• nausea
  • Metoclopramide is commonly used to treat nausea and vomiting associated with conditions such as uremia, radiation sickness, cancer and the effects of chemotherapy, labor, infection, and emetogenic drugs. (wikipedia.org)
  • Dopamine produces nausea and vomiting by stimulation of the medullary chemoreceptor trigger zone (CTZ), and metoclopramide blocks stimulation of the CTZ by agents like l-dopa or apomorphine which are known to increase dopamine levels or to possess dopamine-like effects. (nih.gov)
  • The injectable form of metoclopramide is most often used for the prevention of nausea and vomiting caused by chemotherapy. (medbroadcast.com)
  • Furthermore, anti-nausea drugs, such as metoclopramide, which do cross the blood-brain barrier may worsen the extra-pyramidal symptoms of Parkinson's disease. (wikipedia.org)
  • injection
  • Metoclopramide Injection 5mg/mL Prefilled Syringe by BD Rx Inc. (empr.com)
  • BD announced the launch of Metoclopramide Injection, the second drug to be offered in the BD Simplist ready-to-administer line of prefilled generic injectables. (empr.com)
  • Metoclopramide Injection will be available as a 5mg/mL strength in a 2mL prefilled single-use syringe in a 24-count carton. (empr.com)
  • elderly
  • Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of metoclopramide in the elderly. (drugs.com)
  • effects
  • Metoclopramide inhibits the central and peripheral effects of apomorphine, induces release of prolactin and causes a transient increase in circulating aldosterone levels, which may be associated with transient fluid retention. (nih.gov)
  • Although experience with the effects of metoclopramide on esophageal erosions and ulcerations is limited, healing was documented in a controlled trial using four times daily therapy at 15 mg/dose. (drugs.com)