MyeloproliferativeBone Marrow TransplaLiver NeoplasmsTumorMalignantHematopoieticBlastic plasmacytoid dendritic celKidney transplantationLymphomaHematologyAcute myeloidPancreatic Neuroendocrine NeoplasmsOrthotopic liver transplantation2022ComplicationsMetastatic neoplasmMalignanciesStemMyeloidRecurrenceImmunosuppressivePatientsLymphoproliferative disordersCarcinomaMeSHBenignOrganExperimentalVisceralLungClonalHepatic artery2021LiposarcomaPrimaryNeoplasiaChronicClinical TrialTreatment approaches
Myeloproliferative20
- The purpose of this research study is to test the safety and efficacy of cytokine induced memory-like (CIML) natural killer (NK) cells expanded with Interleukin-2 (IL-2) at preventing relapse in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or MDS and myeloproliferative neoplasm (MPN) overlap syndrome after a standard-of-care stem cell transplant. (survivornet.com)
- This is a phase I/Ib study of the pre-emptive treatment using related donor-derived cytokine induced memory-like (CIML) natural killer (NK) cells combined with Interleukin-2 (IL-2) for participants with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and MDS/myeloproliferative neoplasm (MDS/MPN) overlap syndrome at high risk for post-allogeneic stem cell transplant (SCT) relapse. (survivornet.com)
- His clinical interests include multiple myeloma, stem cell transplantation, and myeloproliferative neoplasm. (aamds.org)
- Research interests are targeted therapy in CML and myeloproliferative neoplasms. (aamds.org)
- His particular interest is in transplantation for multiple myeloma, lymphoma, myelodysplastic syndrome, acute leukemia and myeloproliferative neoplasms. (lvhn.org)
- Myelofibrosis (MF) is a hematopoietic stem cell malignancy classified as a myeloproliferative neoplasm (MPN). (cancernetwork.com)
- The myeloproliferative neoplasms (MPNs) are a heterogeneous group of chronic hematological malignancies that are generally divided into the Philadelphia chromosome-positive (Ph-positive) MPNs, which refers to chronic myelogenous leukemia (CML) and the Philadelphia chromosome-negative (Ph-negative) MPNs. (cancernetwork.com)
- Cancer Care provides free, professional support services for people affected by myeloproliferative neoplasms, as well as treatment information and financial help with cancer-related costs and treatment co-pays. (cancercare.org)
- Oncology social workers help you cope with the emotional and practical challenges of myeloproliferative neoplasms. (cancercare.org)
- She is board certified in hematology and medical oncology with expertise in Malignant Hematology including Lymphoproliferative neoplasms, Myeloproliferative neoplasms, Acute Leukemia, Multiple Myeloma and interest in Stem Cell transplantation. (ca.gov)
- Neoplasms originating from the blood or bone marrow (leukemias and myeloproliferative disorders) are not considered solid tumors. (mycancergenome.org)
- JAK2 rs10974944 is associated with both V617F-positive and negative myeloproliferative neoplasms in a Vietnamese population: A potential genetic marker. (cdc.gov)
- The differences of hemogram, myelogram, and driver gene mutations in classic myeloproliferative neoplasms. (cdc.gov)
- Development of a Real-Time qPCR Assay for Detection of Common MPL Mutations in Myeloproliferative Neoplasms (MPNS). (cdc.gov)
- Vascular Endothelial Dysfunction in Myeloproliferative Neoplasms and Gene Mutations. (cdc.gov)
- Study of CALR, MPL, and c-kit Gene Mutations in Thai Patients with JAK2 V617F Negative Myeloproliferative Neoplasms. (cdc.gov)
- Analysis of DNA Methylation Gene Mutations and Clinical Features in Patients with Myeloproliferative Neoplasm]. (cdc.gov)
- The clinical relevance of broad mutational screening of myeloproliferative neoplasms at diagnosis. (cdc.gov)
- Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by bone marrow fibrosis, splenomegaly, and anemia with nucleated and teardrop-shaped red blood cells. (msdmanuals.com)
- Overview of Myeloproliferative Neoplasms Myeloproliferative neoplasms are clonal proliferations of bone marrow stem cells, which can manifest as an increased number of platelets, red blood cells (RBCs), or white blood cells (WBCs). (msdmanuals.com)
