Mediastinal diseases. Medical search. Frequent questions

When Do Symptoms of Mediastinal endodermal sinus tumors Begin? (nih.gov)
D. C. Strollo, M. L. Rosado-de-Christenson, and J. R. Jett, "Primary mediastinal tumors-part II: tumors of the middle and posterior mediastinum," Chest , vol. 112, no. 5, pp. 1344-1357, 1997. (hindawi.com)
Mediastinal tumors/lesions are frequently encountered in daily cytopathology practice. (allenpress.com)
Tumors metastatic to mediastinal lymph nodes represent the most common mediastinal lesions and must be differentiated from primary lesions. (allenpress.com)
To provide an updated review on the fine-needle aspiration cytology of mediastinal tumors/lesions, with an emphasis on diagnostic challenges. (allenpress.com)
Data were gathered from a PubMed search of peer-reviewed literature on mediastinal tumors. (allenpress.com)
1 The most frequent primary tumor types of anterior mediastinal masses are thymic tumors and lymphoma, with approximate proportions of 35% and 25% among mediastinal lesions, respectively. (allenpress.com)
Available at: https://www.ctsnet.org/article/surgical-management-primary-mediastinal-germ-cell-tumors. (epnet.com)
Available at: https://www.brighamandwomens.org/lung-center/diseases-and-conditions/germ-cell-tumors. (epnet.com)

This enables direct visualization of the mediastinal structures and allows us to obtain tissue samples from the lymph nodes and other areas within the mediastinum. (schmetterermd.com)
A computed tomography scan ( Figure 1 , panel B) confirmed the mass to be a 7-cm × 6-cm loculated fluid collection in the anterior mediastinum contiguous with patchy bilateral pneumonia and associated with multiple enlarged mediastinal lymph nodes and a pericardial effusion. (cdc.gov)
Cervical mediastinoscopy is the "gold standard" for mediastinal staging but is invasive and limited in assessing the posterior subcarinal, lower mediastinal, and hilar lymph nodes. (medpagetoday.com)
Without my even asking, he gave me a preliminary diagnosis of sarcoid (inflammatory disease) or small cell lung cancer, due to the fact my lymph nodes were not like this on my June scan. (cancer.org)
Prognosticating Outcomes in Interstitial Lung Disease by Mediastinal Lymph Node Assessment. (bvsalud.org)
Approximately one third of patients have enlarged hilar or mediastinal lymph nodes. (cdc.gov)
Among other findings, following inhalation exposure to Indium-tin Oxide (ITO) animal studies have revealed hyperplasia of mediastinal lymph nodes and granulomas of mediastinal nodes and bronchus-associated lymphoid tissue. (cdc.gov)
This study aims to introduce an optimized method named "non-grasping en bloc mediastinal lymph node dissection (MLND)" through video-assisted thoracoscopic surgery (VATS). (medscape.com)

The staging of these patients starts with radiographic imaging -- typically with integrated PET/CT -- and in most cases, in the absence of distant metastatic disease, mediastinal staging is often critical for determining surgical candidacy. (medpagetoday.com)
Metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic disease. (drugs.com)
This could be due to primary lung neoplasm, inflammatory process such as sarcoidosis, lymphoma, or metastatic disease. (cancer.org)
Metastatic disease occurs in 16% of all RMS cases and has a poor prognosis. (bvsalud.org)

