What cellular mechanisms govern early morphogenesis of epithelial appendages? (helsinki.fi)
catenin is important for epithelial pseudostratification and the establishment of a region of double-positive cells at the dorso-ventral midline through close examination of epithelial morphogenesis at E10.5 prior to compartmentalization. (duke.edu)
Taken together, our results show that modulation of stromal paracrine signaling and ECM remodeling by SPRY1 regulates mammary epithelial morphogenesis during postnatal development. (muni.cz)
These results highlight the importance of the concerted action of extracellular syntaxin4 extruded in response to the lactogenic hormone and BM components in epithelial morphogenesis. (datadryad.org)
The goal of the project is to develop new strategies for the synthetic morphogenesis of epithelial tissues. (ibecbarcelona.eu)
Craniofacial3
Collectively, these models provide a range of experimental approaches to investigate the molecular and cellular mechanisms directing the morphogenesis of the craniofacial tissues and associated organs in health and disease. (grc.org)
Invited presentations by leading researchers and clinician scientists in the field will present new findings in craniofacial morphogenesis and regeneration, with specific focus on the role that mechanics plays in shaping development. (grc.org)
This GRC will be held in conjunction with the "Craniofacial Morphogenesis and Tissue Regeneration" Gordon Research Seminar (GRS). (grc.org)
Neuronal morphogenesis1
Together, our data support a model in which the V409I/A mutations disrupt microtubule regulation typically conferred by XMAP215 proteins during neuronal morphogenesis and migration, and this impact on tubulin activity at the molecular level scales with the impact at the cellular and tissue levels. (elifesciences.org)
Pathways2
Developmental signaling pathways implicated in morphogenesis include Wnt, Hedgehog, and ephrins. (wikipedia.org)
What molecular pathways govern mammary branching morphogenesis? (helsinki.fi)
Drosophila1
By correlating dynamic patterns of transcription factor expression with rigorous, quantitative analyses of cell behaviors across the salivary gland primordium in Drosophila , their results suggest Hkb and Fkh transcription factor patterning induces switches in cell behaviors at fixed positions to promote continued morphogenesis of the tubular structure. (elifesciences.org)
Mammary2
Here, we show that sprouty 1 (SPRY1) modulates the microenvironment to enable proper mammary branching morphogenesis. (muni.cz)
Mammary epithelia undergo dramatic morphogenesis after puberty. (datadryad.org)
Proteins1
An important class of molecules involved in morphogenesis are transcription factor proteins that determine the fate of cells by interacting with DNA. (wikipedia.org)
Biological2
Morphogenesis (from the Greek morphê shape and genesis creation, literally "the generation of form") is the biological process that causes a cell, tissue or organism to develop its shape. (wikipedia.org)
Some of the earliest ideas and mathematical descriptions on how physical processes and constraints affect biological growth, and hence natural patterns such as the spirals of phyllotaxis, were written by D'Arcy Wentworth Thompson in his 1917 book On Growth and Form and Alan Turing in his The Chemical Basis of Morphogenesis (1952). (wikipedia.org)
Neurons1
We show that short hairpin RNA-mediated knockdown of erbin and knockdown or genetic ablation of δ-catenin severely impaired dendritic morphogenesis in hippocampal neurons. (jneurosci.org)
Mesoderm1
In many well-studied cases of tissue morphogenesis, such as mesoderm invagination or germband extension in the fly, many morphogenetic effectors are induced evenly across the tissue primordium. (elifesciences.org)
Tissue4
Morphogenesis can take place also in a mature organism, such as in the normal maintenance of tissue by stem cells or in regeneration of tissues after damage. (wikipedia.org)
Cancer is an example of highly abnormal and pathological tissue morphogenesis. (wikipedia.org)
At a tissue level, ignoring the means of control, morphogenesis arises because of cellular proliferation and motility. (wikipedia.org)
Our work aims at providing insights into (1) the interplay between the dynamic organization of cytoskeletal filaments and cell shape changes, and (2) the reciprocal links between tissue growth, morphogenesis and tissue mechanics. (fresnel.fr)
Abnormal1
Abnormal morphogenesis is called dysmorphogenesis. (wikipedia.org)
20221
Suddenly 2022 is upon us and things seem to be moving in a better direction and the promo kit for Morphogenesis hits my in box, and, wait for it, wait. (brutalresonance.com)
Patterning2
Morphogenesis is a mechanical process involving forces that generate mechanical stress, strain, and movement of cells, and can be induced by genetic programs according to the spatial patterning of cells within tissues. (wikipedia.org)
Precise spatial patterning of cell fate during morphogenesis requires accurate inference of cellular position. (ncbs.res.in)
Tissues3
Morphogenesis also involves changes in the cellular structure or how cells interact in tissues. (wikipedia.org)
During embryonic morphogenesis, the myosin II motor protein generates forces that help to shape tissues, organs, and the overall body form. (aps.org)