Bone Marrow Transpla2
- Bone marrow transplantation , 33 (12), 1215-1218. (elsevierpure.com)
- She is a member of The American Society of Hematology, the American Board of Internal Medicine, the American Society of Clinical Oncology and the American Society of Blood and Bone Marrow Transplantation. (ca.gov)
Liver Neoplasms1
- Percutaneous ethanol injection (PEI) for liver neoplasms when criteria above are not met. (aetna.com)
Tumor6
- The original procedure involved en bloc removal of a tumor together with the intestine , ex vivo resection and reconstruction of gastrointestinal tract by an intestinal autograft . (bvsalud.org)
- Secondary neoplasm refers to any of a class of cancerous tumor that is either a metastatic offshoot of a primary tumor, or an apparently unrelated tumor that increases in frequency following certain cancer treatments such as chemotherapy or radiotherapy. (wikipedia.org)
- In modern English, tumor is used as a synonym for neoplasm (a solid or fluid-filled cystic lesion that may or may not be formed by an abnormal growth of neoplastic cells) that appears enlarged in size. (wikipedia.org)
- Some neoplasms do not form a tumor - these include leukemia and most forms of carcinoma in situ. (wikipedia.org)
- Nonfunctioning neuroendocrine neoplasms can still cause symptoms relating to tumor size and location such as obstruction or internal bleeding. (rarediseases.org)
- Tumor glucose use in patients with non-islet-cell tumors has been difficult to measure, particularly in hepatoma, because of hepatic involvement by neoplasm. (jci.org)
Malignant10
- ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. (wikipedia.org)
- Malignant neoplasms are also simply known as cancers and are the focus of oncology. (wikipedia.org)
- A neoplasm can be benign, potentially malignant, or malignant (cancer). (wikipedia.org)
- Potentially-malignant neoplasms include carcinoma in situ. (wikipedia.org)
- Malignant neoplasms are commonly called cancer. (wikipedia.org)
- However, our search of the literature did not produce a significant volume of literature, or literature of sufficiently sound methodology, to permit our staff to make a determination regarding liver transplantation for other malignant diagnoses, such as metastatic disease, bile duct carcinoma and epithelioid hemangioendothelioma. (cms.gov)
- The body of literature related to liver transplantation for patients with HCC includes several comparison studies of sufficient sample size to clearly establish patient outcomes comparable to liver transplantation for non-malignant conditions. (cms.gov)
- The purpose of the technology assessment is to provide information to assist HCFA in determining whether there is sufficient evidence to conclude whether liver transplantation for malignant diseases other than HCC meets the criteria of being reasonable and necessary under the Medicare law. (cms.gov)
- A benign or malignant neoplasm arising from tissues that do not include fluid areas. (mycancergenome.org)
- Lymphoma is a malignant neoplasm that develops in the lymph nodes. (bvsalud.org)
Hematopoietic7
- Retrospective analysis by the Center for International Blood and Marrow Transplant Research (CIBMTR): Prompt complete remission plus consolidation therapy yields improved survival after allogeneic hematopoietic cell transplantation (allo-HCT) for patients with acute myeloid leukemia (AML) receiving a myeloablative conditioning regimen and not a reduced-intensity conditioning regimen. (ascopost.com)
- Outcomes of Allogeneic Hematopoietic Cell Transplantation (Allo-HCT) in Patients with CALR-Mutated Myelofibrosis compared to those patients with a JAK2-mutation. (ebmt.org)
- He has published extensively on the immunobiology and application of hematopoietic cell transplantation, with nearly 200 scientific abstracts and peer-reviewed publications over the span of his career. (lvhn.org)