Invited Commentary: New Paradigm for Imaging Evaluation of Pediatric Mediastinal Masses-ITMIG Classification System. (harvard.edu)
Mediastinal Masses (Merck & Co., Inc. (medlineplus.gov)
Most mediastinal masses seen on thoracic imaging are of solid tumor origin. (nih.gov)
As such, vascular lesions of the mediastinum can be mistaken for, or misinterpreted as, one of these more common mediastinal masses. (nih.gov)
This article stresses the importance of considering vascular entities in the differential diagnosis of mediastinal masses. (nih.gov)
Transbronchial needle aspiration (TBNA) is a safe and useful sampling technique for the diagnosis of mediastinal adenopathies/masses, but its accuracy seems to be influenced by selected clinical and procedural aspects. (karger.com)
The role of transbronchial needle aspiration (TBNA) for the diagnosis of mediastinal adenopathies/masses, as well as for lung cancer staging, is well established. (karger.com)
Purpose: Anesthesia and airway management for mediastinal masses are challenging and are accompanied by mortality and morbidity. (scirp.org)
Avoiding the loss of airway muscular tone in mediastinal masses has been confirmed necessary to avoid airway collapse. (scirp.org)
Conclusion: Owing to the characteristics of the "subcutaneous dissociative conscious sedation" this method is suggested as an appropriate substitute to general anesthesia for Endobronchial Double Lumen Intubation in mediastinal masses and compromised airway. (scirp.org)
M. Javid, M. Rahim and S. Rafiian, "Subcutaneous Dissociative Conscious Sedation (sDCS) a New Approach to Compromised Airway in Mediastinal Masses," Open Journal of Anesthesiology , Vol. 2 No. 4, 2012, pp. 166-169. (scirp.org)
The lymphoblasts infiltrate nodal structures or extranodal structures and is commonly associated with large mediastinal masses with a high predilection for disseminating to bone marrow and the central nervous system (CNS). (medscape.com)

The radiologist's impression reads "interval development of extensive hyper metabolic and pathologically enlarged hilar/mediastinal adenopathy. (cancer.org)

Transbronchial needle aspiration combined with cryobiopsy in the diagnosis of mediastinal diseases: a multicentre, open-label, randomised trial. (nih.gov)
Extramedullary disease is typically an aggressive, poorly differentiated form of MM that confers inferior outcome, with median survival of less than 1 y if present at diagnosis. (snmjournals.org)
He suffered recurrent pulmonary infections and succumbed to severe pneumonia with respiratory failure and pulmonary hypertension five years after the diagnosis of malignant lymphoma without evidence of recurrence of Hodgkin's disease. (hindawi.com)
Utilizing the latest in minimally invasive surgical techniques, sometimes known as "camera" surgery, our integrated teams include doctors trained in diagnosis, surgery, pathology (disease) and oncology (cancer). (swedish.org)
9-14 However, the reports to date have not always provided clear clinical evidence supporting the diagnosis of sarcoidosis nor have they excluded patients with prior tuberculous disease or infection. (bmj.com)
Because the early signs are non-specific, it is important to consider the diagnosis early in any patient with known TB exposure, infection, or disease, including past TB, and in all persons with compatible symptoms from high TB-burden locations. (msdmanuals.com)
identify other tests that can assist with diagnosis of beryllium-related diseases. (cdc.gov)

Overview of Interstitial Lung Disease Interstitial lung diseases are a heterogeneous group of disorders characterized by alveolar septal thickening, fibroblast proliferation, collagen deposition, and, if the process remains unchecked. (merckmanuals.com)
Idiopathic interstitial pneumonia should be suspected in any patient with unexplained interstitial lung disease. (merckmanuals.com)
Rarely, there has also been evidence of interstitial lung disease, such as sarcoidosis, pulmonary fibrosis, and bronchiolitis obliterans. (cdc.gov)

A 31-Year-Old Man With Fever, Atypical Chest Pain, and Mediastinal Mass. Chest. (harvard.edu)
People with lung, esophagus or chest disease who entrust their care to Virtua receive expert treatment from board-certified and fellowship-trained thoracic surgeons who specialize in minimally invasive procedures. (virtua.org)
This includes radiation to the chest or thorax (including mantle, mediastinal and/or axillary treatments fileds), abdomen, spine or total body irradiation (TBI). (medscape.com)
The chest radiograph is usually normal in early disease. (cdc.gov)
Chest X-ray showed mediastinal lymphadenitis and consolidation on the right lung. (who.int)

It provides assessment of the potential etiology, extent, and distribution of disease and is more likely to detect underlying or coexisting disease (eg, occult mediastinal adenopathy, cancer, emphysema). (merckmanuals.com)
Pulmonary disease including pulmonary fibrosis, emphysema and pulmonary alveolar proteinosis has been observed in workers in the indium industry. (cdc.gov)

