• enzymology
  • In enzymology, a hexaprenyldihydroxybenzoate methyltransferase (EC 2.1.1.114) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate Thus, the two substrates of this enzyme are S-adenosyl methionine and 3-hexaprenyl-4,5-dihydroxybenzoate, whereas its two products are S-adenosylhomocysteine and 3-hexaprenyl-4-hydroxy-5-methoxybenzoate. (wikipedia.org)
  • In enzymology, an amine N-methyltransferase (EC 2.1.1.49) is an enzyme that is ubiquitously present in non-neural tissues and that catalyzes the N-methylation of tryptamine and structurally related compounds. (wikipedia.org)
  • In enzymology, a phenol O-methyltransferase (EC 2.1.1.25) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + phenol ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + anisole Thus, the two substrates of this enzyme are S-adenosyl methionine and phenol, whereas its two products are S-adenosylhomocysteine and anisole. (wikipedia.org)
  • In enzymology, a polysaccharide O-methyltransferase (EC 2.1.1.18) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + 1,4-alpha-D-glucooligosaccharide ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units Thus, the two substrates of this enzyme are S-adenosyl methionine and 1,4-alpha-D-glucooligosaccharide, whereas its two products are S-adenosylhomocysteine and oligosaccharide containing 6-methyl-D-glucose units. (wikipedia.org)
  • liver
  • Phosphatidylethanolamine N-methyltransferase (abbreviated PEMT) is a transferase enzyme (EC 2.1.1.17) which converts phosphatidylethanolamine (PE) to phosphatidylcholine (PC) in the liver. (wikipedia.org)
  • structures
  • The thirteen chapters describe in detail the structures, enzyme kinetics and biological roles of the AdoMet-dependent methyltransferases from a wide range of cell types: plant, animal, bacterial and archaeal. (google.com)
  • Catalytic
  • The structure of HhaI methyltransferase (M.HhaI) has been resolved to 2.5 A: the molecule folds into 2 domains - a larger catalytic domain containing catalytic and cofactor binding sites, and a smaller DNA recognition domain. (wikipedia.org)
  • Universal catalytic domain structure of AdoMet-dependent methyltransferases. (ebi.ac.uk)
  • found primarily
  • MTases can be divided into three different groups on the basis of the chemical reactions they catalyze: m6A - those that generate N6-methyladenine EC 2.1.1.72 m4C - those that generate N4-methylcytosine EC 2.1.1.113 m5C - those that generate C5-methylcytosine EC 2.1.1.37 m6A and m4C methyltransferases are found primarily in prokaryotes. (wikipedia.org)