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  • allele
  • Piedmontese cattle carry a unique gene mutation identified as an inactive myostatin allele that causes hypertrophic muscle growth, or double muscling. (wikipedia.org)
  • Piedmontese cattle are distinguished by a unique, naturally occurring gene identified as the myostatin allele mutation, or inactive myostatin gene. (wikipedia.org)
  • Research indicates the presence of the myostatin allele mutation produces morphological characteristics unique to the breed, such as double-muscling, beef tenderness, reduced fat content and high yield. (wikipedia.org)
  • homozygous
  • However, the animal breeds developed as homozygous for myostatin deficiency have reproduction issues due to their unusually heavy and bulky offspring, and require special care and a more expensive diet to achieve a superior yield. (wikipedia.org)
  • cattle
  • Naturally occurring deficiencies of myostatin of various sorts have been identified in some breeds of cattle, sheep, whippets, and humans. (wikipedia.org)
  • After that discovery, several laboratories cloned and established the nucleotide sequence of a myostatin gene in two breeds of cattle, Belgian Blue and Piedmontese. (wikipedia.org)
  • While hypertrophic meat (e.g. from Piedmontese beef) has a place on the specialist market due to its unusual properties, at least for purebred myostatin-deficient strains the expenses and (especially in cattle) necessity of veterinary supervision place them at a disadvantage in the bulk market. (wikipedia.org)
  • Piedmontese beef is meat from cattle having one or two copies of the inactive myostatin gene. (wikipedia.org)
  • muscular
  • There is hope that studies into myostatin may have therapeutic application in treating muscle wasting diseases such as muscular dystrophy. (wikipedia.org)
  • The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development. (wikipedia.org)
  • residues
  • Human myostatin consists of two identical subunits, each consisting of 109 (NCBI database claims human myostatin is 375 residues long) amino acid residues [note the full length gene encodes a 375AA prepro-protein which is proteolytically processed to its shorter active form]. (wikipedia.org)
  • blocker
  • In a recent study just published in the peer-reviewed Journal of the American College of Nutrition, MYOS RENS product containing fertile egg yolk powder called Fortetropin®, the Company's proprietary myostatin blocker agent. (proteinfactory.com)