• Whereas Mycobacterium tuberculosis and M. leprae are pathogenic, most mycobacteria do not cause disease unless they enter skin lesions of those with pulmonary and/or immune dysfunction, despite being widespread across aquatic and terrestrial environments. (wikipedia.org)
  • The genome sizes of mycobacteria range from relatively small ones (e.g. in M. leprae) to quite large ones, such as that as M. vulneris, encoding 6,653 proteins, larger than the ~6000 proteins of eukaryotic yeast. (wikipedia.org)
  • The development of Leprosy is caused by infection with either Mycobacterium leprae or Mycobacterium lepromatosis, two closely related bacteria. (wikipedia.org)
  • Nontuberculous mycobacteria (NTM) are mycobacteria other than M. tuberculosis (the cause of tuberculosis) and M. leprae (the cause of leprosy). (cdc.gov)
  • The bacteria, Mycobacterium leprae, ranges from 1-8 micrometres in length and 0.2-0.5 micrometres in diameter. (giantmicrobes.com)
  • In 1873 , Dr. Armauer Hansen of Norway discovered Mycobacterium leprae by looking under a microscope. (giantmicrobes.com)
  • Nontuberculous mycobacteria (NTM) refer to all mycobacteria, excluding Mycobacterium tuberculosis complex and Mycobacterium leprae . (degruyter.com)
  • Leprosy (or Hansen's disease) is a curable chronic infectious disease caused by the acid-fast bacillus Mycobacterium leprae. (rcpe.ac.uk)
  • IgG and IgM antibody levels to mycobacterial lipoarabinomannan (LAM) antigen were determined by ELISA in eight sooty mangabey monkeys (Cercocebus atys) prior to and at intervals after experimental inoculation with Mycobacterium leprae. (unboundmedicine.com)
  • Leprosy is an infectious disease caused by Mycobacterium leprae and is endemic in many developing countries. (kit.nl)
  • Contribution à l' étude du cycle végétatif de mycobacterium leprae et quelques autres mycobactéries / par Bouli Diallo. (who.int)
  • Mycobacteria are microorganisms distributed in the environment worldwide, and some of them, such as Mycobacterium tuberculosis or M. leprae, are pathogenic. (bvsalud.org)
  • Mycobacterium tuberculosis can remain latent in human hosts for decades after an initial infection, allowing it to continue infecting others. (wikipedia.org)
  • The test is performed when the doctor suspects tuberculosis or other mycobacterium infection. (medlineplus.gov)
  • This article reviews the dermatologic manifestations of Mycobacterium avium-intracellulare (MAI, or MAC) infection. (medscape.com)
  • In the United States, Mycobacterium avium-intracellulare (MAI, or MAC) infection is considered a nonreportable infectious disease. (medscape.com)
  • It is important to consider cutaneous infection with Mycobacterium avium-intracellulare (MAI, or MAC) in patients with antibiotic-resistant cellulitis, nonhealing nodules, and ulcers, as well as in patients who are immunosuppressed with evidence of disseminated MAI (DMAI) infection. (medscape.com)
  • Blood cultures should be performed in patients with symptoms, signs, or laboratory abnormalities compatible with mycobacterium infection. (cdc.gov)
  • Here, we report the case of a 22-year-old woman with renal and lymph node Mycobacterium xenopi infection. (degruyter.com)
  • We report a patient with cutaneous Mycobacterium marinum infection with a non-pruritic erythematous plaque on his right wrist for three months. (cdlib.org)
  • Mycobacterium tuberculosis, the causative agent of human tuberculosis, is forced into latency by nitric oxide produced by macrophages during infection. (ub.edu)
  • Mycobacterium chelonae--a growing problem in soft tissue infection. (medscape.com)
  • Outbreak of Mycobacterium chelonae infection associated with tattoo ink. (medscape.com)
  • Cases of coinfection included three patients with newly diagnosed pulmonary Mycobacterium infection (two cases of pulmonary TB [PTB] and one case of Mycobacterium fortuitum infection) and four patients who were already being treated for TB (three cases of PTB and one case of TB lymphadenitis). (who.int)
  • Figure 1: Three-month-old Mycobacterium ulcerans. (asm.org)
  • Three-month-old Mycobacterium ulcerans colonies growing on Middlebrook 7H10 agar supplemented with 10% oleic acid, albumin, dextrose, and catalase (OADC). (asm.org)
  • Figure 2: Three-month-old Mycobacterium ulcerans (Labeled view). (asm.org)
  • Three-month-old Mycobacterium ulcerans colonies (labeled view). (asm.org)
  • Figure 3: Five-month-old Mycobacterium ulcerans. (asm.org)
  • Five-month-old Mycobacterium ulcerans colonies growing on Middlebrook 7H10 agar supplemented with 10% OADC. (asm.org)
  • Figure 4: Five-month-old Mycobacterium ulcerans (Labeled view). (asm.org)
  • These bacteria are referred to as "atypical mycobacteria. (wikipedia.org)