- Scholars@Duke publication: CT-039 Health-Related Quality of Life Following Allogeneic Hematopoietic Stem Cell Transplantation With Omidubicel Versus Standard Umbilical Cord Blood. (duke.edu)
- CONTEXT: Omidubicel is an ex vivo expanded stem cell product derived from umbilical cord blood (UCB) for allogeneic hematopoietic stem cell transplantation (allo-HSCT). (duke.edu)
- Hematopoietic stem cell transplantation is the only potentially curative therapy, but it is only an option for select patients. (cancernetwork.com)
- Cbl0137, cudc-907, and allogeneic hematopoietic stem cell transplantation are the most common interventions in solid neoplasm clinical trials. (mycancergenome.org)
Blastic plasmacytoid dendritic cel3
- Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive disease with historically poor outcomes. (medpagetoday.com)
- For years the disease known as BPDCN had many different names, including natural killer cell leukemia/lymphoma, and only with the discovery that the disease is derived from plasmacytoid dendritic cells was the term established as blastic plasmacytoid dendritic cell neoplasm by the World Health Organization in 2008, and listed as its own entity in 2016. (medpagetoday.com)
- Immunophenotypic and Molecular Features of Acute Myeloid Leukemia with Plasmacytoid Dendritic Cell Differentiation Are Distinct from Blastic Plasmacytoid Dendritic Cell Neoplasm. (atlasgeneticsoncology.org)
Kidney transplantation5
- To describe the clinical response, overall and graft survival of patients in our center with this complication after kidney transplantation, which received rituximab as part of their treatment as well as conversion to m-TOR. (univalle.edu.co)
- Retrospective study, which included patients, diagnosed with post-transplant lymphoproliferative disorders after kidney transplantation from January 2011 to July 2014. (univalle.edu.co)
- There are no standardized treatment regimens for lymphoproliferative disorders after kidney transplantation, but these patients can be managed successfully with reduction of immunosuppression, conversion to m-TOR and rituximab-based schemes. (univalle.edu.co)
- Apart from the current case, a case of eruptive syringoma that developed after kidney transplantation has been reported (6). (medicaljournals.se)
- Tzvetanov I, Spaggiari M, Jeon H, Roca RG, Bhati C, Oberholzer J, Benedetti E.&The role of splenectomy in the setting of refractory humoral rejection after kidney transplantation. (uic.edu)
Lymphoma1
- For lymphoid neoplasms, e.g. lymphoma and leukemia, clonality is proven by the amplification of a single rearrangement of their immunoglobulin gene (for B cell lesions) or T cell receptor gene (for T cell lesions). (wikipedia.org)
Hematology1
- To complement The ASCO Post 's continued comprehensive coverage of the 2021 American Society of Hematology (ASH) Annual Meeting & Exposition, here are several abstracts selected from the meeting proceedings focusing on allogeneic transplantation for hematologic neoplasms in adults. (ascopost.com)
Acute myeloid1
- I have expertise in novel therapies for acute myeloid leukemia, stem cell mobilization and homing, as well as stem cell transplantation. (rochester.edu)
Pancreatic Neuroendocrine Neoplasms1
- Pancreatic neuroendocrine neoplasms (pNENs) are an increasingly common group of malignancies that arise within the endocrine tissue of the pancreas. (rarediseases.org)
Orthotopic liver transplantation3
- Spectral Doppler ultrasonographic waveform of the right hepatic artery in a 60-year-old man, 8 years after orthotopic liver transplantation. (medscape.com)
- Pre-operative hepatic artery chemoembolization followed by orthotopic liver transplantation for HCC. (aetna.com)
- Pre-operative use as a bridge to orthotopic liver transplantation for HCC. (aetna.com)
20221
- International journal of organ transplantation medicine 2022 5 12 (3): 12-20. (cdc.gov)
Complications5
- See the images below of transplantation complications. (medscape.com)
