• Tissue
  • A myocyte (also known as a muscle cell) is the type of cell found in muscle tissue. (wikipedia.org)
  • However, smooth muscle tissue tends to demonstrate greater elasticity and function within a larger length-tension curve than striated muscle. (wikipedia.org)
  • With the myocardium now recognized as a tissue with limited regenerating potential, harbouring eCSCs that can be isolated and amplified in vitro for regenerative protocols of cell transplantation or stimulated to replicate and differentiate in situ in response to growth factors, it has become reasonable to exploit this endogenous regenerative potential to replace lost/damaged cardiac muscle with autologous functional myocardium. (wikipedia.org)
  • Specifically, in smooth muscle tissue, PKG promotes the opening of calcium-activated potassium channels, leading to cell hyperpolarization and relaxation, and blocks agonist activity of phospholipase C, reducing liberation of stored calcium ions by inositol triphosphate. (wikipedia.org)
  • airway smooth muscle
  • The control and mechanisms of airway smooth muscle cell (SMC) contraction were investigated with a sequential series of lung slices from different generations of the same airway from the cardiac lobe of the mouse lung. (umassmed.edu)
  • Transforming growth factor-B (TGF-B), found to be overexpressed in airway smooth muscle (ASM) from asthmatic and chronic obstructive pulmonary disease patients, may be a pivotal regulator of abnormal ASM cell (ASMC) function in these diseases. (edu.au)
  • antibodies
  • 118 kDa band in Western blots of homogenates of human aortic myocytes, whereas antibodies against residues 29-42 (nt 85-126) do not react with any bands in these homogenates. (lu.se)
  • Using two antibodies against different epitopes on smooth muscle myosin II (SMM), two distinct pools of SMM, diffuse, and stress-fiber-associated, were visualized by immunocytochemical staining. (pnas.org)
  • contractile
  • Each muscle fiber contains myofibrils, which are very long chains of sarcomeres, the contractile units of the cell. (wikipedia.org)
  • However, they have not changed the well-established fact that the working myocardium is mainly constituted of terminally differentiated contractile myocytes. (wikipedia.org)
  • Uterine smooth muscle has a phasic pattern, shifting between a contractile pattern and maintenance of a resting tone with discrete, intermittent contractions of varying frequency, amplitude and duration. (wikipedia.org)
  • junctional
  • The junctional layer appears to function like a circular muscle layer, capable of peristaltic and anti-peristaltic activity, equivalent to the muscular layer of the intestines. (wikipedia.org)
  • As noted for the macrostructure of uterine smooth muscle, the junctional layer appears be capable of both peristaltic and anti-peristaltic activity. (wikipedia.org)
  • Thus, wide junctional transmission has been described in many smooth muscles such as vas deferens, urinary bladder, blood vessels, gut as well as the nervous systems including ENS, autonomic ganglia and the CNS. (wikipedia.org)
  • Arteries
  • clarification needed] Most smooth muscle is of the single-unit variety, that is, either the whole muscle contracts or the whole muscle relaxes, but there is multiunit smooth muscle in the trachea, the large elastic arteries, and the iris of the eye. (wikipedia.org)
  • Single unit smooth muscle, however, is most common and lines blood vessels (except large elastic arteries), the urinary tract, and the digestive tract. (wikipedia.org)
  • iris
  • The short ciliary nerves then run forward and pierce the sclera at the back of the eye, traveling between the sclera and the choroid to innervate the iris sphincter muscle. (wikipedia.org)
  • Tone
  • A positive benefit to early breastfeeding is a stimulation of this reflex to reduce further blood loss and facilitate a swift return to prepregnancy uterine and abdominal muscle tone. (wikipedia.org)
  • structures
  • Different combinations of heavy and light chains allow for up to hundreds of different types of myosin structures, but it is unlikely that more than a few such combinations are actually used or permitted within a specific smooth muscle bed. (wikipedia.org)