  • Mycobacterium tuberculosis (MTB) and Mycobacterium avium complex (MAC) are two distinct types of bacteria that can cause infections in the lungs and other parts of the body. (medicalnewstoday.com)
  • Sputum stain for mycobacteria is a test to check for a type of bacteria that cause tuberculosis and other infections. (medlineplus.gov)
  • Seven lineages of Mycobacterium tuberculosis (MTB), the bacteria that causes "Tuberculosis" (TB), have been identified till date [ 1 ]. (hindawi.com)
  • The MBT Mycobacteria IVD software Module allows processing of more challenging mass spectra than those obtained from most other bacteria. (bruker.com)
  • M. abscessus is the most virulent rapidly-growing mycobacteria (RGM), as well as the leading cause of RGM based pulmonary infections. (wikipedia.org)
  • [ 5 ] Based on molecular diagnostics, there are 6 groups or complexes of RGM, which include the Mycobacterium chelonae-abscessus group , M fortuitum group, M smegatis group, M mageritense/M wolinskyi , M mucogenicum group, and the pigmented RGM. (medscape.com)
  • Mycobacterium abscessus Complex (MABSC) and Mycobacterium avium Complex (MAC) are now recognized as insidious opportunists that can seriously affect morbidity and mortality in CF. Fundamental paradigms of NTM pulmonary disease concerning clinical impact, patient susceptibility, transmission, bacterial modes of growth and implications for lung transplantation are currently being revised. (springer.com)
  • With ODELAM we are continuing to explore how front-line antibiotics affect growth and heterogeneity of Mtb as well as Mycobacterium abscessus . (seattlechildrens.org)
  • to species status: Mycobacterium abscessus comb. (medscape.com)
  • Nash KA, Brown-Elliott BA, Wallace RJ Jr. A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. (medscape.com)
  • Naser SA, Sagramsingh SR, Naser AS, Thanigachalam S. Mycobacterium avium subspecies paratuberculosis causes Crohn's disease in some inflammatory bowel disease patients. (wjgnet.com)
  • One theory in particular is that Mycobacterium avium subspecies paratuberculosis (MAP) is intimately linked to the etiology of CD. (wjgnet.com)
  • Does Mycobacterium avium subspecies paratuberculosis cause Crohn's disease? (bmj.com)
  • 1- 4 Interest in a possible infectious origin of this disorder was renewed in 1989 when Chiodini et al cultured apparently identical Mycobacterium avium subspecies paratuberculosis (MAP) from three patients with Crohn's disease. (bmj.com)
  • Objectives -To determine the sensitivity of bacteriologic culture of pooled fecal samples in detecting Mycobacterium paratuberculosis , compared with bacteriologic culture of individual fecal samples in dairy cattle herds. (avma.org)
  • Coenzyme A (CoA) is a fundamental co-factor for all life, involved in numerous metabolic pathways and cellular processes, and its biosynthetic pathway has raised substantial interest as a drug target against multiple pathogens including Mycobacterium tuberculosis . (nature.com)
  • The most commonly encountered mycobacterium pathogens, however, are species of MAC. (wcponline.com)
  • One very important application of this work is investigating how pathogens like Mycobacterium tuberculosis (Mtb) respond to antibiotics, as this helps inform how Mtb develops antimicrobial resistance or drug resistance. (seattlechildrens.org)
  • They are generally non-motile, except for the species Mycobacterium marinum, which has been shown to be motile within macrophages. (wikipedia.org)
  • Pasnik and Smith of the Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, produced a vaccine based on the Mycobacterium marinum Ag85A gene, and tested it on Striped bass, Morone saxatilis, a species particularly susceptible to mycobacteriosis infections. (practicalfishkeeping.co.uk)
  • 2005) - Immunogenic and protective effects of a DNA vaccine for Mycobacterium marinum in fish. (practicalfishkeeping.co.uk)
  • Mycobacterium marinum. (contemporarypediatrics.com)
  • Mycobacterium is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. (wikipedia.org)
  • While most Mycobacterium species are non-pathogenic, the genus' characteristic complex cell wall contributes to evasion from host defenses. (wikipedia.org)
  • The distinguishing characteristic of all Mycobacterium species is a thick, hydrophobic, and mycolic acid-rich cell wall made of peptidoglycan and arabinogalactan, with these unique components offering targets for new tuberculosis drugs. (wikipedia.org)
  • Many Mycobacterium species readily grow with minimal nutrients, using ammonia and/or amino acids as nitrogen sources and glycerol as a carbon source in the presence of mineral salts. (wikipedia.org)
  • Temperatures for optimal growth vary between species and media conditions, ranging from 25-45 °C. Most Mycobacterium species, including most clinically relevant species, can be cultured in blood agar. (wikipedia.org)
