• Productive Performance and Urinary Excretion of Mimosine Metabolites by Hair Sheep Grazing in a Silvopastoral System with High Densities of Leucaena Leucocephala. (edu.mx)
  • Leucaena contains a toxic, nonprotein amino acid, mimosine, which is also formed by an OAS-TL, and characterization of this enzyme is essential for developing a mimosine-free leucaena for its use as a protein-rich fodder. (unipr.it)
  • Then, the binding mode and self-assembly features of the peptides were evaluated using a DFT approach, taking into account different number of mimosine amino acids and varying the length of the spacer between the mimosine residues, and there was good agreement between experimental data and computational calculations. (edu.sa)
  • Reagents for peptide synthesis which contain unusual amino acids mimosine. (hipep.com)
  • Due to its structural similarity with deferiprone (DFP), mimosine is a potential excellent metal chelator. (edu.sa)
  • The metalloenzyme DOHH has been targeted by iron-chelating compounds, such as mimosine and deferiprone ( 25 ). (jci.org)
  • Mimosine or leucenol is a toxic non-protein amino acid chemically similar to tyrosine. (wikipedia.org)
  • It is demonstrated for the first time that mimosine, a naturally occuring toxic amino acid, could be a beneficial growth factor in concentrations between 0.1 and 0.2 mM. (typeset.io)
  • Mimosine, a toxic amino acid, was also found to be beneficial to the growth of the seedlings exposed up to 0.2 mM. (typeset.io)
  • Mimosa pudica contains the toxic alkaloid mimosine, which has been found to also have antiproliferative and apoptotic effects. (luminescents.net)
  • Livestock feed should not contain more than 20% of L. leucocephala, as the mimosine can cause hair loss and stomach problems. (unitedcaribbean.com)
  • 175-6 °C.[citation needed] Mimosine arrests dividing cells in the late G1 phase by inhibiting DNA replication initiation. (wikipedia.org)
  • For the determination of testosterone and mimosine in blood, an ELISA kit and HPLC were used respectively. (edu.mx)
  • In the present study, we used a reversible cell cycle inhibitor, mimosine, to synchronize porcine granulosa cells (GCs) in G1 phase of the cell cycle. (bvsalud.org)
  • A) HeLa cells were arrested in the G1/S transition with Mimosine (T1), released into S phase and harvested every 2 hrs for 8 hrs (T2CT5). (irjs.info)
  • Besides, Moe Thida Htun, from Myanmar also found another new sub-species of Baccilus aureus that can degrade mimosine. (wikipedia.org)
  • The soluble activity in mimosine groups increased twofold, but only by 75% in Se groups. (typeset.io)
  • Peroxidase activity registered a significant increase by threefold in mitochondria and fourfold in soluble fraction in both Se and mimosine groups. (typeset.io)
  • In the Se groups, both catalase and Asc-Px in mitochondria decreased by 50-60%, which was contrasted by 60% increase in Asc-Px activity and 40% in catalase activity in mimosine groups. (typeset.io)
  • Further elucidations of the structural properties of these peptides allowed us to propose improvements in the structure of the mimosine moiety which can lead to enhanced affinity for high-valent metals. (edu.sa)
  • The results of the present study reveal (1) the Prevalence of oxidative stress inT. foenum-graecum during Se deficiency, (2) enhanced mitochondrial functional efficiency mediated by Se and mimosine independently, and (3) an antitoxidative role for mimosine during Se deficiency. (typeset.io)
  • Tolerance might be related to the presence or absence of microbes tolerant to mimosine and 3,4-DHP. (wikipedia.org)
  • There is a presence of the alkaloid, mimosine. (theayurveda.org)
  • The N-terminal affinity His-tag was cleaved from the recombinant OAS-TL to eliminate its possible interference in binding with the substrate, 3-hydroxy-4-pyridone, for mimosine formation. (unipr.it)
  • The His-tag-cleaved OAS-TL was again observed to catalyze the formation of cysteine but not mimosine. (unipr.it)
  • In the present work, we combine experimental and theoretical (DFT) approaches in order to investigate the properties of mimosine peptides. (edu.sa)
  • In summary, in the present work, we propose a new generation of multipurpose mimosine-based peptides as new metal self-assembly chelators which could be a turning point in biomedical and nanotechnological applications. (edu.sa)
  • Mimosine or leucenol is a toxic non-protein amino acid chemically similar to tyrosine. (wikipedia.org)
  • The purified protein product showed a dual function of cysteine and mimosine synthesis. (unipr.it)
  • Kinetics studies showed pH optima of 7.5 and 8.0, while temperature optima of 40 and 35 C, respectively, for cysteine and mimosine synthesis. (unipr.it)
  • The kinetic parameters such as apparent Km, kcat were determined for both cysteine and mimosine synthesis with substrates O-acetylserine (OAS) and Na2S or 3-hydroxy-4-pyridone (3H4P). (unipr.it)
  • The mimosine content, crude protein and crude fiber were decreased with the increasing of EMS doses. (unimas.my)
  • Even though this plant has a lot of uses and nutrition properties, it's also home for a strong toxic protein called mimosine that causes alopecia, growth retardation, cataract, etc. (maya-ethnobotany.org)
  • An additional group of RK rats was treated with L-mimosine to study the effect of HIF-α activation. (trpv-antagonist.com)
  • The cell population with the nucleolar distribution is enriched upon treatment with mimosine, a synchronizing drug in late G(1) phase. (nih.gov)
  • Furthermore, fibrosis markers α-smooth muscle actin (α-SMA) and Collagen III, as well as peritubular capillary rarefaction index, were all significantly decreased after L-mimosine treatment. (trpv-antagonist.com)
  • L-mimosine administered from week 5 to week 12 led to accumulation of HIF-1α and HIF-2α proteins, increased expression of VEGF, HO-1 and GLUT-1, and improved renal function. (trpv-antagonist.com)
  • 19. L-mimosine and dimethyloxaloylglycine decrease plasminogen activation in periodontal fibroblasts. (nih.gov)