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  • allergic
  • Tell your doctor if you have ever had any unusual or allergic reaction to metoclopramide or any other medicines. (drugs.com)
  • You should not take this medication if you are allergic to metoclopramide, or if you have bleeding or blockage in your stomach or intestines, epilepsy or other seizure disorder, or an adrenal gland tumor (pheochromocytoma). (wellspan.org)
  • oral
  • Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects. (nih.gov)
  • Metoclopramide Oral Solution, USP is a clear, butterscotch flavor, sugar-free liquid for oral administration. (nih.gov)
  • nausea
  • Dopamine produces nausea and vomiting by stimulation of the medullary chemoreceptor trigger zone (CTZ), and metoclopramide blocks stimulation of the CTZ by agents like l-dopa or apomorphine which are known to increase dopamine levels or to possess dopamine-like effects. (nih.gov)
  • The injectable form of metoclopramide is most often used for the prevention of nausea and vomiting caused by chemotherapy. (medbroadcast.com)
  • drugs
  • The effect of metoclopramide on motility is not dependent on intact vagal innervation, but it can be abolished by anticholinergic drugs. (nih.gov)
  • elderly
  • Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of metoclopramide in the elderly. (drugs.com)
  • effects
  • Metoclopramide inhibits the central and peripheral effects of apomorphine, induces release of prolactin and causes a transient increase in circulating aldosterone levels, which may be associated with transient fluid retention. (nih.gov)
  • Although experience with the effects of metoclopramide on esophageal erosions and ulcerations is limited, healing was documented in a controlled trial using four times daily therapy at 15 mg/dose. (drugs.com)