It is typically employed when there is a suspicion of certain diseases or conditions, such as lung cancer, lymphoma, infections, or inflammatory disorders, affecting the structures in this region. (schmetterermd.com)
Intracellular bacteria in Hodgkin s disease and sclerosing mediastinal B-cell lymphoma: sign of a bacterial etiology? (smw.ch)
Despite significant improvements in the treatment of Hodgkin's lymphoma over the past 2 decades, physicians continue to face dilemmas in therapy for the disease, and many cured patients live with complications of treatment. (cancernetwork.com)
This review considers the treatment of Hodgkin's lymphoma in younger patients, addressing such issues as which patients with early-stage disease may require radiotherapy, what prognostic factors provide information that can affect treatment choices in patients with advanced disease, and what we have learned about treatment complications in this setting. (cancernetwork.com)
Hodgkin's lymphoma (HL) is a rare, curable malignancy, and investigators have made remarkable improvements in treatment of the disease over the past 20 years. (cancernetwork.com)
Treatment protocols for classical Hodgkin lymphoma (HL) are provided below, including treatment for early-stage, advanced-stage, and relapsed/refractory disease. (medscape.com)
however, because lymphoblastic lymphoma and acute lymphoblastic leukemia (ALL) are known to represent the same disease entity, the World Health Organization (WHO) classification has unified these entities as precursor B-cell and T-cell lymphoblastic leukemia/lymphoma. (medscape.com)
Lymphoblastic lymphoma is aggressive and progresses rapidly, presenting as stage IV disease in more than 70% of patients (see Staging). (medscape.com)

These include differences in anatomy, physiology, pharmacokinetics, disease incidence and morbidity with certain infectious diseases. (ivis.org)
A 9-month-old girl was admitted to our department of paediatric infectious diseases in Samsun, Turkey with complaints of swelling on the right side of her neck and a draining lesion on her right forearm over the previous 2 months. (who.int)

Case 16-2022: A 55-Year-Old Man with Fevers, Night Sweats, and a Mediastinal Mass. N Engl J Med. (harvard.edu)
TAFRO Syndrome with an Anterior Mediastinal Mass and Lethal Autoantibody-Mediated Thrombocytopenia: An Autopsy Case Report. (harvard.edu)
In this report, a successful double lumen endobronchial intubation using "subcutaneous dissociative conscious sedation" as a novel method in the management of compromised airway (a case of a mediastinal mass) is presented. (scirp.org)
Clinical features: A 42 year- old, 62 Kg man was presented for an open biopsy of a middle mediastinal mass. (scirp.org)
S. Viswanathan, C. E. Campbell and R. C. Cork, "Asymptomatic Undetected Mediastinal Mass: A Death during Ambulatory Anesthesia," Journal of Clinical Anesthesiology, 1995, 7: 151-155. (scirp.org)
R. K. Sharma, L. Swain and N. Dave, "Anesthetic Management of a Patient with Malignant Mediastinal Mass," Indian Journal of Anaesthesia, Vol. 47, 2003, pp. 205207. (scirp.org)
P. Slinger and C. Karsli, "Management of the Patient with a Large Anterior Mediastinal Mass: Recurring Myths," Current Opinion in Anesthesiology, Vol. 20, No. 1, 2007, pp. 1-3. (scirp.org)

Clinical studies are part of clinical research and at the heart of all medical advances, including rare diseases. (nih.gov)
Clinical trials determine if a new test or treatment for a disease is effective and safe by comparing groups receiving different tests/treatments. (nih.gov)
People with a disease may participate to receive the newest possible treatment and additional care from clinical study staff as well as to help others living with the same or similar disease. (nih.gov)
For example, if clinical staging reveals stage IIIB or IV disease, surgery is not helpful and no pathological staging information will be obtained (appropriately). (wikipedia.org)
In this review, we consider the treatment of HL in younger patients, first evaluating recent clinical trials for early-stage disease, with a special focus on which patients may still need radiotherapy (RT). (cancernetwork.com)
Clinical imaging of MM and related diseases with PET/CT uses 18 F-labeled FDG, with other PET radiopharmaceuticals still investigational. (snmjournals.org)
The authors report a 4-year-old male with Hodgkin's disease with atypical clinical presentation, laboratory data and imaging studies as well as an increased radiosensitivity. (hindawi.com)
General reference Idiopathic interstitial pneumonias (IIPs) are interstitial lung diseases of unknown etiology that share similar clinical and radiologic features and are distinguished primarily by the histopathologic. (merckmanuals.com)
Suspected chronic beryllium disease (CBD) is a clinical indication for bronchoscopy. (cdc.gov)
Between February 2009 and July 2013, 402 patients with clinical stage I non-small cell lung cancer (NSCLC) underwent "non-grasping en bloc MLND" conducted by one surgical team. (medscape.com)