- Lee et al retrospectively enrolled 75 patients who had undergone liver transpalantation and found that although MDCT in the late period should be interpreted with caution in patients with suspected biliary complication, MDCT is a reliable diagnostic technique for the identification of early and late abdominal complications after liver transplantation. (medscape.com)
- In addition toallograft rejection (a topic covered elsewhere in this series), a multitude of medical complications mark the post-transplantation course. (ersjournals.com)
- Post-transplantation lymphoproliferative disorders are serious complications of organ transplantation which treatment is not yet standardized. (univalle.edu.co)
- Within this observation period, no difference in the rate of these complications, including secondary neoplasms, was observed between patients treated with and without HD-ASCT. (lu.se)
Metastatic neoplasm1
- Rarely there can be a metastatic neoplasm with no known site of the primary cancer and this is classed as a cancer of unknown primary origin. (wikipedia.org)
Malignancies4
- Medicare conducted an analysis of the scientific evidence related to liver transplantation for patients with malignancies. (cms.gov)
- Attached is a request for a technology assessment that we need in order to develop a Medicare national coverage determination for liver transplantation for malignancies other than hepatocellular carcinoma. (cms.gov)
- Currently, Medicare national coverage policy for liver transplantation excludes coverage for all malignancies. (cms.gov)
- HCFA has determined that it does not possess sufficient internal expertise to fully and fairly review liver transplantation for these other malignancies, and that additional resources are required to facilitate this process. (cms.gov)
Stem6
- If there is no clinical evidence of a change in cardiovascular function from the time of pre-transplantation ECHO (per FACT standards should be performed within 6 weeks of stem cell infusion), then there is no need to repeat it. (survivornet.com)
- Dr. Scadden discusses which blood cancer patients are eligible for stem cell transplantation, as well as the latest advances in the field. (cancernetwork.com)
- Of these patients 45% went on to undergo stem-cell transplantation, and survival rates at 18 and 24 months were 59% and 52%, respectively. (medpagetoday.com)
- It is an honor to bring stem cell transplantation and cellular therapies to adults in the Lehigh Valley and its surrounding communities," Dr. Toor says. (lvhn.org)
- The aim of this population-based study was to describe the magnitude and panorama of late effects among patients treated with or without high-dose chemotherapy with autologous stem cell transplantation (HD-ASCT). (lu.se)
- Treatment is often supportive, but Janus kinase 2 (JAK2) inhibitors, such as ruxolitinib , fedratinib , or pacritnib, may decrease symptoms and stem cell transplantation may be curative. (msdmanuals.com)
Myeloid2
- Some case reports identified MYC or MLL gene amplification performing as dmin in myeloid neoplasms. (hindawi.com)
- FLT3 ( FMS -related tyrosine kinase 3) acts as an oncogene in myeloid neoplasms which is associated with several signal transduction pathways. (hindawi.com)
Recurrence1
- We studied a patient with nonhepatic recurrence of hepatoma after successful liver transplantation. (jci.org)
Immunosuppressive1
- Surgical advances, in conjunction with more effective immunosuppressive strategies, have propelled the field of lung transplantation forward and have made intermediate-term survival an achievable goal. (ersjournals.com)
Patients10
- [ 3 ] . An increasing number of orthotopic and living-donor liver transplantations are being performed to salvage patients with otherwise incurable end-stage liver disease (ESLD). (medscape.com)
- Intestinal autotransplantation has recently emerged in clinical practice as a treatment option for selected patients with neoplasms involving the SMA. (bvsalud.org)
- Patients with histiocytic neoplasms can now receive treatment with cobimetinib following its approval by the FDA. (cancernetwork.com)
- Oral MEK1/2 inhibitor cobimetinib (Cotellic) has received approval by the FDA for the treatment of patients with histiocytic neoplasms including Erdheim-Chester disease, Rosai-Dorfman disease, and Langerhans cell histiocytosis. (cancernetwork.com)
