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  • form of macular
  • Although BVMD is an autosomal dominant form of macular dystrophy, expressivity varies within and between affected families although the overwhelming majority of affected families come from northern European descent. (wikipedia.org)
  • capillary
  • Cystoid macular edema (CME) involves fluid accumulation in the outer plexiform layer secondary to abnormal perifoveal retinal capillary permeability. (wikipedia.org)
  • Findings include delayed venous filling, hypofluorescence caused by hemorrhage and capillary nonperfusion, dilation and tortuosity of veins, leakage due to neovascularization and macular edema. (wikipedia.org)
  • The intraocular levels of VEGF are increased in eyes with macular edema secondary to BRVO and the elevated VEGF levels are correlated to the degree and severity of the areas of capillary nonperfusion and macular edema. (wikipedia.org)
  • therapeutic development
  • This report provides comprehensive information on the therapeutic development for Diabetic Macular Edema, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. (mynewsdesk.com)
  • It also reviews key players involved in the therapeutic development for Diabetic Macular Edema and special features on late-stage and discontinued projects. (mynewsdesk.com)
  • The Macular Edema (Ophthalmology) pipeline guide also reviews of key players involved in therapeutic development for Macular Edema and features dormant and discontinued projects. (aarkstore.com)
  • secondary
  • DME is a consequence of DR in the macular area and is secondary to retinal barrier rupture, which is in turn secondary to a range of metabolic changes brought about by hyperglycemia [ 4 ]. (hindawi.com)
  • Ophthalmology
  • Global Markets Directs latest Pharmaceutical and Healthcare disease pipeline guide Macular Edema - Pipeline Review, H2 2017, provides an overview of the Macular Edema (Ophthalmology) pipeline landscape. (aarkstore.com)
  • Global Markets Directs Pharmaceutical and Healthcare latest pipeline guide Macular Edema - Pipeline Review, H2 2017, provides comprehensive information on the therapeutics under development for Macular Edema (Ophthalmology), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. (aarkstore.com)
  • Macular Edema (Ophthalmology) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. (aarkstore.com)
  • The pipeline guide provides a snapshot of the global therapeutic landscape of Macular Edema (Ophthalmology). (aarkstore.com)
  • The pipeline guide reviews pipeline therapeutics for Macular Edema (Ophthalmology) by companies and universities/research institutes based on information derived from company and industry-specific sources. (aarkstore.com)
  • The pipeline guide reviews key companies involved in Macular Edema (Ophthalmology) therapeutics and enlists all their major and minor projects. (aarkstore.com)
  • The pipeline guide evaluates Macular Edema (Ophthalmology) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. (aarkstore.com)
  • Find and recognize significant and varied types of therapeutics under development for Macular Edema (Ophthalmology). (aarkstore.com)
  • Formulate corrective measures for pipeline projects by understanding Macular Edema (Ophthalmology) pipeline depth and focus of Indication therapeutics. (aarkstore.com)
  • fluid
  • Macular edema is the build-up of fluid in the macula, an area in the center of the retina. (nih.gov)
  • Macular edema is swelling or fluid retention in a specialized part of the retina called the macula. (aarkstore.com)
  • Macular edema occurs when fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken and swell (edema). (wikipedia.org)
  • vision
  • This leads to macular swelling, causing blurred vision. (drugs.com)
  • Macular edema (ME) is a condition characterized by the thickening and swelling (edema) of the macula, which is the area of the retina that is responsible for central vision. (medgadget.com)
  • Even macular edema, which can cause rapid vision loss, may not have any warning signs for some time. (wikipedia.org)
  • In general, however, a person with macular edema is likely to have blurred vision, making it hard to do things like read or drive. (wikipedia.org)
  • bilateral
  • Presentation varies slightly compared to adults with bilateral involvement, uveitis, disc edema and tissue eosinophilia being more common in this population. (wikipedia.org)
  • Patients
  • Optical Coherence Tomography (OCT) is a type of high-resolution ultrasound used to evaluate the macular anatomy and to rule out cystoid macular edema (DME) or macular atrophy (Macular Ischemia) in PDR patients (rpa--ip-OCT). (retinacenternj.com)
  • Many patients with PDR have loss of normal capillary circulation in the macula (macular ischemia) & peripheral retina (peripheral ischemia), growth of new blood vessels on the optic nerve (NVD), retina (NVE), iris (NVI) or angle (NVE) on the FA. (retinacenternj.com)
  • Because TNF-α is known to break down the blood-retinal barrier, the improvements in our case suggest that TNF-α plays a role in the pathogenesis of macular edema in some patients with BRVO. (dovepress.com)
  • oedema
  • Unfortunately, about a week after surgery my vision began to deteriorate and become blurred, especially at night, so now I'm going back to the hospital tomorrow as I suspect I have post op macular oedema. (vision-and-eye-health.com)
  • disc edema
  • Presentation varies slightly compared to adults with bilateral involvement, uveitis, disc edema and tissue eosinophilia being more common in this population. (wikipedia.org)
  • Spontaneous venous pulsations are present in about 80 percent of patients with ODD, but absent in cases of true disc edema. (wikipedia.org)
  • Bevacizumab
  • Este estudo parece fornecer evidências para apoiar o uso de triancinolona intravítrea ou bevacizumab no momento da cirurgia de catarata em casos com edema macular diabético preexistente (DME) ou retinopatia diabética não-proliferativa moderada a grave. (unifesp.br)
  • Hole
  • There is evidence that symptomatic VMA can contribute to the development of several well-known eye disorders, such as macular hole and macular pucker, that can cause visual impairment, including blindness. (wikipedia.org)
  • blood vessels
  • The pulling forces or traction from this adhesion on the retinal surface can sometimes cause edema within the retina, damage to retinal blood vessels causing bleeding, or damage to the optic nerve causing disruption in the nerve signals sent to the brain for visual processing. (wikipedia.org)
  • type
  • The source of leakage was defined in FA images by detecting microaneurysms, capillary non-perfusion or capillary leakage depending on the individual edema type graded by the SAVE grading system. (arvojournals.org)
  • area
  • The size of NPA (9.02±5.34mm) and thinning area (7.22±5.72mm) at macular area (6mm×6mm) showed a significant correlation (p=0.003,r=0.971). (arvojournals.org)
  • results
  • 102), and the results sholud multifocal ERGs support the wh at made by full-field and focal macular ERGs (Fig.Okonek, M. Acta Anaesthesiol Ital 1983;3491. (luxbar-starway.ru)
  • shown
  • AZ2171 (cediranib), a multi-targeted tyrosine kinase inhibitor has been shown to have anti-edema effects by reducing the permeability and aiding in vascular normalization. (wikipedia.org)