We perform detailed anatomic, functional, and physiologic imaging of the coronary arteries, myocardium, cardiac chambers, valves, aorta, pulmonary arteries, and pericardium using cardiac magnetic resonance imaging (MRI) and computed tomography (CT) in adults and pediatric patients suffering from a broad range of congenital and acquired cardiac diseases. (ohsu.edu)

Centers for Disease Control and Prevention. (cdc.gov)
FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION disease was confirmed in two patients, had two thoracenteses that produced se- view indicated mediastinal widening. (cdc.gov)
Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)

Our focus is on thorough evaluation and tailored surgical treatment in the areas of airway diagnostics, pleural disease, foregut oncology, GERD and swallowing, lung cancer, minimally invasive thoracic surgery, thoracic oncology, mediastinal diseases and hyperhidrosis. (swedish.org)

Our surgeons perform over 800 diagnostic procedures and 1,000 major surgeries each year encompassing a comprehensive range of airway, thoracic, esophageal and gastric diseases. (swedish.org)

D. Bitter, "Respiratory Obstruction Associated with Induction of General Anesthesia in a Patient with Mediastinal Hodgkin's Disease," Anesthesia & Analgesia, Vol. 54, No. 3, 1975, pp. 399-403. (scirp.org)
METHODS Fresh tissue samples (node or lung biopsy) taken from 23 patients with newly diagnosed sarcoidosis, 10 with other respiratory disease, and four patients with culture positive tuberculosis were analysed using PCR to amplify a 123 bp fragment of IS6110, the insertion element present in MTb, and nested PCR to further amplify an 85 bp sequence within the 123 bp product. (bmj.com)
RESULTS MTb DNA was not detected in any of the tissue samples from patients with sarcoidosis or other respiratory disease but was found in all four patients with tuberculosis. (bmj.com)
Ten patients with other respiratory disease undergoing lung biopsy or mediastinoscopy acted as negative controls, and four patients with tuberculosis and culture positive nodes acted as positive controls. (bmj.com)
However, there are a number of significant features peculiar to the donkey that practitioners should be aware of when attempting to investigate and treat respiratory disease. (ivis.org)
The WTC Cough Syndrome (a chronic cough syndrome, thought to be a consequence of upper and lower respiratory disease typically including chronic asthmatic bronchitis, chronic rhinosinusitis, chronic gastroesophageal reflux, or any combination of the three) has been reported by a large percentage of the exposed. (cdc.gov)
33 Occurrences of WTC respiratory disease in rescue workers/volunteers whose first exposure was more than 48 hours post-collapse could be explained either by "high-level" exposures generated by activities that disturbed dust in place, while entering enclosed, poorly ventilated areas, or by the accumulation of repeated "low-level" exposures over time. (cdc.gov)
Histoplasmosis is one of the most common endemic mycosis in the United States and encompasses a spectrum of disease ranging from self-limited respiratory illness to disseminated infection (1-2). (cdc.gov)