  • In contrast, the MAC consists of several related bacterial species, including Mycobacterium avium ( M. avium ) and Mycobacterium intracellulare ( M.intracellulare ), which are widespread in the environment. (medicalnewstoday.com)
  • Here we report that members of the family, ivermectin, selamectin, and moxidectin, are bactericidal against mycobacterial species, including multidrug-resistant and extensively drug-resistant clinical strains of Mycobacterium tuberculosis. (nih.gov)
  • Mycobacterium species retain dyes when heated and treated with acidified organic compounds. (gideononline.com)
  • There are 32 species of mycobacteria that are pathogenic to humans, including M. tuberculosis. (wcponline.com)
  • This trend and the rise of antibiotic resistance in this genus demand improved differentiation among mycobacterium species. (bruker.com)
  • The difference in antimicrobial susceptibility among different mycobacteria species makes identification down to the species level crucial for microbiology laboratories. (bruker.com)
  • Brown-Elliott BA, Wallace RJ Jr. Clinical and taxonomic status of pathogenic nonpigmented or late-pigmenting rapidly growing mycobacteria. (medscape.com)
  • rev., and elevation of Mycobacterium chelonae subsp. (medscape.com)
  • Deoxyribonucleic acid relatedness study of the Mycobacterium fortuitum-Mycobacterium chelonae complex. (medscape.com)
  • Mycobacterium fortuitum and Mycobacterium chelonae biofilm formation under high and low nutrient conditions. (medscape.com)
  • Svetlíková Z, Skovierová H, Niederweis M, Gaillard JL, McDonnell G, Jackson M. Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. (medscape.com)
  • Skin, soft tissue, and bone infections due to Mycobacterium chelonae chelonae: importance of prior corticosteroid therapy, frequency of disseminated infections, and resistance to oral antimicrobials other than clarithromycin. (medscape.com)
  • Mycobacterium chelonae infections associated with face lifts--New Jersey, 2002-2003. (medscape.com)
  • In this outbreak, a patient became infected with Mycobacterium chelonae . (medscape.com)
  • Tuberculosis (TB) is one of the major causes of death related to antimicrobial resistance worldwide because of the spread of Mycobacterium tuberculosis multi- and extensively drug resistant (multi-drug resistant (MDR) and extensively drug-resistant (XDR), respectively) clinical isolates. (frontiersin.org)
  • Clinical and laboratory aspects of the diagnosis and management of cutaneous and subcutaneous infections caused by rapidly growing mycobacteria. (medscape.com)
  • Skin and soft tissue infections due to rapidly growing mycobacteria: comparison of clinical features, treatment, and susceptibility. (medscape.com)
  • We analyzed 98 Mycobacterium tuberculosis complex platform to enhance SARS-CoV-2 testing capacity. (cdc.gov)
  • MZE0002716201 and NPV 1B53009 tion of Mycobacterium avium complex Colombia ( 1 ). (cdc.gov)
  • Sputum culture grew Mycobacterium avium complex. (medscape.com)
  • Mycobacterium avium complex (MAC) causes disseminated disease in up to 40% of patients with advanced human immunodeficiency virus (HIV) disease in the United States. (cdc.gov)
  • The U.S. Public Health Service Task Force on Prophylaxis and Therapy for Mycobacterium avium Complex was convened in Bethesda, Maryland, on December 7-8, 1992, and issued the recommendations in this report. (cdc.gov)
  • The following is a review of an opportunistic pathogen of primary concern-Mycobacterium avium complex (MAC). (wcponline.com)
  • IGRAs are endowed with great specificity, as the antigens used are almost exclusively expressed by the Mycobacterium tuberculosis (MTB) complex, but not Mycobacterium bovis bacille Calmette-Guerin (BCG) [ 1 - 3 ]. (ersjournals.com)
  • Mycobacterium avium-intracellulare complex infections are becoming an increasing concern in veterinary medicine because they affect livestock, wildlife, and companion animals. (frontiersin.org)
  • Mycobacterium avium-intracellulare complex (MAC) infections are becoming an increasing concern in veterinary medicine because they occur in a wide range of animals, including domestic animals ( 1 ), ruminant and non-ruminant wildlife ( 2 ), and companion animals ( 3 , 4 ). (frontiersin.org)
  • Tuberculosis (TB) is a deadly infectious disease caused by Mycobacterium tuberculosis that typically affects the lungs (pulmonary TB) but may also occur in other organs (extrapulmonary TB), such as the central nervous system, lymphatic system, circulatory system, genitourinary system, bones, joints, and the skin. (hindawi.com)
  • See also Mycobacterium Avium-Intracellulare . (medscape.com)
  • NTM are also referred to as atypical mycobacteria, mycobacteria other than tuberculosis (MOTT), or environmental mycobacteria. (cdc.gov)