- Transplantation of patients with underlying cystic fibrosis (CF), whose native airways and sinuses are chronically infected with virulent bacterial pathogens, initially raised unique concerns about the potential excessive risk of postoperative infections. (ersjournals.com)
- Two recent series from North American centres with extensive experience in transplantation of CF patients have documented 1-yr survival rates of 50% versus 83% and 67% versus 96% among CF patients with and without B. cepacia , respectively 7 , 8 . (ersjournals.com)
- ABL1 is altered in 1.76% of solid neoplasm patients [ 2 ]. (mycancergenome.org)
- BCR is altered in 1.37% of solid neoplasm patients [ 2 ]. (mycancergenome.org)
- BRAF is altered in 6.45% of solid neoplasm patients [ 2 ]. (mycancergenome.org)
- NF1 is altered in 7.01% of solid neoplasm patients [ 2 ]. (mycancergenome.org)
Lymphoproliferative disorders1
- Treatment of post-transplantation lymphoproliferative disorders after kidney transplant with rituximab and conversion to m-TOR inhibitor. (univalle.edu.co)
Carcinoma2
- Not all types of neoplasms cause a tumorous overgrowth of tissue, however (such as leukemia or carcinoma in situ) and similarities between neoplasmic growths and regenerative processes, e.g., dedifferentiation and rapid cell proliferation, have been pointed out. (wikipedia.org)
- Representative examples include epithelial neoplasms (e.g. lung carcinoma, prostate carcinoma, breast carcinoma, colon carcinoma), and neoplasms arising from the soft tissues and bones (e.g. leiomyosarcoma, liposarcoma, chondrosarcoma, osteosarcoma). (mycancergenome.org)
MeSH1
- Neoplasm Transplantation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
Benign1
- A syringoma is a benign appendageal neoplasm that typically presents in adolescent females. (medicaljournals.se)
Organ1
- Transmission can also occur congenitally, via blood transfusion and organ transplantation, and by ingestion of food and drink contaminated with feces from infected bugs. (medscape.com)
Experimental1
- Experimental transplantation of neoplasms in laboratory animals for research purposes. (umassmed.edu)
Visceral1
- NORD gratefully acknowledges Simon Schimmack, MD, University Hospital of General, Visceral and Transplantation Surgery of Heidelberg, Germany, and Gastrointestinal Pathobiology Research Group, Department of Gastroenterological Surgery, Yale University School of Medicine, for assistance in the preparation of this report. (rarediseases.org)
Lung1
- Initial attempts to perform lung transplantation (LTx) were marred by technical limitations that often resulted in early postoperative death. (ersjournals.com)
Clonal1
- It is tempting to define neoplasms as clonal cellular proliferations but the demonstration of clonality is not always possible. (wikipedia.org)
Hepatic artery1
- A-1: Magnetic resonance angiogram in a transplantation patient with hepatic artery thrombosis. (medscape.com)
20211
- Uneétude descriptive, transversale portant sur les patientes traitées en radiothérapie à l'Hôpital Général de Douala pour cancer du col de l'utérus a été réalisée d'octobre 2020 à janvier 2021.Résultats. (bvsalud.org)
Liposarcoma1
- This report describes an unusual presentation of liposarcoma with concomitant relapse of underlying myelodysplasia developing in a patient 9 years after the first of two allogeneic transplantations. (elsevierpure.com)
Primary1
- In addition, relapse of primary myelodysplasia rarely occurs after 5 years from the time of allogeneic transplantation. (elsevierpure.com)
Neoplasia1
- The process that occurs to form or produce a neoplasm is called neoplasia. (wikipedia.org)
Chronic1
- Are next-generation sequencing results knocking on Heaven's door for transplantation planning in chronic myelomonocytic leukemia? (haematologica.org)
Clinical Trial1
- ABL1 is an inclusion eligibility criterion in 1 clinical trial for solid neoplasm, of which 0 are open and 1 is closed. (mycancergenome.org)