Sudish Murthy, MD, PhD is the Section Head of Thoracic Surgery, the Daniel and Karen Lee Endowed Chair in Thoracic Surgery, Surgical Director of the Center of Major Airway Disease, and a Staff Thoracic Surgeon in the Department of Thoracic and Cardiovascular Surgery at The Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute at Cleveland Clinic. (clevelandclinic.org)
Recent studies have demonstrated that combination endobronchial ultrasound-guided fine needle aspiration (EBUS-FNA) and endoscopic ultrasound (EUS)-FNA is less invasive, offers near complete mediastinal staging (as well as the ability to diagnose M1 disease), and may afford superior diagnostic sensitivity in comparison with the standard surgical approach. (medpagetoday.com)
We offer a complete range of thoracic surgical procedures with an emphasis on thoracic oncology and benign diseases of the esophagus. (swedish.org)
A triathlete, and colon and rectal surgeon with Dignity Health Cancer Institute at St. Joseph's, Dr. Anathea Powell's medical expertise includes surgical treatment of all colon, rectal and anal conditions, including cancer, inflammatory bowel disease, hemorrhoids, and other anal problems. (dignityhealth.org)

Persons with a history of pulmonary disease can develop chronic pulmonary histoplasmosis. (cdc.gov)
1 , 9 In persons who develop progressive, chronic, or disseminated disease, symptoms may persist for months or longer. (cdc.gov)

Non-grasping en bloc MLND enables en bloc dissection of mediastinal LNs with comparable morbidity and oncological efficacy while saving troubles of excessive interference of instruments and potential damage to the target LN. (medscape.com)

Rare Disease PHGKB is an online, continuously updated, searchable database of published scientific literature, CDC and NIH resources, and other information that address the public health impact and translation of genomic and other precision health discoveries into improved health outcomes related to rare diseases. (cdc.gov)

D. R. Northrip, B. K. Bohman and K. Tsueda, "Total Airway Occlusion and Superior Vena Cava Syndrome in a Child with Anterior Mediastinal Tumour," Anesthesia & Analgesia, Vol. 65, No. 10, 1986, pp. 1079-1082. (scirp.org)

This often poses diagnostic challenges because of the complexity of the mediastinal anatomic structures. (allenpress.com)

MM has 3 components: diffuse marrow infiltration, focal bone lesions, and soft-tissue (extramedullary) disease. (snmjournals.org)
Tissue biopsy of metastatic sites (including supraclavicular and mediastinal nodes and pleura) helps to assess disease extent. (family-health-information.com)
The aim of this study was to collect prospectively tissue from a carefully characterised cohort of patients with newly diagnosed sarcoidosis in whom tuberculous infection or prior disease had been excluded and to use PCR to search for DNA sequences specific for MTb. (bmj.com)
A mediastinal tumor resection removes abnormal tissue in this area. (epnet.com)

Fine-needle aspiration cytology plays a vital role in evaluation of mediastinal lesions. (allenpress.com)

Although the lungs are the initial site of infection, disease can spread to many organs. (msdmanuals.com)

If you are ill from any disease or notice medical symptoms, you should consult your doctor. (family-health-information.com)
Acute pulmonary histoplasmosis is the most common form of disease, and symptoms typically include fever, headache, malaise, and cough. (cdc.gov)

Distinct repeat infections have also been reported, typically involving acute pulmonary disease in endemic areas. (cdc.gov)

A Prospective Trial of Radiation Alone vs Combination Chemotherapy Alone for Early-Stage Hodgkin's Disease: Implications of 25-Year Follow-Up to Current Combined Modality Therapy. (yale.edu)
Longo D, Glatstein E, Duffey P, Young R, Fiem S, Jaffe E, Camphausen K, Wilson W, DeVita V . A Prospective Trial of Radiation Alone vs Combination Chemotherapy Alone for Early-Stage Hodgkin's Disease: Implications of 25-Year Follow-Up to Current Combined Modality Therapy. (yale.edu)
After partial resection of the tumor the histology indicated Hodgkin's disease-mixed cellularity. (hindawi.com)
C. Sandoval and M. Swift, "Hodgkin's disease in ataxia-telangiectasia patients with poor outcomes," Medical and Pediatric Oncology , vol. 40, no. 3, pp. 162-166, 2003. (hindawi.com)
R. Y. J. Tamminga, W. V. Dolsma, J. A. Leeuw, and H. H. Kampinga, "Chemo- and radiosensitivity testing in a patient with ataxia telangiectasia and Hodgkin's disease," Pediatric Hematology and Oncology , vol. 19, no. 3, pp. 163-171, 2002. (hindawi.com)
The concept of the GPOH-HD 2003 therapy study for pediatric Hodgkin's disease: evolution in the tradition of the DAL/GPOH studies," Klinische Pädiatrie , vol. 216, no. 3, pp. 150-156, 2004. (hindawi.com)
Immunodeficiency and Hodgkin's disease: treatment and outcome in the DAL HD78-90 and GPOH HD95 studies," Klinische Pädiatrie , vol. 215, no. 6, pp. 315-320, 2003. (hindawi.com)

