• MAPKs
  • MAPKs are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. (wikipedia.org)
  • P38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell differentiation, apoptosis and autophagy. (wikipedia.org)
  • animals
  • While animals produce internal signals that can drive the cell cycle forward, external mitogens can cause it to progress without these signals. (wikipedia.org)
  • effects
  • This is not true for all growth factors, as some growth factors instead appear to cause mitogenic effects like growth indirectly by triggering other mitogens to be released, as evidenced by their lack of mitogenic activity in vitro, which VEGF has. (wikipedia.org)
  • Mitogens are important in cancer research due to their effects on the cell cycle. (wikipedia.org)
  • medicine
  • The most commonly used mitogens in clinical laboratory medicine are: Lipopolysaccharide toxin from gram-negative bacteria is thymus-independent. (wikipedia.org)