tumors, and, more rarely, brain tumors. (cytojournal.com)
  • Endoscopic ultrasonography-guided fine-needle aspiration revealed CD34-positive spindle-shaped cells in the fibrous tissue, suggestive of a mesenchymal neoplasm. (biomedcentral.com)
  • Lipoblastoma is an exceptional, benign, lobulated, mesenchymal neoplasm arising from embryonal adipose tissue cells or lipoblasts or immature adipocytes. (lupinepublishers.com)
  • As a lobulated, mesenchymal neoplasm comprised of embryonal or foetal adipose tissue, lipoblastoma, characteristically demonstrates a benign biological behaviour, preliminary discernment, male predominance and brisk tumour evolution. (lupinepublishers.com)
  • Desmoid tumors are cytologically bland fibrous neoplasms originating from the musculoaponeurotic structures throughout the body. (medscape.com)
  • Desmoid tumors often appear as infiltrative, usually well-differentiated, firm overgrowths of fibrous tissue, and they are locally aggressive. (medscape.com)
  • This course and the tendency for recurrence make the treatment of these relatively rare fibrous tumors challenging. (medscape.com)
  • Based on the location of these tumors are usually divided into cutaneous types and those involving deep tissues. (alliedacademies.org)
  • Desmoid tumors are associated with a biallelic APC mutation in the affected tissue. (medscape.com)
  • Malignant tumors usually grow more aggressively, they invade the tissues surrounding them and can metastasize (spread throughout the body). (westernanimalhosp.com)
  • Common non-epithelial neoplasms that may cause malignant effusions include malignant melanoma, sarcomas, and other neoplasms including germ cell tumors [ Figure 1 ]. (cytojournal.com)
  • All categories of soft tissue tumors have been reported to involve the upper aerodigestive tract. (basicmedicalkey.com)
  • These tumors have markedly different prognoses and require different treatments than those for soft tissue tumors. (basicmedicalkey.com)
  • Fibroblastic or myofibroblastic tumors make up the majority of soft tissue tumors of the aerodigestive tract and range from nonneoplastic or benign proliferations (fibromas) to high-grade malignancies (undifferentiated high-grade pleomorphic sarcomas). (basicmedicalkey.com)
  • Three months later, follow-up radiographs demonstrated changes consistent with a more aggressive neoplasm. (medscape.com)
  • The diagnosis of benign fibrous histiocytoma located in the deeper tissues is clinically difficult and is confirmed histopathologically after excision. (alliedacademies.org)
  • Because of this, one should be comfortable using immunohistochemistry or other methods with the diagnosis of these lesions, and to help exclude epithelial or melanocytic neoplasms ( Table 11.1 ). (basicmedicalkey.com)
  • This is a unique case due to the low frequency 2 , the atypical clinical history, but mainly the difficult histopathological differential diagnosis and immunohistochemical evaluation among these neoplasms. (bvsalud.org)
  • A variety of benign fibrous lesions that may or may not be neoplastic can be found within the upper aerodigestive tract and have been termed "fibromas. (basicmedicalkey.com)
  • Primary malignant neoplasms of the sweat glands are rare, constituting less than 1% of all primary malignant skin lesions 1 . (bvsalud.org)
  • Lipofibromatous hamartoma is a rare but benign neoplasm of peripheral nerves. (tidsskriftet.no)
  • In chronic alveolar hydatid infections, the lesion consists of a central necrotic cavity filled with a white amorphous material that is covered with a thin peripheral layer of dense fibrous tissue. (cdc.gov)
  • Ameloblastoma is one of the most common benign neoplasms of odontogenic origin. (washington.edu)
  • Myomas are the most common benign neoplasm of the reproductive organs in women of reproductive age. (ijfs.ir)
  • A limited battery of immunoperoxidase stains (with appropriate positive and negative controls) was performed to determine the likely primary site for this malignant neoplasm. (cancer.org)
  • Metastases are secondary growths of cells from the primary neoplasm. (mhmedical.com)
  • In secondary echinococcosis, larval tissue spreads from the primary site and new cysts develop after spontaneous or trauma-induced cyst rupture or after release of viable parasite material during invasive treatment procedures. (cdc.gov)
  • Given these results, the authors discuss the difficulty in diagnosing differentiation from a primary or metastatic neoplasm of the scalp, with the resources currently available, until the conclusion that it was a primary carcinoma of the sweat gland. (bvsalud.org)
  • Local recurrence results in tissue destruction and generally is the cause of death. (spinalsurgerynews.com)
  • As far as possible, treatment involves complete resection as the presence of remnants of intraorbital tumour tissue after the operation carries the risk of causing recurrence of the tumour and can even undergo transformation by becoming malignant [ 3 ]. (scitechnol.com)
  • Even though chordomas usually are slow-growing tumours, they are locally aggressive with a tendency to infiltrate into adjacent tissues and organs. (spinalsurgerynews.com)
  • Additional tissue samples from other organs such as the lymph nodes may be necessary to determine the rate and extent of spread of a malignant neoplasm. (westernanimalhosp.com)
  • Kaposi's sarcoma herpesvirus (KSHV), a member of the genus Rhadinovirus , is the causative agent of Kaposi sarcoma ( 1 ), an endothelial neoplasm of the dermis, oral cavity and intestinal organs. (cdc.gov)
  • By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
  • It should be noted that the vast majority of neoplasms of the upper aerodigestive tract are epithelial and that some of these can show a spindle cell phenotype, e.g., spindle cell or sarcomatoid carcinoma and myoepitheliomas. (basicmedicalkey.com)
  • Tissue alterations due to these atrophic changes, trauma, erythema, and microvascularization can be confused with cervical intraepithelial neoplasia. (medscape.com)