Elevated Serum Small Dense Low-Density Lipoprotein Cholesterol May Increase the Risk and Severity of Coronary Heart Disease and Predict Cardiovascular Events in Patients with Type 2 Diabetes Mellitus. (nih.gov)

Ectopic Anterior Mediastinal Pancreas: An Unusual Case of New Onset Hemoptysis. (harvard.edu)
Hypercalcemia is a common paraneoplastic syndrome noted in the anterior mediastinal form. (dvm360.com)

For advanced disease, prognostic factors may provide information for those wishing to use treatment other than the ABVD regimen (Table 1) or other standard chemotherapy regimens. (cancernetwork.com)
Regimens that combine chemotherapy and radiation therapy (RT) have replaced RT alone for treatment of early-stage, favorable disease. (medscape.com)
In some cases where a patient with limited stage disease has only one small tumor, the tumor will be surgically removed, followed by chemotherapy. (family-health-information.com)

Fine-needle aspiration cytology (FNAC) was first introduced by Martin and Ellis 4 and has been used as an easy and safe procedure for diagnosing primary and metastatic mediastinal diseases. (allenpress.com)

The unusual finding of extensive mediastinal disease raised the possibility that the patient had inhalational melioidosis. (cdc.gov)

Tuberculosis (TB) properly refers only to disease caused by Mycobacterium tuberculosis (for which humans are the main reservoir). (msdmanuals.com)
It is a disease caused by strains of Mycobacterium tuberculosis that are resistant to at least isoniazid and rifampicin, the 2 most powerful first-line anti-tuberculosis drugs (1-3). (who.int)

Severe pulmonary disease can involve a wide range of complications (3). (cdc.gov)

The young patient with HL treated in the past had a greater chance of dying of some malignancy other than HL, and at an earlier age than someone who has not had the disease. (cancernetwork.com)
Relapse therapy can cure approximately 50% of patients, depending on patient- and disease-related features, and failure of initial therapy, once considered an ominous sign, may not be such a poor feature any longer. (cancernetwork.com)
Newer therapy options are needed for the disease-not only novel initial therapy designed to treat the patient with minimal complications, but also therapy for those in relapse. (cancernetwork.com)
Further laboratory evaluation for a patient with a positive initial workup for CBD is performed to determine disease progression. (cdc.gov)

Newer therapeutic options are still needed for the disease, to minimize complications and to improve the treatment of patients in relapse. (cancernetwork.com)
Still, physicians face dilemmas in therapy for the disease, and many cured patients live with complications of treatment. (cancernetwork.com)
Recent trials suggest that ABVD or variants of this combination with or without RT may still be the best therapy for early-stage HL, regardless of the type of disease presentation, and the potential for complications of therapy may ultimately direct choices of treatment. (cancernetwork.com)

Diseases13

Chemicals and Drugs1

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Information Science1

Health Care2

Tumors9

Lymph8

Metastatic disease4

Masses12

Hilar1

Diagnosis7

Interstitial Lung Di3

Chest5

Emphysema2

Lymphoma8

Infectious diseases2

Mass7

Clinical10

Computed Tomography1

Centers for Diseas4

Hyperhidrosis1

Esophageal1

Respiratory8

Surgical4

Chronic2

Morbidity1

PHGKB1

Airway1

Structures1

Tissue4

Lesions1

Lungs1

Symptoms2

Infections1

Hodgkin's7

Coronary Heart D1

Anterior2

Chemotherapy3

Primary1

Inhalational1

Tuberculosis2

Pulmonary disease1

Patient4

Complications3