Our work with pollywog ( pwg ) maternal-effect mutants highlights the delicate control of the YSL during yolk morphogenesis, and provides novel insight into understanding which tissues of the embryo are affected by loss of a cohesive YSL. (rice.edu)
Inference1
Cellular compartmentalisation and receptor promiscuity as a strategy for accurate and robust inference of position during morphogenesis. (ncbs.res.in)
Cell5
In plants, cellular morphogenesis is tightly linked to the chemical composition and the mechanical properties of the cell wall. (wikipedia.org)
This volume is concerned with the individual steps in the pathway of retrovirus morphogenesis and maturation starting at the point where the components of the virion have been synthesized within the infected cell and ending once the infectious virion has been released from this cell. (powells.com)
The individual chapters of the book deal with specific steps in the pathway of retroviral morphogenesis and maturation, starting at the time when the components of the virus have been synthesized within the infected cell and ending once the infectious virion has been released from the cell. (powells.com)
Morphogenesis is preparing to initiate a single randomized placebo-controlled Phase 2/3 registration trial of IFx-Hu2.0 administered as an adjunct to Keytruda ® (pembrolizumab) in first line treatment for metastatic Merkel Cell Carcinoma (MCC). (tmcnet.com)
This coupling of gene expression to morphogenesis is achieved by exporting the flagellum-specific anti-sigma factor, FlgM, out of the cell through the mature hook-basal body structure. (unboundmedicine.com)
Mechanisms1
The possible macromolecular mechanisms that may be involved in the submicroscopic morphogenesis of the rod sacs are discussed and the possible role of the morphogenetic material is considered. (rupress.org)
Methods1
The architects of Morphogenesis apply local building methods to create a contemporary production facility, creating job opportunities in harmony with the local traditions and environment, a source of great pride for the population. (floornature.com)
Mice2
In teleosts, the Yolk Syncytial Layer (YSL) is functionally similar to the anterior visceral endoderm found in mice and is required for morphogenesis of the overlying blastoderm. (rice.edu)
The morphogenesis of the retinal rods has been studied with the electron microscope in white mice from birth up to the 16th day of age. (rupress.org)
Evolution1
Morphogenesis is essential for the evolution of new forms. (wikipedia.org)
Close1
The Morphogenesis project also maintains the large aangans , gathering spaces, to support the close-knit local community . (floornature.com)
Development2
Morphogenesis also describes the development of unicellular life forms that do not have an embryonic stage in their life cycle. (wikipedia.org)
Where Thompson explained animal body shapes as being created by varying rates of growth in different directions, for instance to create the spiral shell of a snail, Turing correctly predicted a mechanism of morphogenesis, the diffusion of two different chemical signals, one activating and one deactivating growth, to set up patterns of development, decades before the formation of such patterns was observed. (wikipedia.org)
Cells1
In this work , studies using transmission and scanning electron microscopy and 3D electron microscopy modeling were performed with the goal of characterizing the morphogenesis of SARS-CoV-2 in Vero-E6 cells . (bvsalud.org)
Process1
Metropolis Records took interest in Paradox Obscur and released the CD/LP version of Morphogenesis and previously the Singles & Rarities CD giving the US market a chance to easily pick this up in your favorite music store or order domestically given the shipping can be a long, unpredictable and expensive process any time crossing oceans are involved following a global pandemic. (brutalresonance.com)
Essential1
Among six classes of Kinesin-14 motors in Arabidopsis thaliana, the Kinesin-14A motors ATK1 (KatA) and ATK5 share the essential function in spindle morphogenesis. (figshare.com)
Atlas of human prenatal morphogenesis / Jan E. Jir'asek, with the technical assistance of B. Faltinov'a and L. R. Sweney. (who.int)
Specific1
LEKTI is involved in skin disorder or hairmorphogenesis and has also a specific role in thymus. (lu.se)
Proper1
Our data describes an early and novel role for Map3k4, p38a and Mxtxl activity that is required for proper morphogenesis of the YSL and the blastoderm. (rice.edu)
Form1
Morphogenesis and CohBar recently announced that they have entered into a definitive merger agreement for an all-stock transaction to form a company combining expertise and resources to advance a late-stage oncology pipeline. (tmcnet.com)
Article1
Is the Subject Area "Morphogenesis" applicable to this article? (plos.org)
Place1
If you slept on Paradox Obscur for a while, Morphogenesis is a great place to rekindle the relationship. (brutalresonance.com)
Shape1
Orchestrating size and shape during morphogenesis. (fresnel.fr)
Focus1
The combined company will focus on advancing Morphogenesis' two technologies that seek to overcome the major obstacles that limit the effectiveness of current immunotherapies in treating cancer. (tmcnet.com)
Plants1
Keeping nodules in check: Interplay of rhizobial and host factors controlling nodule morphogenesis and identity in legume plants. (europa.eu)