  • Elucidating Transmission Patterns of Endemic Mycobacterium avium subsp. (mdpi.com)
  • Novel Amphiphilic Cyclobutene and Cyclobutane cis -C 18 Fatty Acid Derivatives Inhibit Mycobacterium avium subsp. (mdpi.com)
  • The government's Open Source Drug Discovery (OSDD) initiative released the results of its 'Connect 2 Decode' (C2D) project to re-annotate the biological and genetic information relating to the Mycobacterium tuberculosis ( Mtb ) genome, at a conference here on Sunday. (thehindu.com)
  • the complete genome sequence of Mycobacterium tuberculosis continues to provide an invaluable resource to understand tuberculosis (TB), the leading cause of global infectious disease mortality. (jci.org)
  • Whole-genome sequencing (WGS) of M. tuberculosis and related mycobacteria is now routine, allowing comparisons across time and space. (jci.org)
  • Mycobacterium tuberculosis (MTB) has successfully exploited macrophages as its primary niche in vivo, but the bacterial genome-wide requirements that promote its intracellular survival remain undefined. (harvard.edu)
  • According to the World Health Organization (WHO) report, in 2018, tuberculosis (TB), caused by Mycobacterium tuberculosis , was one of the major causes of death related to antimicrobial resistance ( World Health Organization [WHO], 2019a ). (frontiersin.org)
  • Mycobacteria and human disease / John M. Grange. (who.int)
  • Here we report the first structure of a full-length CoaBC, from the model organism Mycobacterium smegmatis , describe how it is organised as a dodecamer and regulated by CoA thioesters. (nature.com)
  • Mycobacterium tuberculosis is transmitted in the form of droplet nuclei exhaled by individuals affected with laryngeal/pulmonary TB. (gideononline.com)
  • Through biofilm formation, cell wall resistance to chlorine, and association with amoebas, mycobacteria can survive a variety of environmental stressors. (wikipedia.org)
  • Amoebal coculture of "Mycobacterium massiliense" sp. (medscape.com)
  • The MBT compares the mass spectrum of an unknown organism with the dedicated library of reference mass spectra, which covers 182 of the currently known 201 mycobacteria. (bruker.com)
  • Cite this: Mycobacteria Infections Associated With Tattooing - Medscape - Sep 27, 2012. (medscape.com)
  • The recent emergence of advanced mass spectrometry (MS) technology, specifically Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight (MALDI-TOF) MS, enables clinical microbiology laboratories to master the challenge of mycobacteria identification. (bruker.com)
  • Mycobacterium tuberculosis (MTb) has long been a likely contender as the inciting antigen in sarcoidosis, although Koch's postulates have never been fulfilled. (bmj.com)
  • Ebani VV, Fratini F, Bertelloni F, Cerri D, Tortoli E. Isolation and identification of mycobacteria from captive reptiles. (medscape.com)
  • Mycobacterium tuberculosis belonging to Beijing sublineage (BL) is associated with high tuberculosis (TB) transmission, multidrug resistance, and adverse treatment outcomes. (hindawi.com)
  • Mycobacteria possess capsules and most do not form endospores. (wikipedia.org)
  • Mycobacteria possess specialized protein secretion systems , such as the Early Secretory Antigenic Target 6 secretion (ESX) system. (bvsalud.org)
  • The transmission of Mycobacterium tuberculosis that we describe aboard a commercial aircraft involved a highly infectious passenger, a long flight, and close proximity of contacts to the index patient. (nih.gov)
  • Is International Travel an Emerging Issue on Transmission of Beijing Lineage Mycobacterium tuberculosis? (hindawi.com)
  • Adékambi T, Berger P, Raoult D, Drancourt M. rpoB gene sequence-based characterization of emerging non-tuberculous mycobacteria with descriptions of Mycobacterium bolletii sp. (medscape.com)
  • The agar media used for most water testing does not support the growth of mycobacteria, allowing it to go undetected in municipal and hospital systems. (wikipedia.org)
  • [ 5 ] This resulted in NTM being broadly categorized into rapid growing mycobacteria (RGM) or slow growing mycobacteria (SGM), based on the presence of growth on solid media either occuring within 7 days, or after 7 days, respectively. (medscape.com)
  • This MBT Mycobacteria IVD Library can conveniently be applied for samples independently from growth on liquid or solid medium. (bruker.com)
  • Kusunoki S, Ezaki T. Proposal of Mycobacterium peregrinum sp. (medscape.com)
  • Results of search for 'su:{Mycobacterium. (who.int)
  • Samples flagged as mycobacteria will undergo an optimized acquisition method and spectra are automatically compared to the MBT Mycobacteria IVD Library, for sensitive and specific identification. (bruker.com)