• dense
  • Each microvillus has a dense bundle of cross-linked actin filaments, which serves as its structural core. (wikipedia.org)
  • The cross-section of each microvillus (in blue) is bounded by two dense lines of similar thickness (in black) separated by a lighter intermediate zone (in pink). (sciencephoto.com)
  • When the cells were grown in dense colonies, they were found on top of each other, and microvilli were present on all sides, except on the bottom surface of those cells in contact with the dish. (rupress.org)
  • absorb
  • In the nose, olfactory receptor cells covered with microvilli absorb minute amounts of scent-laden moisture and transmit the information to the brain. (wisegeek.com)
  • In the intestines, microvilli increase the surface area of digestive cells to help the intestines absorb every bit of nutrition gleaned from ingested food. (wisegeek.com)
  • proteins
  • 20 to 30 tightly bundled actin filaments are cross-linked by bundling proteins fimbrin (or plastin-1), villin and espin to form the core of the microvilli. (wikipedia.org)
  • The plus ends of the actin filaments are located at the tip of the microvillus and are capped, possibly by capZ proteins, while the minus ends are anchored in the terminal web composed of a complicated set of proteins including spectrin and myosin II. (wikipedia.org)
  • The microvilli are covered with glycocalyx, consisting of peripheral glycoproteins that can attach themselves to a plasma membrane via transmembrane proteins. (wikipedia.org)
  • Numerous components, including ezrin/radixin/moesin (ERM) proteins, have been identified that link filamentous actins to transmembrane proteins, but the signals driving microvillus biogenesis are not known. (rupress.org)
  • The proteins and serosal fluid trapped by the microvilli provide a slippery surface for internal organs to slide past one another. (wikipedia.org)
  • myosin
  • In the enterocyte microvillus, the structural core is attached to the plasma membrane along its length by lateral arms made of myosin 1a and Ca2+ binding protein calmodulin. (wikipedia.org)
  • proximal
  • Microvilli appear in the proximal tubule of the kidney as a "brush border," so-called because this close clustering of tiny outpocketings resemble the tip of a paintbrush under a light microscope. (wisegeek.com)
  • molecular
  • In one patient with late-onset microvillus atrophy, the molecular defect involved a different protein, supposedly identified as vinculin. (medscape.com)
  • present
  • It revealed that, although the microvilli were present on all sides of the cell in the dispersed stage and in the attached stage, they were not present on the bottom of the cell when it was stretched on the surface of the dish. (rupress.org)
  • Desmosomes and microvilli are present. (wikipedia.org)
  • Microvilli are present in the canaliculi but are sparse. (wikipedia.org)
  • small
  • For example, the microvilli in the small and large intestines in mice are slightly different in length and amount of surface coat covering. (wikipedia.org)
  • composition
  • Though the length and composition of microvilli is consistent within a certain group of homogenous cells, it can differ slightly in a different part of the same organism. (wikipedia.org)
  • cells
  • Each of these cells has many microvilli. (wikipedia.org)
  • Microvilli are observed on the plasma surface of eggs, aiding in the anchoring of sperm cells that have penetrated the extracellular coat of egg cells. (wikipedia.org)
  • Microvilli are also of importance on the cell surface of white blood cells, as they aid in the migration of white blood cells. (wikipedia.org)
  • The destruction of microvilli can occur in certain diseases because of the rearrangement of cytoskeleton in host cells. (wikipedia.org)
  • The destruction of microvilli can actually be beneficial sometimes, as in the case of elimination of microvilli on white blood cells which can be used to combat auto immune diseases. (wikipedia.org)
  • The microvilli likely aid in localization of foreign debris (coming from the nose) and detection by immune cells. (sciencephoto.com)
  • protein
  • Using super-resolution microscopy and live cell imaging, Matthew Tyska , PhD, and colleagues show that a protein called insulin receptor tyrosine kinase substrate (IRTKS) promotes microvilli elongation. (vumc.org)