  • Neoplasia is defined as new growth or autonomous growth of tissue. (mhmedical.com)
  • However, it is generally recognized that neoplasia is the uncontrolled, abnormal growth of cells or tissues in the body, prior to a lump or abnormal growth developing. (westernanimalhosp.com)
  • The word "cancer" is often used instead of neoplasia, but only malignant neoplasms are true cancers. (westernanimalhosp.com)
  • Pre-treatment biopsy demonstrates bland spindle cell proliferation and irregular bony trabeculae resembling fibrous dysplasia. (medscape.com)
  • After detailed clinical and laboratory examinations, the lesion was excised in toto under general anesthesia, and histopathology revealed it to be a benign fibrous histiocytoma. (alliedacademies.org)
  • Malignant fibrous histiocytoma c. (dentaldevotee.com)
  • The correct answer is: B. Malignant fibrous histiocytoma. (dentaldevotee.com)
  • Fibrous histiocytoma: Storiform pattern (helicopter in wheat field) is seen. (dentaldevotee.com)
  • Generally, kidney tumours originate from the proliferation of malignant cells within the renal tubules (or nephrons), or they are neoplasms from the fibrous tissues (that cover the organ itself). (lugnani.com)
  • Another aspect that brings cryoablation to the forefront as a surgical choice, is the possibility of keeping and maintaining a larger quantity of renal tissue: in fact there is no need to comply with the same oncological safety margins required when operating with a scalpel. (lugnani.com)
  • A neoplastic lesion is referred to as a neoplasm ( Table 8-1 ). (mhmedical.com)
  • It accounts for only 0.8 to 1% of all cancers and represents 1 to 1.8% of superficial soft tissue sarcomas. (thieme-connect.de)
  • Other cases are generally sarcomas in various forms, dependent upon the tissue in which they originate. (lugnani.com)
  • However, these neoplasms have a distinct nodular appearance without abundant lymphocytes and plasma cells typically seen in Hashimoto thyroiditis. (cap.org)
  • Histopathology demonstrated monomorphic fusiform cell neoplasm, in a "swirled" focal arrangement, infiltrative of dermal tissue, compatible with DFSP. (thieme-connect.de)
  • In contrast, lipoblastomatosis is a poorly defined, non-encapsulated, multi-centric, infiltrative, generally deep- seated neoplasm composed of an accumulation of foetal adipose tissue. (lupinepublishers.com)
  • Fibrolipoma excision, like that described in this report, sometimes may be laborious, because fibrous bands appear to be focally infiltrating adjacent tissues, giving rise to some doubts about the nature of the lesion. (springer.com)
  • However, in some situations, infiltration of the tumour requires more extensive resection of adjacent tissues. (scitechnol.com)
  • In the Computed tomography (CT), the presence of a well-defined lesion with nodular morphology, located in the anterior extraconal space in the superior medial margin of the left orbit, without visible calcifications in the inner part or signs of infiltration into the adjacent tissues was observed. (scitechnol.com)
  • A neoplasm is defined as a heritably altered, relatively autonomous growth of tissue with abnormal regulation of gene expression. (mhmedical.com)
  • and neoplasm = new abnormal growth, such as a precancer or cancer), the blood-producing cells in the. (merckmanuals.com)
  • In some cases, taking a tissue sample (biopsy) from the neoplasm for microscopic examination may also be necessary. (westernanimalhosp.com)
  • Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. (medscape.com)
  • Host tissue is directly invaded by extension of the budding and proliferating cyst wall, causing a pressure necrosis of surrounding host tissue. (cdc.gov)
  • As lipoblastoma arises from embryonic adipose tissue, it is additionally nomenclated as "embryonic lipoma or foetal or embryonal lipoblastoma" [1]. (lupinepublishers.com)
  • when used in the plural, adenoids, they refer to lymphoid tissue that normally exists in the nasopharynx of children and is known in medicine as the pharyngeal tonsil. (wordquests.info)
  • growth of lymphoid tissue in the upper part of the throat, behind the nose (they can swell up and obstruct breathing and speaking). (wordquests.info)
  • The most recognized subtype is the fibrous variant of Hashimoto thyroiditis, which is characterized by marked fibrous replacement of the thyroid parenchyma and microscopic changes typical of Hashimoto thyroiditis in the remaining tissue. (cap.org)
  • Dermatofibrosarcoma protuberans (DFSP) is an uncommon, painless, slow-growth, superficial soft tissue malignant sarcoma corresponding to less than 0.1% of all malignancies. (thieme-connect.de)
  • Intraoperatively, the excision was more laborious at some points because fibrous bands appeared to be focally infiltrating surrounding tissues, and the neoformation was hard to detach (giving rise to some doubts about the nature of the lesion). (springer.com)
  • Dermatofibrosarcoma protuberans (DFSP) is a rare superficial and uncommon low-grade soft tissue malignant sarcoma that is locally invasive and often characterized as a keloid sarcoma. (thieme-connect.de)
  • Discussion Orbital SFT is a generally benign neoplasm originating from the mesenchyme, uncommon in the orbit. (scitechnol.com)
  • A predominantly lobulated, well circumscribed, encapsulated tumefaction simulating foetal adipose tissue, lipoblastoma is commonly situated within subcutaneous tissue. (lupinepublishers.com)
  • Essentially comprised of immature, persistent, embryonic adipose tissue which proliferates rapidly within the post natal period, lipoblastoma can configure an enlarged tumefaction wherein the variable tumour magnitude can extend up to 25 centimetres [3,4]. (lupinepublishers.com)
  • Lipoblastoma is commonly observed within sites of persistent immature adipose tissue. (lupinepublishers.com)
  • Lipoblastoma can simulate foetal adipose tissue aggregates or a myxoid liposarcoma. (lupinepublishers.com)